AR096243A1 - Inhibidores de acc y usos de los mismos - Google Patents
Inhibidores de acc y usos de los mismosInfo
- Publication number
- AR096243A1 AR096243A1 ARP140101890A ARP140101890A AR096243A1 AR 096243 A1 AR096243 A1 AR 096243A1 AR P140101890 A ARP140101890 A AR P140101890A AR P140101890 A ARP140101890 A AR P140101890A AR 096243 A1 AR096243 A1 AR 096243A1
- Authority
- AR
- Argentina
- Prior art keywords
- membered
- ring
- independently selected
- sulfur
- nitrogen
- Prior art date
Links
- 229940121373 acetyl-coa carboxylase inhibitor Drugs 0.000 title 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 13
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 11
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 11
- 125000005842 heteroatom Chemical group 0.000 abstract 11
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 11
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 11
- 229910052760 oxygen Inorganic materials 0.000 abstract 11
- 239000001301 oxygen Chemical group 0.000 abstract 11
- 229910052717 sulfur Chemical group 0.000 abstract 11
- 239000011593 sulfur Chemical group 0.000 abstract 11
- 229920006395 saturated elastomer Polymers 0.000 abstract 7
- 125000000623 heterocyclic group Chemical group 0.000 abstract 5
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 125000002950 monocyclic group Chemical group 0.000 abstract 4
- 125000005843 halogen group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- YZCKVEUIGOORGS-OUBTZVSYSA-N Deuterium Chemical group [2H] YZCKVEUIGOORGS-OUBTZVSYSA-N 0.000 abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 229910052805 deuterium Inorganic materials 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000005605 benzo group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000003566 oxetanyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Zoology (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epidemiology (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361821829P | 2013-05-10 | 2013-05-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR096243A1 true AR096243A1 (es) | 2015-12-16 |
Family
ID=51867754
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP140101890A AR096243A1 (es) | 2013-05-10 | 2014-05-09 | Inhibidores de acc y usos de los mismos |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9765089B2 (enExample) |
| EP (1) | EP2994128B1 (enExample) |
| JP (1) | JP6417402B2 (enExample) |
| KR (1) | KR20160005364A (enExample) |
| CN (1) | CN105358143B (enExample) |
| AR (1) | AR096243A1 (enExample) |
| AU (1) | AU2014262546B2 (enExample) |
| BR (1) | BR112015028173A2 (enExample) |
| CA (1) | CA2911818A1 (enExample) |
| CL (1) | CL2015003316A1 (enExample) |
| EA (1) | EA030958B1 (enExample) |
| HK (2) | HK1221660A1 (enExample) |
| MX (1) | MX2015015421A (enExample) |
| WO (1) | WO2014182950A1 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105358152A (zh) * | 2013-05-10 | 2016-02-24 | 尼普斯阿波罗有限公司 | Acc抑制剂和其用途 |
| EP2994141A4 (en) | 2013-05-10 | 2016-11-23 | Nimbus Apollo Inc | ACC-HEMMER AND USES THEREOF |
| HK1221661A1 (zh) | 2013-05-10 | 2017-06-09 | Gilead Apollo, Llc | Acc抑制剂和其用途 |
| US10150728B2 (en) | 2013-10-17 | 2018-12-11 | Shionogi & Co., Ltd. | Alkylene derivatives |
