AR114921A2 - Método para preparar 2-amino-n-(2,2,2-trifluoroetil)acetamida - Google Patents

Método para preparar 2-amino-n-(2,2,2-trifluoroetil)acetamida

Info

Publication number
AR114921A2
AR114921A2 ARP190101556A ARP190101556A AR114921A2 AR 114921 A2 AR114921 A2 AR 114921A2 AR P190101556 A ARP190101556 A AR P190101556A AR P190101556 A ARP190101556 A AR P190101556A AR 114921 A2 AR114921 A2 AR 114921A2
Authority
AR
Argentina
Prior art keywords
preparing
formula
trifluoroethyl
acetamide
amino
Prior art date
Application number
ARP190101556A
Other languages
English (en)
Inventor
Joerg Bruening
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of AR114921A2 publication Critical patent/AR114921A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Reivindicación 1: Un método para preparar un compuesto de la fórmula (1), en donde X es Cl, Br, CF₃CO₂, CH₃SO₃, (SO₄)₁/₂ o (PO₄)₁/₃, caracterizado porque el método comprende (A1) contactar un compuesto de la fórmula (2) con un compuesto de la fórmula (3) y un reactivo de acoplamiento para formar un intermedio de la fórmula (4) en presencia de una base, y (B1) contactar el intermedio de la fórmula (4) con un ácido de la fórmula HX.
ARP190101556A 2010-09-27 2019-06-06 Método para preparar 2-amino-n-(2,2,2-trifluoroetil)acetamida AR114921A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38667310P 2010-09-27 2010-09-27

Publications (1)

Publication Number Publication Date
AR114921A2 true AR114921A2 (es) 2020-10-28

Family

ID=44741725

Family Applications (3)

Application Number Title Priority Date Filing Date
ARP110103504A AR083105A1 (es) 2010-09-27 2011-09-26 Metodo para preparar 2-amino-n-(2,2,2-trifluoroetil)acetamida
ARP190101556A AR114921A2 (es) 2010-09-27 2019-06-06 Método para preparar 2-amino-n-(2,2,2-trifluoroetil)acetamida
ARP190101555A AR114920A2 (es) 2010-09-27 2019-06-06 Método para preparar 2-amino-n-(2,2,2-trifluoroetil)acetamida

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP110103504A AR083105A1 (es) 2010-09-27 2011-09-26 Metodo para preparar 2-amino-n-(2,2,2-trifluoroetil)acetamida

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP190101555A AR114920A2 (es) 2010-09-27 2019-06-06 Método para preparar 2-amino-n-(2,2,2-trifluoroetil)acetamida

Country Status (20)

