JO1604B1 - Pyridine dervatives - Google Patents

Pyridine dervatives

Info

Publication number
JO1604B1
JO1604B1 JO19891604A JOP19891604A JO1604B1 JO 1604 B1 JO1604 B1 JO 1604B1 JO 19891604 A JO19891604 A JO 19891604A JO P19891604 A JOP19891604 A JO P19891604A JO 1604 B1 JO1604 B1 JO 1604B1
Authority
JO
Jordan
Prior art keywords
disease
hydroxy
variety
acid derivatives
dioxane
Prior art date
Application number
JO19891604A
Other languages
Arabic (ar)
Inventor
جورج بروستر اندرو
ولنغتون فاول الين
روبرت براون جورج
جيسوب رجينالد
Original Assignee
استرازينيكا ايه بي
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by استرازينيكا ايه بي filed Critical استرازينيكا ايه بي
Application granted granted Critical
Publication of JO1604B1 publication Critical patent/JO1604B1/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention concerns novel, pharmaceutically useful 1,3-dioxane alkenoic acid derivatives of the formula I containing a pyridyl moiety at position 4 of the dioxane ring and in which the groups at positions 2, 4 and 5 have cis-relative stereochemistry, X is hydrogen, alkoxy or hydroxy, Y is vinylene, n is 1 or 2, A<1> is alkylene, the substituents R<1> and R<2> at position 2 of the dioxane ring have a variety of values defined hereinafter, and R<4> is hydroxy, a physiologically acceptable alcohol residue or alkanesulphonamido, and the pharmaceutically acceptable salts thereof. The invention also includes processes for the manufacture and use of the acid derivatives as well as pharmaceutical compositions for therapeutic use in one or more of a variety of diseases such as ischaemic heart disease, cerebrovascular disease, asthmatic disease and/or inflammatory disease
JO19891604A 1989-08-18 1989-11-28 Pyridine dervatives JO1604B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898918937A GB8918937D0 (en) 1989-08-18 1989-08-18 Acid derivatives

Publications (1)

Publication Number Publication Date
JO1604B1 true JO1604B1 (en) 1990-07-01

Family

ID=10661864

Family Applications (1)

Application Number Title Priority Date Filing Date
JO19891604A JO1604B1 (en) 1989-08-18 1989-11-28 Pyridine dervatives

Country Status (2)

Country Link
GB (1) GB8918937D0 (en)
JO (1) JO1604B1 (en)

Also Published As

Publication number Publication date
GB8918937D0 (en) 1989-09-27

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