| US10202361B2 (en) | 2014-08-29 | 2019-02-12 | Fmc Corporation | Pyridazinones as herbicides |
| CN107106873A (zh) | 2015-01-09 | 2017-08-29 | 吉利德阿波罗公司 | 用于治疗非酒精性脂肪肝病的acc抑制剂组合治疗 |
| UY36586A (es) | 2015-03-26 | 2016-10-31 | Bayer Pharma AG | Heterociclilmetiltienouracilos y uso de los mismos |
| GB201512286D0 (en) * | 2015-07-14 | 2015-08-19 | F2G Ltd | Chemical compounds |
| AR106472A1 (es) * | 2015-10-26 | 2018-01-17 | Gilead Apollo Llc | Inhibidores de acc y usos de los mismos |
| US20170166583A1 (en) | 2015-11-25 | 2017-06-15 | Gilead Apollo, Llc | Ester acc inhibitors and uses thereof |
| EP3380480B1 (en) * | 2015-11-25 | 2022-12-14 | Gilead Apollo, LLC | Pyrazole acc inhibitors and uses thereof |
| BR112018009212B1 (pt) | 2015-11-25 | 2022-06-14 | Gilead Apollo, Llc | Método para controlar patógenos fúngicos agrícolas |
| WO2017091617A1 (en) * | 2015-11-25 | 2017-06-01 | Gilead Apollo, Llc | Triazole acc inhibitors and uses thereof |
| WO2017100703A1 (en) * | 2015-12-10 | 2017-06-15 | Colin Combs | Ems analogues of lyn/src-tyrosine kinase inhibitors |
| US10183951B2 (en) | 2016-03-02 | 2019-01-22 | Gilead Apollo, Llc | Solid forms of a thienopyrimidinedione ACC inhibitor and methods for production thereof |
| WO2018041771A1 (de) | 2016-09-02 | 2018-03-08 | Bayer Pharma Aktiengesellschaft | (1-methylcyclopropyl)methyl-substituierte thienouracile und ihre verwendung |
| KR20190053242A (ko) | 2016-09-23 | 2019-05-17 | 바이엘 악티엔게젤샤프트 | N3-시클릭 치환된 티에노우라실 및 그의 용도 |
| WO2018133858A1 (en) | 2017-01-22 | 2018-07-26 | Sunshine Lake Pharma Co., Ltd. | Thienopyrimidine derivative and use thereof in medicine |
| CN110431143B (zh) * | 2017-03-24 | 2022-08-12 | 浙江海正药业股份有限公司 | 杂芳基并嘧啶酮类衍生物及其制备方法和用途 |
| CN110431144B (zh) * | 2017-03-24 | 2022-08-05 | 浙江海正药业股份有限公司 | 氰基取代的杂芳基并嘧啶酮类衍生物及其制备方法和用途 |
| JP6906626B2 (ja) | 2017-03-28 | 2021-07-21 | ギリアード サイエンシーズ， インコーポレイテッド | 肝疾患を処置するための治療的組み合わせ |
| CN111050750B (zh) | 2017-08-24 | 2024-09-24 | 诺和诺德股份有限公司 | Glp-1组合物及其用途 |
| KR20190036705A (ko) | 2017-09-28 | 2019-04-05 | 한미약품 주식회사 | (2r)-2-(2-메톡시페닐)-2-(옥산-4-일옥시)에탄-1-올 화합물의 신규 제조방법 및 이에 사용되는 중간체 |
| WO2019233443A1 (zh) | 2018-06-05 | 2019-12-12 | 南京明德新药研发有限公司 | 噻吩并[2,3-c]哒嗪-4(1H)-酮类衍生物及其应用 |
| US12428432B2 (en) | 2019-07-02 | 2025-09-30 | Sunshine Lake Pharma Co., Ltd. | Thienopyrimidine derivatives having stereo configurations and use thereof in medicine |
| AR119594A1 (es) | 2019-08-09 | 2021-12-29 | Gilead Sciences Inc | Derivados de tienopirimidina como inhibidores acc y usos de los mismos |
| US11673899B2 (en) * | 2019-12-05 | 2023-06-13 | Zhangzhou Pien Tze Huang Pharmaceutical Co., Ltd. | Crystal form of thieno[2,3-c]pyridazine-4(1H)-one compound, preparation method therefor and use thereof |
| WO2021112213A1 (ja) * | 2019-12-05 | 2021-06-10 | 日本曹達株式会社 | ２，４－ジオキソ－１，４－ジヒドロチエノピリミジン化合物、及びそれを含有する農園芸用殺菌剤又は医療用・動物用抗真菌剤 |
| JP7761567B2 (ja) | 2020-02-18 | 2025-10-28 | ノヴォ ノルディスク アー／エス | 医薬製剤 |
| US11478533B2 (en) | 2020-04-27 | 2022-10-25 | Novo Nordisk A/S | Semaglutide for use in medicine |
| US20250082765A1 (en) * | 2021-07-26 | 2025-03-13 | Rao Dr Boggarapu Prakash | Molecules as anticancer agents for targeted treatment of breast and prostate cancer |
| WO2024089216A1 (en) | 2022-10-27 | 2024-05-02 | Syngenta Crop Protection Ag | Novel sulfur-containing heteroaryl carboxamide compounds |
