AR077487A2 - Composiciones atenuadas para dialisis - Google Patents
Composiciones atenuadas para dialisisInfo
- Publication number
- AR077487A2 AR077487A2 ARP100102606A ARP100102606A AR077487A2 AR 077487 A2 AR077487 A2 AR 077487A2 AR P100102606 A ARP100102606 A AR P100102606A AR P100102606 A ARP100102606 A AR P100102606A AR 077487 A2 AR077487 A2 AR 077487A2
- Authority
- AR
- Argentina
- Prior art keywords
- citrate
- acetate
- lactate
- precursor composition
- magnesium
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- External Artificial Organs (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Los concentrados de acido, y las composiciones dialiticas de esos, contienen ácido cítrico y una cantidad efectiva de un agente atenuante, seleccionado entre acetato y/o Iactato. El agente atenuante permite una cantidad fisiologicamente aceptable de citrato para mantener el pH deseado de dialitico. Reivindicacion 1: Una composicion precursora para preparar un dialitico atenuado, la composicion precursora comprendiendo de citrato en una concentracion que varia desde alrededor de 20 a alrededor de 900 mEq/L; un atenuante; agua; cloruro en una concentracion que varia desde alrededor de 1.000 a alrededor de 7.000 nEq/L; y al menos un cation fisiologicamente aceptable. Reivindicacion 9: La composicion precursora de las reivindicaciones 1-8, que además comprende de un azucar seleccionado de la glucosa, una poli(glucosa), y fructosa, en una concentracion de menos de alrededor de 2.700 g/L. Reivindicacion 10: La composicion precursora de las reivindicaciones 1-9, en la cual el citrato está en la forma de al menos un ácido cítrico y una sal de ese, seleccionados de un grupo que consiste de citrato de sodio bihidrato, citrato de hidrogeno disodio, citrato trisodio, citrato bihidrato trisodio, citrato de potasio bihidrato, citrato de hidrogeno bipotasio, citrato de calcio, y citrato de magnesio; en donde el acetato de anion atenuante está en la forma de al menos un ácido acético y una sal de ese, seleccionados de un grupo que consiste de acetato de sodio, acetato de sodio trihidrato, acetato de potasio, acetato de calcio, acetato de calcio monohidrato, acetato de magnesio, y acetato de magnesio tetrahidrato; y en donde el lactato del anion atenuante está en la forma de al menos un ácido láctico y una sal de ese, seleccionados de un grupo que consiste de lactato de sodio, lactato de potasio, lactato de calcio y lactato de magnesio trihidrato.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10504998P | 1998-10-20 | 1998-10-20 | |
| US17606398A | 1998-10-20 | 1998-10-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR077487A2 true AR077487A2 (es) | 2011-08-31 |
Family
ID=26802194
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP990105299A AR020918A1 (es) | 1998-10-20 | 1999-10-20 | Composiciones atenuadas para dialisis |
| ARP100102606A AR077487A2 (es) | 1998-10-20 | 2010-07-16 | Composiciones atenuadas para dialisis |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP990105299A AR020918A1 (es) | 1998-10-20 | 1999-10-20 | Composiciones atenuadas para dialisis |
Country Status (22)
| Country | Link |
|---|---|
| EP (3) | EP1721606B1 (es) |
| JP (3) | JP4932084B2 (es) |
| CN (1) | CN1188136C (es) |
| AR (2) | AR020918A1 (es) |
| AT (1) | ATE321563T1 (es) |
| AU (1) | AU765029B2 (es) |
| BR (1) | BR9914644A (es) |
| CA (1) | CA2347447C (es) |
| CO (1) | CO5160318A1 (es) |
| CY (1) | CY1107496T1 (es) |
| DE (2) | DE69930676T3 (es) |
| DK (2) | DK1721606T3 (es) |
| EG (1) | EG24303A (es) |
| ES (2) | ES2262363T5 (es) |
| HK (1) | HK1097466A1 (es) |
| IL (2) | IL142648A0 (es) |
| MX (1) | MXPA01003969A (es) |
| MY (1) | MY125622A (es) |
| NZ (1) | NZ511172A (es) |
| PT (2) | PT1721606E (es) |
| TW (1) | TWI240630B (es) |
| WO (1) | WO2000023086A2 (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7670491B2 (en) * | 1998-10-20 | 2010-03-02 | Advanced Renal Technologies | Buffered compositions for dialysis |
| WO2001021233A1 (en) * | 1999-09-22 | 2001-03-29 | Advanced Renal Technologies | High citrate dialysate and uses thereof |
| GR1003567B (el) * | 2000-06-28 | 2001-04-10 | Νεωτερα ενιαια και σταθερα αμινοξεων-διττανθρακικων πλεονεκτικα διαλυματα για την περιτοναικη καθαρση και αιμοκαθαρση. | |
| JP5204359B2 (ja) * | 2001-09-28 | 2013-06-05 | 味の素株式会社 | 透析用剤およびその製造方法 |
| US7053059B2 (en) * | 2003-07-25 | 2006-05-30 | Baxter International Inc. | Dialysis solutions with reduced levels of glucose degradation products |
| EP1890686B1 (en) * | 2005-05-30 | 2017-10-04 | Fresenius Medical Care Deutschland GmbH | Peritoneal dialysis fluid |
| JP5371278B2 (ja) * | 2008-04-03 | 2013-12-18 | エイワイファーマ株式会社 | 透析用剤およびその製造方法 |
| JP5560539B2 (ja) * | 2008-06-13 | 2014-07-30 | ニプロ株式会社 | 透析液調製装置 |
| ES2332636B1 (es) * | 2008-08-06 | 2011-02-10 | Universitat De Les Illes Balears | Composicion de liquido de dialisis. |
| AU2010262902B2 (en) | 2009-06-17 | 2013-05-02 | Fresenius Medical Care Holdings, Inc. | Methods of regional citrate anticoagulation dialysis |
| RU2438663C1 (ru) | 2010-10-18 | 2012-01-10 | Общество с ограниченной ответственностью "Научно-производственное объединение "Нефрон" (ООО "НПО "Нефрон") | Способ получения гемодиализирующего раствора для бикарбонатного гемодиализа |
| CH712274B1 (fr) * | 2016-03-18 | 2020-06-30 | Hemo Plus Sarl | Unité pour la préparation d'au moins une solution de concentrés pour hémodialyse et procédé de préparation de cette solution. |
| CN107281098A (zh) * | 2017-06-30 | 2017-10-24 | 华仁药业股份有限公司 | 一种血液滤过置换液 |
| CN107890568A (zh) * | 2017-10-31 | 2018-04-10 | 华仁药业股份有限公司 | 一种低危害的血液滤过置换液及其制备工艺 |
| CN112167264B (zh) * | 2020-10-28 | 2021-10-26 | 广州吾同生态科技有限公司 | 一种次氯酸电解液、次氯酸消毒液及其制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2929871A1 (de) | 1979-07-24 | 1981-01-29 | Gambro Dialysatoren | Waessriges konzentrat fuer dialyse-loesungen |
| US5252213A (en) | 1989-06-20 | 1993-10-12 | University Of Washington | Dry dialysate composition |
| EP0457960A3 (en) * | 1990-05-17 | 1993-01-07 | Minntech Corporation | High acid concentration dialysates |
| CA2098839C (en) * | 1990-12-18 | 2001-03-13 | Suhail Ahmad | Dialysate production system with dialysate pellets |
| DE4114908A1 (de) * | 1991-05-07 | 1992-11-12 | Klaus Dr Med Sodemann | Dialyseloesung zur dialysebehandlung, konzentrat und vorrichtung zur dialysebehandlung |
