SE8206556L - INTERMEDIATE - Google Patents

INTERMEDIATE

Info

Publication number
SE8206556L
SE8206556L SE8206556A SE8206556A SE8206556L SE 8206556 L SE8206556 L SE 8206556L SE 8206556 A SE8206556 A SE 8206556A SE 8206556 A SE8206556 A SE 8206556A SE 8206556 L SE8206556 L SE 8206556L
Authority
SE
Sweden
Prior art keywords
group
lower alkyl
1agalkyl
oxygen atom
hydrogen atom
Prior art date
Application number
SE8206556A
Other languages
Swedish (sv)
Other versions
SE454883B (en
SE8206556D0 (en
Inventor
B J Price
J W Clitherow
J Bradshaw
Original Assignee
Allen & Hanburys Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27448487&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE8206556(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB32465/76A external-priority patent/GB1565966A/en
Priority claimed from KR7701808A external-priority patent/KR810000355B1/en
Application filed by Allen & Hanburys Ltd filed Critical Allen & Hanburys Ltd
Publication of SE8206556L publication Critical patent/SE8206556L/en
Publication of SE8206556D0 publication Critical patent/SE8206556D0/en
Publication of SE454883B publication Critical patent/SE454883B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/64—Sulfur atoms

Claims (2)

PatentkravPatent claims 1. Mellanprcdukt till anvandning vid framstallning am foreningar med den allmAnna formelnIntermediate for use in the preparation of compounds of the general formula 2. -Ilk(CH2)nX(CH)mNHCIAIR(I) 22 dar Ri, 22, Ilk, n, X och m ham de nedan angivna betydelserna, dRr 23 betecknar en vateatom, en lAgalkylgrupp, en lAgalkenylgrupp eller en alkoxialkylgrupp, och dgr Y betecknar =2, =0, =22 eller =CHR6, clAr 2 betecknar en vateatom, en nitrogrupp, en cyangrupp, en lagalkylgrupp, en arylgrupp, en alkylsulfonylgrupp eller en arylsulfonylgrupp och 26 betecknar en nitrogrupp, en arylsulfonylgrupp eller en alkylsulfonylgrupp,kRnnetecknad am alt den bar den all-manna formeln dar Ri betecknar en vateatom, en lagalkylgrupp, en cykloalkylgrupp, en lagalkenylgrupp, en aralkylgrupp eller en lagalkylgrupp avbruten am en syreatom eller en grupp -N-, dRr HI betecknar vate eller lag- alkyl; dgr 22 betecknar en lAgalkylgrupp, en cykloalkylgrupp, en lagalkenylgrupp, en aralkylgrupp eller en lAgalkylgrupp avbruten am en syreatom eller en grupp -N-; eller RI dar symbolerna Ri och 22 tillsammans med den kvaveatom, till vilken de In bundna, bildar en hterocyklisk ring, vilken dessutom kan innehalla en syreatom eller en grupp -N-; dn. X betecknar 0112, 0 eller 2; dAr A4 Ilk betecknar en rat eller forgrenad alkylenkedja innehAllande 1-6 kolatomer; dar m betecknar ett heltal film 2 till 4; och dar n betecknar 1 eller 2, eller dAr in betecknar 0, 1 eller 2 ngr I betecknar S eller CH2; saint skyddade derivat darav. (M2)11.0A22. -Ik (CH2) nX (CH) mNHCIAIR (I) 22 gives Ri, 22, Ilk, n, X and m have the meanings given below, dRr 23 represents a hydrogen atom, a 1Agalkyl group, an 1Agalkenyl group or an alkoxyalkyl group, and dgr Y represents = 2, = 0, = 22 or = CHR 6, clAr 2 represents a hydrogen atom, a nitro group, a cyano group, a lower alkyl group, an aryl group, an alkylsulfonyl group or an arylsulfonyl group and 26 represents a nitro group, an arylsulfonyl group or an alkylsulfonyl group, denoted by the general formula wherein R 1 represents a hydrogen atom, a lower alkyl group, a cycloalkyl group, a lower alkenyl group, an aralkyl group or a lower alkyl group interrupted by an oxygen atom or a group -N-, where H 1 represents hydrogen or lower alkyl; dgr 22 denotes a 1Agalkyl group, a cycloalkyl group, a lagalkenyl group, an aralkyl group or a 1Agalkyl group interrupted by an oxygen atom or a group -N-; or R 1 where the symbols R 1 and 22 together with the nitrogen atom to which they are attached form a heterocyclic ring, which may additionally contain an oxygen atom or a group -N-; dn. X represents 0112, 0 or 2; dAr A4 Ilk represents a straight or branched alkylene chain containing 1-6 carbon atoms; where m represents an integer film 2 to 4; and where n represents 1 or 2, or dAr in represents 0, 1 or 2 ngr I represents S or CH 2; saint protected derivatives thereof. (M2) 11.0A2
SE8206556A 1976-08-04 1982-11-17 AMINOALKYL REFERENCE DERIVATIVES FOR USING INTERMEDIATES IN THE PREPARATION OF AMINOALKYL REFERENCE DERIVATIVES WITH THERAPEUTIC EFFECT SE454883B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB32465/76A GB1565966A (en) 1976-08-04 1976-08-04 Aminoalkyl furan derivatives
GB5068576 1976-12-06
GB2018777 1977-05-13
KR7701808A KR810000355B1 (en) 1977-05-13 1977-08-04 Preparation for pharmacologically active compounds

