UY27780A1 - Uso de anticuerpos anti-tnf alfa y otro fármaco - Google Patents
Uso de anticuerpos anti-tnf alfa y otro fármacoInfo
- Publication number
- UY27780A1 UY27780A1 UY27780A UY27780A UY27780A1 UY 27780 A1 UY27780 A1 UY 27780A1 UY 27780 A UY27780 A UY 27780A UY 27780 A UY27780 A UY 27780A UY 27780 A1 UY27780 A1 UY 27780A1
- Authority
- UY
- Uruguay
- Prior art keywords
- treatment
- tnf alpha
- drug antibodies
- human
- antibodies
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A—HUMAN NECESSITIES
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
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- A—HUMAN NECESSITIES
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
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- A61K31/47—Quinolines; Isoquinolines
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Inorganic Chemistry (AREA)
- Physical Education & Sports Medicine (AREA)
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- Pain & Pain Management (AREA)
- Tropical Medicine & Parasitology (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Mycology (AREA)
- Urology & Nephrology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
Abstract
Método de tratamiento de trastornos en los cuales la actividad del TFNa es nociva, por medio de una administración bisemanal, subcutánea de anticuerpos humanos, preferentemente anticuerpos recombinantes humanos, que se unen especificamente al factor de necrosis tumoral a humano (hTNFa) en combinación con otro fármaco que es de utilidad para el tratamiento de dicho trastorno. El anticuerpo de la invención puede ser un anticuerpo de longitud completa o una porción de unión a antígenos del mismo. La invención también abarca conjuntos de elementos que contienen una composición farmacéutica e instrucciones para la dosificación.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/133,715 US20030206898A1 (en) | 2002-04-26 | 2002-04-26 | Use of anti-TNFalpha antibodies and another drug |
Publications (1)
Publication Number | Publication Date |
---|---|
UY27780A1 true UY27780A1 (es) | 2003-11-28 |
Family
ID=29268783
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY27780A UY27780A1 (es) | 2002-04-26 | 2003-04-25 | Uso de anticuerpos anti-tnf alfa y otro fármaco |
Country Status (18)
Country | Link |
---|---|
US (1) | US20030206898A1 (es) |
EP (3) | EP2196218A3 (es) |
JP (2) | JP2005523946A (es) |
KR (1) | KR20100106631A (es) |
CN (3) | CN1649624A (es) |
AR (2) | AR039656A1 (es) |
AU (2) | AU2003278692B2 (es) |
BR (1) | BR0306444A (es) |
CA (1) | CA2385777A1 (es) |
IL (2) | IL164759A0 (es) |
MX (1) | MXPA04010498A (es) |
NZ (1) | NZ560793A (es) |
PE (1) | PE20040474A1 (es) |
PL (1) | PL373333A1 (es) |
TW (2) | TWI353851B (es) |
UY (1) | UY27780A1 (es) |
WO (1) | WO2004004633A2 (es) |
ZA (1) | ZA200408509B (es) |
Families Citing this family (93)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6090382A (en) | 1996-02-09 | 2000-07-18 | Basf Aktiengesellschaft | Human antibodies that bind human TNFα |
NZ512006A (en) * | 1996-02-09 | 2005-05-27 | Abbott Biotech Ltd | Medical treatment with human TNF-alpha antibodies |
US20040009172A1 (en) * | 2002-04-26 | 2004-01-15 | Steven Fischkoff | Use of anti-TNFalpha antibodies and another drug |
US20090280065A1 (en) * | 2006-04-10 | 2009-11-12 | Willian Mary K | Uses and Compositions for Treatment of Psoriasis |
EP2371859A3 (en) * | 2002-07-19 | 2011-12-28 | Abbott Biotechnology Ltd | Treatment of TNF alpha related disorders |
US20040033228A1 (en) * | 2002-08-16 | 2004-02-19 | Hans-Juergen Krause | Formulation of human antibodies for treating TNF-alpha associated disorders |
MY150740A (en) * | 2002-10-24 | 2014-02-28 | Abbvie Biotechnology Ltd | Low dose methods for treating disorders in which tnf? activity is detrimental |
TWI556829B (zh) * | 2004-04-09 | 2016-11-11 | 艾伯維生物技術有限責任公司 | 用於治療TNFα相關失調症之多重可變劑量療法 |
GB0414054D0 (en) | 2004-06-23 | 2004-07-28 | Owen Mumford Ltd | Improvements relating to automatic injection devices |
AU2005276231A1 (en) * | 2004-08-27 | 2006-03-02 | Cyclacel Limited | Purine and pyrimidine CDK inhibitors and their use for the treatment of autoimmune diseases |
US20060083741A1 (en) * | 2004-10-08 | 2006-04-20 | Hoffman Rebecca S | Treatment of respiratory syncytial virus (RSV) infection |
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CN1649624A (zh) | 2005-08-03 |
JP2010248199A (ja) | 2010-11-04 |
CA2385777A1 (en) | 2003-10-14 |
WO2004004633A2 (en) | 2004-01-15 |
NZ560793A (en) | 2009-11-27 |
PE20040474A1 (es) | 2004-08-12 |
EP2196218A3 (en) | 2010-07-07 |
TWI353851B (en) | 2011-12-11 |
TW200401647A (en) | 2004-02-01 |
CN101890163A (zh) | 2010-11-24 |
PL373333A1 (en) | 2005-08-22 |
KR20100106631A (ko) | 2010-10-01 |
IL209010A0 (en) | 2011-01-31 |
BR0306444A (pt) | 2004-10-26 |
ZA200408509B (en) | 2006-06-28 |
AU2003278692A1 (en) | 2004-01-23 |
EP2196218A2 (en) | 2010-06-16 |
EP1501545A4 (en) | 2006-08-09 |
AU2009200817A1 (en) | 2009-03-26 |
EP1501545A2 (en) | 2005-02-02 |
TW201138826A (en) | 2011-11-16 |
AR077473A2 (es) | 2011-08-31 |
US20030206898A1 (en) | 2003-11-06 |
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