RO85385A - Procedeu pentru prepararea unor derivati de tiazol - Google Patents

Procedeu pentru prepararea unor derivati de tiazol

Info

Publication number
RO85385A
RO85385A RO83110351A RO11035183A RO85385A RO 85385 A RO85385 A RO 85385A RO 83110351 A RO83110351 A RO 83110351A RO 11035183 A RO11035183 A RO 11035183A RO 85385 A RO85385 A RO 85385A
Authority
RO
Romania
Prior art keywords
sub
sup
alkyl
aryl
alkynyl
Prior art date
Application number
RO83110351A
Other languages
English (en)
French (fr)
Other versions
RO85385B (ro
Inventor
Richard P Pioch
Original Assignee
Eli Lilly And Co,Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Co,Us filed Critical Eli Lilly And Co,Us
Publication of RO85385A publication Critical patent/RO85385A/ro
Publication of RO85385B publication Critical patent/RO85385B/ro

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/194Radicals derived from thio- or thiono carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
RO110351A 1982-03-19 1983-03-16 Procedeu pentru prepararea unor derivati de tiazol RO85385B (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/360,034 US4474794A (en) 1982-03-19 1982-03-19 N-Thiazolylmethylthioalkyl-N1 -alkenyl (or alkynyl)guanidines and related compounds

Publications (2)

Publication Number Publication Date
RO85385A true RO85385A (ro) 1984-11-25
RO85385B RO85385B (ro) 1984-11-30

Family

ID=23416322

Family Applications (1)

Application Number Title Priority Date Filing Date
RO110351A RO85385B (ro) 1982-03-19 1983-03-16 Procedeu pentru prepararea unor derivati de tiazol

Country Status (22)

Country Link
US (1) US4474794A (ro)
EP (1) EP0091220B1 (ro)
JP (1) JPS58170773A (ro)
KR (1) KR840004091A (ro)
AT (1) ATE27156T1 (ro)
AU (1) AU1254583A (ro)
CA (1) CA1190547A (ro)
CS (1) CS236788B2 (ro)
DD (1) DD207376A5 (ro)
DE (1) DE3371514D1 (ro)
DK (1) DK91083A (ro)
ES (1) ES520791A0 (ro)
FI (1) FI830879L (ro)
GB (1) GB2116973B (ro)
GR (1) GR77882B (ro)
IL (1) IL68152A0 (ro)
NZ (1) NZ203605A (ro)
PH (1) PH18504A (ro)
PL (1) PL241066A1 (ro)
PT (1) PT76397B (ro)
RO (1) RO85385B (ro)
ZA (1) ZA831882B (ro)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL80961A0 (en) * 1985-12-18 1987-03-31 Lilly Co Eli Synthesis of nizatidine
ES2053462T3 (es) * 1987-04-06 1994-08-01 Heumann Pharma Gmbh & Co Procedimiento para la produccion de derivados de nitroetano.
NL9000132A (nl) * 1990-01-19 1991-08-16 Cedona Pharm Bv Nieuwe thiazoolderivaten.
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200578A (en) * 1978-12-18 1980-04-29 Bristol-Myers Company Thiazole derivatives
US4375547A (en) * 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine

Also Published As

Publication number Publication date
DK91083A (da) 1983-09-20
GB2116973B (en) 1985-08-29
PL241066A1 (en) 1985-01-02
FI830879L (fi) 1983-09-20
ZA831882B (en) 1984-11-28
CA1190547A (en) 1985-07-16
US4474794A (en) 1984-10-02
RO85385B (ro) 1984-11-30
ATE27156T1 (de) 1987-05-15
GB2116973A (en) 1983-10-05
DK91083D0 (da) 1983-02-25
GB8307201D0 (en) 1983-04-20
EP0091220B1 (en) 1987-05-13
NZ203605A (en) 1985-10-11
PT76397A (en) 1983-04-01
ES8405386A1 (es) 1984-06-01
AU1254583A (en) 1983-09-22
IL68152A0 (en) 1983-06-15
DE3371514D1 (en) 1987-06-19
PT76397B (en) 1986-02-04
PH18504A (en) 1985-08-02
CS236788B2 (en) 1985-05-15
GR77882B (ro) 1984-09-25
ES520791A0 (es) 1984-06-01
EP0091220A2 (en) 1983-10-12
DD207376A5 (de) 1984-02-29
EP0091220A3 (en) 1984-05-23
FI830879A0 (fi) 1983-03-16
JPS58170773A (ja) 1983-10-07
KR840004091A (ko) 1984-10-06

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