AR023807A1 - Un agente para tratar el ojo seco y el uso de un compuesto macrolido para preparar composiciones farmaceuticas para el tratamiento del ojo seco - Google Patents
Un agente para tratar el ojo seco y el uso de un compuesto macrolido para preparar composiciones farmaceuticas para el tratamiento del ojo secoInfo
- Publication number
- AR023807A1 AR023807A1 ARP000102060A ARP000102060A AR023807A1 AR 023807 A1 AR023807 A1 AR 023807A1 AR P000102060 A ARP000102060 A AR P000102060A AR P000102060 A ARP000102060 A AR P000102060A AR 023807 A1 AR023807 A1 AR 023807A1
- Authority
- AR
- Argentina
- Prior art keywords
- dry eye
- agent
- pharmaceutical compositions
- compound
- macrolid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
Abstract
La presente provee un agente para tratar el ojo seco, que contiene un compuesto macrolido tal como el FK 506, de formula (1). También se describe el uso dedichos macrolidos para la preparacion de las composiciones farmacéuticas destinadas al tratamiento del ojo seco.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13200999P | 1999-04-30 | 1999-04-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR023807A1 true AR023807A1 (es) | 2002-09-04 |
Family
ID=22452015
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP000102060A AR023807A1 (es) | 1999-04-30 | 2000-04-28 | Un agente para tratar el ojo seco y el uso de un compuesto macrolido para preparar composiciones farmaceuticas para el tratamiento del ojo seco |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP1173177B2 (es) |
JP (2) | JP5036934B2 (es) |
KR (1) | KR20020015316A (es) |
CN (1) | CN1190194C (es) |
AR (1) | AR023807A1 (es) |
AT (1) | ATE281167T1 (es) |
AU (1) | AU777915B2 (es) |
BR (1) | BR0011225A (es) |
CA (1) | CA2372448A1 (es) |
CZ (1) | CZ20013769A3 (es) |
DE (1) | DE60015516T2 (es) |
ES (1) | ES2232439T3 (es) |
HK (2) | HK1043321B (es) |
HU (1) | HUP0200864A3 (es) |
IL (1) | IL146162A0 (es) |
MX (1) | MXPA01010988A (es) |
NO (1) | NO20015288D0 (es) |
NZ (1) | NZ515339A (es) |
PT (1) | PT1173177E (es) |
TR (1) | TR200103119T2 (es) |
TW (1) | TWI230066B (es) |
WO (1) | WO2000066122A1 (es) |
ZA (1) | ZA200108905B (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU777915B2 (en) * | 1999-04-30 | 2004-11-04 | Sucampo Ag | Use of macrolide compounds for the treatment of dry eye |
US20070032853A1 (en) | 2002-03-27 | 2007-02-08 | Hossainy Syed F | 40-O-(2-hydroxy)ethyl-rapamycin coated stent |
CN1259049C (zh) | 2001-07-06 | 2006-06-14 | 苏坎波公司 | 包含白介素-2抑制剂和抗菌剂的局部给药组合物 |
AR038628A1 (es) * | 2002-03-04 | 2005-01-19 | Novartis Ag | Composicion oftalmica |
US20050239813A1 (en) * | 2002-08-09 | 2005-10-27 | Sucampo Pharmaceuticals Inc. | Pharmaceutical compositions comprising fk506 derivatives and their use for the treatment of allergic diseases |
US7354574B2 (en) | 2002-11-07 | 2008-04-08 | Advanced Ocular Systems Limited | Treatment of ocular disease |
US20040198763A1 (en) * | 2003-01-16 | 2004-10-07 | Sucampo Ag | Method of treating dry eye with a macrolide compound |
