IE42390L - Substituted indoles. - Google Patents
Substituted indoles.Info
- Publication number
- IE42390L IE42390L IE752830A IE283075A IE42390L IE 42390 L IE42390 L IE 42390L IE 752830 A IE752830 A IE 752830A IE 283075 A IE283075 A IE 283075A IE 42390 L IE42390 L IE 42390L
- Authority
- IE
- Ireland
- Prior art keywords
- substituted indoles
- group
- formula
- image
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
Novel substituted indoles containing a thio group, of the formula I <IMAGE> or of the formula I' <IMAGE> are prepared by introducing the heterocyclic groups indicated into the corresponding amines by substitution on the nitrogen atom. In the substituted indoles of the formulae I and I', the substituents have the meaning given in Patent Claim 1 and the thio group of these compounds can be converted into the sulphonyl group or sulphinyl group by oxidation. All these novel compounds have the effect of decreasing the heart rate.
[GB1527510A]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53761274A | 1974-12-30 | 1974-12-30 | |
US63179875A | 1975-11-13 | 1975-11-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
IE42390L true IE42390L (en) | 1976-06-30 |
IE42390B1 IE42390B1 (en) | 1980-07-30 |
Family
ID=27065555
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE2830/75A IE42390B1 (en) | 1974-12-30 | 1975-12-30 | Substituted indoles and precursors therefor |
Country Status (27)
Country | Link |
---|---|
JP (1) | JPS51131872A (en) |
AR (1) | AR219052A1 (en) |
AT (1) | AT356648B (en) |
AU (1) | AU505215B2 (en) |
CA (1) | CA1065874A (en) |
CH (1) | CH622516A5 (en) |
DD (1) | DD125781A5 (en) |
DE (1) | DE2559211A1 (en) |
DK (1) | DK580175A (en) |
ES (1) | ES443935A1 (en) |
FI (1) | FI64590C (en) |
FR (2) | FR2296413A1 (en) |
GB (1) | GB1527510A (en) |
HU (2) | HU174949B (en) |
IE (1) | IE42390B1 (en) |
IL (1) | IL48756A (en) |
IN (1) | IN142735B (en) |
IT (1) | IT1052654B (en) |
NL (1) | NL7515100A (en) |
NO (1) | NO145383C (en) |
NZ (1) | NZ179580A (en) |
PH (1) | PH12328A (en) |
PL (1) | PL99353B1 (en) |
RO (1) | RO69196A (en) |
SE (1) | SE422210B (en) |
SU (1) | SU667132A3 (en) |
YU (1) | YU332275A (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1595056A (en) * | 1976-10-12 | 1981-08-05 | Wellcome Found | Pharmaceutical combination |
FR2540109B1 (en) * | 1983-01-28 | 1985-08-30 | Logeais Labor Jacques | IMINO-2 PYRROLIDINES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATIONS |
US4558048A (en) * | 1984-04-06 | 1985-12-10 | Pfizer Inc. | Method of treating diarrhoea using indole compounds |
US6639109B1 (en) | 1999-09-28 | 2003-10-28 | Nihon Nohyaku Co., Ltd. | Process for production of thioalkylamine derivatives |
UA79504C2 (en) * | 2002-11-07 | 2007-06-25 | Organon Nv | Indols for treating diseases associated with androgen receptors |
DE60332769D1 (en) | 2002-11-07 | 2010-07-08 | Organon Nv | INDOLE FOR TREATING DISEASES RELATED TO THE ANDROGEN RECEPTOR |
TW200602317A (en) | 2004-04-23 | 2006-01-16 | Akzo Nobel Nv | Novel androgens |
WO2007020653A1 (en) * | 2005-08-12 | 2007-02-22 | Suven Life Sciences Limited | Thioether derivatives as functional 5-ht6 ligands |
-
1975
- 1975-12-17 NZ NZ179580A patent/NZ179580A/en unknown
- 1975-12-17 IN IN2354/CAL/75A patent/IN142735B/en unknown
- 1975-12-18 NO NO754313A patent/NO145383C/en unknown
- 1975-12-19 DK DK580175A patent/DK580175A/en not_active Application Discontinuation
- 1975-12-19 SE SE7514458A patent/SE422210B/en unknown
- 1975-12-24 CH CH1679775A patent/CH622516A5/en not_active IP Right Cessation
- 1975-12-24 NL NL7515100A patent/NL7515100A/en not_active Application Discontinuation
- 1975-12-26 JP JP50155154A patent/JPS51131872A/en active Pending
- 1975-12-29 FI FI753669A patent/FI64590C/en not_active IP Right Cessation
- 1975-12-29 PH PH7517930A patent/PH12328A/en unknown
- 1975-12-29 GB GB53024/75A patent/GB1527510A/en not_active Expired
- 1975-12-29 YU YU03322/75A patent/YU332275A/en unknown
- 1975-12-29 RO RO7584353A patent/RO69196A/en unknown
- 1975-12-29 AT AT986075A patent/AT356648B/en not_active IP Right Cessation
- 1975-12-29 DD DD190619A patent/DD125781A5/xx unknown
- 1975-12-29 IL IL48756A patent/IL48756A/en unknown
- 1975-12-29 CA CA242,669A patent/CA1065874A/en not_active Expired
- 1975-12-29 IT IT7552899A patent/IT1052654B/en active
- 1975-12-29 ES ES443935A patent/ES443935A1/en not_active Expired
- 1975-12-30 PL PL1975186097A patent/PL99353B1/en unknown
- 1975-12-30 FR FR7540132A patent/FR2296413A1/en active Granted
- 1975-12-30 AR AR261797A patent/AR219052A1/en active
- 1975-12-30 DE DE19752559211 patent/DE2559211A1/en not_active Ceased
- 1975-12-30 SU SU752307502A patent/SU667132A3/en active
- 1975-12-30 HU HU75ME2020A patent/HU174949B/en unknown
- 1975-12-30 IE IE2830/75A patent/IE42390B1/en unknown
- 1975-12-30 AU AU87916/75A patent/AU505215B2/en not_active Expired
- 1975-12-30 HU HU75ME1936A patent/HU174948B/en unknown
-
1976
- 1976-08-30 FR FR7626153A patent/FR2315921A1/en active Granted
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