AR066195A1 - Microorganismo modificado metabolicamente util para la produccion de 1,2- propanodiol - Google Patents

Microorganismo modificado metabolicamente util para la produccion de 1,2- propanodiol

Info

Publication number
AR066195A1
AR066195A1 ARP080101212A ARP080101212A AR066195A1 AR 066195 A1 AR066195 A1 AR 066195A1 AR P080101212 A ARP080101212 A AR P080101212A AR P080101212 A ARP080101212 A AR P080101212A AR 066195 A1 AR066195 A1 AR 066195A1
Authority
AR
Argentina
Prior art keywords
production
propanediol
propanodiol
modified microorganism
used modified
Prior art date
Application number
ARP080101212A
Other languages
English (en)
Original Assignee
Metabolic Explorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolic Explorer Sa filed Critical Metabolic Explorer Sa
Publication of AR066195A1 publication Critical patent/AR066195A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Microorganismo util para la produccion de 1,2-propanodiol a partir de una fuente de carbono, en el que dicho rnicroorganismo se caracteriza por: una mejora de la actividad de la ruta de biosíntesis desde la fosfato de dihidroxiacetona al 1,2-propanodiol; una atenuacion de la actividad de la gliceraldehído-3-fosfato deshidrogenasa. Reivindicacion 28: Un procedimiento para la preparacion de 1,2-propanodiol, en el que un microorganismo segun cualquiera de las reivindicaciones 1 a 27 crece en un medio de crecimiento apropiado que contiene una fuente de carbono y en el que se recupera el 1,2-propanodiol producido.
ARP080101212A 2007-03-23 2008-03-25 Microorganismo modificado metabolicamente util para la produccion de 1,2- propanodiol AR066195A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IB2007001675 2007-03-23

Publications (1)

Publication Number Publication Date
AR066195A1 true AR066195A1 (es) 2009-08-05

Family

ID=38857922

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080101212A AR066195A1 (es) 2007-03-23 2008-03-25 Microorganismo modificado metabolicamente util para la produccion de 1,2- propanodiol

Country Status (12)

Country Link
US (1) US20100261239A1 (es)
EP (1) EP2139985A1 (es)
JP (1) JP2010521190A (es)
KR (1) KR20100015809A (es)
CN (1) CN101679940A (es)
AR (1) AR066195A1 (es)
BR (1) BRPI0809039A2 (es)
CA (1) CA2679987A1 (es)
IL (1) IL200720A0 (es)
MX (1) MX2009010219A (es)
TW (1) TW200909585A (es)
WO (1) WO2008116848A1 (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010051849A1 (en) 2008-11-07 2010-05-14 Metabolic Explorer Use of sucrose as substrate for fermentative production of 1,2-propanediol
KR101176148B1 (ko) 2009-02-16 2012-08-22 한국과학기술원 ＹｑｈＣ 단백질 변이체, 이를 코딩하는 뉴클레오타이드 서열 및 이 뉴클레오타이드 서열을 발현가능한 형태로 포함하는 ＹｑｈＤ 단백질 과발현 숙주세포
EP2233562A1 (en) 2009-03-24 2010-09-29 Metabolic Explorer Method for producing high amount of glycolic acid by fermentation
CN102498215A (zh) 2009-06-04 2012-06-13 基因组股份公司 生产1,4-丁二醇的微生物和相关方法
US8969053B2 (en) 2009-07-30 2015-03-03 Metabolic Explorer Mutant YqhD enzyme for the production of a biochemical by fermentation
US8980604B2 (en) 2009-07-30 2015-03-17 Metabolic Explorer Mutant glycerol dehydrogenase (GlyDH) for the production of a biochemical by fermentation
US8497102B2 (en) 2009-07-30 2013-07-30 Metabolic Explorer Mutant methylglyoxal synthase (MGS) for the production of a biochemical by fermentation
BR112012003883A8 (pt) * 2009-08-21 2018-02-06 Mascoma Corp Microorganismos recombinantes, processo de conversão de biomassa lignocelulósica em 1,2-propanodiol ou isopropanol, via metabólica engenheirada, agrupamento genético, e método de identificação de diol desidratase independente da vitamina b12 que converte propanodiol em propanal
KR20160114184A (ko) 2009-11-18 2016-10-04 미리안트 코포레이션 화합물들의 효과적인 생산을 위한 미생물 엔지니어링
EP2652140A1 (en) 2010-12-17 2013-10-23 Total Research & Technology Feluy Process for producing propylene from syngas via fermentative propanol production and dehydration
SG192958A1 (en) 2011-02-28 2013-09-30 Midori Renewables Inc Polymeric acid catalysts and uses thereof
WO2012135420A2 (en) * 2011-04-01 2012-10-04 Unifersity Of Florida Research Foundation, Inc. Over-expression of hadh-dependent oxidoreductase (fuco) for increasing furfural or 5-hydroxymethylfurfural tolerance
EP2532751A1 (en) 2011-06-10 2012-12-12 Metabolic Explorer Use of inducible promoters in the fermentative production of 1,2-propanediol
CA2839373A1 (en) 2011-06-15 2012-12-20 B.R.A.I.N. Biotechnology Research And Information Network Ag New means and methods for producing propanediol
WO2013163230A2 (en) * 2012-04-24 2013-10-31 Midori Renewables, Inc. Bio-based polymers and methods of producing thereof
CN104718282A (zh) 2012-08-10 2015-06-17 Opx生物工艺学公司 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法
US9238845B2 (en) 2012-08-24 2016-01-19 Midori Usa, Inc. Methods of producing sugars from biomass feedstocks
CN102994577B (zh) * 2012-10-26 2015-01-21 上海交通大学 微生物细胞转化法生产丙酮醇的方法
WO2014146026A1 (en) * 2013-03-15 2014-09-18 Opx Biotechnologies, Inc. Bioproduction of chemicals
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
CN106795483A (zh) 2013-07-19 2017-05-31 嘉吉公司 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
EP3347478B1 (en) 2015-09-10 2022-09-21 Metabolic Explorer New lactaldehyde reductases for the production of 1,2-propanediol
WO2017139420A1 (en) * 2016-02-09 2017-08-17 Kembiotix Llc Biological fermentation using dihydroxyacetone as a source of carbon
MX2019000075A (es) * 2016-07-08 2019-05-02 Metabolic Explorer Sa Metodo para la produccion fermentativa de moleculas de interes por microorganismos que comprenden genes que codifican el sistema de fosfotransferasa de azucar (pts).
EP3342873A1 (en) 2016-12-29 2018-07-04 Metabolic Explorer Conversion of methylglyoxal into hydroxyacetone using enzymes and applications thereof
EP3354742A1 (en) * 2017-01-26 2018-08-01 Metabolic Explorer Methods and microorganisms for the production of glycolic acid and/or glyoxylic acid
WO2018144701A2 (en) 2017-02-02 2018-08-09 Cargill Incorporated Genetically modified cells that produce c6-c10 fatty acid derivatives
KR102173766B1 (ko) * 2018-11-05 2020-11-04 서강대학교산학협력단 메틸영양세균을 이용한 1,2-프로필렌글라이콜 생산용 조성물 및 그의 생산 방법
CN115261292B (zh) * 2021-04-29 2023-06-09 中国科学院上海高等研究院 改造的克雷伯氏菌属细菌及其生产1,2-丙二醇的应用和方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6087140A (en) * 1997-02-19 2000-07-11 Wisconsin Alumni Research Foundation Microbial production of 1,2-propanediol from sugar
AU2003256480B2 (en) * 2002-07-10 2008-03-06 The Penn State Research Foundation Method for determining gene knockout strategies
ATE493490T1 (de) * 2002-10-04 2011-01-15 Du Pont Verfahren zur biologischen herstellung von 1,3- propandiol mit hoher ausbeute
FR2864967B1 (fr) * 2004-01-12 2006-05-19 Metabolic Explorer Sa Microorganisme evolue pour la production de 1,2-propanediol

Also Published As

Publication number Publication date
CA2679987A1 (en) 2008-10-02
JP2010521190A (ja) 2010-06-24
IL200720A0 (en) 2011-08-01
EP2139985A1 (en) 2010-01-06
MX2009010219A (es) 2009-10-19
TW200909585A (en) 2009-03-01
WO2008116848A1 (en) 2008-10-02
US20100261239A1 (en) 2010-10-14
BRPI0809039A2 (pt) 2014-09-16
KR20100015809A (ko) 2010-02-12
CN101679940A (zh) 2010-03-24

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