ATE172880T1 - Verwendung von monoklonalen anti-tnf-antikörpern für die behandlung von bakteriellen meningitiden - Google Patents
Verwendung von monoklonalen anti-tnf-antikörpern für die behandlung von bakteriellen meningitidenInfo
- Publication number
- ATE172880T1 ATE172880T1 AT93113072T AT93113072T ATE172880T1 AT E172880 T1 ATE172880 T1 AT E172880T1 AT 93113072 T AT93113072 T AT 93113072T AT 93113072 T AT93113072 T AT 93113072T AT E172880 T1 ATE172880 T1 AT E172880T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- bacterial meningitis
- monoclonal anti
- tnf antibodies
- bacterial
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US93793992A | 1992-08-28 | 1992-08-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE172880T1 true ATE172880T1 (de) | 1998-11-15 |
Family
ID=25470604
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT93113072T ATE172880T1 (de) | 1992-08-28 | 1993-08-16 | Verwendung von monoklonalen anti-tnf-antikörpern für die behandlung von bakteriellen meningitiden |
Country Status (6)
Country | Link |
---|---|
US (1) | US5616321A (de) |
EP (1) | EP0585705B1 (de) |
AT (1) | ATE172880T1 (de) |
DE (1) | DE69321909T2 (de) |
DK (1) | DK0585705T3 (de) |
ES (1) | ES2121907T3 (de) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6277969B1 (en) | 1991-03-18 | 2001-08-21 | New York University | Anti-TNF antibodies and peptides of human tumor necrosis factor |
US7192584B2 (en) | 1991-03-18 | 2007-03-20 | Centocor, Inc. | Methods of treating psoriasis with anti-TNF antibodies |
US6284471B1 (en) | 1991-03-18 | 2001-09-04 | New York University Medical Center | Anti-TNFa antibodies and assays employing anti-TNFa antibodies |
PT614984E (pt) † | 1993-03-05 | 2001-12-28 | Bayer Ag | Anticorpos humanos anti-tnf |
US6090382A (en) | 1996-02-09 | 2000-07-18 | Basf Aktiengesellschaft | Human antibodies that bind human TNFα |
CA2385745C (en) | 2001-06-08 | 2015-02-17 | Abbott Laboratories (Bermuda) Ltd. | Methods of administering anti-tnf.alpha. antibodies |
TWI334439B (en) | 2001-08-01 | 2010-12-11 | Centocor Inc | Anti-tnf antibodies, compositions, methods and uses |
US20030206898A1 (en) | 2002-04-26 | 2003-11-06 | Steven Fischkoff | Use of anti-TNFalpha antibodies and another drug |
US20040033228A1 (en) | 2002-08-16 | 2004-02-19 | Hans-Juergen Krause | Formulation of human antibodies for treating TNF-alpha associated disorders |
MY150740A (en) | 2002-10-24 | 2014-02-28 | Abbvie Biotechnology Ltd | Low dose methods for treating disorders in which tnf? activity is detrimental |
EP2316852B1 (de) | 2002-11-08 | 2014-03-05 | Ablynx N.V. | Stabilisierte Einzel-Domäne-Antikörper |
CN100434440C (zh) * | 2002-12-02 | 2008-11-19 | 阿布格尼克斯公司 | 针对肿瘤坏死因子的抗体及其用途 |
US7101978B2 (en) * | 2003-01-08 | 2006-09-05 | Applied Molecular Evolution | TNF-α binding molecules |
JP4484664B2 (ja) * | 2003-11-27 | 2010-06-16 | キヤノン株式会社 | 記録ヘッドカートリッジ |
US7435799B2 (en) * | 2004-01-08 | 2008-10-14 | Applied Molecular Evolution | TNF-α binding molecules |
TWI439284B (zh) | 2004-04-09 | 2014-06-01 | Abbvie Biotechnology Ltd | 用於治療TNFα相關失調症之多重可變劑量療法 |
KR101465456B1 (ko) | 2005-05-16 | 2014-11-27 | 애브비 바이오테크놀로지 리미티드 | 미란성 다발관절염의 치료를 위한 tnf 억제제의 용도 |
PL1888640T3 (pl) | 2005-05-18 | 2012-08-31 | Ablynx Nv | Ulepszone nanociała skierowane przeciwko czynnikowi martwicy nowotworów typu alfa |
EP3088410A3 (de) | 2006-04-05 | 2016-12-28 | AbbVie Biotechnology Ltd | Antikörperreinigung |
US9605064B2 (en) | 2006-04-10 | 2017-03-28 | Abbvie Biotechnology Ltd | Methods and compositions for treatment of skin disorders |
WO2012149197A2 (en) | 2011-04-27 | 2012-11-01 | Abbott Laboratories | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
JP6175431B2 (ja) | 2011-06-20 | 2017-08-02 | アイカーン スクール オブ メディシン アット マウント サイナイ | ムコ多糖症およびその他のリソソーム障害に対する抗tnf療法 |
US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
WO2013158279A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Protein purification methods to reduce acidic species |
US9181572B2 (en) | 2012-04-20 | 2015-11-10 | Abbvie, Inc. | Methods to modulate lysine variant distribution |
US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
