ZA986904B - Process - Google Patents

Process

Info

Publication number
ZA986904B
ZA986904B ZA986904A ZA986904A ZA986904B ZA 986904 B ZA986904 B ZA 986904B ZA 986904 A ZA986904 A ZA 986904A ZA 986904 A ZA986904 A ZA 986904A ZA 986904 B ZA986904 B ZA 986904B
Authority
ZA
South Africa
Prior art keywords
füä1
ethylü
dibenzoäb
hydroxyethoxy
piperazinyl
Prior art date
Application number
ZA986904A
Other languages
English (en)
Inventor
Evan William Snape
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of ZA986904B publication Critical patent/ZA986904B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D281/16—[b, f]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Glass Compositions (AREA)
  • Liquid Crystal Substances (AREA)
ZA986904A 1997-08-01 1998-07-31 Process ZA986904B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9716161.6A GB9716161D0 (en) 1997-08-01 1997-08-01 Process

Publications (1)

Publication Number Publication Date
ZA986904B true ZA986904B (en) 1999-02-01

Family

ID=10816746

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA986904A ZA986904B (en) 1997-08-01 1998-07-31 Process

Country Status (32)

Country Link
US (2) US6372734B1 (de)
EP (2) EP1589008B1 (de)
JP (2) JP2001512109A (de)
KR (1) KR20010022241A (de)
CN (1) CN1125058C (de)
AT (2) ATE496037T1 (de)
AU (1) AU739255B2 (de)
BG (1) BG64796B1 (de)
BR (1) BR9811061A (de)
CA (1) CA2295792C (de)
CY (2) CY2200161T2 (de)
CZ (1) CZ299225B6 (de)
DE (4) DE98936529T1 (de)
EE (1) EE04550B1 (de)
ES (2) ES2296568T3 (de)
GB (2) GB9716161D0 (de)
HK (2) HK1029992A1 (de)
HU (1) HU228620B1 (de)
ID (1) ID24219A (de)
IL (1) IL133618A (de)
MY (1) MY120999A (de)
NO (1) NO20000484L (de)
NZ (1) NZ501914A (de)
PL (1) PL338384A1 (de)
PT (2) PT1000043E (de)
RU (1) RU2224754C2 (de)
SI (2) SI1589008T1 (de)
SK (1) SK287145B6 (de)
TR (1) TR200000848T2 (de)
TW (1) TW533207B (de)
WO (1) WO1999006381A1 (de)
ZA (1) ZA986904B (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030216376A1 (en) * 2002-03-20 2003-11-20 Revital Lifshitz-Liron Crystalline forms of quetiapine hemifumarate
WO2004076431A1 (en) * 2003-02-22 2004-09-10 Teva Pharmaceutical Industries Ltd. Synthesis of quetiapine and pharmaceutically acceptable salts thereof
US7238686B2 (en) * 2003-03-03 2007-07-03 Hetero Drugs Limited Polymorphs of quetiapine fumarate
WO2004089957A1 (en) 2003-04-07 2004-10-21 Hetero Drugs Limited A novel crystalline form of dorzolamide hydrochloride
ES2223294B2 (es) 2003-08-08 2005-10-01 Vita Cientifica, S.L. Procedimiento de preparacion de un compuesto farmaceuticamente activo.
US20060081361A1 (en) * 2004-09-13 2006-04-20 Gabbey Lawrence W Oil cooler with integral filter
WO2006035293A1 (en) * 2004-09-27 2006-04-06 Ranbaxy Laboratories Limited Polymorphic forms of quetiapine hemifumarate
GB0425729D0 (en) * 2004-11-23 2004-12-22 Pliva Res & Dev Ltd Heterocyclic compounds
WO2006056772A2 (en) * 2004-11-23 2006-06-01 Pliva Hrvatska D.O.O. Salts of quetiapine
ES2234447B1 (es) * 2005-03-07 2006-03-01 Union Quimico-Farmaceutica S.A. Procedimiento para la obtencion de un derivado de 11-(4-sustituido-1-piperazinil)dibenzo(b,f)(1,4)tiazepina.
US7687622B2 (en) 2005-04-14 2010-03-30 Teva Pharmaceutical Industries, Ltd Process for preparing quetiapine fumarate
US20070072840A1 (en) * 2005-05-30 2007-03-29 Pandya Bhargav Polymorphic forms of quetiapine
WO2007036599A1 (en) 2005-09-30 2007-04-05 Fermion Oy New crystallization process of quetiapine hemifumarate
US8044039B2 (en) 2005-10-28 2011-10-25 Fermion Oy Quetiapine hemifumarate purification by crystallization
CN101360503A (zh) * 2005-11-18 2009-02-04 阿斯利康公司 液体制剂
EP1951257A4 (de) * 2005-11-18 2008-11-05 Astrazeneca Ab Kristalline formen
US8389510B2 (en) * 2005-11-18 2013-03-05 Astrazeneca Ab Crystalline forms
US20090215744A1 (en) * 2005-11-18 2009-08-27 Astrazeneca Ab Solid Formulations
CN101360724A (zh) * 2005-11-18 2009-02-04 阿斯利康公司 盐形式
CZ300451B6 (cs) * 2006-07-03 2009-05-20 Farmak, A. S. Zpusob prípravy solí 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanolu (quetiapinu) a jejich cištení
WO2008066620A2 (en) * 2006-10-20 2008-06-05 Concert Pharmaceuticals Inc. Dibenzothiazepine derivatives
ATE480227T1 (de) 2007-02-14 2010-09-15 Lesvi Laboratorios Sl Pharmazeutische zusammensetzungen mit quetiapinfumarat
WO2008121415A2 (en) * 2007-03-29 2008-10-09 Teva Pharmaceutical Industries Ltd. Improved process for preparing quetiapine fumarate
US8101597B2 (en) * 2007-05-07 2012-01-24 Actavis Group Ptc Ehf Quetiapine salts and their polymorphs
US20090082334A1 (en) * 2007-09-25 2009-03-26 Protia, Llc Deuterium-enriched quetiapine
ES2535730T3 (es) * 2007-12-05 2015-05-14 Janssen Pharmaceutica, N.V. Agonistas TRPA1 de dibenzoazepinas y dibenzooxazepinas
DK2262486T3 (da) 2008-08-01 2013-03-25 Krka Tovarna Zdravil D D Novo Mesto Quetiapin sammensætning
WO2010033270A1 (en) * 2008-09-17 2010-03-25 Auspex Pharmaceuticals, Inc. Dibenzothiazepine modulators of dopamine, alpha adrenergic, and serotonin receptors
WO2010100623A1 (en) 2009-03-04 2010-09-10 Ranbaxy Laboratories Limited Process for the preparation of quetiapine fumarate
WO2013024072A1 (en) 2011-08-12 2013-02-21 Qiagen Gmbh Method for isolating nucleic acids