Publications (3)

Publication Number Publication Date
SE8206556L true SE8206556L (en) 1982-11-17
SE8206556D0 SE8206556D0 (en) 1982-11-17
SE454883B SE454883B (en) 1988-06-06

Family

ID=27448487

Family Applications (3)

Application Number Title Priority Date Filing Date
SE7708521A SE437373B (en) 1976-08-04 1977-07-25 PROCEDURE FOR PREPARING AN AMINOAL COOLING RANGE DERIVATIVE WITH THERAPEUTIC EFFECT
SE8205533A SE454882B (en) 1976-08-04 1982-09-28 PROCEDURE FOR THE PREPARATION OF AMINOAL COOLING RANGE DERIVATIVES WITH THERAPEUTIC EFFECT
SE8206556A SE454883B (en) 1976-08-04 1982-11-17 AMINOALKYL REFERENCE DERIVATIVES FOR USING INTERMEDIATES IN THE PREPARATION OF AMINOALKYL REFERENCE DERIVATIVES WITH THERAPEUTIC EFFECT

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SE7708521A SE437373B (en) 1976-08-04 1977-07-25 PROCEDURE FOR PREPARING AN AMINOAL COOLING RANGE DERIVATIVE WITH THERAPEUTIC EFFECT
SE8205533A SE454882B (en) 1976-08-04 1982-09-28 PROCEDURE FOR THE PREPARATION OF AMINOAL COOLING RANGE DERIVATIVES WITH THERAPEUTIC EFFECT

Country Status (16)

Country Link
AT (1) AT375931B (en)
CH (2) CH642072A5 (en)
CY (1) CY1077A (en)
DE (2) DE2760097C2 (en)
DK (2) DK148258C (en)
ES (2) ES461334A1 (en)
FI (1) FI72318C (en)
HK (1) HK55780A (en)
IE (1) IE45456B1 (en)
IT (2) IT1126759B (en)
KE (1) KE3080A (en)
NZ (2) NZ184759A (en)
PH (1) PH13540A (en)
PT (1) PT66874B (en)
SE (3) SE437373B (en)
YU (2) YU40006B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4203909A (en) * 1978-09-26 1980-05-20 Bristol-Myers Company Furan compounds
YU52598A (en) * 1998-11-19 2001-05-28 D.D. Zdravlje- sektor za istraživanje i razvoj Procedure for synthesis of n-[2[[[5-[ (dialkylamino)methyl] -2-furanil]methyl]thi0]etyl]-n'-alkyl-2-nitro 1,1 alkendiamine and its hydrochloride

Also Published As

Publication number Publication date
HK55780A (en) 1980-10-10
DK416384D0 (en) 1984-08-30
NZ184759A (en) 1980-09-12
PH13540A (en) 1980-06-26
FI72318C (en) 1987-05-11
AT375931B (en) 1984-09-25
CH642072A5 (en) 1984-03-30
DK148258C (en) 1985-10-14
DK337977A (en) 1978-02-05
PT66874A (en) 1977-09-01
DK416384A (en) 1984-08-30
DK149952B (en) 1986-11-03
SE7708521L (en) 1978-02-05
SE454883B (en) 1988-06-06
CH641176A5 (en) 1984-02-15
YU40088B (en) 1985-06-30
IT1126759B (en) 1986-05-21
NZ191383A (en) 1980-09-12
PT66874B (en) 1979-01-23
CY1077A (en) 1980-12-27
DK148258B (en) 1985-05-20
ATA574077A (en) 1984-02-15
IT1221058B (en) 1990-06-21
SE454882B (en) 1988-06-06
ES470836A1 (en) 1979-02-16
ES461334A1 (en) 1979-05-16
SE8205533D0 (en) 1982-09-28
YU200082A (en) 1983-01-21
DE2759959C2 (en) 1988-08-04
DK149952C (en) 1987-07-06
SE437373B (en) 1985-02-25
FI72318B (en) 1987-01-30
IT8548437A0 (en) 1985-08-01
KE3080A (en) 1980-10-03
IE45456B1 (en) 1982-08-25
DE2760097C2 (en) 1989-08-17
FI772264A (en) 1978-02-05
SE8205533L (en) 1982-09-28
YU191177A (en) 1983-01-21
IE45456L (en) 1978-02-04
SE8206556D0 (en) 1982-11-17
YU40006B (en) 1985-06-30

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