ZA972983B - Process to prepare oxazolidinones - Google Patents

Process to prepare oxazolidinones

Info

Publication number
ZA972983B
ZA972983B ZA972983A ZA972983A ZA972983B ZA 972983 B ZA972983 B ZA 972983B ZA 972983 A ZA972983 A ZA 972983A ZA 972983 A ZA972983 A ZA 972983A ZA 972983 B ZA972983 B ZA 972983B
Authority
ZA
South Africa
Prior art keywords
reacting
substituted
oxazolidinone
oxazolidinones
prepare
Prior art date
Application number
ZA972983A
Other languages
English (en)
Inventor
Bruce A Pearlman
Michale R Barbachyn
Dana S Toops
Thomas J Fleck
William R Perrault
Peter R Manninen
David J Houser
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of ZA972983B publication Critical patent/ZA972983B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18Oxygen atoms
    • C07D263/20Oxygen atoms attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18Oxygen atoms
    • C07D263/20Oxygen atoms attached in position 2
    • C07D263/24Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA972983A 1996-04-11 1997-04-08 Process to prepare oxazolidinones ZA972983B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1549996P 1996-04-11 1996-04-11

Publications (1)

Publication Number Publication Date
ZA972983B true ZA972983B (en) 1998-10-08

Family

ID=21771765

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA972983A ZA972983B (en) 1996-04-11 1997-04-08 Process to prepare oxazolidinones

Country Status (24)

Country Link
US (1) US5837870A (cg-RX-API-DMAC10.html)
EP (2) EP0892792B1 (cg-RX-API-DMAC10.html)
JP (2) JP2000508312A (cg-RX-API-DMAC10.html)
KR (1) KR100530297B1 (cg-RX-API-DMAC10.html)
CN (3) CN1319952C (cg-RX-API-DMAC10.html)
AT (2) ATE209193T1 (cg-RX-API-DMAC10.html)
AU (1) AU706117B2 (cg-RX-API-DMAC10.html)
CA (1) CA2248143C (cg-RX-API-DMAC10.html)
CZ (2) CZ298060B6 (cg-RX-API-DMAC10.html)
DE (2) DE69738457T2 (cg-RX-API-DMAC10.html)
DK (2) DK1114819T3 (cg-RX-API-DMAC10.html)
ES (2) ES2298198T3 (cg-RX-API-DMAC10.html)
HU (1) HUP0500044A3 (cg-RX-API-DMAC10.html)
NO (2) NO311837B1 (cg-RX-API-DMAC10.html)
NZ (1) NZ332278A (cg-RX-API-DMAC10.html)
PL (1) PL192691B1 (cg-RX-API-DMAC10.html)
PT (2) PT892792E (cg-RX-API-DMAC10.html)
RU (1) RU2176643C2 (cg-RX-API-DMAC10.html)
SG (1) SG85683A1 (cg-RX-API-DMAC10.html)
SI (1) SI0892792T1 (cg-RX-API-DMAC10.html)
SK (1) SK284703B6 (cg-RX-API-DMAC10.html)
TW (1) TW449593B (cg-RX-API-DMAC10.html)
WO (1) WO1997037980A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA972983B (cg-RX-API-DMAC10.html)

