FR2753449B1 - Nouveaux derives 3,4-diaryloxazolone, leurs procedes de preparation, et leurs utilisations en therapeutique - Google Patents

Nouveaux derives 3,4-diaryloxazolone, leurs procedes de preparation, et leurs utilisations en therapeutique

Info

Publication number
FR2753449B1
FR2753449B1 FR9611188A FR9611188A FR2753449B1 FR 2753449 B1 FR2753449 B1 FR 2753449B1 FR 9611188 A FR9611188 A FR 9611188A FR 9611188 A FR9611188 A FR 9611188A FR 2753449 B1 FR2753449 B1 FR 2753449B1
Authority
FR
France
Prior art keywords
diaryloxazolone
derivatives
novel
processes
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9611188A
Other languages
English (en)
Other versions
FR2753449A1 (fr
Inventor
Eric Sartori
Jean Marie Charles Teulon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UNION PHARMA SCIENT APPL
UPSA SAS
Original Assignee
UNION PHARMA SCIENT APPL
UPSA SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9495717&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2753449(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by UNION PHARMA SCIENT APPL, UPSA SAS filed Critical UNION PHARMA SCIENT APPL
Priority to FR9611188A priority Critical patent/FR2753449B1/fr
Priority to US08/822,520 priority patent/US5866596A/en
Priority to AU40188/97A priority patent/AU4018897A/en
Priority to PCT/FR1997/001491 priority patent/WO1998011080A1/fr
Priority to ZA9708089A priority patent/ZA978089B/xx
Priority to ARP970104142A priority patent/AR013608A1/es
Priority to TW086113257A priority patent/TW460470B/zh
Publication of FR2753449A1 publication Critical patent/FR2753449A1/fr
Publication of FR2753449B1 publication Critical patent/FR2753449B1/fr
Application granted granted Critical
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/36—One oxygen atom
    • C07D263/38—One oxygen atom attached in position 2
FR9611188A 1996-09-13 1996-09-13 Nouveaux derives 3,4-diaryloxazolone, leurs procedes de preparation, et leurs utilisations en therapeutique Expired - Lifetime FR2753449B1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FR9611188A FR2753449B1 (fr) 1996-09-13 1996-09-13 Nouveaux derives 3,4-diaryloxazolone, leurs procedes de preparation, et leurs utilisations en therapeutique
US08/822,520 US5866596A (en) 1996-09-13 1997-03-24 3,4-diaryloxazolone derivatives, their methods of preparation and their uses in therapeutics
AU40188/97A AU4018897A (en) 1996-09-13 1997-08-14 Novel 3,4-diaryloxazolone derivatives, methods of preparation and therapeutic uses thereof
PCT/FR1997/001491 WO1998011080A1 (fr) 1996-09-13 1997-08-14 Nouveaux derives 3,4-diaryloxazolone, leurs procedes de preparation, et leurs utilisations en therapeutique
ZA9708089A ZA978089B (en) 1996-09-13 1997-09-09 3,4-diaryloxazolone derivatives, their methods of preparation, and their use in therapeutics.
ARP970104142A AR013608A1 (es) 1996-09-13 1997-09-10 Derivados de 3,4-diariloxazolona, procedimiento para su preparacion, y composicion farmaceutica que los comprende.
TW086113257A TW460470B (en) 1996-09-13 1997-09-12 3,4-diaryloxazolone derivatives, their methods of preparation and their uses in therapeutics

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9611188A FR2753449B1 (fr) 1996-09-13 1996-09-13 Nouveaux derives 3,4-diaryloxazolone, leurs procedes de preparation, et leurs utilisations en therapeutique

Publications (2)

Publication Number Publication Date
FR2753449A1 FR2753449A1 (fr) 1998-03-20
FR2753449B1 true FR2753449B1 (fr) 1998-12-04

Family

ID=9495717

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9611188A Expired - Lifetime FR2753449B1 (fr) 1996-09-13 1996-09-13 Nouveaux derives 3,4-diaryloxazolone, leurs procedes de preparation, et leurs utilisations en therapeutique

Country Status (7)