| US12303604B1 (en) | 2024-10-16 | 2025-05-20 | Currax Pharmaceuticals Llc | Pharmaceutical formulations comprising naltrexone and/or bupropion |
Family Cites Families (114)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3060084A (en) | 1961-06-09 | 1962-10-23 | Du Pont | Improved homogeneous, readily dispersed, pesticidal concentrate |
| US3299566A (en) | 1964-06-01 | 1967-01-24 | Olin Mathieson | Water soluble film containing agricultural chemicals |
| US3325503A (en) | 1965-02-18 | 1967-06-13 | Diamond Alkali Co | Polychloro derivatives of mono- and dicyano pyridines and a method for their preparation |
| US3296272A (en) | 1965-04-01 | 1967-01-03 | Dow Chemical Co | Sulfinyl- and sulfonylpyridines |
| FR1453897A (fr) * | 1965-06-16 | 1966-07-22 | Dérivés du thiophène et de thiéno pyridazines | |
| US4144050A (en) | 1969-02-05 | 1979-03-13 | Hoechst Aktiengesellschaft | Micro granules for pesticides and process for their manufacture |
| US3920442A (en) | 1972-09-18 | 1975-11-18 | Du Pont | Water-dispersible pesticide aggregates |
| US4172714A (en) | 1976-12-20 | 1979-10-30 | E. I. Du Pont De Nemours And Company | Dry compactible, swellable herbicidal compositions and pellets produced therefrom |
| GB2095558B (en) | 1981-03-30 | 1984-10-24 | Avon Packers Ltd | Formulation of agricultural chemicals |
| DE3338292A1 (de) | 1983-10-21 | 1985-05-02 | Basf Ag, 6700 Ludwigshafen | 7-amino-azolo(1,5-a)-pyrimidine und diese enthaltende fungizide |
| CA1249832A (en) | 1984-02-03 | 1989-02-07 | Shionogi & Co., Ltd. | Azolyl cycloalkanol derivatives and agricultural fungicides |
| US5304732A (en) | 1984-03-06 | 1994-04-19 | Mgi Pharma, Inc. | Herbicide resistance in plants |
| BR8600161A (pt) | 1985-01-18 | 1986-09-23 | Plant Genetic Systems Nv | Gene quimerico,vetores de plasmidio hibrido,intermediario,processo para controlar insetos em agricultura ou horticultura,composicao inseticida,processo para transformar celulas de plantas para expressar uma toxina de polipeptideo produzida por bacillus thuringiensis,planta,semente de planta,cultura de celulas e plasmidio |
| DE3545319A1 (de) | 1985-12-20 | 1987-06-25 | Basf Ag | Acrylsaeureester und fungizide, die diese verbindungen enthalten |
| DE3765449D1 (de) | 1986-03-11 | 1990-11-15 | Plant Genetic Systems Nv | Durch gentechnologie erhaltene und gegen glutaminsynthetase-inhibitoren resistente pflanzenzellen. |
| MY100846A (en) | 1986-05-02 | 1991-03-15 | Stauffer Chemical Co | Fungicidal pyridyl imidates |
| ES2011602T3 (es) | 1986-08-12 | 1994-07-16 | Mitsubishi Chem Ind | Derivados de piridinacarboxamida y su uso como fungicidas. |
| FR2629098B1 (fr) | 1988-03-23 | 1990-08-10 | Rhone Poulenc Agrochimie | Gene chimerique de resistance herbicide |
| US5180587A (en) | 1988-06-28 | 1993-01-19 | E. I. Du Pont De Nemours And Company | Tablet formulations of pesticides |
| CA2005658A1 (en) | 1988-12-19 | 1990-06-19 | Eliahu Zlotkin | Insecticidal toxins, genes encoding these toxins, antibodies binding to them and transgenic plant cells and plants expressing these toxins |
| ATE241699T1 (de) | 1989-03-24 | 2003-06-15 | Syngenta Participations Ag | Krankheitsresistente transgene pflanze |
| ATE174755T1 (de) | 1989-08-30 | 1999-01-15 | Aeci Ltd | Dosierungsmittel und dessen verwendung |
