ZW12889A1 - Pyridine derivatives - Google Patents

Pyridine derivatives

Info

Publication number
ZW12889A1
ZW12889A1 ZW128/89A ZW12889A ZW12889A1 ZW 12889 A1 ZW12889 A1 ZW 12889A1 ZW 128/89 A ZW128/89 A ZW 128/89A ZW 12889 A ZW12889 A ZW 12889A ZW 12889 A1 ZW12889 A1 ZW 12889A1
Authority
ZW
Zimbabwe
Prior art keywords
disease
hydroxy
variety
acid derivatives
dioxane
Prior art date
Application number
ZW128/89A
Other languages
English (en)
Inventor
George Brewster Andrew
Robert Brown George
Wellington Paul Alan
Jessup Reginald
James Smithers Michael
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888824667A external-priority patent/GB8824667D0/en
Priority claimed from GB888824668A external-priority patent/GB8824668D0/en
Priority claimed from GB898918937A external-priority patent/GB8918937D0/en
Application filed by Ici Plc filed Critical Ici Plc
Publication of ZW12889A1 publication Critical patent/ZW12889A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZW128/89A 1988-10-21 1989-10-15 Pyridine derivatives ZW12889A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB888824667A GB8824667D0 (en) 1988-10-21 1988-10-21 Carboxylic acids
GB888824668A GB8824668D0 (en) 1988-10-21 1988-10-21 Alkenoic acids
GB898918937A GB8918937D0 (en) 1989-08-18 1989-08-18 Acid derivatives

Publications (1)

Publication Number Publication Date
ZW12889A1 true ZW12889A1 (en) 1989-12-06

Family

ID=27264134

Family Applications (1)

Application Number Title Priority Date Filing Date
ZW128/89A ZW12889A1 (en) 1988-10-21 1989-10-15 Pyridine derivatives

Country Status (22)

Country Link
US (1) US5053415A (de)
EP (1) EP0365328B1 (de)
JP (1) JPH0699426B2 (de)
KR (1) KR0161260B1 (de)
AT (1) ATE136304T1 (de)
AU (1) AU627230B2 (de)
CA (1) CA2001160C (de)
DE (1) DE68926144T2 (de)
DK (1) DK513789A (de)
ES (1) ES2087868T3 (de)
FI (1) FI93545C (de)
GR (1) GR3019550T3 (de)
HU (2) HU212263B (de)
IE (1) IE81170B1 (de)
IL (1) IL92028A (de)
MY (1) MY104242A (de)
NO (1) NO173735C (de)
PH (1) PH27054A (de)
PL (2) PL163045B1 (de)
PT (1) PT92035B (de)
RU (1) RU2045526C1 (de)
ZW (1) ZW12889A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8901201D0 (en) * 1988-02-16 1989-03-15 Ici Plc Pyridine derivatives
US5248780A (en) * 1988-02-16 1993-09-28 Imperial Chemical Industries, Plc Pyridyl substituted alkenoic acid derivatives
IE66512B1 (en) * 1989-02-28 1996-01-10 Ici Plc Heterocyclic ethers as 5-lipoxygenase inhibitors
GB9021571D0 (en) * 1990-10-04 1990-11-21 Ici Plc Heterocyclic acids
FR2702213B1 (fr) * 1993-03-02 1995-04-07 Rhone Poulenc Rorer Sa Procédé de préparation de N-méthyl (pyridyl-3)-2 tétrahydrothiopyrannecarbothioamide-2-oxyde-1-(1R,2R).
US5371096A (en) * 1993-08-27 1994-12-06 Ciba-Geigy Corporation (3-pyridyl)tetrafuran-2-yl substituted carboxylic acids
US20110178112A1 (en) * 2006-01-18 2011-07-21 Evolva Sa PPAR Modulators
EP2150111B1 (de) 2007-01-18 2016-10-19 Evolva SA Substituierte 1,3-dioxane als ppar-modulatoren
CA2676439A1 (en) 2007-01-18 2008-07-24 Evolva Sa Substituted 1,3-dioxanes and their uses
US9012450B2 (en) 2011-12-28 2015-04-21 Global Blood Therapeutics, Inc. Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
CN104135859B (zh) 2011-12-28 2017-06-27 全球血液疗法公司 取代的苯甲醛化合物及其用于增加组织氧合的方法
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
PE20160078A1 (es) 2013-03-15 2016-03-02 Global Blood Therapeutics Inc Compuestos y sus usos para modular la hemoglobina
US9422279B2 (en) 2013-03-15 2016-08-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
MY183637A (en) 2013-03-15 2021-03-04 Global Blood Therapeutics Inc Compounds and uses thereof for the modulation of hemoglobin
AP2015008721A0 (en) 2013-03-15 2015-09-30 Global Blood Therapeutics Inc Compounds and uses thereof for the modulation of hemoglobin
US10100043B2 (en) 2013-03-15 2018-10-16 Global Blood Therapeutics, Inc. Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
EA201992707A1 (ru) 2013-11-18 2020-06-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
PT3102208T (pt) 2014-02-07 2021-04-05 Global Blood Therapeutics Inc Polimorfos cristalinos da base livre de 2-hidroxi-6-((2-(1-isopropil-1h-pirazol-5-il)piridin-3 il)metoxi)benzaldeído
TW201731509A (zh) 2015-12-04 2017-09-16 全球血液治療公司 針對２-羥基-６-（（２-（１-異丙基-１ｈ-吡唑-５-基）吡啶-３-基）甲氧基）-苯甲醛之劑量方案
AR108435A1 (es) 2016-05-12 2018-08-22 Global Blood Therapeutics Inc Proceso para sintetizar 2-hidroxi-6-((2-(1-isopropil-1h-pirazol-5-il)-piridin-3-il)metoxi)benzaldehído
TW202332423A (zh) 2016-10-12 2023-08-16 美商全球血液治療公司 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
CN106700129B (zh) * 2016-10-20 2018-11-23 北京吉海川科技发展有限公司 一种位阻酚的酯类抗氧化剂及其制备方法和应用
US11014884B2 (en) 2018-10-01 2021-05-25 Global Blood Therapeutics, Inc. Modulators of hemoglobin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8310407D0 (en) * 1982-05-12 1983-05-25 Ici Plc 1 3 - dioxan -5- ylalkenoic acids
GB8330099D0 (en) * 1983-11-11 1983-12-21 Ici Plc Cycloalkane derivatives
US4554011A (en) * 1984-08-24 1985-11-19 Chevron Research Company Herbicidal 2S-(2β,4β,5β)-5-Arylmethoxy-4-substituted 2-alkyl-1,3-dioxane derivatives
GB8511895D0 (en) * 1985-05-10 1985-06-19 Ici Plc Heterocyclic compounds
EP0201352B1 (de) * 1985-05-10 1992-06-24 Imperial Chemical Industries Plc Alkenderivate
GB8511894D0 (en) * 1985-05-10 1985-06-19 Ici Plc Phenol derivatives
AT387860B (de) * 1985-09-16 1989-03-28 Optical Sensing Technology Verfahren und vorrichtung zur tumordiagnose mittels sera
GB8709794D0 (en) * 1987-04-24 1987-05-28 Ici Plc Heterocyclic acids
GB8901201D0 (en) * 1988-02-16 1989-03-15 Ici Plc Pyridine derivatives

