DK91083A - Fremgangsmaade til fremstilling af thiazol-derivater - Google Patents

Fremgangsmaade til fremstilling af thiazol-derivater Download PDF

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Publication number
DK91083A
DK91083A DK91083A DK91083A DK91083A DK 91083 A DK91083 A DK 91083A DK 91083 A DK91083 A DK 91083A DK 91083 A DK91083 A DK 91083A DK 91083 A DK91083 A DK 91083A
Authority
DK
Denmark
Prior art keywords
sub
sup
alkyl
aryl
alkynyl
Prior art date
Application number
DK91083A
Other languages
English (en)
Other versions
DK91083D0 (da
Inventor
Richard Paul Pioch
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK91083D0 publication Critical patent/DK91083D0/da
Publication of DK91083A publication Critical patent/DK91083A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/194Radicals derived from thio- or thiono carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Supply Devices, Intensifiers, Converters, And Telemotors (AREA)
  • Earth Drilling (AREA)
  • Inert Electrodes (AREA)
  • Treating Waste Gases (AREA)
DK91083A 1982-03-19 1983-02-25 Fremgangsmaade til fremstilling af thiazol-derivater DK91083A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/360,034 US4474794A (en) 1982-03-19 1982-03-19 N-Thiazolylmethylthioalkyl-N1 -alkenyl (or alkynyl)guanidines and related compounds

Publications (2)

Publication Number Publication Date
DK91083D0 DK91083D0 (da) 1983-02-25
DK91083A true DK91083A (da) 1983-09-20

Family

ID=23416322

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91083A DK91083A (da) 1982-03-19 1983-02-25 Fremgangsmaade til fremstilling af thiazol-derivater

Country Status (22)

Country Link
US (1) US4474794A (da)
EP (1) EP0091220B1 (da)
JP (1) JPS58170773A (da)
KR (1) KR840004091A (da)
AT (1) ATE27156T1 (da)
AU (1) AU1254583A (da)
CA (1) CA1190547A (da)
CS (1) CS236788B2 (da)
DD (1) DD207376A5 (da)
DE (1) DE3371514D1 (da)
DK (1) DK91083A (da)
ES (1) ES520791A0 (da)
FI (1) FI830879L (da)
GB (1) GB2116973B (da)
GR (1) GR77882B (da)
IL (1) IL68152A0 (da)
NZ (1) NZ203605A (da)
PH (1) PH18504A (da)
PL (1) PL241066A1 (da)
PT (1) PT76397B (da)
RO (1) RO85385B (da)
ZA (1) ZA831882B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1277325C (en) * 1985-12-18 1990-12-04 Bruce A. Slomski Synthesis of nizatidine
ATE86619T1 (de) * 1987-04-06 1993-03-15 Heumann Pharma Gmbh & Co Verfahren zur herstellung von nitroethenderivaten.
NL9000132A (nl) * 1990-01-19 1991-08-16 Cedona Pharm Bv Nieuwe thiazoolderivaten.
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200578A (en) * 1978-12-18 1980-04-29 Bristol-Myers Company Thiazole derivatives
US4375547A (en) * 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine

Also Published As

Publication number Publication date
PL241066A1 (en) 1985-01-02
EP0091220A2 (en) 1983-10-12
GB2116973B (en) 1985-08-29
IL68152A0 (en) 1983-06-15
AU1254583A (en) 1983-09-22
KR840004091A (ko) 1984-10-06
GB2116973A (en) 1983-10-05
CA1190547A (en) 1985-07-16
JPS58170773A (ja) 1983-10-07
FI830879L (fi) 1983-09-20
DK91083D0 (da) 1983-02-25
ATE27156T1 (de) 1987-05-15
PT76397A (en) 1983-04-01
PT76397B (en) 1986-02-04
FI830879A0 (fi) 1983-03-16
ZA831882B (en) 1984-11-28
EP0091220B1 (en) 1987-05-13
ES8405386A1 (es) 1984-06-01
PH18504A (en) 1985-08-02
DD207376A5 (de) 1984-02-29
EP0091220A3 (en) 1984-05-23
CS236788B2 (en) 1985-05-15
GR77882B (da) 1984-09-25
RO85385A (ro) 1984-11-25
GB8307201D0 (en) 1983-04-20
NZ203605A (en) 1985-10-11
DE3371514D1 (en) 1987-06-19
US4474794A (en) 1984-10-02
RO85385B (ro) 1984-11-30
ES520791A0 (es) 1984-06-01

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