| DE69018772T2 (de) | 1989-11-07 | 1996-03-14 | Pioneer Hi Bred Int | Larven abtötende Lektine und darauf beruhende Pflanzenresistenz gegen Insekten. |
| US6187773B1 (en) | 1989-11-10 | 2001-02-13 | Agro-Kanesho Co., Ltd. | Hexahydrotriazine compounds and insecticides |
| JPH0747582B2 (ja) | 1989-12-11 | 1995-05-24 | 杏林製薬株式会社 | キナゾリン―３―アルカン酸誘導体とその塩およびその製造法 |
| US5372989A (en) | 1990-03-12 | 1994-12-13 | E. I. Du Pont De Nemours And Company | Water-dispersible or water-soluble pesticide grandules from heat-activated binders |
| JP3173784B2 (ja) | 1990-06-25 | 2001-06-04 | モンサント カンパニー | グリホセート耐性植物 |
| ES2091878T3 (es) | 1990-10-11 | 1996-11-16 | Sumitomo Chemical Co | Composicion plaguicida. |
| JP2828186B2 (ja) | 1991-09-13 | 1998-11-25 | 宇部興産株式会社 | アクリレート系化合物、その製法及び殺菌剤 |
| UA48104C2 (uk) | 1991-10-04 | 2002-08-15 | Новартіс Аг | Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника |
| US6069298A (en) | 1993-02-05 | 2000-05-30 | Regents Of The University Of Minnesota | Methods and an acetyl CoA carboxylase gene for conferring herbicide tolerance and an alteration in oil content of plants |
| US6303181B1 (en) | 1993-05-17 | 2001-10-16 | Electrochemicals Inc. | Direct metallization process employing a cationic conditioner and a binder |
| DE4322211A1 (de) | 1993-07-03 | 1995-01-12 | Basf Ag | Wäßrige, mehrphasige, stabile Fertigformulierung für Pflanzenschutz-Wirkstoffe und Verfahren zu ihrer Herstellung |
| US5530195A (en) | 1994-06-10 | 1996-06-25 | Ciba-Geigy Corporation | Bacillus thuringiensis gene encoding a toxin active against insects |
| US5773704A (en) | 1996-04-29 | 1998-06-30 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Herbicide resistant rice |
| DK0960190T3 (da) | 1996-07-17 | 2007-02-19 | Univ Michigan State | Imidazolinonherbicid-resistente sukkerroeplanter |
| US5773702A (en) | 1996-07-17 | 1998-06-30 | Board Of Trustees Operating Michigan State University | Imidazolinone herbicide resistant sugar beet plants |
| DE19650197A1 (de) | 1996-12-04 | 1998-06-10 | Bayer Ag | 3-Thiocarbamoylpyrazol-Derivate |
| TW460476B (en) | 1997-04-14 | 2001-10-21 | American Cyanamid Co | Fungicidal trifluoromethylalkylamino-triazolopyrimidines |
| DK1017670T3 (da) | 1997-09-18 | 2002-12-16 | Basf Ag | Benzamidoximderivater, mellemprodukter og fremgangsmåder til deres fremstilling og deres anvendelse som fungicider |
| DE19750012A1 (de) | 1997-11-12 | 1999-05-20 | Bayer Ag | Isothiazolcarbonsäureamide |
| EP1035772A4 (en) | 1997-12-04 | 2001-03-28 | Dow Agrosciences Llc | FUNGICIDAL COMPOSITIONS AND METHODS, AND COMPOUNDS AND METHODS FOR THEIR PRODUCTION |
| GB9817623D0 (en) | 1998-08-13 | 1998-10-07 | Glaxo Group Ltd | Pharmaceutical compounds |
| US6348643B1 (en) | 1998-10-29 | 2002-02-19 | American Cyanamid Company | DNA sequences encoding the arabidopsis acetohydroxy-acid synthase small subunit and methods of use |
| ATE305465T1 (de) | 1998-11-17 | 2005-10-15 | Kumiai Chemical Industry Co | Pyrimidinylbenzimidazol- und triazinylbenzimidazol-derivate und agrikulte/hortikulte fungizide |
| IT1303800B1 (it) | 1998-11-30 | 2001-02-23 | Isagro Ricerca Srl | Composti dipeptidici aventi elevata attivita' fungicida e loroutilizzo agronomico. |
| JP3417862B2 (ja) | 1999-02-02 | 2003-06-16 | 新東工業株式会社 | 酸化チタン光触媒高担持シリカゲルおよびその製造方法 |