Country Link
US (1) US5866596A (fr)
AR (1) AR013608A1 (fr)
AU (1) AU4018897A (fr)
FR (1) FR2753449B1 (fr)
TW (1) TW460470B (fr)
WO (1) WO1998011080A1 (fr)
ZA (1) ZA978089B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2125161B1 (es) * 1996-03-21 1999-11-16 Grupo Farmaceutico Almirall S Nuevos derivados de 2-(3h)-oxazolona.
ES2131015B1 (es) * 1997-09-12 2000-03-01 Almirall Prodesfarma Sa Nuevos derivados de 2-(3h)-oxazolona, procedimientos para su preparacion y su empleo en composiciones farmaceuticas.
TNSN99111A1 (fr) * 1998-06-11 2005-11-10 Pfizer Derives de sulfonylbenzene nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant.
US6294558B1 (en) 1999-05-31 2001-09-25 Pfizer Inc. Sulfonylbenzene compounds as anti-inflammatory/analgesic agents
US6727238B2 (en) 1998-06-11 2004-04-27 Pfizer Inc. Sulfonylbenzene compounds as anti-inflammatory/analgesic agents
IL144760A0 (en) * 1999-12-08 2002-06-30 Pharmacia Corp Cyclooxygenase-2 inhibitor compositions having rapid onset of therapeutic effect
AU5754701A (en) * 2000-07-13 2002-01-30 Pharmacia Corp Method of using cox-2 inhibitors in the treatment and prevention of ocular cox-2mediated disorders
PE20020146A1 (es) * 2000-07-13 2002-03-31 Upjohn Co Formulacion oftalmica que comprende un inhibidor de ciclooxigenasa-2 (cox-2)
US7115565B2 (en) * 2001-01-18 2006-10-03 Pharmacia & Upjohn Company Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability
US7695736B2 (en) 2001-04-03 2010-04-13 Pfizer Inc. Reconstitutable parenteral composition
US6673818B2 (en) 2001-04-20 2004-01-06 Pharmacia Corporation Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation
UA80682C2 (en) * 2001-08-06 2007-10-25 Pharmacia Corp Orally deliverable stabilized oral suspension formulation and process for the incresaing physical stability of thixotropic pharmaceutical composition
KR100465455B1 (ko) * 2002-06-24 2005-01-13 씨제이 주식회사 2-티옥소티아졸 유도체, 그 제조방법 및 약제학적 조성물
CA2492066A1 (fr) 2002-06-28 2004-01-08 Nitromed, Inc. Inhibiteurs a selectivite cyclooxygenase-2 nitrosiles et/ou nitroses contenant une oxime et/ou une hydrazone, compositions et methodes d'utilisation correspondantes
DE602004002832T2 (de) 2003-05-07 2007-06-06 Osteologix A/S Behandlung von knorpel/knochen-erkrankungen mit wasserlöslichen strontiumsalzen
EP2114461A2 (fr) * 2007-01-19 2009-11-11 Mallinckrodt Inc. Ligands de liaison à la cycloxygénase-2 diagnostiques et thérapeutiques
IL305573A (en) 2021-03-15 2023-10-01 Saul Yedgar Hyaluronic acid conjugated with dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment or suppression of inflammatory diseases

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH585212A5 (fr) * 1973-07-09 1977-02-28 Serna Ag
GB1507032A (en) * 1974-08-06 1978-04-12 Serono Lab 2-thiol-4,5-diphenyloxazole s-derivatives
DE2655369A1 (de) * 1976-12-03 1978-06-08 Schering Ag 5-(subst. phenyl)-oxazolidinone und deren schwefelanaloga sowie verfahren zu deren herstellung
US4632930A (en) * 1984-11-30 1986-12-30 E. I. Du Pont De Nemours And Company Antihypertensive alkyl-arylimidazole, thiazole and oxazole derivatives
DE3639225A1 (de) * 1986-11-14 1988-05-19 Schering Ag Verwendung von 5-(subst. phenyl)-oxazolidinonderiaten als psychopharmaka
US5380738A (en) * 1993-05-21 1995-01-10 Monsanto Company 2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents
US5474995A (en) * 1993-06-24 1995-12-12 Merck Frosst Canada, Inc. Phenyl heterocycles as cox-2 inhibitors
AU5860396A (en) * 1995-05-19 1996-11-29 G.D. Searle & Co. Substituted oxazoles for the treatment of inflammation
US5643933A (en) * 1995-06-02 1997-07-01 G. D. Searle & Co. Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors
ES2125161B1 (es) * 1996-03-21 1999-11-16 Grupo Farmaceutico Almirall S Nuevos derivados de 2-(3h)-oxazolona.

