AR230280A1 - Procedimiento para obtener derivados de carboestirilo y sus sales - Google Patents

Procedimiento para obtener derivados de carboestirilo y sus sales

Info

Publication number
AR230280A1
AR230280A1 AR282565A AR28256580A AR230280A1 AR 230280 A1 AR230280 A1 AR 230280A1 AR 282565 A AR282565 A AR 282565A AR 28256580 A AR28256580 A AR 28256580A AR 230280 A1 AR230280 A1 AR 230280A1
Authority
AR
Argentina
Prior art keywords
carboestirile
derivatives
salts
procedure
obtaining
Prior art date
Application number
AR282565A
Other languages
English (en)
Spanish (es)
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP12045279A external-priority patent/JPS5643280A/ja
Priority claimed from JP12556579A external-priority patent/JPS5649360A/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of AR230280A1 publication Critical patent/AR230280A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/52Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AR282565A 1979-09-18 1980-09-17 Procedimiento para obtener derivados de carboestirilo y sus sales AR230280A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP12045279A JPS5643280A (en) 1979-09-18 1979-09-18 Carbostyril derivative
JP12556579A JPS5649360A (en) 1979-09-28 1979-09-28 2-oxoquinoline derivative

Publications (1)

Publication Number Publication Date
AR230280A1 true AR230280A1 (es) 1984-03-01

Family

ID=26458032

Family Applications (2)

Application Number Title Priority Date Filing Date
AR282565A AR230280A1 (es) 1979-09-18 1980-09-17 Procedimiento para obtener derivados de carboestirilo y sus sales
AR289431A AR230059A1 (es) 1979-09-18 1982-05-18 Procedimiento para obtener derivados de piperidil-1-il-alcoxi o hidroxialcoxi-carboestirilo o 3,4-dihidrocarboestirilo

Family Applications After (1)

Application Number Title Priority Date Filing Date
AR289431A AR230059A1 (es) 1979-09-18 1982-05-18 Procedimiento para obtener derivados de piperidil-1-il-alcoxi o hidroxialcoxi-carboestirilo o 3,4-dihidrocarboestirilo

Country Status (19)

Country Link
US (1) US4482560A (fr)
AR (2) AR230280A1 (fr)
AT (1) AT376972B (fr)
AU (1) AU518144B2 (fr)
CA (1) CA1151172A (fr)
CH (1) CH645892A5 (fr)
DE (1) DE3034237A1 (fr)
DK (1) DK158984C (fr)
ES (1) ES8200679A1 (fr)
FI (1) FI76322C (fr)
FR (1) FR2465732A1 (fr)
GB (1) GB2063869B (fr)
IT (1) IT1129263B (fr)
MX (1) MX6806E (fr)
NL (1) NL187912C (fr)
NO (1) NO154841C (fr)
PT (1) PT71810B (fr)
SE (1) SE439632B (fr)
SU (1) SU1091857A3 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2901336A1 (de) 1979-01-15 1980-07-24 Boehringer Mannheim Gmbh Neue arylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
CH655110A5 (de) * 1982-09-03 1986-03-27 Otsuka Pharma Co Ltd Carbostyrilderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten.
GB8426584D0 (en) * 1984-10-19 1984-11-28 Beecham Group Plc Compounds
US4704390A (en) * 1986-02-13 1987-11-03 Warner-Lambert Company Phenyl and heterocyclic tetrahydropyridyl alkoxy-benzheterocyclic compounds as antipsychotic agents
US4792561A (en) * 1986-05-29 1988-12-20 Syntex (U.S.A.) Inc. Carbostyril derivatives as combined thromboxane synthetase and cyclic-AMP phosphodiesterase inhibitors
US4921862A (en) * 1986-05-29 1990-05-01 Syntex (U.S.A.) Inc. Carbostyril derivatives as combined thromboxane synthetase and cyclic-amp phosphodiesterase inhibitors
DK397387A (da) * 1986-07-31 1988-02-01 Otsuka Pharma Co Ltd Carbostyrilderivater og salte deraf samt fremgangsmaade til fremstilling af saadanne forbindelser
FR2620704B1 (fr) * 1987-09-17 1991-04-26 Sanofi Sa Derives de (benzyl-4 piperidino)-1 propanol-2, leur preparation, leur utilisation comme antimicrobiens et les produits les contenant
US5227381A (en) * 1988-05-02 1993-07-13 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivative
US5082847A (en) * 1990-07-18 1992-01-21 Syntex (U.S.A.) Inc. Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility
JP2686887B2 (ja) * 1992-08-11 1997-12-08 キッセイ薬品工業株式会社 ピペリジノ−3,4−ジヒドロカルボスチリル誘導体
IT1264816B1 (it) * 1993-07-28 1996-10-10 Pergam Srl Procedimento per la preparazione di derivati del procedimento per la preparazione di derivati del 3,4-diidrocarbostirile 3,4-diidrocarbostirile
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610736B (en) 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
WO2001087834A1 (fr) * 2000-05-16 2001-11-22 Takeda Chemical Industries, Ltd. Antagoniste de l'hormone de concentration de la melanine
BR0305500A (pt) 2003-01-09 2004-11-03 Otsuka Pharma Co Ltd Processo para preparar aripiprazol
DE102008022221A1 (de) 2008-05-06 2009-11-12 Universität des Saarlandes Inhibitoren der humanen Aldosteronsynthase CYP11B2
US8541404B2 (en) 2009-11-09 2013-09-24 Elexopharm Gmbh Inhibitors of the human aldosterone synthase CYP11B2

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3629266A (en) * 1969-03-03 1971-12-21 Miles Lab (phenyl piperidino alkyl)3 4-dihydrocarbostyrils
JPS517672B2 (fr) * 1972-04-13 1976-03-10
US3910924A (en) * 1972-04-13 1975-10-07 Otsuka Pharma Co Ltd 3,4-Dihydrocarbostyril derivatives and a process for preparing the same
US4256890A (en) * 1972-09-14 1981-03-17 Otsukapharmaceutical Co., Ltd. 3,4-Dihydrocarbostyril derivatives and process for producing the same
JPS5239035B2 (fr) * 1972-12-14 1977-10-03
JPS5310986B2 (fr) * 1974-02-05 1978-04-18
JPS5310989B2 (fr) * 1974-04-25 1978-04-18
US3994900A (en) * 1976-01-23 1976-11-30 E. R. Squibb & Sons, Inc. 6-(Or 8)-[[(substituted amino)alkyl]oxy(or thio)]-3,4-dihydro-4-phenyl-2(1H)-quinolinones
US4210753A (en) * 1976-03-17 1980-07-01 Otsuka Pharmaceutical Co., Ltd. Carbostyril compounds
CH619453A5 (fr) * 1976-03-17 1980-09-30 Otsuka Pharma Co Ltd
JPS609501B2 (ja) * 1976-05-07 1985-03-11 大塚製薬株式会社 新規3,4−ジヒドロカルボスチリル誘導体
JPS5919541B2 (ja) * 1976-03-17 1984-05-07 大塚製薬株式会社 新規3,4−ジヒドロカルボスチリル誘導体
DE2719562C2 (de) * 1976-05-08 1986-05-07 Otsuka Pharmaceutical Co. Ltd., Tokio/Tokyo 3, 4-Dihydrocarbostyrilderivate, Verfahren zu deren Herstellung und Arzneimittel, welche diese enthalten
JPS6019295B2 (ja) * 1977-03-04 1985-05-15 大塚製薬株式会社 カルボスチリル誘導体及びその製造法
JPS5416478A (en) * 1977-07-08 1979-02-07 Otsuka Pharmaceut Co Ltd 3,4-dihydrocarbostyril herivative
JPS54130587A (en) * 1978-03-30 1979-10-09 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
DE2827566A1 (de) * 1978-06-23 1980-01-10 Boehringer Mannheim Gmbh 1,2-dihydro-chinolin-2-on-derivate und verfahren zu ihrer herstellung
JPS5589221A (en) * 1978-12-28 1980-07-05 Otsuka Pharmaceut Co Ltd Antihistaminic agent
JPS5589222A (en) * 1978-12-28 1980-07-05 Otsuka Pharmaceut Co Ltd Antihistaminic agent
DE2901336A1 (de) * 1979-01-15 1980-07-24 Boehringer Mannheim Gmbh Neue arylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
NO154841C (no) 1987-01-07
AT376972B (de) 1985-01-25
DE3034237A1 (de) 1981-04-16
IT1129263B (it) 1986-06-04
FI76322C (fi) 1988-10-10
FI76322B (fi) 1988-06-30
PT71810B (en) 1981-07-07
FI802905A (fi) 1981-03-19
NL8005188A (nl) 1981-03-20
FR2465732A1 (fr) 1981-03-27
NL187912B (nl) 1991-09-16
SU1091857A3 (ru) 1984-05-07
NO802762L (no) 1981-03-19
DK158984B (da) 1990-08-13
GB2063869B (en) 1983-05-25
CH645892A5 (de) 1984-10-31
AU6238180A (en) 1981-05-28
CA1151172A (fr) 1983-08-02
ATA465780A (de) 1984-06-15
US4482560A (en) 1984-11-13
GB2063869A (en) 1981-06-10
NO154841B (no) 1986-09-22
ES495163A0 (es) 1981-11-16
SE8006498L (sv) 1981-03-19
DK394080A (da) 1981-03-19
AU518144B2 (en) 1981-09-17
DK158984C (da) 1991-01-14
ES8200679A1 (es) 1981-11-16
FR2465732B1 (fr) 1983-06-24
MX6806E (es) 1986-07-30
PT71810A (en) 1980-10-01
IT8068445A0 (it) 1980-09-18
SE439632B (sv) 1985-06-24
NL187912C (nl) 1992-02-17
DE3034237C2 (fr) 1988-04-21
AR230059A1 (es) 1984-02-29

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