HK1046099A1 - 用於治療乾眼的大環內酯化合物的應用 - Google Patents

用於治療乾眼的大環內酯化合物的應用

Info

Publication number
HK1046099A1
HK1046099A1 HK02107726.4A HK02107726A HK1046099A1 HK 1046099 A1 HK1046099 A1 HK 1046099A1 HK 02107726 A HK02107726 A HK 02107726A HK 1046099 A1 HK1046099 A1 HK 1046099A1
Authority
HK
Hong Kong
Prior art keywords
treatment
dry eye
macrolide compounds
macrolide
compounds
Prior art date
Application number
HK02107726.4A
Other languages
English (en)
Inventor
Ueno Ryuji
Original Assignee
蘇坎波公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22452015&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1046099(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 蘇坎波公司 filed Critical 蘇坎波公司
Publication of HK1046099A1 publication Critical patent/HK1046099A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
HK02107726.4A 1999-04-30 2002-10-24 用於治療乾眼的大環內酯化合物的應用 HK1046099A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13200999P 1999-04-30 1999-04-30
PCT/JP2000/002756 WO2000066122A1 (en) 1999-04-30 2000-04-26 Use of macrolide compounds for the treatment of dry eye

Publications (1)

Publication Number Publication Date
HK1046099A1 true HK1046099A1 (zh) 2002-12-27

Family

ID=22452015

Family Applications (2)

Application Number Title Priority Date Filing Date
HK02105192.3A HK1043321B (zh) 1999-04-30 2002-07-12 應用大環內酯化合物治療乾眼癥
HK02107726.4A HK1046099A1 (zh) 1999-04-30 2002-10-24 用於治療乾眼的大環內酯化合物的應用

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK02105192.3A HK1043321B (zh) 1999-04-30 2002-07-12 應用大環內酯化合物治療乾眼癥

Country Status (23)

Country Link
EP (1) EP1173177B2 (zh)
JP (2) JP5036934B2 (zh)
KR (1) KR20020015316A (zh)
CN (1) CN1190194C (zh)
AR (1) AR023807A1 (zh)
AT (1) ATE281167T1 (zh)
AU (1) AU777915B2 (zh)
BR (1) BR0011225A (zh)
CA (1) CA2372448A1 (zh)
CZ (1) CZ20013769A3 (zh)
DE (1) DE60015516T2 (zh)
ES (1) ES2232439T3 (zh)
HK (2) HK1043321B (zh)
HU (1) HUP0200864A3 (zh)
IL (1) IL146162A0 (zh)
MX (1) MXPA01010988A (zh)
NO (1) NO20015288D0 (zh)
NZ (1) NZ515339A (zh)
PT (1) PT1173177E (zh)
TR (1) TR200103119T2 (zh)
TW (1) TWI230066B (zh)
WO (1) WO2000066122A1 (zh)
ZA (1) ZA200108905B (zh)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2232439T3 (es) * 1999-04-30 2005-06-01 Sucampo Ag Uso de compuestos macrolidos para el tratamiento de los ojos secos.
US20070032853A1 (en) 2002-03-27 2007-02-08 Hossainy Syed F 40-O-(2-hydroxy)ethyl-rapamycin coated stent
CN1259049C (zh) 2001-07-06 2006-06-14 苏坎波公司 包含白介素－2抑制剂和抗菌剂的局部给药组合物
PE20030828A1 (es) * 2002-03-04 2003-11-04 Novartis Ag Composicion oftalmica que comprende ascomicina
AU2003256068A1 (en) * 2002-08-09 2004-02-25 Sucampo Pharmaceuticals, Inc. Pharmaceutical compositions comprising fk506 derivatives and the ir use for the treatment of allergic diseases
US7354574B2 (en) 2002-11-07 2008-04-08 Advanced Ocular Systems Limited Treatment of ocular disease
WO2004062669A1 (en) * 2003-01-16 2004-07-29 Sucampo Ag Use of a macrolide compound for treating dry eye
US20050118344A1 (en) 2003-12-01 2005-06-02 Pacetti Stephen D. Temperature controlled crimping
US7083802B2 (en) 2003-07-31 2006-08-01 Advanced Ocular Systems Limited Treatment of ocular disease
US7083803B2 (en) 2003-09-19 2006-08-01 Advanced Ocular Systems Limited Ocular solutions
US7087237B2 (en) 2003-09-19 2006-08-08 Advanced Ocular Systems Limited Ocular solutions
CA2541302A1 (en) 2003-10-06 2005-04-14 Ophtecs Corporation Ophthalmic composition for treating tear dysfunction
AU2006213673A1 (en) 2005-02-09 2006-08-17 Santen Pharmaceutical Co., Ltd. Formulations for ocular treatment
AU2006270041B2 (en) 2005-07-18 2011-08-18 Minu, Llc Enhanced ocular neuroprotection/neurostimulation
CA2635797C (en) 2006-02-09 2015-03-31 Macusight, Inc. Stable formulations, and methods of their preparation and use
JP5506378B2 (ja) 2006-03-23 2014-05-28 参天製薬株式会社 血管透過性に関連する疾患または病気のための製剤および方法
EP2335735A1 (en) * 2009-12-14 2011-06-22 Novaliq GmbH Pharmaceutical composition for treatment of dry eye syndrome
WO2018220444A2 (en) * 2017-05-30 2018-12-06 Eximore Ltd. Compositions and methods for treating dry eye syndrome delivering antibiotic macrolide
US11766421B2 (en) 2017-09-25 2023-09-26 Surface Ophthalmics, Inc. Ophthalmic pharmaceutical compositions and methods for treating ocular surface disease

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA905202B (en) * 1989-07-05 1991-04-24 Fujisawa Pharmaceutical Co Aqueous liquid composition for external use
JP3158437B2 (ja) * 1991-04-26 2001-04-23 藤沢薬品工業株式会社 眼疾患に対するマクロライド化合物の使用
IL102414A (en) * 1991-07-25 1996-08-04 Univ Louisville Res Found Medicinal preparations for the treatment of ocular inflammation, containing rapamycin
AR004480A1 (es) * 1995-04-06 1998-12-16 Amico Derin C D Compuestos de ascomicina que poseen actividad antiinflamatoria, pro cedimiento para prepararlos, uso de dichos compuestos para preparar agentesfarmaceuticos y composiciones farmaceuticas que los incluyen
GB9601120D0 (en) * 1996-01-19 1996-03-20 Sandoz Ltd Organic compounds
US6673807B1 (en) * 1998-04-06 2004-01-06 Fujisawa Pharmaceutical Co., Ltd. Immunosuppressive imidazole derivatives and their combination preparations with tacrolimus or cyclosporins
IL139210A (en) * 1998-04-27 2005-11-20 Fujisawa Pharmaceutical Co Pharmaceutical composition containing a macrolide compound
US6376517B1 (en) * 1998-08-14 2002-04-23 Gpi Nil Holdings, Inc. Pipecolic acid derivatives for vision and memory disorders
ES2232439T3 (es) * 1999-04-30 2005-06-01 Sucampo Ag Uso de compuestos macrolidos para el tratamiento de los ojos secos.

Also Published As

Publication number Publication date
WO2000066122A1 (en) 2000-11-09
HK1043321A1 (en) 2002-09-13
PT1173177E (pt) 2005-03-31
IL146162A0 (en) 2002-07-25
MXPA01010988A (es) 2004-04-21
JP2012116857A (ja) 2012-06-21
CZ20013769A3 (cs) 2002-03-13
CN1353608A (zh) 2002-06-12
DE60015516D1 (de) 2004-12-09
ZA200108905B (en) 2002-12-24
EP1173177B2 (en) 2014-03-05
DE60015516T2 (de) 2005-12-01
TWI230066B (en) 2005-04-01
BR0011225A (pt) 2002-03-19
KR20020015316A (ko) 2002-02-27
EP1173177B1 (en) 2004-11-03
EP1173177A1 (en) 2002-01-23
TR200103119T2 (tr) 2002-04-22
AR023807A1 (es) 2002-09-04
AU4142900A (en) 2000-11-17
JP5036934B2 (ja) 2012-09-26
HUP0200864A2 (hu) 2002-07-29
NO20015288L (no) 2001-10-29
NZ515339A (en) 2004-02-27
CA2372448A1 (en) 2000-11-09
NO20015288D0 (no) 2001-10-29
HUP0200864A3 (en) 2004-07-28
AU777915B2 (en) 2004-11-04
ATE281167T1 (de) 2004-11-15
CN1190194C (zh) 2005-02-23
JP2002543132A (ja) 2002-12-17
ES2232439T3 (es) 2005-06-01
HK1043321B (zh) 2005-07-15

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