Also Published As

Publication number Publication date
ZA978089B (en) 1998-03-03
WO1998011080A1 (fr) 1998-03-19
TW460470B (en) 2001-10-21
AU4018897A (en) 1998-04-02
US5866596A (en) 1999-02-02
FR2753449A1 (fr) 1998-03-20
AR013608A1 (es) 2001-01-10

Similar Documents

Publication Publication Date Title
FR2751966B1 (fr) Nouveaux derives 1,2-diarylindoles, leurs procedes de preparation, et leurs utilisations en therapeutique
FR2768733B1 (fr) Nouveaux composes 4,4-dihydroxypyrazolin-5-ones ; leurs procedes de preparation et utilisations cosmetiques
FR2753449B1 (fr) Nouveaux derives 3,4-diaryloxazolone, leurs procedes de preparation, et leurs utilisations en therapeutique
FR2769311B1 (fr) Nouveaux derives 3,4-diarylthiazolin-2-one ou -2-thione, leurs procedes de preparation et leurs utilisations en therapeutique
FR2751964B1 (fr) Nouveaux derives diarylmethylene carbocycliques, leurs procedes de preparation, et leurs utilisations en therapeutique
FR2731708B1 (fr) Derives de piperidine, leur procede de preparation et leur application en therapeutique
FR2747678B1 (fr) Composes derives d'imidazobenzoxazine, leurs procedes de preparation et leurs utilisations en therapeutique
FR2728900B1 (fr) Derives de 3-phenylisoquinolein-1(2h)-one, leur preparation et leur application en therapeutique
FR2682679B1 (fr) Nouveaux derives d'alkylpolyosides, leurs procedes de preparation et applications comme agents de surface.
FR2689508B1 (fr) Derives de l'imidazole, leur procede de preparation et leur application en therapeutique.
FR2747123B1 (fr) Nouveaux derives diarylmethylidene tetrahydrofurane, leurs procedes de preparation, et leurs utilisations en therapeutique
MA22981A1 (fr) Derives de piperidine, leur preparation et leur application en therapeutique.
FR2771093B1 (fr) Derives d'imidazole, leur preparation et leur application en therapeutique
FR2775477B1 (fr) Nouveaux derives diarylmethylene heterocycliques, leurs procedes de preparation et leurs utilisations en therapeutique
FR2779429B1 (fr) Derives d'oxindole, leurs preparations et leurs applications en therapeutique
FR2751647B1 (fr) Derives de benzimidazole, leurs preparations et leurs applications en therapeutique
FR2754256B1 (fr) Nouveaux derives 1,2-diarylmethylenes, leurs procedes de preparation, et leurs utilisations en therapeutique
FR2737494B1 (fr) Derives de benzenesulfonamide, leur preparation et leur application en therapeutique
FR2752839B1 (fr) Derives de benzofurane, leur preparation et leur application en therapeutique
FR2765874B1 (fr) Derives de 6-pyrrolidin-2-ylpyrindines, leur preparation et leur application en therapeutique
FR2772378B1 (fr) Derives d'imidazole, leur preparation et leur application en therapeutique
FR2606015B1 (fr) Derives du benzhydrylthiomethane, leurs procedes de preparation et leurs applications en therapeutique
FR2724382B1 (fr) Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique
FR2742152B1 (fr) Derives de 5-naphtalen-1-yl-1,3-dioxanes, leur preparation et leur application en therapeutique
FR2703354B1 (fr) Derives de 1, 2, 5, 6-tetrahydropyridine, leur procede de preparation et leurs applications en therapeutique.

Legal Events

Date Code Title Description
PLFP Fee payment

Year of fee payment: 20