| AU770077B2 (en) | 1999-03-11 | 2004-02-12 | Dow Agrosciences Llc | Heterocyclic substituted isoxazolidines and their use as fungicides |
| US6586617B1 (en) | 1999-04-28 | 2003-07-01 | Sumitomo Chemical Takeda Agro Company, Limited | Sulfonamide derivatives |
| UA73307C2 (uk) | 1999-08-05 | 2005-07-15 | Куміаі Кемікал Індастрі Ко., Лтд. | Похідна карбамату і фунгіцид сільськогосподарського/садівницького призначення |
| DE10021412A1 (de) | 1999-12-13 | 2001-06-21 | Bayer Ag | Fungizide Wirkstoffkombinationen |
| PL202070B1 (pl) | 2000-01-25 | 2009-05-29 | Syngenta Participations Ag | Selektywna kompozycja herbicydowa i sposób zwalczania rozwoju niepożądanych roślin w uprawach roślin użytkowych |
| US6376548B1 (en) | 2000-01-28 | 2002-04-23 | Rohm And Haas Company | Enhanced propertied pesticides |
| IL167956A (en) | 2000-02-04 | 2009-02-11 | Sumitomo Chemical Co | Isocyanate compounds |
| EP1284597A4 (en) | 2000-04-28 | 2005-12-28 | Basf Ag | USE OF A MUTANT BUTTERHOUSE AHAS 2 GENE AND IMIDAZOLINONE HERBICIDES FOR THE SELECTION OF TRANSGENIC MONOCOTYLEDONES, IMIDAZOLINONE HERBICIDE-RESISTANT CORN-RESISTANT MAIZE, RICE AND WHEAT PLANTS |
| BR0113500A (pt) | 2000-08-25 | 2003-07-01 | Syngenta Participations Ag | Toxinas inseticidas derivadas de proteìnas de cristais inseticidas de bacillus thuringiensis |
| RU2003110962A (ru) | 2000-09-18 | 2004-10-20 | Е.И.Дюпон де Немур энд Компани (US) | Пиридиниламиды и имиды для использования в качестве фунгицидов |
| ZA200303819B (en) | 2000-11-17 | 2004-05-17 | Dow Agrosciences Llc | Compounds having fungicidal activity and processes to make and use same. |
| US6548738B2 (en) | 2000-12-26 | 2003-04-15 | Research Development Foundation | ACC2-knockout mice and uses thereof |
| JP5034142B2 (ja) | 2001-04-20 | 2012-09-26 | 住友化学株式会社 | 植物病害防除剤組成物 |
| DE10136065A1 (de) | 2001-07-25 | 2003-02-13 | Bayer Cropscience Ag | Pyrazolylcarboxanilide |
| AR037228A1 (es) | 2001-07-30 | 2004-11-03 | Dow Agrosciences Llc | Compuestos del acido 6-(aril o heteroaril)-4-aminopicolinico, composicion herbicida que los comprende y metodo para controlar vegetacion no deseada |
| FR2828196A1 (fr) | 2001-08-03 | 2003-02-07 | Aventis Cropscience Sa | Derives de chromone a action fongicide, procede de preparation et application dans le domaine de l'agriculture |
| ES2377623T3 (es) | 2001-08-09 | 2012-03-29 | University Of Saskatchewan | Plantas de trigo con resistencia incrementada a herbicidas de imidazolinona. |
| BR0211809A (pt) | 2001-08-09 | 2004-09-08 | Univ Saskatchewan | Plantas de trigo tendo resistência aumentada a herbicidas de imidazolinona e método de produção da mesma |
| MXPA04001056A (es) | 2001-08-09 | 2005-02-17 | Northwest Plant Breeding Compa | Plantas de trigo que tienen resistencia incrementada a los herbicidas de imidazolinona. |
| EP1426365B9 (en) | 2001-08-17 | 2009-10-21 | Mitsui Chemicals Agro, Inc. | 3-phenoxy-4-pyridazinol derivative and herbicide composition containing the same |
| US7230167B2 (en) | 2001-08-31 | 2007-06-12 | Syngenta Participations Ag | Modified Cry3A toxins and nucleic acid sequences coding therefor |
| US6977300B2 (en) * | 2001-11-09 | 2005-12-20 | Cv Therapeutics, Inc. | A2B adenosine receptor antagonists |
