NZ191383A - N-(2-mercaptoethyl)-2-nitro -1, 1 - ethene di - amines - Google Patents

N-(2-mercaptoethyl)-2-nitro -1, 1 - ethene di - amines

Info

Publication number
NZ191383A
NZ191383A NZ191383A NZ19138377A NZ191383A NZ 191383 A NZ191383 A NZ 191383A NZ 191383 A NZ191383 A NZ 191383A NZ 19138377 A NZ19138377 A NZ 19138377A NZ 191383 A NZ191383 A NZ 191383A
Authority
NZ
New Zealand
Prior art keywords
formula
aminoalkylfuran
mercaptoethyl
ethene
nitro
Prior art date
Application number
NZ191383A
Inventor
B J Price
J W Clitherow
J Bradshaw
Original Assignee
Allen & Hanburys Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27448487&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ191383(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB32465/76A external-priority patent/GB1565966A/en
Application filed by Allen & Hanburys Ltd filed Critical Allen & Hanburys Ltd
Priority claimed from KR7701808A external-priority patent/KR810000355B1/en
Publication of NZ191383A publication Critical patent/NZ191383A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D275/00Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/64Sulfur atoms

Abstract

Novel aminoalkylfuran derivatives of the general formula I: <IMAGE> in which the symbols have the meaning indicated in Claim 1, are prepared by reaction of a compound of the formula <IMAGE> with a compound of the formula R3NZZ'. A, B, Z and Z' have the meaning indicated in Claim 1. The aminoalkylfuran derivative can be used in the form of the free base or in the form of a physiologically acceptable salt or a hydrate. These novel aminoalkylfuran derivatives exhibit inhibition of gastric acid secretion if they are stimulated via histamine H2 receptors.
NZ191383A 1976-08-04 1977-07-27 N-(2-mercaptoethyl)-2-nitro -1, 1 - ethene di - amines NZ191383A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB32465/76A GB1565966A (en) 1976-08-04 1976-08-04 Aminoalkyl furan derivatives
GB5068576 1976-12-06
GB2018777 1977-05-13
KR7701808A KR810000355B1 (en) 1977-05-13 1977-08-04 Preparation for pharmacologically active compounds

Publications (1)

Publication Number Publication Date
NZ191383A true NZ191383A (en) 1980-09-12

Family

ID=27448487

Family Applications (2)

Application Number Title Priority Date Filing Date
NZ184759A NZ184759A (en) 1976-08-04 1977-07-27 Aminoalkyl-furan derivatives and pharmaceutical compositions
NZ191383A NZ191383A (en) 1976-08-04 1977-07-27 N-(2-mercaptoethyl)-2-nitro -1, 1 - ethene di - amines

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NZ184759A NZ184759A (en) 1976-08-04 1977-07-27 Aminoalkyl-furan derivatives and pharmaceutical compositions

Country Status (16)

Country Link
AT (1) AT375931B (en)
CH (2) CH642072A5 (en)
CY (1) CY1077A (en)
DE (2) DE2760097C2 (en)
DK (2) DK148258C (en)
ES (2) ES461334A1 (en)
FI (1) FI72318C (en)
HK (1) HK55780A (en)
IE (1) IE45456B1 (en)
IT (2) IT1126759B (en)
KE (1) KE3080A (en)
NZ (2) NZ184759A (en)
PH (1) PH13540A (en)
PT (1) PT66874B (en)
SE (3) SE437373B (en)
YU (2) YU40006B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4203909A (en) * 1978-09-26 1980-05-20 Bristol-Myers Company Furan compounds
YU52598A (en) * 1998-11-19 2001-05-28 D.D. Zdravlje- sektor za istraživanje i razvoj Procedure for synthesis of n-[2[[[5-[ (dialkylamino)methyl] -2-furanil]methyl]thi0]etyl]-n'-alkyl-2-nitro 1,1 alkendiamine and its hydrochloride

Also Published As

Publication number Publication date
HK55780A (en) 1980-10-10
DK416384D0 (en) 1984-08-30
NZ184759A (en) 1980-09-12
PH13540A (en) 1980-06-26
FI72318C (en) 1987-05-11
AT375931B (en) 1984-09-25
CH642072A5 (en) 1984-03-30
DK148258C (en) 1985-10-14
DK337977A (en) 1978-02-05
PT66874A (en) 1977-09-01
DK416384A (en) 1984-08-30
DK149952B (en) 1986-11-03
SE7708521L (en) 1978-02-05
SE454883B (en) 1988-06-06
CH641176A5 (en) 1984-02-15
YU40088B (en) 1985-06-30
IT1126759B (en) 1986-05-21
PT66874B (en) 1979-01-23
CY1077A (en) 1980-12-27
DK148258B (en) 1985-05-20
ATA574077A (en) 1984-02-15
IT1221058B (en) 1990-06-21
SE454882B (en) 1988-06-06
ES470836A1 (en) 1979-02-16
ES461334A1 (en) 1979-05-16
SE8205533D0 (en) 1982-09-28
YU200082A (en) 1983-01-21
DE2759959C2 (en) 1988-08-04
DK149952C (en) 1987-07-06
SE437373B (en) 1985-02-25
FI72318B (en) 1987-01-30
IT8548437A0 (en) 1985-08-01
KE3080A (en) 1980-10-03
IE45456B1 (en) 1982-08-25
DE2760097C2 (en) 1989-08-17
FI772264A (en) 1978-02-05
SE8205533L (en) 1982-09-28
YU191177A (en) 1983-01-21
IE45456L (en) 1978-02-04
SE8206556L (en) 1982-11-17
SE8206556D0 (en) 1982-11-17
YU40006B (en) 1985-06-30

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