AR006340A1 - Derivados de 2-(3h)-oxazolona, proceso para prepararlos, composiciones farmaceuticas que los incluyan y uso de dichos derivados para tratamientosmedicinales. - Google Patents

Derivados de 2-(3h)-oxazolona, proceso para prepararlos, composiciones farmaceuticas que los incluyan y uso de dichos derivados para tratamientosmedicinales.

Info

Publication number
AR006340A1
AR006340A1 ARP970101133A ARP970101133A AR006340A1 AR 006340 A1 AR006340 A1 AR 006340A1 AR P970101133 A ARP970101133 A AR P970101133A AR P970101133 A ARP970101133 A AR P970101133A AR 006340 A1 AR006340 A1 AR 006340A1
Authority
AR
Argentina
Prior art keywords
derivatives
oxazolone
pharmaceutical compositions
compounds
alkyl
Prior art date
Application number
ARP970101133A
Other languages
English (en)
Original Assignee
Alminana Domenech Nuria
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8294266&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR006340(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alminana Domenech Nuria filed Critical Alminana Domenech Nuria
Publication of AR006340A1 publication Critical patent/AR006340A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/36—One oxygen atom
    • C07D263/38—One oxygen atom attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Se describen compuestos de 2-(3H)-oxazolona de fórmula (I), en donde: R1 es un grupo alquilo o -NR4R5, en donde R4 y R5 cada uno independientementees hidrógeno o un grupo alquilo o bencilo; R2 es un grupo naftilo, tetrahidronaftilo,f enilo no sustituido por 1 a 3 átomos de halógeno, o gruposalquilo, hidroxi, alcoxi o trifluorometilo; y R3 es un hidrógeno o un grupo alquilo. También se preparan composiciones farmacéuticas que incluyen dichoscompuestos como agente activo; unpr ocedimiento para preparar dichos compuestos y el uso de los mismos, para preparar medicamentos para eltratamiento del dolor, la fiebre o inflamación, para inhibir la contracción del músculo liso inducido por prostanoides o para laprev ención del cáncercolorrectal.
ARP970101133A 1996-03-21 1997-03-21 Derivados de 2-(3h)-oxazolona, proceso para prepararlos, composiciones farmaceuticas que los incluyan y uso de dichos derivados para tratamientosmedicinales. AR006340A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES009600685A ES2125161B1 (es) 1996-03-21 1996-03-21 Nuevos derivados de 2-(3h)-oxazolona.

Publications (1)

Publication Number Publication Date
AR006340A1 true AR006340A1 (es) 1999-08-25

Family

ID=8294266

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP970101133A AR006340A1 (es) 1996-03-21 1997-03-21 Derivados de 2-(3h)-oxazolona, proceso para prepararlos, composiciones farmaceuticas que los incluyan y uso de dichos derivados para tratamientosmedicinales.

Country Status (30)

Country Link
US (1) US6869968B1 (es)
EP (1) EP0888316B1 (es)
JP (1) JP3810091B2 (es)
KR (1) KR100496395B1 (es)
CN (1) CN1110488C (es)
AR (1) AR006340A1 (es)
AT (1) ATE197294T1 (es)
AU (1) AU713811B2 (es)
BR (1) BR9708141A (es)
CA (1) CA2249420A1 (es)
CO (1) CO4780046A1 (es)
CZ (1) CZ294963B6 (es)
DE (1) DE69703437T2 (es)
DK (1) DK0888316T3 (es)
ES (2) ES2125161B1 (es)
GR (1) GR3035096T3 (es)
HK (1) HK1015371A1 (es)
ID (1) ID16778A (es)
IL (1) IL126206A (es)
NO (1) NO311761B1 (es)
NZ (1) NZ331901A (es)
PE (1) PE42898A1 (es)
PL (1) PL188722B1 (es)
PT (1) PT888316E (es)
RU (1) RU2194043C2 (es)
TW (1) TW426674B (es)
UA (1) UA52645C2 (es)
UY (1) UY24499A1 (es)
WO (1) WO1997034882A1 (es)
ZA (1) ZA972203B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2125161B1 (es) 1996-03-21 1999-11-16 Grupo Farmaceutico Almirall S Nuevos derivados de 2-(3h)-oxazolona.
FR2753449B1 (fr) * 1996-09-13 1998-12-04 Union Pharma Scient Appl Nouveaux derives 3,4-diaryloxazolone, leurs procedes de preparation, et leurs utilisations en therapeutique
ES2131015B1 (es) * 1997-09-12 2000-03-01 Almirall Prodesfarma Sa Nuevos derivados de 2-(3h)-oxazolona, procedimientos para su preparacion y su empleo en composiciones farmaceuticas.
ES2168895A1 (es) * 1999-03-26 2002-06-16 Almirall Prodesfarma Sa Derivados de 2-fenilpiran-4-ona.
ES2154561B1 (es) * 1998-09-25 2001-12-01 Almirall Prodesfarma Sa Derivados de 2-fenilpiran-4-ona.
WO2001045703A1 (en) 1999-12-23 2001-06-28 Nitromed, Inc. Nitrosated and nitrosylated cyclooxygenase-2 inhibitors, compositions and methods of use
US20030105144A1 (en) 2001-04-17 2003-06-05 Ping Gao Stabilized oral pharmaceutical composition
EP1539679A4 (en) 2002-06-28 2007-07-04 Nitromed Inc OXIM- AND / OR HYDRAZO-CONTAINING, NITROSED AND / OR NITROSYLATED CYCLOOXIGENASE-2 SELECTIVE INHIBITORS, COMPOSITIONS AND USE METHODS
ES2215474B1 (es) 2002-12-24 2005-12-16 J. URIACH & CIA S.A. Nuevos derivados de fosforamida.
ES2213485B1 (es) 2003-02-13 2005-12-16 Almirall Prodesfarma, S.A. Derivados de la 2-fenilpiran-4-ona.
EP1534305B9 (en) 2003-05-07 2007-03-07 Osteologix A/S Treating cartilage / bone conditions with water-soluble strontium salts
CN1309717C (zh) * 2003-06-03 2007-04-11 李小虎 4－芳基－5h－噻吩－2－酮衍生物、其制法和用途
CA2676413A1 (en) * 2007-01-19 2008-07-31 Mallinckrodt Inc. Diagnostic and therapeutic cyclooxygenase-2 binding ligands
CA3209491A1 (en) 2021-03-15 2022-09-22 Saul Yedgar Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4866182A (en) 1988-02-18 1989-09-12 Merrell Dow Pharmaceuticals Inc. Cardiotonic alkanoyl and aroyl oxazolones
US5380738A (en) * 1993-05-21 1995-01-10 Monsanto Company 2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents
DE4435547A1 (de) 1994-10-05 1996-04-11 Bayer Ag Sulfonylaminocarbonyltriazolinone mit über Sauerstoff und Schwefel gebundenen Substituenten
JP2636819B2 (ja) 1994-12-20 1997-07-30 日本たばこ産業株式会社 オキサゾール系複素環式芳香族化合物
ES2125161B1 (es) 1996-03-21 1999-11-16 Grupo Farmaceutico Almirall S Nuevos derivados de 2-(3h)-oxazolona.
FR2753449B1 (fr) * 1996-09-13 1998-12-04 Union Pharma Scient Appl Nouveaux derives 3,4-diaryloxazolone, leurs procedes de preparation, et leurs utilisations en therapeutique

Also Published As

Publication number Publication date
US6869968B1 (en) 2005-03-22
CO4780046A1 (es) 1999-05-26
DE69703437T2 (de) 2001-03-08
JP2000506876A (ja) 2000-06-06
HK1015371A1 (en) 1999-10-15
EP0888316B1 (en) 2000-11-02
EP0888316A1 (en) 1999-01-07
IL126206A (en) 2001-06-14
NZ331901A (en) 1999-10-28
UA52645C2 (uk) 2003-01-15
GR3035096T3 (en) 2001-03-30
AU713811B2 (en) 1999-12-09
CN1218459A (zh) 1999-06-02
NO311761B1 (no) 2002-01-21
CA2249420A1 (en) 1997-09-25
JP3810091B2 (ja) 2006-08-16
CZ294963B6 (cs) 2005-04-13
PL188722B1 (pl) 2005-04-29
KR20000064727A (ko) 2000-11-06
KR100496395B1 (ko) 2005-09-27
DE69703437D1 (de) 2000-12-07
NO984325D0 (no) 1998-09-17
ATE197294T1 (de) 2000-11-15
CN1110488C (zh) 2003-06-04
UY24499A1 (es) 1997-04-02
ES2125161A1 (es) 1999-02-16
MX9701944A (es) 1998-06-30
ZA972203B (en) 1997-09-25
RU2194043C2 (ru) 2002-12-10
AU2289397A (en) 1997-10-10
WO1997034882A1 (en) 1997-09-25
BR9708141A (pt) 1999-07-27
ES2151254T3 (es) 2000-12-16
PE42898A1 (es) 1998-08-12
NO984325L (no) 1998-11-23
CZ297998A3 (cs) 1999-02-17
PL328915A1 (en) 1999-03-01
IL126206A0 (en) 1999-05-09
ID16778A (id) 1997-11-13
TW426674B (en) 2001-03-21
PT888316E (pt) 2001-02-28
DK0888316T3 (da) 2000-11-27
ES2125161B1 (es) 1999-11-16

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Legal Events

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FA Abandonment or withdrawal