| US7304070B2 (en) | 2001-11-09 | 2007-12-04 | Cv Therapeutics, Inc. | A2B adenosine receptor antagonists |
| WO2003052073A2 (en) | 2001-12-17 | 2003-06-26 | Syngenta Participations Ag | Novel corn event |
| AU2002354251A1 (en) | 2001-12-21 | 2003-07-09 | Nissan Chemical Industries, Ltd. | Bactericidal composition |
| TWI327462B (en) | 2002-01-18 | 2010-07-21 | Sumitomo Chemical Co | Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same |
| DE10204390A1 (de) | 2002-02-04 | 2003-08-14 | Bayer Cropscience Ag | Disubstituierte Thiazolylcarboxanilide |
| HK1079785B (zh) | 2002-03-05 | 2007-08-10 | 辛根塔参与股份公司 | 邻环丙基-n-甲酰苯胺及其作为杀菌剂的用途 |
| KR100985160B1 (ko) * | 2002-06-06 | 2010-10-05 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 신규한 축합된 이미다졸 유도체 |
| CA2492167C (en) | 2002-07-10 | 2015-06-16 | The Department Of Agriculture, Western Australia | Wheat plants having increased resistance to imidazolinone herbicides |
| GB0227966D0 (en) | 2002-11-29 | 2003-01-08 | Syngenta Participations Ag | Organic Compounds |
| EP1585392B1 (en) | 2003-01-06 | 2009-03-18 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Herbicides inhibiting the action of plant acetyl-coa carboxylase for use as pesticides. |
| WO2004083193A1 (ja) | 2003-03-17 | 2004-09-30 | Sumitomo Chemical Company, Limited | アミド化合物およびこれを含有する殺菌剤組成物 |
| US7423031B2 (en) | 2003-05-01 | 2008-09-09 | Irm Llc | Compounds and compositions as protein kinase inhibitors |
| AU2004243416B2 (en) | 2003-05-28 | 2009-06-11 | Basf Se | Wheat plants having increased tolerance to imidazolinone herbicides |
| AU2004265250C1 (en) | 2003-06-23 | 2008-05-01 | Pioneer Hi-Bred International, Inc. | Engineering single-gene-controlled staygreen potential into plants |
| EP2982240B1 (en) | 2003-08-29 | 2019-07-31 | Instituto Nacional de Tecnologia Agropecuaria | Rice plants having increased tolerance to imidazolinone herbicides |
| TWI355894B (en) | 2003-12-19 | 2012-01-11 | Du Pont | Herbicidal pyrimidines |
| HRP20100538T1 (hr) | 2004-03-10 | 2010-12-31 | Basf Se | 5,6-dialkil-7-aminotriazolopirimidini, postupci za njihovo dobijanje, njihova primjena za kontrolu patogenih gljiva, kao i sredstva koja sadrže spomenute spojeve |
| NZ549202A (en) | 2004-03-10 | 2009-05-31 | Basf Ag | 5,6-Dialkyl-7-amino-triazolopyrimidines, methods for their production, their use for controlling pathogenic fungi and agents containing said compounds |
| US20080020999A1 (en) | 2004-06-03 | 2008-01-24 | Klapproth Michael C | Fungicidal Mixtures Of Amidinylphenyl Compounds |
| JP2008502636A (ja) | 2004-06-18 | 2008-01-31 | ビーエーエスエフ アクチェンゲゼルシャフト | Ｎ−（オルト−フェニル）−１−メチル−３−ジフルオロメチルピラゾール−４−カルボキシアニリドおよびそれらの殺菌剤としての使用 |
| ATE458722T1 (de) | 2004-06-18 | 2010-03-15 | Basf Se | 1-methyl-3-trifluormethyl-pyrazol-4-carbonsäure (ortho-phenyl)-anilide und ihre verwendung als fungizid |
| US7947691B2 (en) * | 2004-07-21 | 2011-05-24 | Athersys, Inc. | Cyclic n-hydroxy imides as inhibitors of flap endonuclease and uses thereof |
| GB0418048D0 (en) | 2004-08-12 | 2004-09-15 | Syngenta Participations Ag | Method for protecting useful plants or plant propagation material |
| DE102005007160A1 (de) | 2005-02-16 | 2006-08-24 | Basf Ag | Pyrazolcarbonsäureanilide, Verfahren zu ihrer Herstellung und sie enthaltende Mittel zur Bekämpfung von Schadpilzen |