US20050118344A1 (en) | 2003-12-01 | 2005-06-02 | Pacetti Stephen D. | Temperature controlled crimping |
US7083802B2 (en) * | 2003-07-31 | 2006-08-01 | Advanced Ocular Systems Limited | Treatment of ocular disease |
US7087237B2 (en) | 2003-09-19 | 2006-08-08 | Advanced Ocular Systems Limited | Ocular solutions |
US7083803B2 (en) | 2003-09-19 | 2006-08-01 | Advanced Ocular Systems Limited | Ocular solutions |
JP4249185B2 (ja) | 2003-10-06 | 2009-04-02 | 株式会社オフテクス | 涙液異常の治療のための眼科用組成物 |
US8637070B2 (en) | 2005-02-09 | 2014-01-28 | Santen Pharmaceutical Co., Ltd. | Rapamycin formulations and methods of their use |
PL1904056T3 (pl) | 2005-07-18 | 2009-09-30 | Minu Llc | Zastosowanie makrolidu do przywracania czucia rogówkowego |
EP2001438A2 (en) | 2006-02-09 | 2008-12-17 | Macusight, Inc. | Stable formulations, and methods of their preparation and use |
ES2563288T3 (es) | 2006-03-23 | 2016-03-14 | Santen Pharmaceutical Co., Ltd | Rapamicina en dosis bajas para el tratamiento de enfermedades relacionadas con la permeabilidad vascular |
EP2335735A1 (en) * | 2009-12-14 | 2011-06-22 | Novaliq GmbH | Pharmaceutical composition for treatment of dry eye syndrome |
KR20200069261A (ko) * | 2017-05-30 | 2020-06-16 | 엑시모어 엘티디. | 항생제 마크로라이드를 전달하는 안구건조증을 치료하기 위한 조성물 및 방법 |
WO2020139525A1 (en) | 2018-12-27 | 2020-07-02 | Surface Pharmaceuticals, Inc. | Ophthalmic pharmaceutical compositions and methods for treating ocular surface disease |
EP3691654A4 (en) | 2017-09-25 | 2021-11-24 | Surface Pharmaceuticals, Inc. | OPHTHALMIC PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATMENT OF EYE SURFACE DISEASES |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0406791B1 (en) * | 1989-07-05 | 1995-02-01 | Fujisawa Pharmaceutical Co., Ltd. | Aqueous liquid composition for external use |
WO1992019278A1 (en) * | 1991-04-26 | 1992-11-12 | Kurume University | Use of macrolide compounds for eye diseases |
ZA924953B (en) * | 1991-07-25 | 1993-04-28 | Univ Louisville Res Found | Method of treating ocular inflammation |
AR004480A1 (es) * | 1995-04-06 | 1998-12-16 | Amico Derin C D | Compuestos de ascomicina que poseen actividad antiinflamatoria, pro cedimiento para prepararlos, uso de dichos compuestos para preparar agentesfarmaceuticos y composiciones farmaceuticas que los incluyen |
GB9601120D0 (en) * | 1996-01-19 | 1996-03-20 | Sandoz Ltd | Organic compounds |
EP1067926A2 (en) * | 1998-04-06 | 2001-01-17 | Fujisawa Pharmaceutical Co., Ltd. | Immunosuppressive imidazole derivatives and their combination preparations with tacrolimus or cyclosporins |
NZ507345A (en) * | 1998-04-27 | 2002-12-20 | Fujisawa Pharmaceutical Co | Medicinal compositions |
US6376517B1 (en) * | 1998-08-14 | 2002-04-23 | Gpi Nil Holdings, Inc. | Pipecolic acid derivatives for vision and memory disorders |
AU777915B2 (en) * | 1999-04-30 | 2004-11-04 | Sucampo Ag | Use of macrolide compounds for the treatment of dry eye |
-
2000