| EP0647130A1 (en) * | 1992-06-03 | 1995-04-12 | Minntech Corporation | Method of hemodialysis and hemodialysis liquids including hydrochloric acid |
| JP3398184B2 (ja) * | 1993-03-30 | 2003-04-21 | 味の素ファルマ株式会社 | 透析用剤 |
| DE69527923T2 (de) * | 1994-07-01 | 2003-04-24 | Baxter Int | Biochemisch isotone peritonealdialyselösungen |
| JP3530235B2 (ja) * | 1994-09-27 | 2004-05-24 | 味の素ファルマ株式会社 | 血液透析用剤 |
| DE19631124A1 (de) * | 1996-08-01 | 1998-02-05 | Fresenius Medical Care De Gmbh | Verfahren zur Herstellung einer Bicarbonat enthaltenden Infusions- oder Dialysierlösung |
| JP3619921B2 (ja) * | 1996-09-13 | 2005-02-16 | 富田製薬株式会社 | 重炭酸固形透析用剤 |
| DE19654746C2 (de) * | 1996-12-30 | 2000-05-11 | Klaus Sodemann | Dialyselösung |
-
1999
- 1999-10-18 EG EG129699A patent/EG24303A/xx active
- 1999-10-19 DK DK06006408.6T patent/DK1721606T3/da active
- 1999-10-19 EP EP06006408.6A patent/EP1721606B1/en not_active Expired - Lifetime
- 1999-10-19 AT AT99970600T patent/ATE321563T1/de active
- 1999-10-19 BR BR9914644-4A patent/BR9914644A/pt not_active Application Discontinuation
- 1999-10-19 DK DK99970600.5T patent/DK1124567T4/da active
- 1999-10-19 WO PCT/US1999/024583 patent/WO2000023086A2/en active IP Right Grant
- 1999-10-19 CA CA002347447A patent/CA2347447C/en not_active Expired - Lifetime
- 1999-10-19 EP EP20110190795 patent/EP2452685A1/en not_active Withdrawn
- 1999-10-19 MY MYPI99004515A patent/MY125622A/en unknown
- 1999-10-19 PT PT60064086T patent/PT1721606E/pt unknown
- 1999-10-19 DE DE69930676T patent/DE69930676T3/de not_active Expired - Lifetime
- 1999-10-19 EP EP99970600A patent/EP1124567B2/en not_active Expired - Lifetime
- 1999-10-19 PT PT99970600T patent/PT1124567E/pt unknown
- 1999-10-19 IL IL14264899A patent/IL142648A0/xx active IP Right Grant
- 1999-10-19 AU AU14481/00A patent/AU765029B2/en not_active Ceased
- 1999-10-19 CN CNB998135658A patent/CN1188136C/zh not_active Expired - Fee Related
- 1999-10-19 NZ NZ511172A patent/NZ511172A/xx not_active IP Right Cessation
- 1999-10-19 ES ES99970600T patent/ES2262363T5/es not_active Expired - Lifetime
- 1999-10-19 MX MXPA01003969A patent/MXPA01003969A/es active IP Right Grant
- 1999-10-19 ES ES06006408.6T patent/ES2438971T3/es not_active Expired - Lifetime
- 1999-10-19 DE DE69930676A patent/DE69930676D1/de not_active Expired - Lifetime
- 1999-10-19 JP JP2000576860A patent/JP4932084B2/ja not_active Expired - Lifetime
- 1999-10-20 AR ARP990105299A patent/AR020918A1/es active IP Right Grant
- 1999-10-20 CO CO99066230A patent/CO5160318A1/es unknown
- 1999-10-20 TW TW088118133A patent/TWI240630B/zh not_active IP Right Cessation
-
2001
- 2001-04-17 IL IL142648A patent/IL142648A/en not_active IP Right Cessation
-
2006
- 2006-06-22 CY CY20061100846T patent/CY1107496T1/el unknown
-
2007
- 2007-05-11 HK HK07105029.7A patent/HK1097466A1/xx not_active IP Right Cessation
-
2010
- 2010-07-16 AR ARP100102606A patent/AR077487A2/es unknown
-
2011
- 2011-10-19 JP JP2011229528A patent/JP2012066088A/ja active Pending
-
2013
- 2013-09-27 JP JP2013201021A patent/JP5975962B2/ja not_active Expired - Fee Related
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |