AR241439A1 - Preparacion de n-tiazolil-metiltio-alquil-n'-(ciano, carbamoil, nitro p-alquilfenilsulfonil o alquilsulfonil) guanidinas o n'-ciano carbamido tioatos. - Google Patents
Preparacion de n-tiazolil-metiltio-alquil-n'-(ciano, carbamoil, nitro p-alquilfenilsulfonil o alquilsulfonil) guanidinas o n'-ciano carbamido tioatos.Info
- Publication number
- AR241439A1 AR241439A1 AR82291229A AR29122982A AR241439A1 AR 241439 A1 AR241439 A1 AR 241439A1 AR 82291229 A AR82291229 A AR 82291229A AR 29122982 A AR29122982 A AR 29122982A AR 241439 A1 AR241439 A1 AR 241439A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- formula
- compounds
- relating
- thiazole derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
UN PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE N-ALQUIL-N'-(2- (DIALQUILAMINOALQUILO)-4- TIAZOLIL)METILTIO)-ALQUIL-N'-(CIANO, CARBAMOIL, NITRO P-ALQUILFENILSULFONIL O ALQUILSULFONIL)GUANIDINA O N''- CIANOCARBAMIDOTIOATOS DE ALQUILO DE FORMULA I, DONDE N ES 1 O 2; R1 Y R2 SON ALQUILO; ALK ES ALQUILENO; R ES -CN; -CONH2; P-ALQUIL FENIL SO2-; NO2- ALQUILO -SO2- Y RX ES NH-ALQUILO Y SUSSALES QUE COMPRENDE HACER REACCIONAR UN COMPUESTO DE FORMULA II, CON UN REACTIVO DE FORMULA III, DONDE R1 Y R2 TIENEN EL SIGNIFICADO SENALADO Y RY ES - CN O P-ALQUIL(-FENIL-SO2- O ALQUIL -SO2 - YHACER REACCIONAR LOS COMPUESTOS OBTENIDOS CON UNA AMINA DE FORMULA ALQUILO -NH2, PARA OBTENER LOS COMPUESTOS DE FORMULA (I) DONDE RX ES -NH- ALQUILO, OBTENIENDOSE LOS COMPUESTOS DE FORMULA (I) DONDE R ES -CONH2 POR HIDROLISIS EN MEDIO ACIDO DE LOS COMPUESTOS OBTENIDOS DONDE R ES -CN, N ES 1 O 2.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/193,192 US4375547A (en) | 1980-10-02 | 1980-10-02 | N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine |
Publications (1)
Publication Number | Publication Date |
---|---|
AR241439A1 true AR241439A1 (es) | 1992-07-31 |
Family
ID=22712591
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR82291229A AR241439A1 (es) | 1980-10-02 | 1982-11-09 | Preparacion de n-tiazolil-metiltio-alquil-n'-(ciano, carbamoil, nitro p-alquilfenilsulfonil o alquilsulfonil) guanidinas o n'-ciano carbamido tioatos. |
Country Status (36)
Country | Link |
---|---|
US (1) | US4375547A (es) |
EP (1) | EP0049618B1 (es) |
JP (1) | JPS5791980A (es) |
KR (1) | KR850001795B1 (es) |
AR (1) | AR241439A1 (es) |
AU (1) | AU542553B2 (es) |
BG (1) | BG60249B1 (es) |
CA (1) | CA1166248A (es) |
CS (1) | CS227015B2 (es) |
CY (1) | CY1351A (es) |
DD (1) | DD200371A5 (es) |
DE (1) | DE3171819D1 (es) |
DK (2) | DK164056C (es) |
EG (1) | EG15678A (es) |
ES (2) | ES505950A0 (es) |
FI (2) | FI813058L (es) |
GB (1) | GB2084581B (es) |
GR (1) | GR75023B (es) |
HK (1) | HK15987A (es) |
HU (1) | HU188697B (es) |
IE (1) | IE51603B1 (es) |
IL (1) | IL63980A (es) |
LU (1) | LU88293I2 (es) |
MX (1) | MX5723A (es) |
MY (1) | MY8700247A (es) |
NL (1) | NL930107I2 (es) |
NO (1) | NO155885C (es) |
