BR112012003883A8 - Microorganismos recombinantes, processo de conversão de biomassa lignocelulósica em 1,2-propanodiol ou isopropanol, via metabólica engenheirada, agrupamento genético, e método de identificação de diol desidratase independente da vitamina b12 que converte propanodiol em propanal - Google Patents

Microorganismos recombinantes, processo de conversão de biomassa lignocelulósica em 1,2-propanodiol ou isopropanol, via metabólica engenheirada, agrupamento genético, e método de identificação de diol desidratase independente da vitamina b12 que converte propanodiol em propanal

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Publication number
BR112012003883A8
BR112012003883A8 BR112012003883A BR112012003883A BR112012003883A8 BR 112012003883 A8 BR112012003883 A8 BR 112012003883A8 BR 112012003883 A BR112012003883 A BR 112012003883A BR 112012003883 A BR112012003883 A BR 112012003883A BR 112012003883 A8 BR112012003883 A8 BR 112012003883A8
Authority
BR
Brazil
Prior art keywords
propanediol
isopropanol
conversion
lignocellulosic biomass
propanal
Prior art date
Application number
BR112012003883A
Other languages
English (en)
Other versions
BR112012003883A2 (pt
Inventor
Mcbride John
Rajgarhia Vineet
J Shaw Arthur Iv
A Tripathi Shital
Brevnova Elena
Caiazza Nichy
Van Dijken Hans
Froehlich Allan
Ryan Sillers William
Flatt Jim
Original Assignee
Mascoma Corp
Lallemand Hungary Liquidity Man Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mascoma Corp, Lallemand Hungary Liquidity Man Llc filed Critical Mascoma Corp
Publication of BR112012003883A2 publication Critical patent/BR112012003883A2/pt
Publication of BR112012003883A8 publication Critical patent/BR112012003883A8/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C12P7/28—Acetone-containing products
    • C12P7/36—Acetone-containing products produced from substrate containing grain or cereal material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P2203/00—Fermentation products obtained from optionally pretreated or hydrolyzed cellulosic or lignocellulosic material as the carbon source
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

MICRO-ORGANISMOS RECOMBINANTES, PROCESSO DE CONVERSÃO DE BIOMASSA LIGNOCELULÓSICA EM 1 ,2- PROPANODIOL OU ISOPROPANOL, VIA METABÓLICA ENGENHEIRADA, AGRUPAMENTO GENÉTICO, E MÉTODO DE IDENTIFICAÇÃO DE DIOL DESIDRATASE INDEPENDENTE DA VITAMINA B12 QUE CONVERTE PROPANODIOL EM PROPANAL. A presente invenção fornece novas vias metabólicas que levam à formação de propanol, álcool ou poliol em um sistema de bioprocessamento consolidado (CBP), onde a biomassa lignocelulósica é eficientemente convertida em tais produtos. Mais especificamente, a invenção fornece um micro-organismo recombinante, onde o micro-organismo expressa uma ou mais enzimas nativas e/ou heterólogas; onde a uma ou mais enzimas funcionam com uma ou mais vias metabólicas engenheiradas para alcançar: (1) conversão de uma fonte de carboidrato em 1,2-propanodiol, isopropropanol, etanol e/ou glicerol; (2) conversão de uma fonte de carboidrato em n-propanol e isopropanol; (3) conversão de uma fonte de carboidrato em isopropanol e metanol; ou (4) conversão de uma fonte de carboidrato em propanodiol e acetona; em que a uma ou mais enzimas nativas e/ou heterólogas são ativadas, suprarreguladas ou infrarreguladas.
BR112012003883A 2009-08-21 2010-08-20 Microorganismos recombinantes, processo de conversão de biomassa lignocelulósica em 1,2-propanodiol ou isopropanol, via metabólica engenheirada, agrupamento genético, e método de identificação de diol desidratase independente da vitamina b12 que converte propanodiol em propanal BR112012003883A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23595909P 2009-08-21 2009-08-21
US29879010P 2010-01-27 2010-01-27
PCT/US2010/046172 WO2011022651A1 (en) 2009-08-21 2010-08-20 Production of propanols, alcohols, and polyols in consolidated bioprocessing organisms

Publications (2)

Publication Number Publication Date
BR112012003883A2 BR112012003883A2 (pt) 2015-09-01
BR112012003883A8 true BR112012003883A8 (pt) 2018-02-06

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012003883A BR112012003883A8 (pt) 2009-08-21 2010-08-20 Microorganismos recombinantes, processo de conversão de biomassa lignocelulósica em 1,2-propanodiol ou isopropanol, via metabólica engenheirada, agrupamento genético, e método de identificação de diol desidratase independente da vitamina b12 que converte propanodiol em propanal

Country Status (8)

Country Link
US (3) US9957530B2 (pt)
EP (1) EP2467490A1 (pt)
CN (1) CN102666862A (pt)
AU (2) AU2010284110B2 (pt)
BR (1) BR112012003883A8 (pt)
CA (1) CA2772081A1 (pt)
NZ (3) NZ712586A (pt)
WO (1) WO2011022651A1 (pt)

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Also Published As

Publication number Publication date
AU2010284110B2 (en) 2015-10-29
US20120322078A1 (en) 2012-12-20
NZ598374A (en) 2014-10-31
US11634735B2 (en) 2023-04-25
BR112012003883A2 (pt) 2015-09-01
US9957530B2 (en) 2018-05-01
US20180208951A1 (en) 2018-07-26
CA2772081A1 (en) 2011-02-24
US20200325500A1 (en) 2020-10-15
EP2467490A1 (en) 2012-06-27
NZ624392A (en) 2015-12-24
AU2015238904A1 (en) 2015-11-05
CN102666862A (zh) 2012-09-12
AU2010284110A1 (en) 2012-03-22
WO2011022651A1 (en) 2011-02-24
NZ712586A (en) 2017-06-30

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B09B Patent application refused [chapter 9.2 patent gazette]

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