AR012125A1 - UNA SAL DE UN COMPUESTO DERIVADO DEL ÁCIDO NAFTIRIDINA CARBOXíLICO , SU USO PARA LA FABRICACIoN DE UN MEDICAMENTO , PROCEDIMIENTO PARA PREPARARLA Y UNA COMPOSICIoN FARMACÉUTICA QUE LO COMPRENDE - Google Patents
UNA SAL DE UN COMPUESTO DERIVADO DEL ÁCIDO NAFTIRIDINA CARBOXíLICO , SU USO PARA LA FABRICACIoN DE UN MEDICAMENTO , PROCEDIMIENTO PARA PREPARARLA Y UNA COMPOSICIoN FARMACÉUTICA QUE LO COMPRENDEInfo
- Publication number
- AR012125A1 AR012125A1 ARP980101268A ARP980101268A AR012125A1 AR 012125 A1 AR012125 A1 AR 012125A1 AR P980101268 A ARP980101268 A AR P980101268A AR P980101268 A ARP980101268 A AR P980101268A AR 012125 A1 AR012125 A1 AR 012125A1
- Authority
- AR
- Argentina
- Prior art keywords
- naftiridine
- carboxyllic
- prepare
- salt
- procedure
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/04—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing only one sulfo group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR19970009840 | 1997-03-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR012125A1 true AR012125A1 (es) | 2000-09-27 |
Family
ID=19500439
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP980101268A AR012125A1 (es) | 1997-03-21 | 1998-03-20 | UNA SAL DE UN COMPUESTO DERIVADO DEL ÁCIDO NAFTIRIDINA CARBOXíLICO , SU USO PARA LA FABRICACIoN DE UN MEDICAMENTO , PROCEDIMIENTO PARA PREPARARLA Y UNA COMPOSICIoN FARMACÉUTICA QUE LO COMPRENDE |
Country Status (38)
Families Citing this family (26)
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GB9820405D0 (en) | 1998-09-18 | 1998-11-11 | Smithkline Beecham Plc | Process |
IL145238A0 (en) * | 1999-03-19 | 2002-06-30 | Knoll Gmbh | Treatment of osteoarthritis |
US6331550B1 (en) | 1999-06-29 | 2001-12-18 | Smithkline Beecham Corporation | Methods of use of quinolone compounds against anaerobic pathogenic bacteria |
US6262071B1 (en) | 1999-06-29 | 2001-07-17 | Smithkline Beecham Corporation | Methods of use of antimicrobial compounds against pathogenic amycoplasma bacteria |
CA2282066C (en) | 1999-06-29 | 2010-09-07 | Smithkline Beecham Corporation | Methods of use of quinolone compounds against atypical upper respiratory pathogenic bacteria |
US6803376B1 (en) | 1999-06-29 | 2004-10-12 | Smithkline Beecham Corporation | Method of use of quinolone compounds against pneumococcal and haemophilus bacteria |
GB9920917D0 (en) | 1999-09-03 | 1999-11-10 | Sb Pharmco Inc | Novel process |
GB9920919D0 (en) | 1999-09-03 | 1999-11-10 | Sb Pharmco Inc | Novel compound |
JP2001097864A (ja) * | 1999-09-24 | 2001-04-10 | Smithkline Beecham Corp | 呼吸管および尿路病原性細菌に対するフルオロキノリン化合物の使用方法 |
WO2001021176A1 (en) * | 1999-09-22 | 2001-03-29 | Smithkline Beecham Corporation | Methods of use of fluoroquinolone compounds against bacteria |
GR1003520B (el) * | 1999-09-22 | 2001-01-22 | Smithkline Beecham Plc | Μεθοδος χρησης ενωσεων φλουοροκινολονης εναντια σε νοσοκομειακα αρνητικα κατα gramμ παθογενων βακτηριδιων |
JP2001097863A (ja) * | 1999-09-24 | 2001-04-10 | Smithkline Beecham Corp | 嫌気性病原菌に対するフルオロキノロン化合物の使用法 |
JP2001097891A (ja) * | 1999-09-24 | 2001-04-10 | Smithkline Beecham Corp | 呼吸器系病原菌に対するフルオロキノロン化合物の使用法 |