CN104955480A (zh) | 2013-01-25 | 2015-09-30 | 西蒙有限公司 | 用于选择性减少循环的生物活性可溶性tnf的组合物以及用于治疗tnf介导的疾病的方法 |
CA2905010A1 (en) | 2013-03-12 | 2014-09-18 | Abbvie Inc. | Human antibodies that bind human tnf-alpha and methods of preparing the same |
US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
WO2014151878A2 (en) | 2013-03-14 | 2014-09-25 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides |
EP2803365A1 (de) | 2013-05-14 | 2014-11-19 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | Verwendung von Clonazepam in Verbindung mit Antibiotika bei der Behandlung von bakteriell verursachter Meningitis |
WO2015051293A2 (en) | 2013-10-04 | 2015-04-09 | Abbvie, Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
WO2015073884A2 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
WO2016160976A2 (en) | 2015-03-30 | 2016-10-06 | Abbvie Inc. | Monovalent tnf binding proteins |
EP3078675A1 (de) | 2015-04-10 | 2016-10-12 | Ares Trading S.A. | Induktionsdosierschema zur behandlung von krankheiten die von tnf alpha verursacht sind |
US10465003B2 (en) | 2016-02-05 | 2019-11-05 | Janssen Biotech, Inc. | Anti-TNF antibodies, compositions, methods and use for the treatment or prevention of type 1 diabetes |
JOP20190162A1 (ar) | 2016-12-30 | 2019-06-27 | Biocad Joint Stock Co | تركيبة صيدلانية مائية من جسم مضاد لـ tnf? أحادي النسيلة معاود الارتباط الجيني |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL73883A (en) * | 1984-12-20 | 1990-12-23 | Yeda Res & Dev | Monoclonal antibodies against tnf-alpha,hybridomas producing them and method for the purification of tnf-alpha |
DE3631229A1 (de) * | 1986-09-13 | 1988-03-24 | Basf Ag | Monoklonale antikoerper gegen humanen tumornekrosefaktor (tnf) und deren verwendung |
DE3888224T2 (de) * | 1987-04-24 | 1994-07-21 | Teijin Ltd | Bestimmung vom Tumornekrosefaktor; monoklonaler Antikörper und Zusammensetzung. |
GB8806339D0 (en) * | 1988-03-17 | 1988-04-13 | Hoffmann La Roche | Monoclonal antibodies |
NZ229922A (en) * | 1988-07-18 | 1992-04-28 | Chiron Corp | Monoclonal antibodies specifically binding cachectin (tumor necrosis factor) and compositions |
EP0355067A1 (de) * | 1988-08-19 | 1990-02-21 | Celltech Limited | Arzneimittel gegen bösartige Gewebeneubildung |
US5360716A (en) * | 1988-10-24 | 1994-11-01 | Otsuka Pharmaceutical Co., Ltd. | Human tumor necrosis factor αspecific monoclonal antibody and method for detecting human tumor necrosis factor α |
GB8905400D0 (en) * | 1989-03-09 | 1989-04-19 | Jonker Margreet | Medicaments |
GB8921123D0 (en) * | 1989-09-19 | 1989-11-08 | Millar Ann B | Treatment of ards |
WO1992003145A1 (en) * | 1990-08-27 | 1992-03-05 | Peptide Technology Ltd. | Method of treating viral infection |
GB9028123D0 (en) * | 1990-12-28 | 1991-02-13 | Erba Carlo Spa | Monoclonal antibodies against human tumor necrosis factor alpha |
AU668864B2 (en) * | 1991-03-18 | 1996-05-23 | Centocor Inc. | Chimeric antibodies specific for human tumor necrosis factor |
WO1994008619A1 (en) * | 1992-10-08 | 1994-04-28 | The Kennedy Institute Of Rheumatology | Treatment of autoimmune and inflammatory disorders |
GB9225448D0 (en) * | 1992-12-04 | 1993-01-27 | Erba Carlo Spa | Improved synthesis of polymer bioactive conjugates |
WO1995015179A1 (en) * | 1993-12-01 | 1995-06-08 | Unisearch Limited | Method of treating intestinal disorders |
-
1993
- 1993-08-16 AT AT93113072T patent/ATE172880T1/de active
- 1993-08-16 DK DK93113072T patent/DK0585705T3/da active
- 1993-08-16 DE DE69321909T patent/DE69321909T2/de not_active Expired - Lifetime
- 1993-08-16 EP EP93113072A patent/EP0585705B1/de not_active Expired - Lifetime
- 1993-08-16 ES ES93113072T patent/ES2121907T3/es not_active Expired - Lifetime
-
1995
- 1995-03-23 US US08/410,006 patent/US5616321A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0585705B1 (de) | 1998-11-04 |
EP0585705A1 (de) | 1994-03-09 |
DE69321909D1 (de) | 1998-12-10 |
DE69321909T2 (de) | 1999-04-01 |
US5616321A (en) | 1997-04-01 |
DK0585705T3 (da) | 1999-07-26 |
ES2121907T3 (es) | 1998-12-16 |
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