CL2015003316A1 - Inhibidores de acc y usos de los mismos. - Google Patents
Inhibidores de acc y usos de los mismos.Info
- Publication number
- CL2015003316A1 CL2015003316A1 CL2015003316A CL2015003316A CL2015003316A1 CL 2015003316 A1 CL2015003316 A1 CL 2015003316A1 CL 2015003316 A CL2015003316 A CL 2015003316A CL 2015003316 A CL2015003316 A CL 2015003316A CL 2015003316 A1 CL2015003316 A1 CL 2015003316A1
- Authority
- CL
- Chile
- Prior art keywords
- acc inhibitors
- acc
- inhibitors
- treat
- acetil
- Prior art date
Links
- 229940121373 acetyl-coa carboxylase inhibitor Drugs 0.000 title 1
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 208000030159 metabolic disease Diseases 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Zoology (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epidemiology (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361821829P | 2013-05-10 | 2013-05-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2015003316A1 true CL2015003316A1 (es) | 2016-07-29 |
Family
ID=51867754
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2015003316A CL2015003316A1 (es) | 2013-05-10 | 2015-11-10 | Inhibidores de acc y usos de los mismos. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9765089B2 (enExample) |
| EP (1) | EP2994128B1 (enExample) |
| JP (1) | JP6417402B2 (enExample) |
| KR (1) | KR20160005364A (enExample) |
| CN (1) | CN105358143B (enExample) |
| AR (1) | AR096243A1 (enExample) |
| AU (1) | AU2014262546B2 (enExample) |
| BR (1) | BR112015028173A2 (enExample) |
| CA (1) | CA2911818A1 (enExample) |
| CL (1) | CL2015003316A1 (enExample) |
| EA (1) | EA030958B1 (enExample) |
| HK (2) | HK1221660A1 (enExample) |
| MX (1) | MX2015015421A (enExample) |
| WO (1) | WO2014182950A1 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105358152A (zh) * | 2013-05-10 | 2016-02-24 | 尼普斯阿波罗有限公司 | Acc抑制剂和其用途 |
| EP2994141A4 (en) | 2013-05-10 | 2016-11-23 | Nimbus Apollo Inc | ACC-HEMMER AND USES THEREOF |
| HK1221661A1 (zh) | 2013-05-10 | 2017-06-09 | Gilead Apollo, Llc | Acc抑制剂和其用途 |
| US10150728B2 (en) | 2013-10-17 | 2018-12-11 | Shionogi & Co., Ltd. | Alkylene derivatives |
| US10202361B2 (en) | 2014-08-29 | 2019-02-12 | Fmc Corporation | Pyridazinones as herbicides |
| CN107106873A (zh) | 2015-01-09 | 2017-08-29 | 吉利德阿波罗公司 | 用于治疗非酒精性脂肪肝病的acc抑制剂组合治疗 |
| UY36586A (es) | 2015-03-26 | 2016-10-31 | Bayer Pharma AG | Heterociclilmetiltienouracilos y uso de los mismos |
| GB201512286D0 (en) * | 2015-07-14 | 2015-08-19 | F2G Ltd | Chemical compounds |
| AR106472A1 (es) * | 2015-10-26 | 2018-01-17 | Gilead Apollo Llc | Inhibidores de acc y usos de los mismos |
| US20170166583A1 (en) | 2015-11-25 | 2017-06-15 | Gilead Apollo, Llc | Ester acc inhibitors and uses thereof |
| EP3380480B1 (en) * | 2015-11-25 | 2022-12-14 | Gilead Apollo, LLC | Pyrazole acc inhibitors and uses thereof |
| BR112018009212B1 (pt) | 2015-11-25 | 2022-06-14 | Gilead Apollo, Llc | Método para controlar patógenos fúngicos agrícolas |
| WO2017091617A1 (en) * | 2015-11-25 | 2017-06-01 | Gilead Apollo, Llc | Triazole acc inhibitors and uses thereof |
| WO2017100703A1 (en) * | 2015-12-10 | 2017-06-15 | Colin Combs | Ems analogues of lyn/src-tyrosine kinase inhibitors |
| US10183951B2 (en) | 2016-03-02 | 2019-01-22 | Gilead Apollo, Llc | Solid forms of a thienopyrimidinedione ACC inhibitor and methods for production thereof |
| WO2018041771A1 (de) | 2016-09-02 | 2018-03-08 | Bayer Pharma Aktiengesellschaft | (1-methylcyclopropyl)methyl-substituierte thienouracile und ihre verwendung |
| KR20190053242A (ko) | 2016-09-23 | 2019-05-17 | 바이엘 악티엔게젤샤프트 | N3-시클릭 치환된 티에노우라실 및 그의 용도 |
| WO2018133858A1 (en) | 2017-01-22 | 2018-07-26 | Sunshine Lake Pharma Co., Ltd. | Thienopyrimidine derivative and use thereof in medicine |