GR1003521B (el) * | 1999-09-23 | 2001-01-22 | Smithkline Beecham Plc | Μεθοδοι χρησεως ενωσεων φλουοροκινολονης εναντια κατα gram θετικων παθογονων βακτηριδιων |
KR20010091379A (ko) * | 2000-03-15 | 2001-10-23 | 성재갑 | 7-(4-아미노메틸-3-옥심)피롤리딘 치환체를 갖는 퀴놀린카르복실산 유도체의 신규 제조방법 |
ES2314082T3 (es) | 2001-08-02 | 2009-03-16 | Lg Life Sciences Limited | Procedimientos para la produccion de derivados amino protegidos de 4-aminometilenpirrolidin-3-ona, gemifloxacina y sus sales. |
DE60222298T2 (de) * | 2001-11-30 | 2008-01-03 | Lg Life Sciences Ltd. | Verfahren zur behandlung von bakteriellen infektionen mit gemifloxacin oder einem seiner salze und einem beta-lactam-antibiotikum |
KR100517638B1 (ko) | 2002-04-08 | 2005-09-28 | 주식회사 엘지생명과학 | 게미플록사신 산염의 새로운 제조방법 |
AR043880A1 (es) * | 2003-04-22 | 2005-08-17 | Solvay Pharm Gmbh | Mesilato acido de 4-(4.trans-hidroxiciclohexil) amino-2-fenil-7h-pirrolo (2,3-d) pirimidina y sus formas polimorfas |
EP1891037A1 (en) | 2005-06-15 | 2008-02-27 | Hetero Drugs Limited | Gemifloxacin process and polymorphs |
PL1993547T3 (pl) * | 2006-03-07 | 2013-08-30 | Wockhardt Ltd | Proleki kwasu benzochinolizyno-2-karboksylowego |
WO2010001408A2 (en) * | 2008-06-06 | 2010-01-07 | Matrix Laboratories Ltd. | Novel polymorphic forms of gemifloxacin mesylate |
WO2010146594A1 (en) * | 2009-06-16 | 2010-12-23 | Hetero Research Foundation | Novel polymorphs of gemifloxacin mesylate |
EP2491921A1 (en) | 2011-02-25 | 2012-08-29 | Deva Holding Anonim Sirketi | Conservation of anhydrous form of gemifloxacin |
KR102076118B1 (ko) * | 2012-02-27 | 2020-02-11 | 브리스톨-마이어스 스큅 컴퍼니 | N-(5S,6S,9R)-5-아미노-6-(2,3-디플루오로페닐)-6,7,8,9-테트라히드로-5H-시클로헵타[b]피리딘-9-일-4-(2-옥소-2,3-디히드로-1H-이미다조[4,5-b]피리딘-1-일)피페리딘-1-카르복실레이트, 헤미술페이트 염 |
CZ2016104A3 (cs) * | 2016-02-24 | 2017-09-06 | Zentiva, K.S. | Krystalické modifikace solí methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}fenyl)amino](fenyl)methyliden}-2-oxo-2,3-dihydro-1H-indol-6-karboxylátu a způsoby jejich přípravy |
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AR223983A1 (es) | 1978-08-25 | 1981-10-15 | Dainippon Pharmaceutical Co | Un procedimiento para-preparar derivados de acido 6-halogeno-4-oxo-7-(1-piperazinil)-1,8-naftiridin-3-carboxilico |
ES8304117A1 (es) | 1981-06-11 | 1983-02-16 | Warner Lambert Co | "un procedimiento para preparar sales de compuestos de naftiridina y quinoleina". |
IN162769B (OSRAM) | 1984-11-13 | 1988-07-09 | Kyorin Seiyaku Kk | |
NZ222047A (en) | 1986-10-08 | 1991-01-29 | Bristol Myers Co | Quinoline - or naphthyridine - carboxylic acid anti-bacterial agents |
JPH01100165A (ja) | 1987-10-13 | 1989-04-18 | Shionogi & Co Ltd | オキシムまたはヒドロキシアミン誘導体系抗菌剤 |
US4920120A (en) | 1988-01-25 | 1990-04-24 | Warner-Lambert Company | Antibacterial agents |
US4931446A (en) * | 1988-03-23 | 1990-06-05 | Abbott Laboratories | Antimicrobial for in-vitro diagnostic kits |
CA1336090C (en) * | 1988-08-31 | 1995-06-27 | Isao Hayakawa | Spiro-substituted cyclic amines of quinolone derivatives |
US5286723A (en) * | 1988-08-31 | 1994-02-15 | Daiichi Seiyaku Co., Ltd. | Spiro compound |
IE66202B1 (en) | 1989-08-16 | 1995-12-13 | Pfizer | Azabicyclo quinolone carboxylic acids |