NZ (1) | NZ198523A (es) |
PH (1) | PH18135A (es) |
PL (2) | PL130526B1 (es) |
PT (1) | PT73757B (es) |
RO (2) | RO82215A (es) |
SU (1) | SU1184443A3 (es) |
UA (1) | UA6081A1 (es) |
YU (1) | YU42728B (es) |
ZA (1) | ZA816817B (es) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4904792A (en) * | 1980-10-02 | 1990-02-27 | Eli Lilly And Company | N-thiazolymethylthioalkyl-N'-alkylamidines and related compounds |
NZ202797A (en) * | 1981-12-28 | 1985-08-30 | Lilly Co Eli | Pyrimidine derivatives and pharmaceutical compositions |
US4474794A (en) * | 1982-03-19 | 1984-10-02 | Eli Lilly And Company | N-Thiazolylmethylthioalkyl-N1 -alkenyl (or alkynyl)guanidines and related compounds |
FR2531703A1 (fr) * | 1982-08-13 | 1984-02-17 | Sanofi Sa | 2-aza-5-thiahexan-1-ones 1,6-disubstituees, leurs sels, procede pour leur preparation et compositions pharmaceutiques les renfermant |
US4587344A (en) * | 1983-02-07 | 1986-05-06 | Eli Lilly And Company | Isothiourea synthesis process |
UA6020A1 (uk) * | 1983-02-07 | 1994-12-29 | Елі Ліллі Енд Компані | Спосіб одержання n-метіл-n-/2-(2-діметіламінометіл тіазол-4-ілметілтіо)-етіл/-2-нітро-1,1-етендіаміна |
US4468517A (en) * | 1983-05-12 | 1984-08-28 | Eli Lilly And Company | Synthesis of thiazoles |
DE3417127A1 (de) * | 1984-05-09 | 1985-11-14 | Papst-Motoren GmbH & Co KG, 7742 St Georgen | Kleinstventilator |
DE3531504A1 (de) * | 1985-09-04 | 1987-03-12 | Basf Ag | 3-aminomethylpyrrol-1-yl-alkylamine und diese verbindungen enthaltende therapeutische mittel |
US4777260A (en) * | 1985-12-18 | 1988-10-11 | Eli Lilly And Company | Synthesis of nizatidine intermediate |
CA1277325C (en) * | 1985-12-18 | 1990-12-04 | Bruce A. Slomski | Synthesis of nizatidine |
EP0285681B1 (de) * | 1987-04-06 | 1993-03-10 | HEUMANN PHARMA GMBH & CO | Verfahren zur Herstellung von Nitroethenderivaten |
ES2007959A6 (es) * | 1988-07-11 | 1989-07-01 | Vinas Lab | Procedimiento para la obtencion de derivados tiazolicos. |
ES2151480T3 (es) * | 1991-05-21 | 2001-01-01 | Lilly Co Eli | Procedimiento para preparar productos intermedios de nizatidina y compuestos relacionados. |
ES2038922B1 (es) * | 1991-12-30 | 1994-04-16 | Fermentaciones Y Sintesis Espa | Procedimiento para la obtencion de nizatidina. |
US5294433A (en) * | 1992-04-15 | 1994-03-15 | The Procter & Gamble Company | Use of H-2 antagonists for treatment of gingivitis |
US5574054A (en) * | 1992-05-12 | 1996-11-12 | Zeria Pharmaceutical Co., Ltd. | Quaternary ammonium salts and use thereof as medicine |
US5541335A (en) * | 1994-07-11 | 1996-07-30 | Torcan Chemical Ltd. | Process for preparing nizatidine |
US5470865A (en) * | 1994-08-30 | 1995-11-28 | Eli Lilly And Company | Pharmaceutical composition |
CA2265435A1 (en) * | 1996-09-11 | 1998-03-19 | Knoll Aktiengesellschaft | Process for the preparation of nizatidine |
IT1299198B1 (it) * | 1998-03-05 | 2000-02-29 | Nicox Sa | Sali nitrati di farmaci antiulcera |