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE787249A (fr) 1971-08-05 1973-02-05 Squibb & Sons Inc Derives amino d'acides pyrazolopyridine carboxyliques, leurs esters et les sels de ces composes, ainsi que leurs procedes de preparation
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
GB8705574D0 (en) * 1987-03-10 1987-04-15 Ici Plc Preparation of thiazepine compound

Also Published As

Publication number Publication date
TW533207B (en) 2003-05-21
US6372734B1 (en) 2002-04-16
AU8549898A (en) 1999-02-22
RU2224754C2 (ru) 2004-02-27
ES2296568T1 (es) 2008-05-01
EE200000062A (et) 2000-10-16
WO1999006381A1 (en) 1999-02-11
NZ501914A (en) 2001-09-28
US20020147186A1 (en) 2002-10-10
ID24219A (id) 2000-07-13
SI1000043T1 (sl) 2010-01-29
JP2009102345A (ja) 2009-05-14
PT1000043E (pt) 2009-11-30
SK287145B6 (sk) 2010-01-07
PT1589008E (pt) 2011-03-23
CY2200161T2 (el) 2010-07-28
GB9814882D0 (en) 1998-09-09
ES2296575T3 (es) 2010-02-05
CN1125058C (zh) 2003-10-22
DE98936529T1 (de) 2008-11-20
GB9716161D0 (en) 1997-10-08
ES2296575T1 (es) 2008-05-01
NO20000484D0 (no) 2000-01-31
EP1589008B1 (de) 2011-01-19
MY120999A (en) 2005-12-30
BG64796B1 (bg) 2006-04-28
DE69841216D1 (de) 2009-11-19
KR20010022241A (ko) 2001-03-15
HK1029992A1 (en) 2001-04-20
HUP0002663A3 (en) 2001-10-29
PL338384A1 (en) 2000-10-23
AU739255B2 (en) 2001-10-04
ATE496037T1 (de) 2011-02-15
SK1302000A3 (en) 2000-06-12
CA2295792A1 (en) 1999-02-11
ATE444959T1 (de) 2009-10-15
HU228620B1 (en) 2013-04-29
TR200000848T2 (tr) 2000-08-21
BR9811061A (pt) 2000-09-19
CA2295792C (en) 2007-04-17
CZ299225B6 (cs) 2008-05-21
IL133618A (en) 2004-02-08
IL133618A0 (en) 2001-04-30
EP1000043A1 (de) 2000-05-17
BG104176A (en) 2000-08-31
SI1589008T1 (sl) 2011-04-29
HK1081962A1 (en) 2006-05-26
DE69842104D1 (de) 2011-03-03
JP2001512109A (ja) 2001-08-21
CY2200162T2 (el) 2010-07-28
EE04550B1 (et) 2005-10-17
EP1000043B1 (de) 2009-10-07
DE05011169T1 (de) 2008-11-06
NO20000484L (no) 2000-03-16
CN1265101A (zh) 2000-08-30
HUP0002663A2 (hu) 2001-09-28
EP1589008A1 (de) 2005-10-26
ES2296568T3 (es) 2011-05-06
CZ2000341A3 (cs) 2000-05-17

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