US5276041A (en) | 1991-11-08 | 1994-01-04 | Kaken Pharmaceutical Co., Ltd. | Oxime derivatives |
WO1993025545A1 (en) | 1992-06-09 | 1993-12-23 | Korea Research Institute Of Chemical Technology | Novel quinoline derivatives and processes for preparing the same |
US5776944A (en) * | 1994-06-16 | 1998-07-07 | Lg Chemical Ltd. | 7-(4-aminomethyl-3-methyloxyiminopyrroplidin-1-yl)-1-cyclopropyl-6-flu oro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid and the process for the preparation thereof |
DE69509442T2 (de) * | 1994-06-16 | 1999-09-02 | Lg Chemical Ltd. | Chinolincarbonsäurederivate mit 7-(4-Amino-methyl-3-oxim)-pyrrolidin-Substituenten und Verfahren zu ihrer Herstellung |
WO1996012704A1 (fr) | 1994-10-20 | 1996-05-02 | Wakunaga Seiyaku Kabushiki Kaisha | Nouveau derive de pyridone-carboxylate, ou sel de celui-ci, et antibacterien le contenant comme principe actif |
CA2211681C (en) | 1995-01-30 | 2003-05-13 | Wakunaga Seiyaku Kabushiki Kaisha | Novel pyridonecarboxylic acid derivatives or salts thereof and antibacterial agents comprising the same as active ingredient |
CA2223404C (en) | 1995-06-06 | 2001-01-16 | Thomas A. Morris | Novel crystal form of anhydrous 7-(¬1.alpha., 5.alpha., 6.alpha.|-6-amino-3-azabicyclo¬3.1.0|hex-3-yl)-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid, methanesulfonic acid salt |
US20020032216A1 (en) * | 1997-03-21 | 2002-03-14 | Lg Chemical Ltd. | Salt of naphthyridine carboxylic acid derivative |
KR100286874B1 (ko) * | 1998-03-04 | 2001-04-16 | 성재갑 | 보호된 4-아미노메틸-피롤리딘-3-온의 제조방법 |
GB9820405D0 (en) | 1998-09-18 | 1998-11-11 | Smithkline Beecham Plc | Process |
-
1998
- 1998-03-17 MA MA25001A patent/MA24500A1/fr unknown
- 1998-03-18 DZ DZ980058A patent/DZ2448A1/xx active
- 1998-03-19 ZA ZA9802335A patent/ZA982335B/xx unknown
- 1998-03-20 EP EP01203507A patent/EP1179533B1/en not_active Expired - Lifetime
- 1998-03-20 PL PL335812A patent/PL191815B1/pl unknown
- 1998-03-20 HU HU0000728A patent/HU225412B1/hu unknown
- 1998-03-20 ES ES01203507T patent/ES2213669T3/es not_active Expired - Lifetime
- 1998-03-20 UA UA99095186A patent/UA56218C2/uk unknown
- 1998-03-20 EP EP98908300A patent/EP0981527B1/en not_active Expired - Lifetime
- 1998-03-20 PT PT01203507T patent/PT1179533E/pt unknown
- 1998-03-20 SK SK1236-99A patent/SK284107B6/sk not_active IP Right Cessation
- 1998-03-20 EA EA199900855A patent/EA001674B1/ru not_active IP Right Cessation
- 1998-03-20 DE DE69821147T patent/DE69821147T2/de not_active Expired - Lifetime
- 1998-03-20 PT PT98908300T patent/PT981527E/pt unknown
- 1998-03-20 CA CA002283671A patent/CA2283671C/en not_active Expired - Lifetime
- 1998-03-20 BR BR9808290-6A patent/BR9808290A/pt not_active Application Discontinuation
- 1998-03-20 IL IL131812A patent/IL131812A/en not_active IP Right Cessation
- 1998-03-20 PE PE1998000202A patent/PE67999A1/es not_active Application Discontinuation
- 1998-03-20 KR KR1019980009717A patent/KR100266499B1/ko not_active Expired - Lifetime
- 1998-03-20 AP APAP/P/1999/001649A patent/AP1331A/en active
- 1998-03-20 NZ NZ337748A patent/NZ337748A/xx not_active IP Right Cessation
- 1998-03-20 SI SI9830418T patent/SI0981527T1/xx unknown
- 1998-03-20 HU HU0600401A patent/HU227536B1/hu unknown