Country Link
US (4) US10202332B2 (es)
EP (2) EP2621894B1 (es)
JP (2) JP5859010B2 (es)
KR (1) KR101901466B1 (es)
CN (1) CN103124721B (es)
AR (3) AR083105A1 (es)
AU (3) AU2011312599B2 (es)
BR (3) BR122018074319B8 (es)
CA (4) CA3021290C (es)
ES (2) ES2962793T3 (es)
IL (3) IL225147A (es)
LT (2) LT3150575T (es)
MX (2) MX341417B (es)
MY (1) MY161570A (es)
PT (2) PT2621894T (es)
RU (1) RU2581841C2 (es)
TW (3) TWI535685B (es)
UA (1) UA113615C2 (es)
WO (1) WO2012047543A1 (es)
ZA (1) ZA201301830B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014028758A (ja) 2010-11-19 2014-02-13 Nissan Chem Ind Ltd 寄生虫及び衛生害虫防除剤
WO2020222158A1 (en) * 2019-04-30 2020-11-05 Hikal Limited Process for the preparation of 2-amino-n-(2,2,2-trifluoroethyl)-acetamide and salts thereof
CN114057594A (zh) * 2020-07-31 2022-02-18 广东东阳光药业有限公司 2-氨基-n-(2,2,2-三氟乙基)乙酰胺或其盐的制备方法
CN115710185B (zh) * 2021-08-23 2024-05-03 中国石油化工股份有限公司 利用金属碳化物催化剂生产甲胺的方法
CN114414678B (zh) * 2021-12-27 2023-05-30 丽珠集团新北江制药股份有限公司 一种异噁唑啉类兽药中间体铵盐有关杂质的分析方法
WO2023145372A1 (ja) * 2022-01-28 2023-08-03 日本曹達株式会社 アミド化合物の製造方法
CN115536541A (zh) * 2022-10-13 2022-12-30 湖北美天生物科技股份有限公司 氟雷拉纳和阿福拉纳共同中间体的合成方法
CN116903488B (zh) * 2022-11-25 2023-12-15 济南久隆医药科技有限公司 一种阿福拉纳的合成方法
CN115772091B (zh) * 2023-01-05 2023-06-23 济南久隆医药科技有限公司 一种2-氨基-n-(2,2,2-三氟乙基)乙酰胺的合成方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4484001A (en) * 1983-11-18 1984-11-20 Ppg Industries, Inc. Method for preparing N-benzyloxycarbonyl amino acids containing additional functionality
ATE99698T1 (de) * 1985-10-14 1994-01-15 Nippon Zoki Pharmaceutical Co Peptide.
US5952497A (en) * 1996-07-10 1999-09-14 University Of Georgia Research Foundation N.sup.α -Bpoc amino acid pentafluorophenyl (Pfp) esters and 3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl (ODhbt) esters
JP2979139B2 (ja) * 1998-03-11 1999-11-15 東北大学長 Ｌ−パラボロノフェニルアラニンの製造方法
US6472415B1 (en) * 1998-12-18 2002-10-29 Biophysica, Inc. Androgen receptor suppressors in the therapy and diagnosis of prostate cancer, alopecia and other hyper-androgenic syndromes
US7297712B2 (en) * 2002-03-27 2007-11-20 Council Of Scientific And Industrial Research Cationic amphiphiles for intracellular delivery of therapeutic molecules and its composition, process and method of treatment
US20040077618A1 (en) * 2002-10-22 2004-04-22 Bennani Youssef L. Cycloalkylamides and their therapeutic applications
US8017151B2 (en) * 2004-09-07 2011-09-13 Board Of Regents Of The University Of Nebraska By And Behalf Of The University Of Nebraska Medical Center Amphiphilic polymer-protein conjugates and methods of use thereof
TW200643015A (en) * 2005-03-11 2006-12-16 Akzo Nobel Nv 2-(4-oxo-4H-quinazolin-3-yl)acetamide derivatives
US20080194623A1 (en) * 2005-08-02 2008-08-14 Labaw Clifford S Method for the Synthesis of Quinoline Derivatives
EP1801086A1 (en) * 2005-11-25 2007-06-27 Synthacon GmbH Synthesis of carbon acid amides
KR20090122931A (ko) * 2007-03-26 2009-12-01 아스테라스 세이야쿠 가부시키가이샤 오르니틴 유도체
TWI649303B (zh) 2007-08-17 2019-02-01 杜邦股份有限公司 製備４-乙醯基-ｎ-〔２-側氧基-２-〔（２，２，２-三氟乙基）胺基〕乙基〕-１-萘甲醯胺之化合物及方法
GB2453770A (en) * 2007-10-19 2009-04-22 Reckitt Benckiser Healthcare Oral composition comprising a cooling agent
JP5403205B2 (ja) * 2007-10-29 2014-01-29 日産化学工業株式会社 ２−アミノ−ｎ−（２，２，２−トリフルオロエチル）アセトアミド化合物又はその塩の製造方法
TWI455919B (zh) 2008-04-09 2014-10-11 Du Pont 製備３－三氟甲基查耳酮（ｃｈａｌｃｏｎｅ）之方法
ES2582575T3 (es) * 2008-07-09 2016-09-13 Nissan Chemical Industries, Ltd. Procedimiento para la producción de compuesto de amida del ácido benzoico sustituido con isoxazolina
EP2379537B9 (en) * 2008-12-19 2017-07-12 Novartis AG Isoxazoline derivatives and their use as pesticide
BRPI0918305A2 (pt) * 2008-12-23 2015-08-11 Basf Se Compostos de amidina substituídos da fórmula (i), composto de amidina substituído da fórmula (i-5), composto de amidina substituído de 4-hidróximinometil da fórmula geral (ii-a), composto de amidina substituído de 4-hidróximinometil da fórmula geral (ii-b), composição agrícola, composição veterinária, uso de um composto, método para controlar pragas de invertebrados, método para proteger culturas ou plantas de ataque ou infestação por pragas de invertebrados, método para proteger material de propagação da planta e/ou as plantas, material de propagação da planta, método para tratar ou proteger um animal de infestação ou infecção por pragas de invertebrados e uso de um composto da fórmula i
MX2012003023A (es) * 2009-09-24 2012-04-10 Sanofi Aventis Us Llc Sintesis del ester terc-butilico del acido (4-fluoro-3-piperidin-4 -il-bencil)-carbamico y sus productos intermedios.