- 2000-04-26 AU AU41429/00A patent/AU777915B2/en not_active Ceased
- 2000-04-26 DE DE60015516T patent/DE60015516T2/de not_active Expired - Lifetime
- 2000-04-26 BR BR0011225-9A patent/BR0011225A/pt not_active IP Right Cessation
- 2000-04-26 HU HU0200864A patent/HUP0200864A3/hu unknown
- 2000-04-26 TW TW089107899A patent/TWI230066B/zh not_active IP Right Cessation
- 2000-04-26 AT AT00921047T patent/ATE281167T1/de active
- 2000-04-26 MX MXPA01010988A patent/MXPA01010988A/es active IP Right Grant
- 2000-04-26 CN CNB008067686A patent/CN1190194C/zh not_active Expired - Fee Related
- 2000-04-26 CZ CZ20013769A patent/CZ20013769A3/cs unknown
- 2000-04-26 KR KR1020017013768A patent/KR20020015316A/ko not_active Application Discontinuation
- 2000-04-26 EP EP00921047.7A patent/EP1173177B2/en not_active Expired - Lifetime
- 2000-04-26 CA CA002372448A patent/CA2372448A1/en not_active Abandoned
- 2000-04-26 NZ NZ515339A patent/NZ515339A/xx unknown
- 2000-04-26 ES ES00921047T patent/ES2232439T3/es not_active Expired - Lifetime
- 2000-04-26 PT PT00921047T patent/PT1173177E/pt unknown
- 2000-04-26 JP JP2000615007A patent/JP5036934B2/ja not_active Expired - Fee Related
- 2000-04-26 TR TR2001/03119T patent/TR200103119T2/xx unknown
- 2000-04-26 IL IL14616200A patent/IL146162A0/xx unknown
- 2000-04-26 WO PCT/JP2000/002756 patent/WO2000066122A1/en not_active Application Discontinuation
- 2000-04-28 AR ARP000102060A patent/AR023807A1/es not_active Application Discontinuation
-
2001
- 2001-10-29 ZA ZA200108905A patent/ZA200108905B/xx unknown
- 2001-10-29 NO NO20015288A patent/NO20015288D0/no not_active Application Discontinuation
-
2002
- 2002-07-12 HK HK02105192.3A patent/HK1043321B/zh not_active IP Right Cessation
- 2002-10-24 HK HK02107726.4A patent/HK1046099A1/zh unknown
-
2012
- 2012-02-03 JP JP2012022420A patent/JP2012116857A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ZA200108905B (en) | 2002-12-24 |
JP2002543132A (ja) | 2002-12-17 |
EP1173177A1 (en) | 2002-01-23 |
CA2372448A1 (en) | 2000-11-09 |
HK1046099A1 (zh) | 2002-12-27 |
TWI230066B (en) | 2005-04-01 |
WO2000066122A1 (en) | 2000-11-09 |
PT1173177E (pt) | 2005-03-31 |
MXPA01010988A (es) | 2004-04-21 |
NZ515339A (en) | 2004-02-27 |
HK1043321A1 (en) | 2002-09-13 |
HUP0200864A2 (hu) | 2002-07-29 |
DE60015516D1 (de) | 2004-12-09 |
DE60015516T2 (de) | 2005-12-01 |
CN1190194C (zh) | 2005-02-23 |
JP5036934B2 (ja) | 2012-09-26 |
EP1173177B2 (en) | 2014-03-05 |
NO20015288L (no) | 2001-10-29 |
JP2012116857A (ja) | 2012-06-21 |
IL146162A0 (en) | 2002-07-25 |
CN1353608A (zh) | 2002-06-12 |
AU4142900A (en) | 2000-11-17 |
ES2232439T3 (es) | 2005-06-01 |
TR200103119T2 (tr) | 2002-04-22 |
CZ20013769A3 (cs) | 2002-03-13 |
HK1043321B (zh) | 2005-07-15 |
HUP0200864A3 (en) | 2004-07-28 |
NO20015288D0 (no) | 2001-10-29 |
BR0011225A (pt) | 2002-03-19 |
AU777915B2 (en) | 2004-11-04 |
EP1173177B1 (en) | 2004-11-03 |
KR20020015316A (ko) | 2002-02-27 |
ATE281167T1 (de) | 2004-11-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |