BR0306444A - Uso de anticorpos anti-tnf(alfa) e outra droga - Google Patents

Uso de anticorpos anti-tnf(alfa) e outra droga

Info

Publication number
BR0306444A
BR0306444A BR0306444-1A BR0306444A BR0306444A BR 0306444 A BR0306444 A BR 0306444A BR 0306444 A BR0306444 A BR 0306444A BR 0306444 A BR0306444 A BR 0306444A
Authority
BR
Brazil
Prior art keywords
antibodies
tnf
another drug
alpha
human antibodies
Prior art date
Application number
BR0306444-1A
Other languages
English (en)
Inventor
Steven Fischkoff
Elliot Chartash
Original Assignee
Abbott Biotech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29268783&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0306444(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Biotech Ltd filed Critical Abbott Biotech Ltd
Publication of BR0306444A publication Critical patent/BR0306444A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C—CHEMISTRY; METALLURGY
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Abstract

"USO DE ANTICORPOS ANTI-TNF<244> E OUTRA DROGA". A presente invenção é dirigida a um método de tratar distúrbios no qual a atividade de TNF<244> seja prejudicial através de administração subcutânea quinzenal de anticorpos humanos, de preferência anticorpos humanos recombinantes, que se ligam especificamente a fator de necrose de tumor a (hTNF<244>) em combinação com outra droga que é útil para o tratamento do distúrbio. Um anticorpo da invenção pode ser um anticorpo de comprimento integral ou uma porção de ligação de antígeno do mesmo. Os kits contendo uma composição farmacêutica e instruções para dosagem também são abrangidos pela invenção.
BR0306444-1A 2002-04-26 2003-04-24 Uso de anticorpos anti-tnf(alfa) e outra droga BR0306444A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/133,715 US20030206898A1 (en) 2002-04-26 2002-04-26 Use of anti-TNFalpha antibodies and another drug
PCT/US2003/012976 WO2004004633A2 (en) 2002-04-26 2003-04-24 Use of tnfalpha antibodies and another drug

Publications (1)

Publication Number Publication Date
BR0306444A true BR0306444A (pt) 2004-10-26

Family

ID=29268783

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0306444-1A BR0306444A (pt) 2002-04-26 2003-04-24 Uso de anticorpos anti-tnf(alfa) e outra droga

Country Status (18)

Country Link
US (1) US20030206898A1 (pt)
EP (3) EP1501545A4 (pt)
JP (2) JP2005523946A (pt)
KR (1) KR20100106631A (pt)
CN (3) CN1649624A (pt)
AR (2) AR039656A1 (pt)
AU (2) AU2003278692B2 (pt)
BR (1) BR0306444A (pt)
CA (1) CA2385777A1 (pt)
IL (2) IL164759A0 (pt)
MX (1) MXPA04010498A (pt)
NZ (1) NZ560793A (pt)
PE (1) PE20040474A1 (pt)
PL (1) PL373333A1 (pt)
TW (2) TW201138826A (pt)
UY (1) UY27780A1 (pt)
WO (1) WO2004004633A2 (pt)
ZA (1) ZA200408509B (pt)

Families Citing this family (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6090382A (en) * 1996-02-09 2000-07-18 Basf Aktiengesellschaft Human antibodies that bind human TNFα
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