Also Published As

Publication number Publication date
TWI535685B (zh) 2016-06-01
RU2581841C2 (ru) 2016-04-20
ES2962793T3 (es) 2024-03-21
BR112013007040B8 (pt) 2022-11-08
IL225147A (en) 2017-04-30
EP2621894B1 (en) 2016-11-16
BR122018074319B1 (pt) 2020-02-27
IL270711B (en) 2021-09-30
CA3021290A1 (en) 2012-04-12
IL270711A (en) 2020-01-30
AR114920A2 (es) 2020-10-28
BR112013007040B1 (pt) 2019-04-02
EP2621894A1 (en) 2013-08-07
CN103124721B (zh) 2015-06-03
CA3197676A1 (en) 2012-04-12
TWI591046B (zh) 2017-07-11
AU2018201421A1 (en) 2018-03-22
CN103124721A (zh) 2013-05-29
PT2621894T (pt) 2017-01-04
MX341417B (es) 2016-08-19
PT3150575T (pt) 2023-11-13
US20190144373A1 (en) 2019-05-16
US11613516B2 (en) 2023-03-28
AU2018201421B2 (en) 2019-05-02
RU2013119617A (ru) 2014-11-10
AU2011312599A1 (en) 2013-03-28
WO2012047543A1 (en) 2012-04-12
LT3150575T (lt) 2023-12-27
US10202332B2 (en) 2019-02-12
CA2812718A1 (en) 2012-04-12
UA113615C2 (xx) 2017-02-27
US20230303482A1 (en) 2023-09-28
IL250489B (en) 2019-12-31
ZA201301830B (en) 2014-04-28
JP2013537914A (ja) 2013-10-07
TW201623220A (zh) 2016-07-01
TW201720792A (zh) 2017-06-16
AR083105A1 (es) 2013-01-30
BR122018074319B8 (pt) 2022-12-06
AU2016202641B2 (en) 2017-11-30
MX2013003462A (es) 2013-05-28
CA2812718C (en) 2018-11-27
AU2016202641A1 (en) 2016-05-19
US20190144374A1 (en) 2019-05-16
CA3021290C (en) 2021-05-25
AU2011312599B2 (en) 2016-02-25
CA3111132A1 (en) 2012-04-12
MY161570A (en) 2017-04-28
JP6175122B2 (ja) 2017-08-02
US20130267729A1 (en) 2013-10-10
IL250489A0 (en) 2017-03-30
LT2621894T (lt) 2017-01-25
TW201213281A (en) 2012-04-01
EP3150575A1 (en) 2017-04-05
KR20130099121A (ko) 2013-09-05
JP2016117720A (ja) 2016-06-30
KR101901466B1 (ko) 2018-09-21
BR112013007040A2 (pt) 2016-06-14
JP5859010B2 (ja) 2016-02-10
ES2614812T3 (es) 2017-06-02
MX346782B (es) 2017-03-31
BR122018074306B8 (pt) 2022-12-06
US10745344B2 (en) 2020-08-18
EP3150575B1 (en) 2023-08-09
BR122018074306B1 (pt) 2020-02-27
CA3111132C (en) 2023-06-20

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