BR112021018925A2 - Modificação metabólica para consumo simultâneo de xilose e glicose para produção de produtos químicos a partir de açúcares de segunda geração - Google Patents

Modificação metabólica para consumo simultâneo de xilose e glicose para produção de produtos químicos a partir de açúcares de segunda geração

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Publication number
BR112021018925A2
BR112021018925A2 BR112021018925A BR112021018925A BR112021018925A2 BR 112021018925 A2 BR112021018925 A2 BR 112021018925A2 BR 112021018925 A BR112021018925 A BR 112021018925A BR 112021018925 A BR112021018925 A BR 112021018925A BR 112021018925 A2 BR112021018925 A2 BR 112021018925A2
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BR
Brazil
Prior art keywords
glucose
xylose
metabolic modification
simultaneous consumption
produce chemicals
Prior art date
Application number
BR112021018925A
Other languages
English (en)
Inventor
Fernanda Beraldi Zeidler Ane
Pedersen Parizzi Lucas
Maria Rodege Gogola Kolling Veronica
Original Assignee
Braskem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Braskem Sa filed Critical Braskem Sa
Publication of BR112021018925A2 publication Critical patent/BR112021018925A2/pt

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
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    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
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    • C12N9/0004—Oxidoreductases (1.)
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    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
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    • C12P7/00—Preparation of oxygen-containing organic compounds
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12P2203/00—Fermentation products obtained from optionally pretreated or hydrolyzed cellulosic or lignocellulosic material as the carbon source
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    • C12Y—ENZYMES
    • C12Y503/00—Intramolecular oxidoreductases (5.3)
    • C12Y503/01—Intramolecular oxidoreductases (5.3) interconverting aldoses and ketoses (5.3.1)
    • C12Y503/01005—Xylose isomerase (5.3.1.5)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
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  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
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  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
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  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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Abstract

modificação metabólica para consumo simultâneo de xilose e glicose para produção de produtos químicos a partir de açúcares de segunda geração. a presente invenção refere-se a métodos para modificar geneticamente micróbios para produzir um micróbio capaz de consumir, simultaneamente, xilose e glicose para aumentar a produtividade de produtos químicos desejados. a divulgação fornece, adicionalmente, bactérias modificadas que são capazes de consumir, simultaneamente, xilose e glicose, e composições que compreendem os micróbios.
BR112021018925A 2019-04-04 2020-04-06 Modificação metabólica para consumo simultâneo de xilose e glicose para produção de produtos químicos a partir de açúcares de segunda geração BR112021018925A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962829398P 2019-04-04 2019-04-04
PCT/BR2020/050115 WO2020198830A1 (en) 2019-04-04 2020-04-06 Metabolic engineering for simultaneous consumption of xylose and glucose for production of chemicals from second generation sugars

Publications (1)

Publication Number Publication Date
BR112021018925A2 true BR112021018925A2 (pt) 2022-01-18

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BR112021018925A BR112021018925A2 (pt) 2019-04-04 2020-04-06 Modificação metabólica para consumo simultâneo de xilose e glicose para produção de produtos químicos a partir de açúcares de segunda geração

Country Status (6)

Country Link
US (1) US11746361B2 (pt)
EP (1) EP3935154A1 (pt)
JP (1) JP2022528894A (pt)
CN (1) CN114008197A (pt)
BR (1) BR112021018925A2 (pt)
WO (1) WO2020198830A1 (pt)

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JPWO2023032950A1 (pt) * 2021-08-30 2023-03-09
DE102022119514A1 (de) * 2022-08-03 2024-02-08 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein Genetisch veränderte Zellen von Methylorubrum zur fermentativen Produktion von Glycolsäure und Milchsäure aus Cx-Verbindungen
CN116240232A (zh) * 2022-12-20 2023-06-09 天津科技大学 木葡糖酸醋杆菌中Weimberg木糖代谢途径的构建方法

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US20050214913A1 (en) 2004-03-16 2005-09-29 Marchenko Aleksey N Method for producing L-amino acids by fermentation using bacteria having enhanced expression of xylose utilization genes
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Also Published As

Publication number Publication date
WO2020198830A1 (en) 2020-10-08
EP3935154A1 (en) 2022-01-12
JP2022528894A (ja) 2022-06-16
CN114008197A (zh) 2022-02-01
US11746361B2 (en) 2023-09-05
US20200318146A1 (en) 2020-10-08

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