| CN110431143B (zh) * | 2017-03-24 | 2022-08-12 | 浙江海正药业股份有限公司 | 杂芳基并嘧啶酮类衍生物及其制备方法和用途 |
| CN110431144B (zh) * | 2017-03-24 | 2022-08-05 | 浙江海正药业股份有限公司 | 氰基取代的杂芳基并嘧啶酮类衍生物及其制备方法和用途 |
| JP6906626B2 (ja) | 2017-03-28 | 2021-07-21 | ギリアード サイエンシーズ, インコーポレイテッド | 肝疾患を処置するための治療的組み合わせ |
| CN111050750B (zh) | 2017-08-24 | 2024-09-24 | 诺和诺德股份有限公司 | Glp-1组合物及其用途 |
| KR20190036705A (ko) | 2017-09-28 | 2019-04-05 | 한미약품 주식회사 | (2r)-2-(2-메톡시페닐)-2-(옥산-4-일옥시)에탄-1-올 화합물의 신규 제조방법 및 이에 사용되는 중간체 |
| WO2019233443A1 (zh) | 2018-06-05 | 2019-12-12 | 南京明德新药研发有限公司 | 噻吩并[2,3-c]哒嗪-4(1H)-酮类衍生物及其应用 |
| US12428432B2 (en) | 2019-07-02 | 2025-09-30 | Sunshine Lake Pharma Co., Ltd. | Thienopyrimidine derivatives having stereo configurations and use thereof in medicine |
| AR119594A1 (es) | 2019-08-09 | 2021-12-29 | Gilead Sciences Inc | Derivados de tienopirimidina como inhibidores acc y usos de los mismos |
| US11673899B2 (en) * | 2019-12-05 | 2023-06-13 | Zhangzhou Pien Tze Huang Pharmaceutical Co., Ltd. | Crystal form of thieno[2,3-c]pyridazine-4(1H)-one compound, preparation method therefor and use thereof |
| WO2021112213A1 (ja) * | 2019-12-05 | 2021-06-10 | 日本曹達株式会社 | 2,4-ジオキソ-1,4-ジヒドロチエノピリミジン化合物、及びそれを含有する農園芸用殺菌剤又は医療用・動物用抗真菌剤 |
| JP7761567B2 (ja) | 2020-02-18 | 2025-10-28 | ノヴォ ノルディスク アー/エス | 医薬製剤 |
| US11478533B2 (en) | 2020-04-27 | 2022-10-25 | Novo Nordisk A/S | Semaglutide for use in medicine |
| US20250082765A1 (en) * | 2021-07-26 | 2025-03-13 | Rao Dr Boggarapu Prakash | Molecules as anticancer agents for targeted treatment of breast and prostate cancer |
| WO2024089216A1 (en) | 2022-10-27 | 2024-05-02 | Syngenta Crop Protection Ag | Novel sulfur-containing heteroaryl carboxamide compounds |
| US12303604B1 (en) | 2024-10-16 | 2025-05-20 | Currax Pharmaceuticals Llc | Pharmaceutical formulations comprising naltrexone and/or bupropion |
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-
2014
- 2014-05-08 EA EA201591961A patent/EA030958B1/ru not_active IP Right Cessation
- 2014-05-08 KR KR1020157035035A patent/KR20160005364A/ko not_active Withdrawn
- 2014-05-08 AU AU2014262546A patent/AU2014262546B2/en not_active Ceased
- 2014-05-08 HK HK16109918.2A patent/HK1221660A1/zh unknown
- 2014-05-08 CN CN201480036138.5A patent/CN105358143B/zh not_active Expired - Fee Related
- 2014-05-08 JP JP2016513085A patent/JP6417402B2/ja not_active Expired - Fee Related
- 2014-05-08 BR BR112015028173A patent/BR112015028173A2/pt not_active Application Discontinuation
- 2014-05-08 HK HK16109661.1A patent/HK1221419A1/zh unknown
- 2014-05-08 EP EP14794603.2A patent/EP2994128B1/en not_active Not-in-force
- 2014-05-08 US US14/890,344 patent/US9765089B2/en not_active Expired - Fee Related
- 2014-05-08 WO PCT/US2014/037368 patent/WO2014182950A1/en not_active Ceased
- 2014-05-08 CA CA2911818A patent/CA2911818A1/en not_active Abandoned
- 2014-05-08 MX MX2015015421A patent/MX2015015421A/es unknown
- 2014-05-09 AR ARP140101890A patent/AR096243A1/es unknown
-
2015
- 2015-11-10 CL CL2015003316A patent/CL2015003316A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2015015421A (es) | 2016-06-21 |
| KR20160005364A (ko) | 2016-01-14 |
| CN105358143B (zh) | 2019-01-22 |
| JP6417402B2 (ja) | 2018-11-07 |
| EA030958B1 (ru) | 2018-10-31 |
| WO2014182950A1 (en) | 2014-11-13 |
| US20160185799A1 (en) | 2016-06-30 |
| JP2016520064A (ja) | 2016-07-11 |
| AU2014262546B2 (en) | 2018-11-08 |
| EP2994128A1 (en) | 2016-03-16 |
| EA201591961A1 (ru) | 2016-06-30 |
| CN105358143A (zh) | 2016-02-24 |
| CA2911818A1 (en) | 2014-11-13 |
| EP2994128A4 (en) | 2016-11-23 |
| BR112015028173A2 (pt) | 2017-07-25 |
| US9765089B2 (en) | 2017-09-19 |
| AU2014262546A1 (en) | 2015-11-26 |
| HK1221660A1 (zh) | 2017-06-09 |
| HK1221419A1 (zh) | 2017-06-02 |
| EP2994128B1 (en) | 2019-01-30 |
| AR096243A1 (es) | 2015-12-16 |
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