BR122018074319B8 - Método para preparar um composto de fórmula 14 - Google Patents

Método para preparar um composto de fórmula 14

Info

Publication number
BR122018074319B8
BR122018074319B8 BR122018074319A BR122018074319A BR122018074319B8 BR 122018074319 B8 BR122018074319 B8 BR 122018074319B8 BR 122018074319 A BR122018074319 A BR 122018074319A BR 122018074319 A BR122018074319 A BR 122018074319A BR 122018074319 B8 BR122018074319 B8 BR 122018074319B8
Authority
BR
Brazil
Prior art keywords
compound
formula
preparing
relates
present
Prior art date
Application number
BR122018074319A
Other languages
English (en)
Other versions
BR122018074319B1 (pt
Inventor
Bruening Joerg
Original Assignee
Du Pont
Corteva Agriscience Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont, Corteva Agriscience Llc filed Critical Du Pont
Publication of BR122018074319B1 publication Critical patent/BR122018074319B1/pt
Publication of BR122018074319B8 publication Critical patent/BR122018074319B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

A presente invenção refere-se a um método para preparação de um composto de fórmula 14 a partir de um composto de fórmula 15 e um composto de fórmula 1 ou 1A.
BR122018074319A 2010-09-27 2011-09-23 Método para preparar um composto de fórmula 14 BR122018074319B8 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US38667310P 2010-09-27 2010-09-27
US61/386,673 2010-09-27
PCT/US2011/052938 WO2012047543A1 (en) 2010-09-27 2011-09-23 Method for preparing 2-amino-n-(2,2,2-trifluoroethyl) acetamide
BR112013007040A BR112013007040B8 (pt) 2010-09-27 2011-09-23 Método para preparar um composto de fórmula 1

Publications (2)

Publication Number Publication Date
BR122018074319B1 BR122018074319B1 (pt) 2020-02-27
BR122018074319B8 true BR122018074319B8 (pt) 2022-12-06

Family

ID=44741725

Family Applications (3)

Application Number Title Priority Date Filing Date
BR122018074319A BR122018074319B8 (pt) 2010-09-27 2011-09-23 Método para preparar um composto de fórmula 14
BR122018074306A BR122018074306B8 (pt) 2010-09-27 2011-09-23 Método para preparar um composto de fórmula 1a
BR112013007040A BR112013007040B8 (pt) 2010-09-27 2011-09-23 Método para preparar um composto de fórmula 1

Family Applications After (2)

Application Number Title Priority Date Filing Date
BR122018074306A BR122018074306B8 (pt) 2010-09-27 2011-09-23 Método para preparar um composto de fórmula 1a
BR112013007040A BR112013007040B8 (pt) 2010-09-27 2011-09-23 Método para preparar um composto de fórmula 1

Country Status (20)

Country Link
US (4) US10202332B2 (pt)
EP (2) EP3150575B1 (pt)
JP (2) JP5859010B2 (pt)
KR (1) KR101901466B1 (pt)
CN (1) CN103124721B (pt)
AR (3) AR083105A1 (pt)
AU (3) AU2011312599B2 (pt)
BR (3) BR122018074319B8 (pt)
CA (4) CA3021290C (pt)
ES (2) ES2962793T3 (pt)
IL (3) IL225147A (pt)
LT (2) LT3150575T (pt)
MX (2) MX346782B (pt)
MY (1) MY161570A (pt)
PT (2) PT2621894T (pt)
RU (1) RU2581841C2 (pt)
TW (3) TWI535685B (pt)
UA (1) UA113615C2 (pt)
WO (1) WO2012047543A1 (pt)
ZA (1) ZA201301830B (pt)

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JP2014028758A (ja) 2010-11-19 2014-02-13 Nissan Chem Ind Ltd 寄生虫及び衛生害虫防除剤
WO2020222158A1 (en) * 2019-04-30 2020-11-05 Hikal Limited Process for the preparation of 2-amino-n-(2,2,2-trifluoroethyl)-acetamide and salts thereof
CN114057594A (zh) * 2020-07-31 2022-02-18 广东东阳光药业有限公司 2-氨基-n-(2,2,2-三氟乙基)乙酰胺或其盐的制备方法
CN115710185B (zh) * 2021-08-23 2024-05-03 中国石油化工股份有限公司 利用金属碳化物催化剂生产甲胺的方法
CN114414678B (zh) * 2021-12-27 2023-05-30 丽珠集团新北江制药股份有限公司 一种异噁唑啉类兽药中间体铵盐有关杂质的分析方法
JPWO2023145372A1 (pt) * 2022-01-28 2023-08-03
CN115536541A (zh) * 2022-10-13 2022-12-30 湖北美天生物科技股份有限公司 氟雷拉纳和阿福拉纳共同中间体的合成方法
CN116253658B (zh) * 2022-11-25 2023-08-11 济南久隆医药科技有限公司 一种阿福拉纳中间体合成方法
CN115772091B (zh) * 2023-01-05 2023-06-23 济南久隆医药科技有限公司 一种2-氨基-n-(2,2,2-三氟乙基)乙酰胺的合成方法
CN116143652B (zh) * 2023-01-13 2024-06-28 四川青木制药有限公司 一种阿福拉纳中间体及其制备方法和应用

