HK1043321B - 應用大環內酯化合物治療乾眼癥 - Google Patents

應用大環內酯化合物治療乾眼癥

Info

Publication number
HK1043321B
HK1043321B HK02105192.3A HK02105192A HK1043321B HK 1043321 B HK1043321 B HK 1043321B HK 02105192 A HK02105192 A HK 02105192A HK 1043321 B HK1043321 B HK 1043321B
Authority
HK
Hong Kong
Prior art keywords
treatment
dry eye
macrolide compounds
macrolide
compounds
Prior art date
Application number
HK02105192.3A
Other languages
English (en)
Other versions
HK1043321A1 (en
Inventor
Ueno Ryuji
Original Assignee
蘇坎波公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22452015&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1043321(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 蘇坎波公司 filed Critical 蘇坎波公司
Publication of HK1043321A1 publication Critical patent/HK1043321A1/xx
Publication of HK1043321B publication Critical patent/HK1043321B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
HK02105192.3A 1999-04-30 2002-07-12 應用大環內酯化合物治療乾眼癥 HK1043321B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13200999P 1999-04-30 1999-04-30
PCT/JP2000/002756 WO2000066122A1 (en) 1999-04-30 2000-04-26 Use of macrolide compounds for the treatment of dry eye

Publications (2)

Publication Number Publication Date
HK1043321A1 HK1043321A1 (en) 2002-09-13
HK1043321B true HK1043321B (zh) 2005-07-15

Family

ID=22452015

Family Applications (2)

Application Number Title Priority Date Filing Date
HK02105192.3A HK1043321B (zh) 1999-04-30 2002-07-12 應用大環內酯化合物治療乾眼癥
HK02107726.4A HK1046099A1 (zh) 1999-04-30 2002-10-24 用於治療乾眼的大環內酯化合物的應用

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK02107726.4A HK1046099A1 (zh) 1999-04-30 2002-10-24 用於治療乾眼的大環內酯化合物的應用

Country Status (23)

Country Link
EP (1) EP1173177B2 (zh)
JP (2) JP5036934B2 (zh)
KR (1) KR20020015316A (zh)
CN (1) CN1190194C (zh)
AR (1) AR023807A1 (zh)
AT (1) ATE281167T1 (zh)
AU (1) AU777915B2 (zh)
BR (1) BR0011225A (zh)
CA (1) CA2372448A1 (zh)
CZ (1) CZ20013769A3 (zh)
DE (1) DE60015516T2 (zh)
ES (1) ES2232439T3 (zh)
HK (2) HK1043321B (zh)
HU (1) HUP0200864A3 (zh)
IL (1) IL146162A0 (zh)
MX (1) MXPA01010988A (zh)
NO (1) NO20015288L (zh)
NZ (1) NZ515339A (zh)
PT (1) PT1173177E (zh)
TR (1) TR200103119T2 (zh)
TW (1) TWI230066B (zh)
WO (1) WO2000066122A1 (zh)
ZA (1) ZA200108905B (zh)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2232439T3 (es) * 1999-04-30 2005-06-01 Sucampo Ag Uso de compuestos macrolidos para el tratamiento de los ojos secos.
US20070032853A1 (en) 2002-03-27 2007-02-08 Hossainy Syed F 40-O-(2-hydroxy)ethyl-rapamycin coated stent
US7033604B2 (en) 2001-07-06 2006-04-25 Sucampo Ag Composition for topical administration
AR038628A1 (es) * 2002-03-04 2005-01-19 Novartis Ag Composicion oftalmica
CN1674896A (zh) * 2002-08-09 2005-09-28 苏坎波制药有限公司 含有fk506衍生物的药物组合物及其用于治疗过敏性疾病的用途
US7354574B2 (en) 2002-11-07 2008-04-08 Advanced Ocular Systems Limited Treatment of ocular disease
WO2004062669A1 (en) * 2003-01-16 2004-07-29 Sucampo Ag Use of a macrolide compound for treating dry eye
US20050118344A1 (en) 2003-12-01 2005-06-02 Pacetti Stephen D. Temperature controlled crimping
US7083802B2 (en) 2003-07-31 2006-08-01 Advanced Ocular Systems Limited Treatment of ocular disease
US7083803B2 (en) 2003-09-19 2006-08-01 Advanced Ocular Systems Limited Ocular solutions
US7087237B2 (en) 2003-09-19 2006-08-08 Advanced Ocular Systems Limited Ocular solutions
CA2541302A1 (en) 2003-10-06 2005-04-14 Ophtecs Corporation Ophthalmic composition for treating tear dysfunction
CA2597590A1 (en) 2005-02-09 2006-08-17 Macusight, Inc. Formulations for ocular treatment
PL1904056T3 (pl) 2005-07-18 2009-09-30 Minu Llc Zastosowanie makrolidu do przywracania czucia rogówkowego
US8492400B2 (en) 2006-02-09 2013-07-23 Santen Pharmaceutical Co., Ltd. Stable formulations, and methods of their preparation and use
CN103127100A (zh) 2006-03-23 2013-06-05 参天制药株式会社 用于与血管通透性有关的疾病或病症的制剂和方法
EP2335735A1 (en) * 2009-12-14 2011-06-22 Novaliq GmbH Pharmaceutical composition for treatment of dry eye syndrome
CA3065474A1 (en) * 2017-05-30 2018-12-06 Eximore Ltd. Compositions and methods for treating dry eye syndrome delivering antibiotic macrolide
US11766421B2 (en) 2017-09-25 2023-09-26 Surface Ophthalmics, Inc. Ophthalmic pharmaceutical compositions and methods for treating ocular surface disease
AU2019417161B2 (en) 2018-12-27 2023-06-15 Surface Ophthalmics, Inc. Ophthalmic pharmaceutical compositions and methods for treating ocular surface disease

