HUP0500044A3 - Process for prepare oxazolidinones - Google Patents

Process for prepare oxazolidinones

Info

Publication number
HUP0500044A3
HUP0500044A3 HU0500044A HUP0500044A HUP0500044A3 HU P0500044 A3 HUP0500044 A3 HU P0500044A3 HU 0500044 A HU0500044 A HU 0500044A HU P0500044 A HUP0500044 A HU P0500044A HU P0500044 A3 HUP0500044 A3 HU P0500044A3
Authority
HU
Hungary
Prior art keywords
oxazolidinones
prepare
prepare oxazolidinones
Prior art date
Application number
HU0500044A
Other languages
English (en)
Hungarian (hu)
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of HU0500044D0 publication Critical patent/HU0500044D0/hu
Publication of HUP0500044A3 publication Critical patent/HUP0500044A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU0500044A 1996-04-11 1997-03-28 Process for prepare oxazolidinones HUP0500044A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1549996P 1996-04-11 1996-04-11
PCT/US1997/003458 WO1997037980A1 (en) 1996-04-11 1997-03-28 Process to prepare oxazolidinones

Publications (2)

Publication Number Publication Date
HU0500044D0 HU0500044D0 (en) 2005-03-29
HUP0500044A3 true HUP0500044A3 (en) 2005-09-28

Family

ID=21771765

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0500044A HUP0500044A3 (en) 1996-04-11 1997-03-28 Process for prepare oxazolidinones

Country Status (24)

Country Link
US (1) US5837870A (cg-RX-API-DMAC10.html)
EP (2) EP0892792B1 (cg-RX-API-DMAC10.html)
JP (2) JP2000508312A (cg-RX-API-DMAC10.html)
KR (1) KR100530297B1 (cg-RX-API-DMAC10.html)
CN (3) CN1167701C (cg-RX-API-DMAC10.html)
AT (2) ATE383347T1 (cg-RX-API-DMAC10.html)
AU (1) AU706117B2 (cg-RX-API-DMAC10.html)
CA (1) CA2248143C (cg-RX-API-DMAC10.html)
CZ (2) CZ298060B6 (cg-RX-API-DMAC10.html)
DE (2) DE69738457T2 (cg-RX-API-DMAC10.html)
DK (2) DK0892792T3 (cg-RX-API-DMAC10.html)
ES (2) ES2166073T3 (cg-RX-API-DMAC10.html)
HU (1) HUP0500044A3 (cg-RX-API-DMAC10.html)
NO (2) NO311837B1 (cg-RX-API-DMAC10.html)
NZ (1) NZ332278A (cg-RX-API-DMAC10.html)
PL (1) PL192691B1 (cg-RX-API-DMAC10.html)
PT (2) PT892792E (cg-RX-API-DMAC10.html)
RU (1) RU2176643C2 (cg-RX-API-DMAC10.html)
SG (1) SG85683A1 (cg-RX-API-DMAC10.html)
SI (1) SI0892792T1 (cg-RX-API-DMAC10.html)
SK (1) SK284703B6 (cg-RX-API-DMAC10.html)
TW (1) TW449593B (cg-RX-API-DMAC10.html)
WO (1) WO1997037980A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA972983B (cg-RX-API-DMAC10.html)

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GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
AU753988B2 (en) 1998-06-05 2002-10-31 Astrazeneca Ab Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
DE69933526D1 (de) * 1998-12-07 2006-11-23 Takasago Perfumery Co Ltd Verfahren zur Herstellung von optisch aktiven Oxazolidinonderivate
ATE293616T1 (de) 1999-02-01 2005-05-15 Upjohn Co 2-fluoro-(oxido-thiopyran-4-yl)benzol derivate
US6608081B2 (en) 1999-08-12 2003-08-19 Ortho-Mcneil Pharmaceutical, Inc. Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
US6297242B1 (en) 1999-08-12 2001-10-02 Ortho-Mcneil Pharmaceutical, Inc. N-substituted amidine and guanidine oxazolidinone antibacterials and methods of use thereof
US6413981B1 (en) 1999-08-12 2002-07-02 Ortho-Mcneil Pharamceutical, Inc. Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
US6518285B2 (en) 1999-12-21 2003-02-11 Ortho Mcneil Pharmaceutical, Inc. Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials
US6444813B2 (en) 2000-02-02 2002-09-03 Pharmacia & Upjohn Company Linezolid-crystal form II
AR027261A1 (es) * 2000-02-02 2003-03-19 Upjohn Co Linezolid forma cristalina ii
US6514529B2 (en) 2000-03-22 2003-02-04 Pharmacia & Upjohn Company Oxazolidinone tablet formulation
MY127336A (en) * 2000-03-22 2006-11-30 Upjohn Co Container for linezolid iv solution
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
ES2245698T3 (es) 2000-06-30 2006-01-16 PHARMACIA & UPJOHN COMPANY LLC Composiciones para el tratamiento de infecciones bacterianas que contienen un compuesto de oxazolidinona, sulbactam y ampicilina.
PE20020300A1 (es) * 2000-08-22 2002-05-10 Pharmacia Corp Composicion de solucion de un farmaco antibiotico a base de oxazolidinona con mejoramiento de la carga de farmaco
US6288239B1 (en) 2000-09-19 2001-09-11 Board Of Trustees Operating Michigan State University 5-trityloxymethyl-oxazolidinones and process for the preparation thereof
PE20020578A1 (es) 2000-10-10 2002-08-14 Upjohn Co Una composicion de antibiotico topico para el tratamiento de infecciones oculares
JP2004531518A (ja) * 2001-04-07 2004-10-14 アストラゼネカ アクチボラグ スルホンイミド基を含有する、抗生物質としてのオキサゾリジノン
ES2291465T3 (es) * 2001-04-20 2008-03-01 PHARMACIA & UPJOHN COMPANY LLC Procedimiento para preparar oxazolidinonas.
ES2186550B2 (es) * 2001-06-27 2003-11-16 Vita Lab Nuevos derivados de oxazolidinonas como antibacterianos.
JP2005519996A (ja) * 2001-10-18 2005-07-07 ミシガン ステイト ユニバーシティー オキサゾリジノン類の製造方法及びその使用方法
JP2005521691A (ja) * 2002-02-22 2005-07-21 ファルマシア・コーポレーション シクロデキストリン化合物及び塩化セチルピリジニウムを含有する眼科用抗菌性薬物製剤
EP1476135A1 (en) * 2002-02-22 2004-11-17 Pharmacia Corporation Ophthalmic formulation with gum system
EP2902386B1 (en) * 2003-10-16 2020-04-08 Symed Labs Limited A crystalline form of linezolid
US7307163B2 (en) * 2004-04-19 2007-12-11 Symed Labs Limited Process for the preparation of linezolid and related compounds
DE602004020812D1 (de) * 2004-07-20 2009-06-04 Symed Labs Ltd Neue zwischenprodukte für linezolid und verwandte verbindungen
MX2008012941A (es) * 2006-04-07 2008-10-15 Pfizer Prod Inc Un procedimiento novedoso para preparar agentes antibacterianos de oxazolidinona.
CN100395270C (zh) * 2006-05-25 2008-06-18 湖北大学 线型聚苯乙烯支载的(4s)-5,5-二取代基噁唑烷酮及其制备方法和用途
EP2033960A3 (en) * 2007-09-04 2009-04-29 Dipharma Francis S.r.l. Linezolid crystalline hydrate form and linezolid salts
US20090093631A1 (en) * 2007-09-06 2009-04-09 Ben-Zion Dolitzky Processes for the preparation of a linezolid intermediate, linezolid hydroxide
EP2163547A1 (en) 2008-09-16 2010-03-17 Unión Químico Farmacéutica, S.A. (UQUIFA) Process for the preparation of an oxazolidinone antibacterial agent and intermediates thereof
JP5561462B2 (ja) * 2009-09-17 2014-07-30 日東化成株式会社 漁網防汚塗料組成物、該組成物を用いて形成される防汚塗膜、該塗膜の形成方法、および該塗膜を表面に有する漁網、漁網用具又は水中構造物
EP2516408A1 (en) * 2009-12-26 2012-10-31 Alembic Pharmaceuticals Limited Process for the preparation of linezolid
EP2521723A1 (en) 2010-01-04 2012-11-14 Enantia, S.L. Process for the preparation of rivaroxaban and intermediates thereof
EP2603505A1 (en) 2010-08-11 2013-06-19 Synthon BV Process for making linezolid
EP2690100A1 (en) 2010-08-11 2014-01-29 Synhton B.V. Process for making linezolid
KR20130102614A (ko) 2010-11-03 2013-09-17 욱크하르트 리미티드 인산 모노-(1-[4-[(s)-5-(아세틸아미노메틸)-2-옥소-옥사졸리딘-3-일]-2,6-디플루오로페닐]-4-메톡시메틸피페리딘-4-일) 에스테르의 제조 방법
WO2012094622A2 (en) * 2011-01-07 2012-07-12 The Regents Of The University Of California Amination of aryl alcohol derivatives
CN102153521B (zh) * 2011-01-31 2012-09-12 宁波市鄞州百特佳医药科技有限公司 一种用于制备利奈唑胺的中间体及其制备方法
EP2593440A1 (en) 2011-02-24 2013-05-22 Lee Pharma Limited Anhydrous linezolid crystalline form-ii
CN106279054A (zh) 2011-02-24 2017-01-04 李药业有限公司 利奈唑胺及其新中间体的新制备方法
CN102311402B (zh) * 2011-07-18 2013-08-21 苏州敬业医药化工有限公司 3-取代苯基-5-羟甲基噁唑烷-2-酮的制备方法
CN102321042B (zh) * 2011-07-18 2013-12-04 苏州敬业医药化工有限公司 3-取代苯基-5-羟甲基噁唑烷-2-酮的制备方法
WO2013072923A1 (en) 2011-09-19 2013-05-23 Cadila Healthcare Limited Process for the preparation of crystalline linezolid
EP2852580A1 (en) 2012-01-24 2015-04-01 Jubilant Life Sciences Ltd. Improved process for the preparation of stable crystalline form-i of linezolid, substantially free of residual solvent
CN103626712B (zh) * 2012-08-23 2016-06-01 重庆药友制药有限责任公司 一种用于制备利奈唑胺的中间体及其制备方法
EP2917189B1 (en) 2012-11-09 2016-08-17 Synthon BV Process for making linezolid
WO2015173664A1 (en) 2014-05-14 2015-11-19 Wockhardt Limited Process for the preparation of (5s)-n-{3-[3,5-difluoro-4-(4-hydroxy-4-methoxymethyl-piperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide
WO2021184339A1 (en) 2020-03-20 2021-09-23 Merck Sharp & Dohme Corp. Oxazolidinone compound and methods of use thereof as an antibacterial agent
CN119119019B (zh) * 2024-09-11 2025-11-11 遵义医科大学 一种杂环磺酰胺/磺酸酯衍生物及其制备方法、应用

