AR027544A1 - Diagnostico basado en compuestos de tetrazolio - Google Patents
Diagnostico basado en compuestos de tetrazolioInfo
- Publication number
- AR027544A1 AR027544A1 ARP010100834A ARP010100834A AR027544A1 AR 027544 A1 AR027544 A1 AR 027544A1 AR P010100834 A ARP010100834 A AR P010100834A AR P010100834 A ARP010100834 A AR P010100834A AR 027544 A1 AR027544 A1 AR 027544A1
- Authority
- AR
- Argentina
- Prior art keywords
- reagent
- flavin
- analyte
- formation
- whole blood
- Prior art date
Links
- CWRVKFFCRWGWCS-UHFFFAOYSA-N Pentrazole Chemical class C1CCCCC2=NN=NN21 CWRVKFFCRWGWCS-UHFFFAOYSA-N 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 4
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 abstract 3
- 239000012491 analyte Substances 0.000 abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 102000001554 Hemoglobins Human genes 0.000 abstract 2
- 108010054147 Hemoglobins Proteins 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- 239000008280 blood Substances 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 abstract 2
- 150000002826 nitrites Chemical class 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 239000013060 biological fluid Substances 0.000 abstract 1
- 238000004061 bleaching Methods 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 239000012992 electron transfer agent Substances 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 125000003831 tetrazolyl group Chemical group 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/525—Multi-layer analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/64—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving ketones
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/97—Test strip or test slide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/17—Nitrogen containing
- Y10T436/173076—Nitrite or nitrate
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Emergency Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
Se describe un reactivo que es adecuado para medir la concentracion de un analito en un fluido biologico que contiene hemoglobina, tal como sangre entera;el reactivo comprende una enzima dependiente de flavina que tiene especificidad por el analito, un cofactor de flavina si, y solamente si, una flavina no estáunida a la enzima, un precursor de colorante de tetrazolio, un agente de transferencia de electrones y una sal de nitrito; el reactivo provoca formacion decolorante que es una medida de la concentracion de analito; la sal de nitrito suprime la formacion de colorante de interferencia provocada de manera noenzimática por la hemoglobina; de manera preferible, el reactivo se utiliza en una tira seca para medir glucosa en sangre entera.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/513,071 US6656697B1 (en) | 1998-09-28 | 2000-02-25 | Diagnostics based on tetrazolium compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
AR027544A1 true AR027544A1 (es) | 2003-04-02 |
Family
ID=24041784
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP010100834A AR027544A1 (es) | 2000-02-25 | 2001-02-23 | Diagnostico basado en compuestos de tetrazolio |
Country Status (22)
Country | Link |
---|---|
US (3) | US6656697B1 (es) |
EP (1) | EP1130111B1 (es) |
JP (1) | JP2001292795A (es) |
KR (1) | KR20010085564A (es) |
CN (1) | CN1214117C (es) |
AR (1) | AR027544A1 (es) |
AT (1) | ATE278804T1 (es) |
AU (1) | AU782774B2 (es) |
BR (1) | BR0102467A (es) |
CA (1) | CA2337562A1 (es) |
DE (1) | DE60106110T2 (es) |
DK (1) | DK1130111T3 (es) |
ES (1) | ES2230240T3 (es) |
HK (1) | HK1038772A1 (es) |
IL (1) | IL141580A0 (es) |
MX (1) | MXPA01002062A (es) |
MY (1) | MY134005A (es) |
NO (1) | NO20010939L (es) |
PT (1) | PT1130111E (es) |
RU (1) | RU2269784C2 (es) |
SG (1) | SG100621A1 (es) |
ZA (1) | ZA200101543B (es) |
Families Citing this family (150)
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2001
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- 2001-02-23 AT AT01301670T patent/ATE278804T1/de active
- 2001-02-23 EP EP01301670A patent/EP1130111B1/en not_active Expired - Lifetime
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- 2001-02-23 ZA ZA200101543A patent/ZA200101543B/xx unknown
- 2001-02-23 RU RU2001105186/15A patent/RU2269784C2/ru not_active IP Right Cessation
- 2001-02-23 DE DE60106110T patent/DE60106110T2/de not_active Expired - Lifetime
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- 2001-02-23 BR BR0102467-1A patent/BR0102467A/pt not_active IP Right Cessation
- 2001-02-23 MY MYPI20010824A patent/MY134005A/en unknown
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EP1130111A2 (en) | 2001-09-05 |
ATE278804T1 (de) | 2004-10-15 |
RU2269784C2 (ru) | 2006-02-10 |
AU2321001A (en) | 2001-08-30 |
ES2230240T3 (es) | 2005-05-01 |
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NO20010939D0 (no) | 2001-02-23 |
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AU782774B2 (en) | 2005-08-25 |
US20050112712A1 (en) | 2005-05-26 |
EP1130111B1 (en) | 2004-10-06 |
PT1130111E (pt) | 2005-01-31 |
JP2001292795A (ja) | 2001-10-23 |
CN1214117C (zh) | 2005-08-10 |
BR0102467A (pt) | 2001-12-04 |
DE60106110D1 (de) | 2004-11-11 |
EP1130111A3 (en) | 2002-07-03 |
CA2337562A1 (en) | 2001-08-25 |
MXPA01002062A (es) | 2002-08-20 |
DE60106110T2 (de) | 2006-03-09 |
CN1317575A (zh) | 2001-10-17 |
IL141580A0 (en) | 2002-03-10 |
DK1130111T3 (da) | 2005-02-28 |
ZA200101543B (en) | 2002-08-23 |
US6656697B1 (en) | 2003-12-02 |
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