ES8306135A1 - "un procedimiento para la preparacion de un derivado de tiazol". - Google Patents
"un procedimiento para la preparacion de un derivado de tiazol".Info
- Publication number
- ES8306135A1 ES8306135A1 ES514868A ES514868A ES8306135A1 ES 8306135 A1 ES8306135 A1 ES 8306135A1 ES 514868 A ES514868 A ES 514868A ES 514868 A ES514868 A ES 514868A ES 8306135 A1 ES8306135 A1 ES 8306135A1
- Authority
- ES
- Spain
- Prior art keywords
- relating
- thiazole derivatives
- disubstituted thiazole
- disubstituted
- ethenediamines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE TIAZOL Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R Y R SON HIDROGENO O ALQUILO C <- ; Z ES OXIGENO, AZUFRE O METILENO; R , R , B Y Q PUEDEN SER VARIOS TIPOS DE RADICALES; Y M Y N VALEN 1-3. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UNA AMINA DE FORMULA NHRR , EN LAS QUE L ES UN GRUPO SALIENTE; R Y R PUEDEN SER VARIOS TIPOS DE RADICALES; Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE POLAR, A TEMPERATURAS COMPRENDIDAS ENTRE 20 C Y 100 C. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LAS ULCERAS PEPTI
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/193,192 US4375547A (en) | 1980-10-02 | 1980-10-02 | N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8306135A1 true ES8306135A1 (es) | 1983-05-01 |
ES514868A0 ES514868A0 (es) | 1983-05-01 |
Family
ID=22712591
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES505950A Expired ES8301950A1 (es) | 1980-10-02 | 1981-10-01 | Un procedimiento para la preparacion de un derivado de tia- zol |
ES514868A Granted ES514868A0 (es) | 1980-10-02 | 1982-08-09 | "un procedimiento para la preparacion de un derivado de tiazol". |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES505950A Expired ES8301950A1 (es) | 1980-10-02 | 1981-10-01 | Un procedimiento para la preparacion de un derivado de tia- zol |
Country Status (36)
Country | Link |
---|---|
US (1) | US4375547A (es) |
EP (1) | EP0049618B1 (es) |
JP (1) | JPS5791980A (es) |
KR (1) | KR850001795B1 (es) |
AR (1) | AR241439A1 (es) |
AU (1) | AU542553B2 (es) |
BG (1) | BG60249B1 (es) |
CA (1) | CA1166248A (es) |
CS (1) | CS227015B2 (es) |
CY (1) | CY1351A (es) |
DD (1) | DD200371A5 (es) |
DE (1) | DE3171819D1 (es) |
DK (2) | DK164056C (es) |
EG (1) | EG15678A (es) |
ES (2) | ES8301950A1 (es) |
FI (2) | FI76570C (es) |
GB (1) | GB2084581B (es) |
GR (1) | GR75023B (es) |
HK (1) | HK15987A (es) |
HU (1) | HU188697B (es) |
IE (1) | IE51603B1 (es) |
IL (1) | IL63980A (es) |
LU (1) | LU88293I2 (es) |
MX (1) | MX5723A (es) |
MY (1) | MY8700247A (es) |
NL (1) | NL930107I2 (es) |
NO (1) | NO155885C (es) |
NZ (1) | NZ198523A (es) |
PH (1) | PH18135A (es) |
PL (2) | PL130626B1 (es) |
PT (1) | PT73757B (es) |
RO (2) | RO85815B (es) |
SU (1) | SU1184443A3 (es) |
UA (1) | UA6081A1 (es) |
YU (1) | YU42728B (es) |
ZA (1) | ZA816817B (es) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4904792A (en) * | 1980-10-02 | 1990-02-27 | Eli Lilly And Company | N-thiazolymethylthioalkyl-N'-alkylamidines and related compounds |
NZ202797A (en) * | 1981-12-28 | 1985-08-30 | Lilly Co Eli | Pyrimidine derivatives and pharmaceutical compositions |
US4474794A (en) * | 1982-03-19 | 1984-10-02 | Eli Lilly And Company | N-Thiazolylmethylthioalkyl-N1 -alkenyl (or alkynyl)guanidines and related compounds |
FR2531703A1 (fr) * | 1982-08-13 | 1984-02-17 | Sanofi Sa | 2-aza-5-thiahexan-1-ones 1,6-disubstituees, leurs sels, procede pour leur preparation et compositions pharmaceutiques les renfermant |
US4587344A (en) * | 1983-02-07 | 1986-05-06 | Eli Lilly And Company | Isothiourea synthesis process |
HU190527B (en) * | 1983-02-07 | 1986-09-29 | Eli Lilly And Co,Us | Process for preparing thiazole derivatives |
US4468517A (en) * | 1983-05-12 | 1984-08-28 | Eli Lilly And Company | Synthesis of thiazoles |
DE3417127A1 (de) * | 1984-05-09 | 1985-11-14 | Papst-Motoren GmbH & Co KG, 7742 St Georgen | Kleinstventilator |
DE3531504A1 (de) * | 1985-09-04 | 1987-03-12 | Basf Ag | 3-aminomethylpyrrol-1-yl-alkylamine und diese verbindungen enthaltende therapeutische mittel |
CA1277325C (en) * | 1985-12-18 | 1990-12-04 | Bruce A. Slomski | Synthesis of nizatidine |
US4777260A (en) * | 1985-12-18 | 1988-10-11 | Eli Lilly And Company | Synthesis of nizatidine intermediate |
ATE86619T1 (de) | 1987-04-06 | 1993-03-15 | Heumann Pharma Gmbh & Co | Verfahren zur herstellung von nitroethenderivaten. |
ES2007959A6 (es) * | 1988-07-11 | 1989-07-01 | Vinas Lab | Procedimiento para la obtencion de derivados tiazolicos. |
DE69231541T2 (de) * | 1991-05-21 | 2001-06-07 | Lilly Co Eli | Verfahren zur Herstellung von Zwischenprodukten für Nizatidine und verwandte Verbindungen |
ES2038922B1 (es) * | 1991-12-30 | 1994-04-16 | Fermentaciones Y Sintesis Espa | Procedimiento para la obtencion de nizatidina. |
US5294433A (en) * | 1992-04-15 | 1994-03-15 | The Procter & Gamble Company | Use of H-2 antagonists for treatment of gingivitis |
DE69307310D1 (de) * | 1992-05-12 | 1997-02-20 | Zeria Pharm Co Ltd | Neue quaternäre ammoniumsalze und deren medizinische verwendung |
US5541335A (en) * | 1994-07-11 | 1996-07-30 | Torcan Chemical Ltd. | Process for preparing nizatidine |
US5470865A (en) * | 1994-08-30 | 1995-11-28 | Eli Lilly And Company | Pharmaceutical composition |
TR199900532T2 (xx) * | 1996-09-11 | 1999-05-21 | Knoll Aktiengesellschaft | Nizatidin haz�rlanmas� i�in y�ntem. |
IT1299198B1 (it) | 1998-03-05 | 2000-02-29 | Nicox Sa | Sali nitrati di farmaci antiulcera |
AU772188B2 (en) | 1998-11-17 | 2004-04-08 | Nitromed, Inc. | Nitrosated and nitrosylated H2 receptor antagonist compounds, compositions and methods of use |
US8980894B2 (en) | 2004-03-25 | 2015-03-17 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure |
EP1579862A1 (en) | 2004-03-25 | 2005-09-28 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure |
EP1750674A4 (en) * | 2004-05-27 | 2012-05-23 | Advanced Bionutrition Corp | MICROPARTICLES FOR THE ORAL LEVY |
US20080045575A1 (en) * | 2004-12-29 | 2008-02-21 | Van Dyke Thomas E | Delivery of H2 Antagonists |
EP1920785A1 (en) | 2006-11-07 | 2008-05-14 | Boehringer Ingelheim Vetmedica Gmbh | Liquid preparation comprising a complex of pimobendan and cyclodextrin |
US20090275622A1 (en) * | 2008-04-30 | 2009-11-05 | Prasoona Linga | Nizatidine formulations |
US10398705B2 (en) | 2012-03-15 | 2019-09-03 | Boehringer Ingelheim Vetmedica Gmbh | Pharmaceutical tablet formulation for the veterinary medical sector, method of production and use thereof |
CA2915445C (en) | 2013-07-19 | 2024-04-23 | Boehringer Ingelheim Vetmedica Gmbh | Preserved etherified cyclodextrin derivatives containing liquid aqueous pharmaceutical composition |
PL3106150T3 (pl) | 2013-12-04 | 2022-01-03 | Boehringer Ingelheim Vetmedica Gmbh | Ulepszone kompozycje farmaceutyczne pimobendanu |
EP2929884A1 (en) | 2014-04-11 | 2015-10-14 | Sanovel Ilac Sanayi ve Ticaret A.S. | Pharmaceutical combinations of dabigatran and h2-receptor antagonists |
EP2942058A1 (en) | 2014-05-09 | 2015-11-11 | Sanovel Ilac Sanayi ve Ticaret A.S. | Pharmaceutical combinations of rivaroxaban and H2-receptor antagonists |
US10537570B2 (en) | 2016-04-06 | 2020-01-21 | Boehringer Ingelheim Vetmedica Gmbh | Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease |
US20230349922A1 (en) | 2020-08-11 | 2023-11-02 | Université De Strasbourg | H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1338169A (en) * | 1971-03-09 | 1973-11-21 | Smith Kline French Lab | Ureas thioureas and guanidines |
US3917593A (en) * | 1972-05-22 | 1975-11-04 | Smithkline Corp | N-alkenyl and N-alkynyl (2-quinolyl)thio-acetamides |
US3853865A (en) * | 1972-06-26 | 1974-12-10 | Smithkline Corp | N-aminomethyl-2-amino(and 2-amino-methyl)-2-heterocyclic-thioacetamides |
GB1421792A (en) * | 1973-05-17 | 1976-01-21 | Smith Kline French Lab | Heterocyclic substituted-1, 1-diamino-ethylene derivatives methods for their preparation and compositions containing them |
US4191769A (en) * | 1974-03-12 | 1980-03-04 | Smith Kline & French Laboratories Limited | Isothiourea compounds and pharmacological use |
US4061637A (en) * | 1974-05-14 | 1977-12-06 | Istituto Luso Farmaco D'italia S.R.L. | Certain 4-aryl-5-(4-phenylpiperazino)alkyl-4-thiazolin-2-ones |
US4173644A (en) * | 1975-02-03 | 1979-11-06 | Smith Kline & French Laboratories Limited | Thiourea compounds, compositions and methods and use |
US4166856A (en) * | 1975-05-21 | 1979-09-04 | Smith Kline & French Laboratories Limited | Thiazole and isothiazole derivative as blockers of histamine H2 -receptors |
GB1574214A (en) * | 1976-03-11 | 1980-09-03 | Smith Kline French Lab | Amidines |
GB1602458A (en) * | 1977-05-05 | 1981-11-11 | Smith Kline French Lab | Bisamidines as histamine h2-antagonists |
DE2835695A1 (de) * | 1977-08-29 | 1979-03-15 | Yamanouchi Pharma Co Ltd | Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten |
JPS5444660A (en) * | 1977-08-29 | 1979-04-09 | Yamanouchi Pharmaceut Co Ltd | Heterocyclic compound and its preparation |
US4210658A (en) * | 1977-09-08 | 1980-07-01 | Smith Kline & French Laboratories Limited | Amidinosulphonic acid derivatives |
DE2905134A1 (de) * | 1978-02-17 | 1979-08-23 | Degussa | Neue acylierte aminoalkyl-cyanoguanidine mit einem heterocyclischen rest |
DE2963363D1 (en) * | 1978-05-24 | 1982-09-09 | Ici Plc | Antisecretory thiadiazole derivatives, processes for their manufacture and pharmaceutical compositions containing them |
US4200578A (en) * | 1978-12-18 | 1980-04-29 | Bristol-Myers Company | Thiazole derivatives |
-
1980
- 1980-10-02 US US06/193,192 patent/US4375547A/en not_active Expired - Lifetime
-
1981
- 1981-10-01 UA UA3344304A patent/UA6081A1/uk unknown
- 1981-10-01 CA CA000387139A patent/CA1166248A/en not_active Expired
- 1981-10-01 PT PT73757A patent/PT73757B/pt unknown
- 1981-10-01 PH PH26296A patent/PH18135A/en unknown
- 1981-10-01 CS CS817182A patent/CS227015B2/cs unknown
- 1981-10-01 AU AU75945/81A patent/AU542553B2/en not_active Expired
- 1981-10-01 SU SU813344304A patent/SU1184443A3/ru active
- 1981-10-01 FI FI813058A patent/FI76570C/fi not_active IP Right Cessation
- 1981-10-01 HU HU812844A patent/HU188697B/hu unknown
- 1981-10-01 DK DK435181A patent/DK164056C/da not_active IP Right Cessation
- 1981-10-01 IL IL63980A patent/IL63980A/xx not_active IP Right Cessation
- 1981-10-01 NO NO813334A patent/NO155885C/no not_active IP Right Cessation
- 1981-10-01 FI FI810358A patent/FI813058L/fi not_active Application Discontinuation
- 1981-10-01 ES ES505950A patent/ES8301950A1/es not_active Expired
- 1981-10-01 RO RO110860A patent/RO85815B/ro unknown
- 1981-10-01 RO RO81105440A patent/RO82215A/ro unknown
- 1981-10-01 NZ NZ198523A patent/NZ198523A/en unknown
- 1981-10-01 ZA ZA816817A patent/ZA816817B/xx unknown
- 1981-10-01 IE IE2285/81A patent/IE51603B1/en not_active IP Right Cessation
- 1981-10-01 YU YU2364/81A patent/YU42728B/xx unknown
- 1981-10-02 PL PL1981238035A patent/PL130626B1/pl unknown
- 1981-10-02 GB GB8129855A patent/GB2084581B/en not_active Expired