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0406791T3 (da) * 1989-07-05 1995-03-27 Fujisawa Pharmaceutical Co Vandigt flydende præparat til ekstern anvendelse
DK0581959T3 (da) * 1991-04-26 2001-01-29 Fujisawa Pharmaceutical Co Anvendelse af makrolidforbindelser til øjensygdomme
ZA924953B (en) * 1991-07-25 1993-04-28 Univ Louisville Res Found Method of treating ocular inflammation
AR004480A1 (es) * 1995-04-06 1998-12-16 Amico Derin C D Compuestos de ascomicina que poseen actividad antiinflamatoria, pro cedimiento para prepararlos, uso de dichos compuestos para preparar agentesfarmaceuticos y composiciones farmaceuticas que los incluyen
GB9601120D0 (en) * 1996-01-19 1996-03-20 Sandoz Ltd Organic compounds
US6673807B1 (en) * 1998-04-06 2004-01-06 Fujisawa Pharmaceutical Co., Ltd. Immunosuppressive imidazole derivatives and their combination preparations with tacrolimus or cyclosporins
JP3732525B2 (ja) * 1998-04-27 2006-01-05 アステラス製薬株式会社 医薬組成物
US6376517B1 (en) * 1998-08-14 2002-04-23 Gpi Nil Holdings, Inc. Pipecolic acid derivatives for vision and memory disorders
ES2232439T3 (es) * 1999-04-30 2005-06-01 Sucampo Ag Uso de compuestos macrolidos para el tratamiento de los ojos secos.

Also Published As

Publication number Publication date
DE60015516D1 (de) 2004-12-09
EP1173177B1 (en) 2004-11-03
CZ20013769A3 (cs) 2002-03-13
HUP0200864A2 (hu) 2002-07-29
JP2012116857A (ja) 2012-06-21
NO20015288D0 (no) 2001-10-29
IL146162A0 (en) 2002-07-25
AU4142900A (en) 2000-11-17
BR0011225A (pt) 2002-03-19
CA2372448A1 (en) 2000-11-09
ZA200108905B (en) 2002-12-24
KR20020015316A (ko) 2002-02-27
AU777915B2 (en) 2004-11-04
EP1173177B2 (en) 2014-03-05
DE60015516T2 (de) 2005-12-01
CN1190194C (zh) 2005-02-23
TWI230066B (en) 2005-04-01
PT1173177E (pt) 2005-03-31
JP5036934B2 (ja) 2012-09-26
CN1353608A (zh) 2002-06-12
ATE281167T1 (de) 2004-11-15
HK1046099A1 (zh) 2002-12-27
WO2000066122A1 (en) 2000-11-09
AR023807A1 (es) 2002-09-04
EP1173177A1 (en) 2002-01-23
HK1043321A1 (en) 2002-09-13
TR200103119T2 (tr) 2002-04-22
ES2232439T3 (es) 2005-06-01
HUP0200864A3 (en) 2004-07-28
NO20015288L (no) 2001-10-29
JP2002543132A (ja) 2002-12-17
MXPA01010988A (es) 2004-04-21
NZ515339A (en) 2004-02-27

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090426