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GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
ID30299A (id) * 1998-06-05 2001-11-22 Astrazeneca Ab Turunan oksazolidinon, proses pembuatannya dan komposisi farmasi yang mengandungnya
EP1008590B1 (en) * 1998-12-07 2006-10-11 Takasago International Corporation Process for preparing optically active oxazolidinone derivatives
DE60001807T2 (de) 1999-02-01 2003-11-06 Pharmacia & Upjohn Co., Kalamazoo VERFAHREN ZU HERSTELLUNG VON o-FLUORIERTEN TETRAHYDROTHIOPYRAN CARBAMATEN
US6413981B1 (en) 1999-08-12 2002-07-02 Ortho-Mcneil Pharamceutical, Inc. Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
US6608081B2 (en) 1999-08-12 2003-08-19 Ortho-Mcneil Pharmaceutical, Inc. Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
US6297242B1 (en) 1999-08-12 2001-10-02 Ortho-Mcneil Pharmaceutical, Inc. N-substituted amidine and guanidine oxazolidinone antibacterials and methods of use thereof
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
US6518285B2 (en) 1999-12-21 2003-02-11 Ortho Mcneil Pharmaceutical, Inc. Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials
US6444813B2 (en) 2000-02-02 2002-09-03 Pharmacia & Upjohn Company Linezolid-crystal form II
AR027261A1 (es) * 2000-02-02 2003-03-19 Upjohn Co Linezolid forma cristalina ii
MY127336A (en) 2000-03-22 2006-11-30 Upjohn Co Container for linezolid iv solution
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AR031135A1 (es) 2000-10-10 2003-09-10 Upjohn Co Composiciones de antibiotico topico para el tratamiento de infecciones oculares
JP2004531518A (ja) * 2001-04-07 2004-10-14 アストラゼネカ アクチボラグ スルホンイミド基を含有する、抗生物質としてのオキサゾリジノン
AU2002255803B2 (en) 2001-04-20 2008-07-03 Pharmacia And Upjohn Company Process to prepare oxazolidinones
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WO2003106413A2 (en) * 2001-10-18 2003-12-24 Michigan State University Process for the preparation of oxazolidinones and method of use thereof
AU2003213210A1 (en) * 2002-02-22 2003-09-09 Pharmacia Corporation Ophthalmic formulation with gum system
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ES2294494T3 (es) * 2004-04-19 2008-04-01 Symed Labs Limited Un nuevo procedimiento para la preparacion de linezolid y compuestos relacionados.
DE602004020812D1 (de) * 2004-07-20 2009-06-04 Symed Labs Ltd Neue zwischenprodukte für linezolid und verwandte verbindungen
RU2008139612A (ru) * 2006-04-07 2010-04-20 Пфайзер Продактс Инк. (Us) Способ получения линезолида
CN100395270C (zh) * 2006-05-25 2008-06-18 湖北大学 线型聚苯乙烯支载的(4s)-5,5-二取代基噁唑烷酮及其制备方法和用途
EP2033960A3 (en) * 2007-09-04 2009-04-29 Dipharma Francis S.r.l. Linezolid crystalline hydrate form and linezolid salts
WO2009032294A2 (en) * 2007-09-06 2009-03-12 Teva Pharmaceutical Industries Ltd. Processes for the preparation of a linezolid intermediate, linezolid hydroxide
EP2163547A1 (en) 2008-09-16 2010-03-17 Unión Químico Farmacéutica, S.A. (UQUIFA) Process for the preparation of an oxazolidinone antibacterial agent and intermediates thereof
JP5561462B2 (ja) * 2009-09-17 2014-07-30 日東化成株式会社 漁網防汚塗料組成物、該組成物を用いて形成される防汚塗膜、該塗膜の形成方法、および該塗膜を表面に有する漁網、漁網用具又は水中構造物
US20130137864A1 (en) 2009-12-26 2013-05-30 Jayaraman Venkat Raman Process for the preparation of linezolid
WO2011080341A1 (en) 2010-01-04 2011-07-07 Enantia, S.L. Process for the preparation of rivaroxaban and intermediates thereof
WO2012019632A1 (en) 2010-08-11 2012-02-16 Synthon B.V. Process for making linezolid
EP2690100A1 (en) 2010-08-11 2014-01-29 Synhton B.V. Process for making linezolid
EP2635589A1 (en) 2010-11-03 2013-09-11 Wockhardt Limited Process for the preparation of phosphoric acid mono- (l-{4- [(s) -5- (acetylaminomethyl) - 2 - oxo - oxazolidin- 3 - yl]- 2, 6 - difluorophenyl} - 4 -methoxymethylpiperidin- 4 - yl) ester
US9567307B2 (en) * 2011-01-07 2017-02-14 The Regents Of The University Of California Amination of aryl alcohol derivatives
CN102153521B (zh) * 2011-01-31 2012-09-12 宁波市鄞州百特佳医药科技有限公司 一种用于制备利奈唑胺的中间体及其制备方法
US20140114065A1 (en) 2011-02-24 2014-04-24 Lee Phama Limited Anhydrous linezolid crystalline form-ii
WO2012114355A1 (en) * 2011-02-24 2012-08-30 Lee Pharma Limited Novel process for preparation of linezolid and its novel intermediates
CN102311402B (zh) * 2011-07-18 2013-08-21 苏州敬业医药化工有限公司 3-取代苯基-5-羟甲基噁唑烷-2-酮的制备方法
CN102321042B (zh) * 2011-07-18 2013-12-04 苏州敬业医药化工有限公司 3-取代苯基-5-羟甲基噁唑烷-2-酮的制备方法
WO2013072923A1 (en) 2011-09-19 2013-05-23 Cadila Healthcare Limited Process for the preparation of crystalline linezolid
WO2013111048A1 (en) 2012-01-24 2013-08-01 Jubilant Life Sciences Limited Improved process for the preparation of stable crystalline form-i of linezolid, substantially free of residual solvent
CN103626712B (zh) * 2012-08-23 2016-06-01 重庆药友制药有限责任公司 一种用于制备利奈唑胺的中间体及其制备方法
ES2603252T3 (es) 2012-11-09 2017-02-24 Synthon Bv Proceso para preparar linezolid
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Also Published As