US6552047B2 (en) | 1998-11-17 | 2003-04-22 | Nitromed, Inc. | H2 receptor antagonist compounds in combination with nitric oxide donors, compositions and methods of use |
US8980894B2 (en) | 2004-03-25 | 2015-03-17 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure |
EP1579862A1 (en) | 2004-03-25 | 2005-09-28 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure |
US20080044481A1 (en) * | 2004-05-27 | 2008-02-21 | Mordechai Harel | Microparticles for Oral Delivery |
US20080045575A1 (en) * | 2004-12-29 | 2008-02-21 | Van Dyke Thomas E | Delivery of H2 Antagonists |
EP1920785A1 (en) | 2006-11-07 | 2008-05-14 | Boehringer Ingelheim Vetmedica Gmbh | Liquid preparation comprising a complex of pimobendan and cyclodextrin |
US20090275622A1 (en) * | 2008-04-30 | 2009-11-05 | Prasoona Linga | Nizatidine formulations |
EP2825159B1 (en) | 2012-03-15 | 2022-06-22 | Boehringer Ingelheim Vetmedica GmbH | Pharmaceutical tablet formulation for the veterinary medical sector, method of production and use thereof |
CN105377235A (zh) | 2013-07-19 | 2016-03-02 | 勃林格殷格翰动物保健有限公司 | 含有防腐的醚化的环糊精衍生物的液体水性药物组合物 |
ES2883448T3 (es) | 2013-12-04 | 2021-12-07 | Boehringer Ingelheim Vetmedica Gmbh | Composiciones farmacéuticas mejoradas de pimobendán |
EP2929884A1 (en) | 2014-04-11 | 2015-10-14 | Sanovel Ilac Sanayi ve Ticaret A.S. | Pharmaceutical combinations of dabigatran and h2-receptor antagonists |
EP2942058A1 (en) | 2014-05-09 | 2015-11-11 | Sanovel Ilac Sanayi ve Ticaret A.S. | Pharmaceutical combinations of rivaroxaban and H2-receptor antagonists |
US10537570B2 (en) | 2016-04-06 | 2020-01-21 | Boehringer Ingelheim Vetmedica Gmbh | Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease |
EP4196793A1 (en) | 2020-08-11 | 2023-06-21 | Université de Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1338169A (en) * | 1971-03-09 | 1973-11-21 | Smith Kline French Lab | Ureas thioureas and guanidines |
US3917593A (en) * | 1972-05-22 | 1975-11-04 | Smithkline Corp | N-alkenyl and N-alkynyl (2-quinolyl)thio-acetamides |
US3853865A (en) * | 1972-06-26 | 1974-12-10 | Smithkline Corp | N-aminomethyl-2-amino(and 2-amino-methyl)-2-heterocyclic-thioacetamides |
GB1421792A (en) * | 1973-05-17 | 1976-01-21 | Smith Kline French Lab | Heterocyclic substituted-1, 1-diamino-ethylene derivatives methods for their preparation and compositions containing them |
US4191769A (en) * | 1974-03-12 | 1980-03-04 | Smith Kline & French Laboratories Limited | Isothiourea compounds and pharmacological use |
US4061637A (en) * | 1974-05-14 | 1977-12-06 | Istituto Luso Farmaco D'italia S.R.L. | Certain 4-aryl-5-(4-phenylpiperazino)alkyl-4-thiazolin-2-ones |
US4173644A (en) * | 1975-02-03 | 1979-11-06 | Smith Kline & French Laboratories Limited | Thiourea compounds, compositions and methods and use |
US4166856A (en) * | 1975-05-21 | 1979-09-04 | Smith Kline & French Laboratories Limited | Thiazole and isothiazole derivative as blockers of histamine H2 -receptors |
GB1574214A (en) * | 1976-03-11 | 1980-09-03 | Smith Kline French Lab | Amidines |
GB1602458A (en) * | 1977-05-05 | 1981-11-11 | Smith Kline French Lab | Bisamidines as histamine h2-antagonists |
JPS5444660A (en) * | 1977-08-29 | 1979-04-09 | Yamanouchi Pharmaceut Co Ltd | Heterocyclic compound and its preparation |
DE2835695A1 (de) * | 1977-08-29 | 1979-03-15 | Yamanouchi Pharma Co Ltd | Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten |
US4210658A (en) * | 1977-09-08 | 1980-07-01 | Smith Kline & French Laboratories Limited | Amidinosulphonic acid derivatives |
DE2905134A1 (de) * | 1978-02-17 | 1979-08-23 | Degussa | Neue acylierte aminoalkyl-cyanoguanidine mit einem heterocyclischen rest |
DE2963363D1 (en) * | 1978-05-24 | 1982-09-09 | Ici Plc | Antisecretory thiadiazole derivatives, processes for their manufacture and pharmaceutical compositions containing them |
US4200578A (en) * | 1978-12-18 | 1980-04-29 | Bristol-Myers Company | Thiazole derivatives |
-
1980
- 1980-10-02 US US06/193,192 patent/US4375547A/en not_active Expired - Lifetime
-
1981
- 1981-10-01 NZ NZ198523A patent/NZ198523A/en unknown
- 1981-10-01 PH PH26296A patent/PH18135A/en unknown
- 1981-10-01 YU YU2364/81A patent/YU42728B/xx unknown
- 1981-10-01 AU AU75945/81A patent/AU542553B2/en not_active Expired
- 1981-10-01 ZA ZA816817A patent/ZA816817B/xx unknown
- 1981-10-01 UA UA3344304A patent/UA6081A1/uk unknown
- 1981-10-01 FI FI810358A patent/FI813058L/fi not_active Application Discontinuation
- 1981-10-01 PT PT73757A patent/PT73757B/pt unknown
- 1981-10-01 DK DK435181A patent/DK164056C/da not_active IP Right Cessation
- 1981-10-01 ES ES505950A patent/ES505950A0/es active Granted
- 1981-10-01 HU HU812844A patent/HU188697B/hu unknown
- 1981-10-01 RO RO81105440A patent/RO82215A/ro unknown
- 1981-10-01 SU SU813344304A patent/SU1184443A3/ru active
- 1981-10-01 NO NO813334A patent/NO155885C/no not_active IP Right Cessation
- 1981-10-01 IL IL63980A patent/IL63980A/xx not_active IP Right Cessation
- 1981-10-01 RO RO110860A patent/RO85815B/ro unknown
- 1981-10-01 IE IE2285/81A patent/IE51603B1/en not_active IP Right Cessation
- 1981-10-01 FI FI813058A patent/FI76570C/fi not_active IP Right Cessation
- 1981-10-01 CS CS817182A patent/CS227015B2/cs unknown
- 1981-10-01 CA CA000387139A patent/CA1166248A/en not_active Expired
- 1981-10-02 DD DD81233851A patent/DD200371A5/de unknown
- 1981-10-02 GR GR66193A patent/GR75023B/el unknown
- 1981-10-02 DE DE8181304572T patent/DE3171819D1/de not_active Expired
- 1981-10-02 KR KR1019810003721A patent/KR850001795B1/ko active
- 1981-10-02 JP JP56158594A patent/JPS5791980A/ja active Granted
- 1981-10-02 CY CY135181A patent/CY1351A/xx unknown
- 1981-10-02 GB GB8129855A patent/GB2084581B/en not_active Expired
- 1981-10-02 BG BG053730A patent/BG60249B1/bg unknown
- 1981-10-02 EP EP81304572A patent/EP0049618B1/en not_active Expired
- 1981-10-02 PL PL1981233295A patent/PL130526B1/pl unknown