Also Published As

Publication number Publication date
AU4293689A (en) 1990-04-26
GR3019550T3 (en) 1996-07-31
JPH02164877A (ja) 1990-06-25
NO894190L (no) 1990-04-23
DK513789A (da) 1990-04-22
HU211522A9 (en) 1995-11-28
PT92035B (pt) 1995-05-31
EP0365328A2 (de) 1990-04-25
PH27054A (en) 1993-02-01
PL163045B1 (pl) 1994-02-28
US5053415A (en) 1991-10-01
MY104242A (en) 1994-02-28
AU627230B2 (en) 1992-08-20
DK513789D0 (da) 1989-10-16
DE68926144T2 (de) 1996-10-17
IE893300L (en) 1990-04-21
PL163178B1 (pl) 1994-02-28
EP0365328B1 (de) 1996-04-03
HU895320D0 (en) 1990-01-28
KR0161260B1 (ko) 1998-12-01
NO894190D0 (no) 1989-10-20
DE68926144D1 (de) 1996-05-09
HU212263B (en) 1996-04-29
CA2001160A1 (en) 1990-04-21
FI895007A0 (fi) 1989-10-20
ES2087868T3 (es) 1996-08-01
NO173735B (no) 1993-10-18
CA2001160C (en) 2000-09-05
IL92028A (en) 1994-06-24
JPH0699426B2 (ja) 1994-12-07
PT92035A (pt) 1990-04-30
KR900006324A (ko) 1990-05-07
IE81170B1 (en) 2000-05-31
IL92028A0 (en) 1990-07-12
NO173735C (no) 1994-01-26
FI93545C (fi) 1995-04-25
HUT58075A (en) 1992-01-28
ATE136304T1 (de) 1996-04-15
PL286429A1 (en) 1991-04-22
FI93545B (fi) 1995-01-13
RU2045526C1 (ru) 1995-10-10
EP0365328A3 (en) 1990-11-28

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