| EP1853608B1 (de) | 2005-02-16 | 2008-07-09 | Basf Se | 5-alkoxyalkyl-6-alkyl-7-amino-azolopyrimidine, verfahren zu ihrer herstellung und ihre verwendung zur bekämpfung von schadpilzen sowie sie enthaltende mittel |
| DE102005009458A1 (de) | 2005-03-02 | 2006-09-07 | Bayer Cropscience Ag | Pyrazolylcarboxanilide |
| EA014556B1 (ru) | 2005-08-10 | 2010-12-30 | ГЛЭКСОСМИТКЛАЙН ЭлЭлСи | Производные ксантина в качестве селективных агонистов hm74a |
| MY143535A (en) | 2006-01-13 | 2011-05-31 | Dow Agrosciences Llc | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides |
| WO2007090624A2 (en) | 2006-02-09 | 2007-08-16 | Syngenta Participations Ag | A method of protecting a plant propagation material, a plant, and/or plant organs |
| CA2644996A1 (en) * | 2006-03-02 | 2007-09-13 | Cv Therapeutics, Inc. | A2a adenosine receptor antagonists |
| US8247414B2 (en) * | 2006-07-25 | 2012-08-21 | Cephalon, Inc. | Pyridizinone derivatives and the use thereof as H3 inhibitors |
| AR063417A1 (es) | 2006-11-01 | 2009-01-28 | Astrazeneca Ab | Compuestos inhibidores del activador de plasminogeno tipo 1(pai-1) |
| AU2008256717B2 (en) | 2007-05-25 | 2013-11-21 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator |
| CN101481380B (zh) * | 2008-01-08 | 2012-10-17 | 浙江医药股份有限公司新昌制药厂 | 噻吩并哒嗪类化合物及其制备方法、药物组合物及其用途 |
| CA2729656A1 (en) | 2008-07-02 | 2010-01-07 | Avexa Limited | Imidazopyrimidinones and uses thereof |
| US20110244059A1 (en) | 2008-08-20 | 2011-10-06 | The University Of Medicine And Dentistry Of New Jersey | Inhibiting obesity progression by inhibiting adipocyte differentiation with a pre-adipocyte autophagy inhibitor |
| EP2351743A4 (en) * | 2008-10-27 | 2012-05-09 | Takeda Pharmaceutical | BICYCLIC COMPOUND |
| US20100113473A1 (en) | 2008-10-30 | 2010-05-06 | Player Mark R | Aryl amide compound as an acetyl coenzyme a carboxylase inhibitor |
| US20100280067A1 (en) | 2009-04-30 | 2010-11-04 | Pakala Kumara Savithru Sarma | Inhibitors of acetyl-coa carboxylase |
| UY33756A (es) | 2010-11-30 | 2012-06-29 | Takeda Pharmaceutical | Compuesto biciclico |
| US20130116241A1 (en) * | 2011-11-09 | 2013-05-09 | Abbvie Inc. | Novel inhibitor compounds of phosphodiesterase type 10a |
| TWI701253B (zh) | 2011-11-11 | 2020-08-11 | 美商基利阿波羅有限責任公司 | Ａｃｃ抑制劑及彼等之用途 |
| EP2994141A4 (en) | 2013-05-10 | 2016-11-23 | Nimbus Apollo Inc | ACC-HEMMER AND USES THEREOF |
| HK1221661A1 (zh) | 2013-05-10 | 2017-06-09 | Gilead Apollo, Llc | Acc抑制剂和其用途 |
| CN105358152A (zh) | 2013-05-10 | 2016-02-24 | 尼普斯阿波罗有限公司 | Acc抑制剂和其用途 |
-
2014
- 2014-05-08 EA EA201591961A patent/EA030958B1/ru not_active IP Right Cessation
- 2014-05-08 KR KR1020157035035A patent/KR20160005364A/ko not_active Withdrawn
- 2014-05-08 AU AU2014262546A patent/AU2014262546B2/en not_active Ceased
- 2014-05-08 HK HK16109918.2A patent/HK1221660A1/zh unknown
- 2014-05-08 CN CN201480036138.5A patent/CN105358143B/zh not_active Expired - Fee Related
- 2014-05-08 JP JP2016513085A patent/JP6417402B2/ja not_active Expired - Fee Related
- 2014-05-08 BR BR112015028173A patent/BR112015028173A2/pt not_active Application Discontinuation
- 2014-05-08 HK HK16109661.1A patent/HK1221419A1/zh unknown
- 2014-05-08 EP EP14794603.2A patent/EP2994128B1/en not_active Not-in-force
- 2014-05-08 US US14/890,344 patent/US9765089B2/en not_active Expired - Fee Related