- 1998-03-20 CZ CZ19993282A patent/CZ288673B6/cs not_active IP Right Cessation
- 1998-03-20 AT AT01203507T patent/ATE257836T1/de active
- 1998-03-20 AR ARP980101268A patent/AR012125A1/es active IP Right Grant
- 1998-03-20 DK DK01203507T patent/DK1179533T3/da active
- 1998-03-20 ID IDW991044A patent/ID22681A/id unknown
- 1998-03-20 AU AU66366/98A patent/AU726634B2/en not_active Expired
- 1998-03-20 CN CN98803576A patent/CN1131229C/zh not_active Expired - Lifetime
- 1998-03-20 WO PCT/KR1998/000051 patent/WO1998042705A1/en active IP Right Grant
- 1998-03-20 ES ES98908300T patent/ES2198697T3/es not_active Expired - Lifetime
- 1998-03-20 SI SI9830595T patent/SI1179533T1/ unknown
- 1998-03-20 DK DK98908300T patent/DK0981527T3/da active
- 1998-03-20 JP JP54550098A patent/JP3759962B2/ja not_active Expired - Lifetime
- 1998-03-20 TR TR1999/02313T patent/TR199902313T2/xx unknown
- 1998-03-20 DE DE69814378T patent/DE69814378T2/de not_active Expired - Lifetime
- 1998-03-20 AT AT98908300T patent/ATE239724T1/de active
- 1998-03-20 IL IL13181298A patent/IL131812A0/xx active IP Right Grant
- 1998-03-21 MY MYPI98001236A patent/MY137653A/en unknown
- 1998-03-23 IN IN727DE1998 patent/IN188178B/en unknown
- 1998-03-25 SA SA98181055A patent/SA98181055B1/ar unknown
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1999
- 1999-09-14 IS IS5181A patent/IS2093B/is unknown
- 1999-09-20 OA OA9900213A patent/OA11161A/fr unknown
- 1999-09-21 NO NO19994595A patent/NO312515B1/no not_active IP Right Cessation
- 1999-09-21 BG BG103750A patent/BG63972B1/bg unknown
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2000
- 2000-10-03 CZ CZ20003641A patent/CZ288715B6/cs not_active IP Right Cessation
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2003
- 2003-05-07 JP JP2003128650A patent/JP4781614B2/ja not_active Expired - Lifetime
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2005
- 2005-07-21 IS IS7952A patent/IS2095B/is unknown
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2006
- 2006-12-07 US US11/635,069 patent/US7700617B2/en not_active Expired - Fee Related
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2008
- 2008-10-14 JP JP2008265345A patent/JP2009051851A/ja not_active Withdrawn
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2009
- 2009-01-09 US US12/318,845 patent/US20090182006A1/en not_active Abandoned
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2010
- 2010-06-02 US US12/791,957 patent/US20100240694A1/en not_active Abandoned
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2011
- 2011-04-11 US US13/083,685 patent/US20110312987A1/en not_active Abandoned
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2012
- 2012-06-26 US US13/533,383 patent/US20130065917A1/en not_active Abandoned
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2013
- 2013-10-25 US US14/063,117 patent/US20140187576A1/en not_active Abandoned
-
2015
- 2015-02-13 US US14/621,689 patent/US20150291585A1/en not_active Abandoned
-
2016
- 2016-01-15 US US14/996,765 patent/US20160264569A1/en not_active Abandoned
-
2017
- 2017-01-20 US US15/411,030 patent/US20170253588A1/en not_active Abandoned
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