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Also Published As

Publication number Publication date
PT1114819E (pt) 2008-02-28
EP0892792A1 (en) 1999-01-27
SK284703B6 (sk) 2005-09-08
JP2008239621A (ja) 2008-10-09
HK1061241A1 (en) 2004-09-10
ZA972983B (en) 1998-10-08
EP1114819B1 (en) 2008-01-09
ATE383347T1 (de) 2008-01-15
TW449593B (en) 2001-08-11
SG85683A1 (en) 2002-01-15
PL192691B1 (pl) 2006-11-30
ES2166073T3 (es) 2002-04-01
NO311837B1 (no) 2002-02-04
CZ200788A3 (cs) 2017-01-25
CN1496983A (zh) 2004-05-19
DK1114819T3 (da) 2008-04-14
AU706117B2 (en) 1999-06-10
NO20015253L (no) 1998-12-09
NO20015253D0 (no) 2001-10-26
CN1215393A (zh) 1999-04-28
NO984737L (no) 1998-12-09
KR20040066189A (ko) 2004-07-23
SI0892792T1 (en) 2002-06-30
AU2318297A (en) 1997-10-29
DE69709718D1 (de) 2002-02-21
CN1381454A (zh) 2002-11-27
DE69709718T2 (de) 2002-06-20
NO312728B1 (no) 2002-06-24
EP1114819A1 (en) 2001-07-11
CZ298060B6 (cs) 2007-06-06
US5837870A (en) 1998-11-17
EP0892792B1 (en) 2001-11-21
WO1997037980A1 (en) 1997-10-16
KR100530297B1 (ko) 2005-11-22
ATE209193T1 (de) 2001-12-15
CN1167701C (zh) 2004-09-22
CA2248143A1 (en) 1997-10-16
DE69738457T2 (de) 2008-12-24
CN1082953C (zh) 2002-04-17
DE69738457D1 (de) 2008-02-21
RU2176643C2 (ru) 2001-12-10
CA2248143C (en) 2008-10-07
NZ332278A (en) 2000-05-26
HU0500044D0 (en) 2005-03-29
HK1018785A1 (en) 2000-01-07
ES2298198T3 (es) 2008-05-16
PL329295A1 (en) 1999-03-15
DK0892792T3 (da) 2002-04-02
SK133698A3 (en) 1999-06-11
JP2000508312A (ja) 2000-07-04
CZ287198A3 (cs) 1999-02-17
PT892792E (pt) 2002-05-31
NO984737D0 (no) 1998-10-09
CN1319952C (zh) 2007-06-06

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