ES8405386A1 - Un procedimiento para la preparacion de un derivado de tiazol. - Google Patents
Un procedimiento para la preparacion de un derivado de tiazol.Info
- Publication number
- ES8405386A1 ES8405386A1 ES520791A ES520791A ES8405386A1 ES 8405386 A1 ES8405386 A1 ES 8405386A1 ES 520791 A ES520791 A ES 520791A ES 520791 A ES520791 A ES 520791A ES 8405386 A1 ES8405386 A1 ES 8405386A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- thiazole derivatives
- ethenediamines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/194—Radicals derived from thio- or thiono carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Fats And Perfumes (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Supply Devices, Intensifiers, Converters, And Telemotors (AREA)
- Earth Drilling (AREA)
- Inert Electrodes (AREA)
- Treating Waste Gases (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE UN DERIVADO DE TIAZOL, DE FORMULA (I), EN LA QUE R Y R SON HIDROGENO O ALQUILO C1-C4; R ES HIDROGENO O ALQUILO C1-C3; Z ES O, S O CH2; N ES 2 O 3; M ES 1, 2 O 3; R ES H O CH3; A ES N-CN, CH-NO2, S, O O NH; R ES ALQUILENO O ALQUINILO; Y R Y R SON H, CH3 O C2H5 Y SUS SALES FARMACEUTICAMENTE ACEPTABLES.CONSISTE EN HACER REACCIONAR UNA AMINA DE FORMULA (II) CON UN COMPUESTO DE FORMULA (I), EN LAS QUE W ES UN RADICAL; Y LOS RESTANTES SIMBOLOS TIENEN LOS SIGNIFICADOS YA MENCIONADOS.DE APLICACION EN EL TRATAMIENTO DE ULCERASPEPTICAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/360,034 US4474794A (en) | 1982-03-19 | 1982-03-19 | N-Thiazolylmethylthioalkyl-N1 -alkenyl (or alkynyl)guanidines and related compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8405386A1 true ES8405386A1 (es) | 1984-06-01 |
| ES520791A0 ES520791A0 (es) | 1984-06-01 |
Family
ID=23416322
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES520791A Granted ES520791A0 (es) | 1982-03-19 | 1983-03-18 | Un procedimiento para la preparacion de un derivado de tiazol. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4474794A (es) |
| EP (1) | EP0091220B1 (es) |
| JP (1) | JPS58170773A (es) |
| KR (1) | KR840004091A (es) |
| AT (1) | ATE27156T1 (es) |
| AU (1) | AU1254583A (es) |
| CA (1) | CA1190547A (es) |
| CS (1) | CS236788B2 (es) |
| DD (1) | DD207376A5 (es) |
| DE (1) | DE3371514D1 (es) |
| DK (1) | DK91083A (es) |
| ES (1) | ES520791A0 (es) |
| FI (1) | FI830879L (es) |
| GB (1) | GB2116973B (es) |
| GR (1) | GR77882B (es) |
| IL (1) | IL68152A0 (es) |
| NZ (1) | NZ203605A (es) |
| PH (1) | PH18504A (es) |
| PL (1) | PL241066A1 (es) |
| PT (1) | PT76397B (es) |
| RO (1) | RO85385B (es) |
| ZA (1) | ZA831882B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1277325C (en) * | 1985-12-18 | 1990-12-04 | Bruce A. Slomski | Synthesis of nizatidine |
| ATE86619T1 (de) * | 1987-04-06 | 1993-03-15 | Heumann Pharma Gmbh & Co | Verfahren zur herstellung von nitroethenderivaten. |
| NL9000132A (nl) * | 1990-01-19 | 1991-08-16 | Cedona Pharm Bv | Nieuwe thiazoolderivaten. |
| US20230349922A1 (en) | 2020-08-11 | 2023-11-02 | Université De Strasbourg | H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4200578A (en) * | 1978-12-18 | 1980-04-29 | Bristol-Myers Company | Thiazole derivatives |
| US4375547A (en) * | 1980-10-02 | 1983-03-01 | Eli Lilly And Company | N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine |
-
1982
- 1982-03-19 US US06/360,034 patent/US4474794A/en not_active Expired - Fee Related
-
1983
- 1983-02-25 DK DK91083A patent/DK91083A/da not_active Application Discontinuation
- 1983-03-16 DE DE8383301461T patent/DE3371514D1/de not_active Expired
- 1983-03-16 GR GR70814A patent/GR77882B/el unknown
- 1983-03-16 GB GB08307201A patent/GB2116973B/en not_active Expired
- 1983-03-16 EP EP83301461A patent/EP0091220B1/en not_active Expired
- 1983-03-16 PT PT76397A patent/PT76397B/pt unknown
- 1983-03-16 CA CA000423708A patent/CA1190547A/en not_active Expired
- 1983-03-16 AT AT83301461T patent/ATE27156T1/de not_active IP Right Cessation
- 1983-03-16 RO RO110351A patent/RO85385B/ro unknown
- 1983-03-16 FI FI830879A patent/FI830879L/fi not_active Application Discontinuation
- 1983-03-16 IL IL68152A patent/IL68152A0/xx unknown
- 1983-03-17 ZA ZA831882A patent/ZA831882B/xx unknown
- 1983-03-17 DD DD83248911A patent/DD207376A5/de unknown
- 1983-03-17 PH PH28661A patent/PH18504A/en unknown
- 1983-03-17 KR KR1019830001082A patent/KR840004091A/ko not_active IP Right Cessation
- 1983-03-17 NZ NZ203605A patent/NZ203605A/en unknown
- 1983-03-17 PL PL24106683A patent/PL241066A1/xx unknown
- 1983-03-17 JP JP58047005A patent/JPS58170773A/ja active Pending
- 1983-03-17 AU AU12545/83A patent/AU1254583A/en not_active Abandoned
- 1983-03-18 ES ES520791A patent/ES520791A0/es active Granted
-
1984
- 1984-03-16 CS CS831821A patent/CS236788B2/cs unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL241066A1 (en) | 1985-01-02 |
| EP0091220A2 (en) | 1983-10-12 |
| GB2116973B (en) | 1985-08-29 |
| IL68152A0 (en) | 1983-06-15 |
| AU1254583A (en) | 1983-09-22 |
| KR840004091A (ko) | 1984-10-06 |
| GB2116973A (en) | 1983-10-05 |
| CA1190547A (en) | 1985-07-16 |
| JPS58170773A (ja) | 1983-10-07 |
| FI830879L (fi) | 1983-09-20 |
| DK91083D0 (da) | 1983-02-25 |
| ATE27156T1 (de) | 1987-05-15 |
| PT76397A (en) | 1983-04-01 |
| PT76397B (en) | 1986-02-04 |
| FI830879A0 (fi) | 1983-03-16 |
| ZA831882B (en) | 1984-11-28 |
| EP0091220B1 (en) | 1987-05-13 |
| PH18504A (en) | 1985-08-02 |
| DD207376A5 (de) | 1984-02-29 |
| EP0091220A3 (en) | 1984-05-23 |
| DK91083A (da) | 1983-09-20 |
| CS236788B2 (en) | 1985-05-15 |
| GR77882B (es) | 1984-09-25 |
| RO85385A (ro) | 1984-11-25 |
| GB8307201D0 (en) | 1983-04-20 |
| NZ203605A (en) | 1985-10-11 |
| DE3371514D1 (en) | 1987-06-19 |
| US4474794A (en) | 1984-10-02 |
| RO85385B (ro) | 1984-11-30 |
| ES520791A0 (es) | 1984-06-01 |
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