IT1126759B - AMINO ALKYLFURANIC DERIVATIVE, PROCEDURES FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT - Google Patents

AMINO ALKYLFURANIC DERIVATIVE, PROCEDURES FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT

Info

Publication number
IT1126759B
IT1126759B IT50551/77A IT5055177A IT1126759B IT 1126759 B IT1126759 B IT 1126759B IT 50551/77 A IT50551/77 A IT 50551/77A IT 5055177 A IT5055177 A IT 5055177A IT 1126759 B IT1126759 B IT 1126759B
Authority
IT
Italy
Prior art keywords
derivative
alkylfuranic
procedures
amino
preparation
Prior art date
Application number
IT50551/77A
Other languages
Italian (it)
Original Assignee
Allen & Hanburys Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27448487&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1126759(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB32465/76A external-priority patent/GB1565966A/en
Application filed by Allen & Hanburys Ltd filed Critical Allen & Hanburys Ltd
Priority claimed from KR7701808A external-priority patent/KR810000355B1/en
Application granted granted Critical
Publication of IT1126759B publication Critical patent/IT1126759B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/64—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Novel aminoalkylfuran derivatives of the general formula I: <IMAGE> in which the symbols have the meaning indicated in Claim 1, are prepared by reaction of a compound of the formula <IMAGE> with a compound of the formula R3NZZ'. A, B, Z and Z' have the meaning indicated in Claim 1. The aminoalkylfuran derivative can be used in the form of the free base or in the form of a physiologically acceptable salt or a hydrate. These novel aminoalkylfuran derivatives exhibit inhibition of gastric acid secretion if they are stimulated via histamine H2 receptors.
IT50551/77A 1976-08-04 1977-08-03 AMINO ALKYLFURANIC DERIVATIVE, PROCEDURES FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT IT1126759B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB32465/76A GB1565966A (en) 1976-08-04 1976-08-04 Aminoalkyl furan derivatives
GB5068576 1976-12-06
GB2018777 1977-05-13
KR7701808A KR810000355B1 (en) 1977-05-13 1977-08-04 Preparation for pharmacologically active compounds

Publications (1)

Publication Number Publication Date
IT1126759B true IT1126759B (en) 1986-05-21

Family

ID=27448487

Family Applications (2)

Application Number Title Priority Date Filing Date
IT50551/77A IT1126759B (en) 1976-08-04 1977-08-03 AMINO ALKYLFURANIC DERIVATIVE, PROCEDURES FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT
IT48437/85A IT1221058B (en) 1976-08-04 1985-08-01 AMINE COMPOUNDS AS INTERMEDIATES IN THE PRODUCTION OF SELECTIVE AGENTS ON HISTAMINE RECEPTORS AND PROCEDURES FOR THE PRODUCTION OF THESE AMINE COMPOUNDS

Family Applications After (1)

Application Number Title Priority Date Filing Date
IT48437/85A IT1221058B (en) 1976-08-04 1985-08-01 AMINE COMPOUNDS AS INTERMEDIATES IN THE PRODUCTION OF SELECTIVE AGENTS ON HISTAMINE RECEPTORS AND PROCEDURES FOR THE PRODUCTION OF THESE AMINE COMPOUNDS

Country Status (16)

Country Link
AT (1) AT375931B (en)
CH (2) CH642072A5 (en)
CY (1) CY1077A (en)
DE (2) DE2759959C2 (en)
DK (2) DK148258C (en)
ES (2) ES461334A1 (en)
FI (1) FI72318C (en)
HK (1) HK55780A (en)
IE (1) IE45456B1 (en)
IT (2) IT1126759B (en)
KE (1) KE3080A (en)
NZ (2) NZ184759A (en)
PH (1) PH13540A (en)
PT (1) PT66874B (en)
SE (3) SE437373B (en)
YU (2) YU40006B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4203909A (en) * 1978-09-26 1980-05-20 Bristol-Myers Company Furan compounds
YU52598A (en) * 1998-11-19 2001-05-28 D.D. Zdravlje- sektor za istraživanje i razvoj Procedure for synthesis of n-[2[[[5-[ (dialkylamino)methyl] -2-furanil]methyl]thi0]etyl]-n'-alkyl-2-nitro 1,1 alkendiamine and its hydrochloride

Also Published As

Publication number Publication date
SE7708521L (en) 1978-02-05
CY1077A (en) 1980-12-27
PT66874B (en) 1979-01-23
CH642072A5 (en) 1984-03-30
SE8205533D0 (en) 1982-09-28
DK149952B (en) 1986-11-03
IE45456L (en) 1978-02-04
FI72318C (en) 1987-05-11
PT66874A (en) 1977-09-01
DK149952C (en) 1987-07-06
SE8206556L (en) 1982-11-17
ES461334A1 (en) 1979-05-16
KE3080A (en) 1980-10-03
SE454883B (en) 1988-06-06
SE454882B (en) 1988-06-06
IT1221058B (en) 1990-06-21
NZ191383A (en) 1980-09-12
DK416384D0 (en) 1984-08-30
DE2759959C2 (en) 1988-08-04
ATA574077A (en) 1984-02-15
DK148258B (en) 1985-05-20
YU191177A (en) 1983-01-21
DK148258C (en) 1985-10-14
DK416384A (en) 1984-08-30
AT375931B (en) 1984-09-25
SE8206556D0 (en) 1982-11-17
YU200082A (en) 1983-01-21
FI772264A (en) 1978-02-05
IT8548437A0 (en) 1985-08-01
ES470836A1 (en) 1979-02-16
FI72318B (en) 1987-01-30
YU40088B (en) 1985-06-30
YU40006B (en) 1985-06-30
DE2760097C2 (en) 1989-08-17
SE8205533L (en) 1982-09-28
CH641176A5 (en) 1984-02-15
PH13540A (en) 1980-06-26
NZ184759A (en) 1980-09-12
SE437373B (en) 1985-02-25
HK55780A (en) 1980-10-10
DK337977A (en) 1978-02-05
IE45456B1 (en) 1982-08-25

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Legal Events

Date Code Title Description
ITCP Complementary protection certificate

Free format text: CCP 212

MEDD Supplementary protection certificate for pharmaceutical products: granted

Free format text: CCP 212, 19920504; ALLEN & HANBURYS LIMITED

TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960830