ZA92233B - Novel steroids - Google Patents

Novel steroids

Info

Publication number
ZA92233B
ZA92233B ZA92233A ZA92233A ZA92233B ZA 92233 B ZA92233 B ZA 92233B ZA 92233 A ZA92233 A ZA 92233A ZA 92233 A ZA92233 A ZA 92233A ZA 92233 B ZA92233 B ZA 92233B
Authority
ZA
South Africa
Prior art keywords
novel steroids
steroids
novel
Prior art date
Application number
ZA92233A
Other languages
English (en)
Inventor
Paul Haekan Andersson
Bengt Ingemar Axelsson
Ralph Lennart Brattsand
Arne Bror Thalen
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of ZA92233B publication Critical patent/ZA92233B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0092—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by an OH group free esterified or etherified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ZA92233A 1991-02-04 1992-01-13 Novel steroids ZA92233B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9100341A SE9100341D0 (sv) 1991-02-04 1991-02-04 Novel steroids

Publications (1)

Publication Number Publication Date
ZA92233B true ZA92233B (en) 1992-10-28

Family

ID=20381806

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA92233A ZA92233B (en) 1991-02-04 1992-01-13 Novel steroids

Country Status (40)

Country Link
US (2) US5674861A (ru)
EP (1) EP0570454B1 (ru)
JP (1) JPH06505232A (ru)
KR (1) KR100216720B1 (ru)
CN (3) CN1034868C (ru)
AP (1) AP366A (ru)
AT (1) ATE178611T1 (ru)
BG (1) BG62211B1 (ru)
CA (1) CA2103924A1 (ru)
CZ (1) CZ281685B6 (ru)
DE (1) DE69228870T2 (ru)
DK (1) DK0570454T3 (ru)
DZ (1) DZ1553A1 (ru)
EE (1) EE03111B1 (ru)
ES (1) ES2133315T3 (ru)
FI (1) FI933450A0 (ru)
GR (1) GR3030657T3 (ru)
HK (1) HK1010733A1 (ru)
HU (1) HU218275B (ru)
IE (1) IE920166A1 (ru)
IL (1) IL100532A (ru)
IS (1) IS1601B (ru)
MA (1) MA22406A1 (ru)
MX (1) MX9200324A (ru)
NO (1) NO304073B1 (ru)
NZ (1) NZ241210A (ru)
PH (1) PH31284A (ru)
PL (1) PL170000B1 (ru)
PT (1) PT100086B (ru)
RO (1) RO111195B1 (ru)
RU (1) RU2111212C1 (ru)
SE (1) SE9100341D0 (ru)
SG (1) SG52557A1 (ru)
SI (1) SI9210065B (ru)
SK (1) SK281801B6 (ru)
TN (1) TNSN92007A1 (ru)
UA (1) UA41267C2 (ru)
WO (1) WO1992013872A1 (ru)
YU (1) YU48892B (ru)
ZA (1) ZA92233B (ru)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9100341D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroids
KR960700266A (ko) * 1993-01-08 1996-01-19 클래스 빌헬름슨 신규 결장- 또는 회장-특이성 스테로이드 유도체(Novel Colon-or lleum-Specific Steroid Derivatives)
US5983956A (en) 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
US5980949A (en) * 1994-10-03 1999-11-09 Astra Aktiebolag Formulation for inhalation
GB9423919D0 (en) * 1994-11-26 1995-01-11 Rhone Poulenc Rorer Ltd Chemical process
SE9700135D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
IT1291288B1 (it) 1997-04-30 1999-01-07 Farmabios Srl Processo per la preparazione di 16,17 acetali di derivati pregnanici con controllo della distribuzione epimerica al c-22.
CA2330611A1 (en) 1998-05-22 1999-12-02 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
GB0009607D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Medical compositions
GB0009592D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Respiratory combinations
HRP20010018A2 (en) 2001-01-09 2002-12-31 Pliva D D Novel anti-inflammatory compounds
GB0110411D0 (en) * 2001-04-27 2001-06-20 Astrazeneca Ab Chemical process
JP2005505578A (ja) * 2001-09-25 2005-02-24 ファルマシア アンド アップジョン カンパニー リミティド ライアビリティー カンパニー ステロイドｃ−２２位アセトニドの立体選択的トランスアセタール化
NZ537717A (en) 2002-07-08 2006-04-28 Pliva Istrazivacki Inst D New compounds, compositions and methods for treatment of inflammatory diseases and conditions
PL375162A1 (en) 2002-07-08 2005-11-28 Pliva-Istrazivacki Institut D.O.O. Novel compounds, compositions as carriers for steroid/non-steroid anti-inflammatory, antineoplastic and antiviral active molecules
US20040157810A1 (en) * 2002-08-23 2004-08-12 Teicher Martin H. Corticosteroid conjugates and uses thereof
TW200417371A (en) * 2003-02-21 2004-09-16 Upjohn Co A continuous process for the production of R-rofleponide
HRP20030324A2 (en) 2003-04-24 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. Compounds of antiinflammatory effect
HRP20030604A2 (en) 2003-07-25 2005-04-30 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromenes, preparation thereof andtheir antiinflammatory action
HRP20030603A2 (en) 2003-07-25 2005-10-31 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromene compounds of antiinflammatory action
ES2337915T3 (es) 2004-10-27 2010-04-30 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Conjugados con adtividad antiinflamatoria.
EP2671508B1 (en) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-informatics system
WO2007008155A1 (en) * 2005-07-11 2007-01-18 Astrazeneca Ab New combination 1
JP2009508494A (ja) 2005-09-16 2009-03-05 ラプトール ファーマシューティカル インコーポレイテッド Ｃｒを含むタンパク質に対して特異的な受容体−結合タンパク質（ｒａｐ）変異体を含む組成物およびその使用
US20080200441A1 (en) * 2007-02-14 2008-08-21 University Of Southern California Estrogen receptor modulators associated pharmaceutical compositions and methods of use
HUE059078T2 (hu) 2009-02-20 2022-10-28 Enhanx Biopharm Inc Glutation-alapú hatóanyagszállító rendszer
JP2012526144A (ja) 2009-05-06 2012-10-25 ラボラトリー スキン ケア インコーポレイテッド 活性物質−リン酸カルシウム粒子複合体を含む経皮送達組成物およびその使用方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126375A (en) * 1964-03-24 Chioacyl
US3048581A (en) * 1960-04-25 1962-08-07 Olin Mathieson Acetals and ketals of 16, 17-dihydroxy steroids
US3357974A (en) * 1965-12-28 1967-12-12 Merck & Co Inc Processes for preparing 16alpha, 17alpha-acetals and ketals of 16alpha, 17alpha, 21-trihydroxy-delta4-pregnene-3, 20-diones
US3758686A (en) * 1971-12-07 1973-09-11 American Cyanamid Co Method of using steroid acetonides
SE378109B (ru) * 1972-05-19 1975-08-18 Bofors Ab
SE378110B (ru) * 1972-05-19 1975-08-18 Bofors Ab
SE8008524L (sv) * 1980-12-04 1982-06-05 Draco Ab 4-pregnen-derivat, ett forfarande for deras framstellning, beredning och metod for behandling av inflammatoriska tillstand
US4749649A (en) * 1983-05-16 1988-06-07 The Upjohn Company Microbial Δ1-dehydrogenation process using a scavenger of toxic oxygen
IT1196142B (it) * 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti
SE8403905D0 (sv) * 1984-07-30 1984-07-30 Draco Ab Liposomes and steroid esters
CN1060471A (zh) * 1985-04-04 1992-04-22 得拉科公司 新的16，17-缩醛取代雄甾烷-17β-酮类的制备方法
SE8604059D0 (sv) * 1986-09-25 1986-09-25 Astra Pharma Prod A method of controlling the epimeric distribution in the preparation of 16,17-acetals of pregnane derivatives
HU203562B (en) * 1989-03-09 1991-08-28 Richter Gedeon Vegyeszet Process for producing new steroide diols and pharmaceutical compositions containing them
HU203769B (en) * 1989-03-09 1991-09-30 Richter Gedeon Vegyeszet Process for producing new steroide derivatives and pharmaceutical compositions containing them
PL164294B1 (pl) * 1990-12-20 1994-07-29 Inst Farmaceutyczny Sposób otrzymywania diastereoizomeru /22R/-16a , 17a-butylidenodioksy-11 ß 21-dihydroksy-1,4-pregnadien-3,20-dionu PL
SE9100342D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroid esters
SE9100341D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroids

Also Published As

Publication number Publication date
AU1230792A (en) 1992-09-07
DE69228870T2 (de) 1999-08-19
NO304073B1 (no) 1998-10-19
MA22406A1 (fr) 1992-10-01
SG52557A1 (en) 1998-09-28
WO1992013872A1 (en) 1992-08-20
CZ281685B6 (cs) 1996-12-11
TNSN92007A1 (fr) 1993-06-08
HU218275B (en) 2000-07-28
CN1140178A (zh) 1997-01-15
FI933450A (fi) 1993-08-03
DK0570454T3 (da) 1999-10-18
RO111195B1 (ro) 1996-07-30
US5939409A (en) 1999-08-17
SK79693A3 (en) 1994-03-09
UA41267C2 (uk) 2001-09-17
AP9200353A0 (en) 1992-01-31
CA2103924A1 (en) 1992-08-05
PT100086B (pt) 1999-06-30
CN1140059A (zh) 1997-01-15
MX9200324A (es) 1992-09-01
SI9210065A (en) 1995-02-28
IE920166A1 (en) 1992-08-12
JPH06505232A (ja) 1994-06-16
YU48892B (sh) 2002-10-18
DE69228870D1 (de) 1999-05-12
BG62211B1 (bg) 1999-05-31
NO932761D0 (no) 1993-08-02
YU6592A (sh) 1995-01-31
CN1052155C (zh) 2000-05-10
HK1010733A1 (en) 1999-06-25
FI933450A0 (fi) 1993-08-03
BG97971A (bg) 1994-04-29
ATE178611T1 (de) 1999-04-15
DZ1553A1 (fr) 2002-02-17
SI9210065B (en) 2001-12-31
EE03111B1 (et) 1998-08-17
PT100086A (pt) 1994-05-31
ES2133315T3 (es) 1999-09-16
NZ241210A (en) 1993-08-26
HU9302244D0 (en) 1993-10-28
IL100532A (en) 1996-05-14
CN1058724C (zh) 2000-11-22
SE9100341D0 (sv) 1991-02-04
EP0570454A1 (en) 1993-11-24
IS1601B (is) 1996-10-18
RU2111212C1 (ru) 1998-05-20
PH31284A (en) 1998-07-06
IS3808A (is) 1992-08-05
KR100216720B1 (ko) 1999-10-01
CN1064079A (zh) 1992-09-02
US5674861A (en) 1997-10-07
AU661471B2 (en) 1995-07-27
PL170000B1 (pl) 1996-10-31
EP0570454B1 (en) 1999-04-07
IL100532A0 (en) 1992-09-06
NO932761L (no) 1993-08-02
HUT64973A (en) 1994-03-28
GR3030657T3 (en) 1999-10-29
CZ149693A3 (en) 1994-03-16
CN1034868C (zh) 1997-05-14
AP366A (en) 1994-10-21
SK281801B6 (sk) 2001-08-06

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