AR077473A2 - Uso de anticuerpos anti-tnf alfa y otro farmaco.metodo de tratamiento. composicion farmaceutica. conjunto de elementos - Google Patents

Uso de anticuerpos anti-tnf alfa y otro farmaco.metodo de tratamiento. composicion farmaceutica. conjunto de elementos

Info

Publication number
AR077473A2
AR077473A2 ARP100102558A ARP100102558A AR077473A2 AR 077473 A2 AR077473 A2 AR 077473A2 AR P100102558 A ARP100102558 A AR P100102558A AR P100102558 A ARP100102558 A AR P100102558A AR 077473 A2 AR077473 A2 AR 077473A2
Authority
AR
Argentina
Prior art keywords
pharmaceutical composition
combination
drug
clause
antibodies
Prior art date
Application number
ARP100102558A
Other languages
English (en)
Inventor
Steven Fischkoff
Elliot Chartash
Original Assignee
Abbott Biotech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29268783&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR077473(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Biotech Ltd filed Critical Abbott Biotech Ltd
Publication of AR077473A2 publication Critical patent/AR077473A2/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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Abstract

Método de tratamiento de trastornos en los cuales la actividad del TFN es nociva, por medio de una administracion bisemanal, subcutánea de anticuerpos humanos, preferentemente anticuerpos recombinantes humanos, que se unen específicamente al factor de necrosis tumoral humano (hTNF) en combinacion con otro f4rmaco que es de utilidad para el tratamiento de dicho trastorno. El anticuerpo de la solicitud puede ser un anticuerpo de longitud completa o una porcion de union a antígenos del mismo. La solicitud también abarca conjuntos de elementos que contienen una composicion farmacéutica e instrucciones para la dosificacion. Reivindicacion 2: Una composicion farmacéutica, caracterizada porque comprende 40 mg de D2E7, uno o varios fármacos adicionales y un vehículo aceptable para uso farmacéutico. Reivindicacion 3: La composicion farmacéutica de la cláusula 2, caracterizada porque el otro fármaco es un fármaco anti-reumático modificador de la enfermedad (DMARD), un fármaco anti-inflamatorio no esteroide (NSAID), un esteroide o cualquier combinacion de los mismos. Reivindicacion 4: La composicion farmacéutica de la cláusula 2, caracterizada porque el DMARD es hidroxicloroquina, Leflunomida, metotrexato, oro parenteral, oro oral, sulfasalazina o cualquier combinacion de los mismos. Reivindicacion 5: La composicion farmacéutica de la cláusula 2, caracterizada porque el NSAID es prednisona, ácido folico, celecoxib, rofecoxib, paracetamol, naproxeno, ibuprofeno, metilprednisolona, tramadol, Di-gesic, diclofenac, vicodin, triamcinolona, lidocaína o cualquier combinacion de los mismos.
ARP100102558A 2002-04-26 2010-07-14 Uso de anticuerpos anti-tnf alfa y otro farmaco.metodo de tratamiento. composicion farmaceutica. conjunto de elementos AR077473A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/133,715 US20030206898A1 (en) 2002-04-26 2002-04-26 Use of anti-TNFalpha antibodies and another drug

Publications (1)

Publication Number Publication Date
AR077473A2 true AR077473A2 (es) 2011-08-31

Family

ID=29268783

Family Applications (2)

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ARP030101417A AR039656A1 (es) 2002-04-26 2003-04-24 Uso de anticuerpos anti-tnf alfa y otro farmaco
ARP100102558A AR077473A2 (es) 2002-04-26 2010-07-14 Uso de anticuerpos anti-tnf alfa y otro farmaco.metodo de tratamiento. composicion farmaceutica. conjunto de elementos

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