- 1981-10-02 PL PL1981238035A patent/PL130626B1/pl unknown
- 1981-10-03 EG EG566/81A patent/EG15678A/xx active
-
1982
- 1982-08-09 ES ES514868A patent/ES8306135A1/es not_active Expired
- 1982-11-09 AR AR82291229A patent/AR241439A1/es active
-
1986
- 1986-11-25 MX MX572386A patent/MX5723A/es unknown
-
1987
- 1987-02-19 HK HK159/87A patent/HK15987A/xx not_active IP Right Cessation
- 1987-12-30 MY MY247/87A patent/MY8700247A/xx unknown
-
1991
- 1991-01-24 DK DK012391A patent/DK167759B1/da not_active IP Right Cessation
-
1993
- 1993-06-09 LU LU88293C patent/LU88293I2/fr unknown
- 1993-06-29 NL NL930107C patent/NL930107I2/nl unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR241439A1 (es) | Preparacion de n-tiazolil-metiltio-alquil-n'-(ciano, carbamoil, nitro p-alquilfenilsulfonil o alquilsulfonil) guanidinas o n'-ciano carbamido tioatos. | |
IE811931L (en) | Oxiranes. | |
DK402280A (da) | Fremgangsmaade til fremstilling af diphenulethere | |
DK380680A (da) | Fremgangsmaade til fremstilling af substituerede oxirancarboxylsyrer | |
FI822124A0 (fi) | Tryckkaensligt eller vaermekaensligt uppteckningsmaterial | |
MX173422B (es) | Imidazo-(2,1-b)benzotiazoles y procedimiento para su preparacion | |
AR241182A1 (es) | Un procedimiento para preparar n-(2-metoxifenil)-piperazinil-alcanoil anilidas. | |
JPS56103168A (en) | Thiazole derivative, its preparation, and antihistaminic agent containing the same | |
ES8103030A1 (es) | Un procedimiento para la preparacion de nuevos derivados de benzamida. | |
BR8702904A (pt) | Processo para preparacao de composto herbicida e composicao herbicida | |
ES466887A2 (es) | Un procedimiento de preparacion de una fenilamidina substituida. | |
BR8702905A (pt) | Processo para preparacao de composto herbicida e composicao herbicida | |
ES2054231T3 (es) | Procedimiento para preparar oxido de estireno. | |
TR200002950T2 (tr) | Matris-Metaloproteinaz önleyicilerinin üretiminde faydalı alkilleştirici engellenmiş sülfonamitlerin işlemi. | |
JPS55129255A (en) | Farnesylacetamide compounds or their salts | |
KR840005449A (ko) | 벤조티오 피라노 피리디논 | |
KR910006257A (ko) | 안트라닐산 유도체 및 이를 함유하는 구충제 조성물 | |
ES531933A0 (es) | Un procedimiento para preparar un derivado de imidazolinona | |
JPS55115877A (en) | Novel amidine compound and its preparation | |
ES2059832T3 (es) | Preparacion de acidos 2-(cloro, bromo o nitro)-4-(alquilsulfonil)benzoicos e intermedios. | |
ES2032461T3 (es) | Procedimiento para preparar derivados de indol. | |
HUT43598A (en) | Process for production of derivatives of new 4-hidroxiquinoline carbonic acid and medical compound containing thereof | |
GB1449094A (en) | Poly -dialkyl-phosphonoalkyl- carbamates and their use as flame- retarding agents on textile materials | |
JPS57177058A (en) | Novel fluoran compound | |
JPS559002A (en) | 5-substituted picolinic acid derivative, its preparation and hypotensive agent containing the same |