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US4484001A (en) * 1983-11-18 1984-11-20 Ppg Industries, Inc. Method for preparing N-benzyloxycarbonyl amino acids containing additional functionality
ATE99698T1 (de) * 1985-10-14 1994-01-15 Nippon Zoki Pharmaceutical Co Peptide.
US5952497A (en) * 1996-07-10 1999-09-14 University Of Georgia Research Foundation N.sup.α -Bpoc amino acid pentafluorophenyl (Pfp) esters and 3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl (ODhbt) esters
JP2979139B2 (ja) * 1998-03-11 1999-11-15 東北大学長 Ｌ−パラボロノフェニルアラニンの製造方法
US6472415B1 (en) * 1998-12-18 2002-10-29 Biophysica, Inc. Androgen receptor suppressors in the therapy and diagnosis of prostate cancer, alopecia and other hyper-androgenic syndromes
US7297712B2 (en) * 2002-03-27 2007-11-20 Council Of Scientific And Industrial Research Cationic amphiphiles for intracellular delivery of therapeutic molecules and its composition, process and method of treatment
US20040077618A1 (en) * 2002-10-22 2004-04-22 Bennani Youssef L. Cycloalkylamides and their therapeutic applications
US8017151B2 (en) * 2004-09-07 2011-09-13 Board Of Regents Of The University Of Nebraska By And Behalf Of The University Of Nebraska Medical Center Amphiphilic polymer-protein conjugates and methods of use thereof
TW200643015A (en) * 2005-03-11 2006-12-16 Akzo Nobel Nv 2-(4-oxo-4H-quinazolin-3-yl)acetamide derivatives
EP1919871A4 (en) * 2005-08-02 2010-08-18 Glaxosmithkline Llc PROCESS FOR SYNTHESIS OF CHINOLINE DERIVATIVES
EP1801086A1 (en) * 2005-11-25 2007-06-27 Synthacon GmbH Synthesis of carbon acid amides
WO2008123207A1 (ja) * 2007-03-26 2008-10-16 Astellas Pharma Inc. オルニチン誘導体
TWI649303B (zh) 2007-08-17 2019-02-01 杜邦股份有限公司 製備４-乙醯基-ｎ-〔２-側氧基-２-〔（２，２，２-三氟乙基）胺基〕乙基〕-１-萘甲醯胺之化合物及方法
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Also Published As

Publication number Publication date
BR112013007040B1 (pt) 2019-04-02
WO2012047543A1 (en) 2012-04-12
MX346782B (es) 2017-03-31
JP6175122B2 (ja) 2017-08-02
UA113615C2 (xx) 2017-02-27
TW201720792A (zh) 2017-06-16
CA3021290C (en) 2021-05-25
IL270711A (en) 2020-01-30
PT2621894T (pt) 2017-01-04
ES2614812T3 (es) 2017-06-02
EP3150575A1 (en) 2017-04-05
ES2962793T3 (es) 2024-03-21
EP3150575B1 (en) 2023-08-09
KR20130099121A (ko) 2013-09-05
IL225147A (en) 2017-04-30
TWI535685B (zh) 2016-06-01
AR114921A2 (es) 2020-10-28
AR114920A2 (es) 2020-10-28
MY161570A (en) 2017-04-28
LT2621894T (lt) 2017-01-25
BR122018074306B1 (pt) 2020-02-27
AU2018201421A1 (en) 2018-03-22
AU2011312599A1 (en) 2013-03-28
PT3150575T (pt) 2023-11-13
BR122018074319B1 (pt) 2020-02-27
US20190144374A1 (en) 2019-05-16
US20230303482A1 (en) 2023-09-28
US10202332B2 (en) 2019-02-12
BR112013007040A2 (pt) 2016-06-14
CA2812718C (en) 2018-11-27
CA3021290A1 (en) 2012-04-12
CA3197676A1 (en) 2012-04-12
AU2016202641A1 (en) 2016-05-19
AU2018201421B2 (en) 2019-05-02
TW201213281A (en) 2012-04-01
LT3150575T (lt) 2023-12-27
JP2016117720A (ja) 2016-06-30
JP5859010B2 (ja) 2016-02-10
CN103124721B (zh) 2015-06-03
RU2013119617A (ru) 2014-11-10
TW201623220A (zh) 2016-07-01
RU2581841C2 (ru) 2016-04-20
EP2621894A1 (en) 2013-08-07
IL250489B (en) 2019-12-31
AR083105A1 (es) 2013-01-30
CN103124721A (zh) 2013-05-29
TWI591046B (zh) 2017-07-11
IL250489A0 (en) 2017-03-30
CA2812718A1 (en) 2012-04-12
EP2621894B1 (en) 2016-11-16
KR101901466B1 (ko) 2018-09-21
US20130267729A1 (en) 2013-10-10
JP2013537914A (ja) 2013-10-07
IL270711B (en) 2021-09-30
BR112013007040B8 (pt) 2022-11-08
AU2011312599B2 (en) 2016-02-25
US10745344B2 (en) 2020-08-18
CA3111132A1 (en) 2012-04-12
US11613516B2 (en) 2023-03-28
AU2016202641B2 (en) 2017-11-30
MX341417B (es) 2016-08-19
CA3111132C (en) 2023-06-20
US20190144373A1 (en) 2019-05-16
ZA201301830B (en) 2014-04-28
MX2013003462A (es) 2013-05-28
BR122018074306B8 (pt) 2022-12-06

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 23/09/2011, OBSERVADAS AS CONDICOES LEGAIS.

B25A Requested transfer of rights approved

Owner name: CORTEVA AGRISCIENCE LLC (US)