- 2014-05-08 WO PCT/US2014/037368 patent/WO2014182950A1/en not_active Ceased
- 2014-05-08 CA CA2911818A patent/CA2911818A1/en not_active Abandoned
- 2014-05-08 MX MX2015015421A patent/MX2015015421A/es unknown
- 2014-05-09 AR ARP140101890A patent/AR096243A1/es unknown
-
2015
- 2015-11-10 CL CL2015003316A patent/CL2015003316A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2015015421A (es) | 2016-06-21 |
| KR20160005364A (ko) | 2016-01-14 |
| CN105358143B (zh) | 2019-01-22 |
| JP6417402B2 (ja) | 2018-11-07 |
| EA030958B1 (ru) | 2018-10-31 |
| WO2014182950A1 (en) | 2014-11-13 |
| US20160185799A1 (en) | 2016-06-30 |
| JP2016520064A (ja) | 2016-07-11 |
| AU2014262546B2 (en) | 2018-11-08 |
| EP2994128A1 (en) | 2016-03-16 |
| EA201591961A1 (ru) | 2016-06-30 |
| CN105358143A (zh) | 2016-02-24 |
| CL2015003316A1 (es) | 2016-07-29 |
| CA2911818A1 (en) | 2014-11-13 |
| EP2994128A4 (en) | 2016-11-23 |
| BR112015028173A2 (pt) | 2017-07-25 |
| US9765089B2 (en) | 2017-09-19 |
| AU2014262546A1 (en) | 2015-11-26 |
| HK1221660A1 (zh) | 2017-06-09 |
| HK1221419A1 (zh) | 2017-06-02 |
| EP2994128B1 (en) | 2019-01-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR096243A1 (es) | Inhibidores de acc y usos de los mismos | |
| AR096241A1 (es) | Inhibidores de acc y usos de los mismos | |
| AR096242A1 (es) | Inhibidores de acc y usos de los mismos | |
| AR106798A1 (es) | Inhibidores pirazol de acc y usos de los mismos | |
| AR106806A1 (es) | Inhibidores triazol de acc y usos de los mismos | |
| AR106799A1 (es) | Inhibidores éster de acc y usos de los mismos | |
| AR114236A1 (es) | Inhibidores de la gcn2 y usos de los mismos | |
| AR102177A1 (es) | Compuestos de heteroarilo como inhibidores de btk y usos de los mismos | |
| AR098721A1 (es) | Inhibidores de biarilo de tirosina quinasa de bruton | |
| AR096837A1 (es) | Heterociclos tricíclicos como inhibidores de proteínas bet | |
| AR106472A1 (es) | Inhibidores de acc y usos de los mismos | |
| AR095326A1 (es) | Heterociclos tricíclicos como inhibidores de la proteína bet | |
| AR098136A1 (es) | Compuestos de heteroarilo como inhibidores de btk y usos de los mismos | |
| AR100809A1 (es) | Inhibidores de fosfatidilinositol 3-quinasa | |
| AR114235A1 (es) | Inhibidores de gcn2 y usos de los mismos | |
| AR096979A1 (es) | Derivados de pirrol, su procedimiento de preparación y las composiciones farmacéuticas que los contienen | |
| AR098337A1 (es) | Triazolopirazina | |
| AR097082A1 (es) | Compuestos terapéuticamente activos y sus métodos de uso | |
| AR100975A1 (es) | Inhibidores de fosfatidilinositol 3-quinasa | |
| AR104025A1 (es) | Carbamatos de piperazina como moduladores de magl y/o abhd6, procesos para su preparación y composiciones farmacéuticas | |
| AR095339A1 (es) | Compuestos moduladores alostericos de la hemoglobina | |
| AR103170A1 (es) | Compuestos y composiciones farmacéuticas de los mismos para el tratamiento de desordenes inflamatorios y osteoartritis | |
| AR092306A1 (es) | Antibacterianos de fenicol | |
| AR090572A1 (es) | Derivados de tienopirimidina, procesos para su preparacion y sus usos terapeuticos | |
| AR114496A1 (es) | Compuestos antiproliferación y usos de los mismos |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |