AP861A - Substituted N-({Aminoiminomethyl or aminomethyl} phenyl] propyl amides. - Google Patents
Substituted N-({Aminoiminomethyl or aminomethyl} phenyl] propyl amides. Download PDFInfo
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- AP861A AP861A APAP/P/1998/001288A AP9801288A AP861A AP 861 A AP861 A AP 861A AP 9801288 A AP9801288 A AP 9801288A AP 861 A AP861 A AP 861A
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- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
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- C07C255/60—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton at least one of the singly-bound nitrogen atoms being acylated
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- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
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- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/18—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to carbon atoms of six-membered aromatic rings
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- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US948596P | 1996-01-02 | 1996-01-02 | |
PCT/US1996/020770 WO1997024118A1 (en) | 1996-01-02 | 1996-12-23 | Substituted n-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides |
Publications (2)
Publication Number | Publication Date |
---|---|
AP9801288A0 AP9801288A0 (en) | 1998-09-30 |
AP861A true AP861A (en) | 2000-08-01 |
Family
ID=21737952
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
APAP/P/1998/001288A AP861A (en) | 1996-01-02 | 1996-12-23 | Substituted N-({Aminoiminomethyl or aminomethyl} phenyl] propyl amides. |
Country Status (29)
Country | Link |
---|---|
US (1) | US6140504A (cs) |
EP (1) | EP0906094B1 (cs) |
JP (1) | JP4053597B2 (cs) |
KR (1) | KR100348338B1 (cs) |
CN (1) | CN1273128C (cs) |
AP (1) | AP861A (cs) |
AT (1) | ATE243512T1 (cs) |
AU (1) | AU723338B2 (cs) |
BG (1) | BG64143B1 (cs) |
BR (1) | BR9612423B1 (cs) |
CA (1) | CA2241904C (cs) |
CL (1) | CL2004000376A1 (cs) |
CZ (1) | CZ297544B6 (cs) |
DE (1) | DE69628856T2 (cs) |
DK (1) | DK0906094T3 (cs) |
EA (2) | EA001280B1 (cs) |
ES (1) | ES2197257T3 (cs) |
HK (1) | HK1017613A1 (cs) |
HU (1) | HU228355B1 (cs) |
IL (1) | IL125163A0 (cs) |
NO (1) | NO310719B1 (cs) |
OA (1) | OA10804A (cs) |
PL (1) | PL185460B1 (cs) |
PT (1) | PT906094E (cs) |
RO (1) | RO117913B1 (cs) |
SI (2) | SI0906094T1 (cs) |
SK (1) | SK284507B6 (cs) |
UA (1) | UA46821C2 (cs) |
WO (1) | WO1997024118A1 (cs) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6080767A (en) * | 1996-01-02 | 2000-06-27 | Aventis Pharmaceuticals Products Inc. | Substituted n-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides |
ES2197257T3 (es) * | 1996-01-02 | 2004-01-01 | Aventis Pharmaceuticals Inc. | N-[(aminoiminometil o aminometil)fenil-propilamidas sustituidas. |
TW542822B (en) | 1997-01-17 | 2003-07-21 | Ajinomoto Kk | Benzamidine derivatives |
WO1999010317A1 (fr) * | 1997-08-26 | 1999-03-04 | Kumiai Chemical Industry Co., Ltd. | Derives d'acide biarylalkylenecarbamique et bactericides a usage horticole et agricole |
US6740682B2 (en) | 1997-08-29 | 2004-05-25 | Tularik Limited | Meta-benzamidine derivatives as serine protease inhibitors |
HUP0101482A3 (en) * | 1998-03-23 | 2002-12-28 | Aventis Pharm Prod Inc | Piperidinyl and n-amidinopiperidinyl derivatives, use of them for producing pharmaceutical compositions and pharmaceutical compositions containing the same |
CN1311771A (zh) * | 1998-06-08 | 2001-09-05 | 味之素株式会社 | 苯甲脒衍生物 |
AU3127900A (en) | 1998-12-23 | 2000-07-31 | Du Pont Pharmaceuticals Company | Thrombin or factor xa inhibitors |
CA2358091A1 (en) * | 1998-12-23 | 2000-07-06 | Eli Lilly And Company | Antithrombotic amides |
EP1140901A2 (en) | 1998-12-24 | 2001-10-10 | Aventis Pharmaceuticals Products Inc. | Substituted (aminoiminomethyl or aminomethyl)benzoheteroaryl compounds as factor xa inhibitors |
EP1022268A1 (en) * | 1999-01-02 | 2000-07-26 | Aventis Pharma Deutschland GmbH | Arylalkanoyl derivatives, processes for their preparation, their use and pharmaceutical compositions containing them |
CA2358581C (en) * | 1999-01-02 | 2010-02-02 | Aventis Pharma Deutschland Gmbh | Arylalkanoyl derivatives, processes for their preparation, their use and pharmaceutical compositions containing them |
US6794412B1 (en) * | 1999-03-11 | 2004-09-21 | Bristol-Myers Squibb Pharma Company | Treatment of thrombosis by combined use of a factor Xa inhibitor and aspirin |
WO2000076971A2 (en) | 1999-06-14 | 2000-12-21 | Eli Lilly And Company | Serine protease inhibitors |
WO2001030756A1 (fr) * | 1999-10-28 | 2001-05-03 | Sankyo Company, Limited | Derives de benzamidine |
AU1515701A (en) | 1999-11-02 | 2001-05-14 | Aventis Pharma Deutschland Gmbh | Use of russell's viper venom-induced plasma factor xa activity to monitor the activity of factor xa inhibitors |
DE10006601A1 (de) | 2000-02-15 | 2001-08-16 | Clariant Gmbh | Verfahren zur Herstellung von 4-(4'-Carboxyphenyl)pyridin |
GB0108903D0 (en) * | 2000-10-05 | 2001-05-30 | Aventis Pharm Prod Inc | Novel crystalline forms of a factor Xa inhibitor |
CN100513398C (zh) | 2002-12-03 | 2009-07-15 | Axys药物公司 | 作为因子viia抑制剂的2-(2-羟基联苯-3-基)-1h-苯并咪唑-5-甲脒衍生物 |
DE102006048300A1 (de) | 2006-01-26 | 2007-08-02 | Hellstern, Peter, Prof. Dr.med. | Inhibitoren des Blutgerinnungsfaktors Xa zur Verwendung als Antikoagulans |
US8784847B2 (en) * | 2009-04-17 | 2014-07-22 | Merz Pharma Gmbh & Co. Kgaa | Synthesis of 1-amino-1,3,3,5,5,-cyclohexane mesylate |
PE20121401A1 (es) | 2009-07-29 | 2012-10-25 | Sanofi Sa | Otamixaban para el tratamiento de pacientes con alteracion renal y de edad avanzada con infarto de miocardio sin elevacion del st |
GB0919194D0 (en) | 2009-11-02 | 2009-12-16 | Lytix Biopharma As | Compounds |
EA025572B1 (ru) | 2011-03-29 | 2017-01-30 | Санофи | Лекарственные формы отамиксабана с улучшенной стабильностью |
WO2012130821A1 (en) | 2011-03-29 | 2012-10-04 | Sanofi | Benzoic acid salt of otamixaban |
US9120776B2 (en) | 2011-09-22 | 2015-09-01 | Takeda Pharmaceutical Company Limited | Condensed heterocyclic compound |
CN104755080A (zh) | 2012-08-31 | 2015-07-01 | 赛诺菲 | 用于在计划接受冠状动脉旁路移植术的患者中对非st抬高型急性冠状动脉综合征进行治疗的奥米沙班 |
DE102014108210A1 (de) | 2014-06-11 | 2015-12-17 | Dietrich Gulba | Rodentizid |
US10351750B2 (en) | 2017-02-03 | 2019-07-16 | Saudi Arabian Oil Company | Drilling fluid compositions with enhanced rheology and methods of using same |
EP4070658A1 (de) | 2021-04-06 | 2022-10-12 | BIORoxx GmbH | Verwendung von blutgerinnungshemmenden verbindungen als rodentizide |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5424334A (en) * | 1991-12-19 | 1995-06-13 | G. D. Searle & Co. | Peptide mimetic compounds useful as platelet aggregation inhibitors |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2197257T3 (es) * | 1996-01-02 | 2004-01-01 | Aventis Pharmaceuticals Inc. | N-[(aminoiminometil o aminometil)fenil-propilamidas sustituidas. |
-
1996
- 1996-12-23 ES ES96945304T patent/ES2197257T3/es not_active Expired - Lifetime
- 1996-12-23 AU AU15207/97A patent/AU723338B2/en not_active Expired
- 1996-12-23 CA CA002241904A patent/CA2241904C/en not_active Expired - Lifetime
- 1996-12-23 CZ CZ0201098A patent/CZ297544B6/cs not_active IP Right Cessation
- 1996-12-23 KR KR10-1998-0705093A patent/KR100348338B1/ko not_active IP Right Cessation
- 1996-12-23 PT PT96945304T patent/PT906094E/pt unknown
- 1996-12-23 IL IL12516396A patent/IL125163A0/xx not_active IP Right Cessation
- 1996-12-23 EA EA199800620A patent/EA001280B1/ru not_active IP Right Cessation
- 1996-12-23 SI SI9630629T patent/SI0906094T1/xx unknown
- 1996-12-23 HU HU9900930A patent/HU228355B1/hu unknown
- 1996-12-23 BR BRPI9612423-7A patent/BR9612423B1/pt not_active IP Right Cessation
- 1996-12-23 CN CNB961998946A patent/CN1273128C/zh not_active Expired - Lifetime
- 1996-12-23 JP JP52456097A patent/JP4053597B2/ja not_active Expired - Lifetime
- 1996-12-23 SI SI9620136A patent/SI9620136B/sl active Search and Examination
- 1996-12-23 EP EP96945304A patent/EP0906094B1/en not_active Expired - Lifetime
- 1996-12-23 DK DK96945304T patent/DK0906094T3/da active
- 1996-12-23 AT AT96945304T patent/ATE243512T1/de active
- 1996-12-23 AP APAP/P/1998/001288A patent/AP861A/en active
- 1996-12-23 WO PCT/US1996/020770 patent/WO1997024118A1/en active IP Right Grant
- 1996-12-23 DE DE69628856T patent/DE69628856T2/de not_active Expired - Lifetime
- 1996-12-23 SK SK897-98A patent/SK284507B6/sk not_active IP Right Cessation
- 1996-12-23 PL PL96327633A patent/PL185460B1/pl unknown
- 1996-12-23 UA UA98074143A patent/UA46821C2/uk unknown
- 1996-12-23 RO RO98-01136A patent/RO117913B1/ro unknown
- 1996-12-23 EA EA199900669A patent/EA001932B1/ru not_active IP Right Cessation
-
1998
- 1998-06-30 NO NO19983039A patent/NO310719B1/no not_active IP Right Cessation
- 1998-07-01 OA OA9800100A patent/OA10804A/en unknown
- 1998-07-10 BG BG102619A patent/BG64143B1/bg unknown
-
1999
- 1999-07-05 HK HK99102817A patent/HK1017613A1/xx not_active IP Right Cessation
-
2000
- 2000-02-04 US US09/499,335 patent/US6140504A/en not_active Expired - Lifetime
-
2004
- 2004-02-26 CL CL200400376A patent/CL2004000376A1/es unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5424334A (en) * | 1991-12-19 | 1995-06-13 | G. D. Searle & Co. | Peptide mimetic compounds useful as platelet aggregation inhibitors |
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