- 1981-10-02 PL PL1981233295A patent/PL130526B1/pl unknown
- 1981-10-02 DD DD81233851A patent/DD200371A5/de unknown
- 1981-10-02 EP EP81304572A patent/EP0049618B1/en not_active Expired
- 1981-10-02 BG BG053730A patent/BG60249B1/bg unknown
- 1981-10-02 JP JP56158594A patent/JPS5791980A/ja active Granted
- 1981-10-02 KR KR1019810003721A patent/KR850001795B1/ko active
- 1981-10-02 CY CY135181A patent/CY1351A/xx unknown
- 1981-10-02 DE DE8181304572T patent/DE3171819D1/de not_active Expired
- 1981-10-02 GR GR66193A patent/GR75023B/el unknown
- 1981-10-03 EG EG566/81A patent/EG15678A/xx active
-
1982
- 1982-08-09 ES ES514868A patent/ES514868A0/es active Granted
- 1982-11-09 AR AR82291229A patent/AR241439A1/es active
-
1986
- 1986-11-25 MX MX572386A patent/MX5723A/es unknown
-
1987
- 1987-02-19 HK HK159/87A patent/HK15987A/xx not_active IP Right Cessation
- 1987-12-30 MY MY247/87A patent/MY8700247A/xx unknown
-
1991
- 1991-01-24 DK DK012391A patent/DK167759B1/da not_active IP Right Cessation
-
1993
- 1993-06-09 LU LU88293C patent/LU88293I2/fr unknown
- 1993-06-29 NL NL930107C patent/NL930107I2/nl unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8306135A1 (es) | "un procedimiento para la preparacion de un derivado de tiazol". | |
EP0478362A3 (en) | Fibrinogen receptor antagonists | |
GR3026277T3 (en) | Fibrinogen receptor antagonists | |
NZ214005A (en) | Benzimidazole derivatives and pharmaceutical compositions | |
GR3020715T3 (en) | Xanthine compounds | |
GR3019398T3 (en) | Substituted biphenylpyridinones as angiotensin II antagonists | |
AU580355B2 (en) | N-((4,6-dimethoxypyrimidin-2-YL)Aminocarbonyl)-3- trifluoromethylpridine-2-sulfonamide or salts thereof, herbicidal composition containing the same, and process for the production of the compound | |
DE69123286D1 (de) | Verwendung von 5-HT1A Rezeptoragonisten zur Hemmung der Magensäuresekretion | |
ES2007177A6 (es) | Procedimiento para preparar amidas y tioamidas del acido 1'-desoxi-1'-(6-amino-9-purinil)-b-d-ribofuranuronico sustituidas en la posicion 2. | |
IL62039A (en) | 2-(2-(1,4-benzodioxanyl))-2-imidazoline and non-toxic salts thereof,processes for the preparation thereof and pharmaceutical compositions containing them | |
EP0249328A3 (en) | Heterocyclic thione compounds and their use as biocides | |
EP0164040A3 (en) | Furan derivatives having anti-ulcer activity | |
EG18544A (en) | Six - membred heterocyclic derivatives of n', - substituted - n, n'-diacylhydrazines | |
DE3573114D1 (en) | 3-(2-aryl-2-oxoethyl)-imidazolium salts as hypoglycemic agents | |
ES2001389A6 (es) | Procedimiento para preparar derivados de o-toluidina | |
IL80360A0 (en) | 1,2,5-substituted imidazole compounds,processes for their preparation,and their use as growth regulators | |
ES8405386A1 (es) | Un procedimiento para la preparacion de un derivado de tiazol. | |
IE832456L (en) | 3-hydroxy-4-acylbenzene derivatives. | |
GR852772B (es) | ||
IT8748207A0 (it) | Composti eterociclici che agiscono su ricetori di 5-idrossitriptammina composizioni che li contengono eprocedimento per prepararli | |
NO831100L (no) | Substituerte 3,4-diamino-1,2,5-tiadiazoler med histamin h2-reseptorantagonistvirkning | |
ZA856671B (en) | N-substituted derivatives of 2-(pyridylaklenesulfinyl)benzimidazoles as gastric antisecretory agents | |
GB2055366B (en) | 2-phenylimino-5-(2'-carboxyphenyl)-1,3,4-thiadiazol-4-ine derivatives useful as plant-growth regulating agents | |
ES8505363A1 (es) | Un procedimiento para preparar una 3-(2-furoil)-5-2,6-dimetil-4-(2-nitrofenil)-1,4-dihidropiridina | |
NZ191383A (en) | N-(2-mercaptoethyl)-2-nitro -1, 1 - ethene di - amines |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20030225 |