Publication number Publication date
CN1319952C (zh) 2007-06-06
SK133698A3 (en) 1999-06-11
CA2248143A1 (en) 1997-10-16
AU706117B2 (en) 1999-06-10
EP1114819A1 (en) 2001-07-11
HU0500044D0 (en) 2005-03-29
NZ332278A (en) 2000-05-26
HK1018785A1 (en) 2000-01-07
DE69709718D1 (de) 2002-02-21
SG85683A1 (en) 2002-01-15
EP0892792B1 (en) 2001-11-21
KR100530297B1 (ko) 2005-11-22
SI0892792T1 (en) 2002-06-30
DE69738457D1 (de) 2008-02-21
DE69738457T2 (de) 2008-12-24
US5837870A (en) 1998-11-17
AU2318297A (en) 1997-10-29
DE69709718T2 (de) 2002-06-20
JP2000508312A (ja) 2000-07-04
PT1114819E (pt) 2008-02-28
PL329295A1 (en) 1999-03-15
JP2008239621A (ja) 2008-10-09
CZ200788A3 (cs) 2017-01-25
ATE383347T1 (de) 2008-01-15
HK1061241A1 (en) 2004-09-10
DK0892792T3 (da) 2002-04-02
NO984737D0 (no) 1998-10-09
PT892792E (pt) 2002-05-31
PL192691B1 (pl) 2006-11-30
NO984737L (no) 1998-12-09
NO312728B1 (no) 2002-06-24
EP1114819B1 (en) 2008-01-09
CN1381454A (zh) 2002-11-27
NO311837B1 (no) 2002-02-04
CA2248143C (en) 2008-10-07
DK1114819T3 (da) 2008-04-14
KR20040066189A (ko) 2004-07-23
HUP0500044A3 (en) 2005-09-28
NO20015253L (no) 1998-12-09
WO1997037980A1 (en) 1997-10-16
CN1167701C (zh) 2004-09-22
ES2166073T3 (es) 2002-04-01
CN1215393A (zh) 1999-04-28
SK284703B6 (sk) 2005-09-08
CN1496983A (zh) 2004-05-19
EP0892792A1 (en) 1999-01-27
CZ287198A3 (cs) 1999-02-17
RU2176643C2 (ru) 2001-12-10
ATE209193T1 (de) 2001-12-15
CZ298060B6 (cs) 2007-06-06
ES2298198T3 (es) 2008-05-16
TW449593B (en) 2001-08-11
NO20015253D0 (no) 2001-10-26
CN1082953C (zh) 2002-04-17

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