ZA905615B - Sucrose-6-ester chlorination - Google Patents

Sucrose-6-ester chlorination

Info

Publication number
ZA905615B
ZA905615B ZA905615A ZA905615A ZA905615B ZA 905615 B ZA905615 B ZA 905615B ZA 905615 A ZA905615 A ZA 905615A ZA 905615 A ZA905615 A ZA 905615A ZA 905615 B ZA905615 B ZA 905615B
Authority
ZA
South Africa
Prior art keywords
sucrose
ester chlorination
chlorination
ester
Prior art date
Application number
ZA905615A
Other languages
English (en)
Inventor
Robert E Walkup
E Walkup Robert
Juan L Navia
L Navia Juan
Nicholas M Vernon
M Vernon Nicholas
Original Assignee
Noramco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23507711&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA905615(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Noramco Inc filed Critical Noramco Inc
Publication of ZA905615B publication Critical patent/ZA905615B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
ZA905615A 1989-07-18 1990-07-17 Sucrose-6-ester chlorination ZA905615B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/382,147 US4980463A (en) 1989-07-18 1989-07-18 Sucrose-6-ester chlorination

Publications (1)

Publication Number Publication Date
ZA905615B true ZA905615B (en) 1992-03-25

Family

ID=23507711

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA905615A ZA905615B (en) 1989-07-18 1990-07-17 Sucrose-6-ester chlorination

Country Status (26)

Country Link
US (1) US4980463A (fr)
EP (1) EP0409549B1 (fr)
JP (1) JP3183506B2 (fr)
KR (1) KR0144344B1 (fr)
AR (1) AR247401A1 (fr)
AT (1) ATE133175T1 (fr)
AU (1) AU625908B2 (fr)
CA (1) CA2021632C (fr)
DE (1) DE69024868T2 (fr)
DK (1) DK0409549T3 (fr)
ES (1) ES2088973T3 (fr)
FI (1) FI95802C (fr)
GR (1) GR1002037B (fr)
IE (1) IE69961B1 (fr)
IL (1) IL94994A (fr)
MX (1) MX164442B (fr)
NO (1) NO175532C (fr)
NZ (1) NZ234468A (fr)
PE (1) PE21591A1 (fr)
PH (1) PH26799A (fr)
PT (1) PT94719B (fr)
RU (1) RU1836377C (fr)
TR (1) TR28705A (fr)
TW (1) TW219939B (fr)
YU (1) YU47948B (fr)
ZA (1) ZA905615B (fr)

Families Citing this family (89)

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WO1996001832A1 (fr) 1994-07-11 1996-01-25 The United States Of America, Represented By The Secretary Of The Department Of Agriculture Esters de sucre obtenus par synthese chimique pour la lutte contre les arthropodes a corps mou
US6608039B1 (en) 1994-07-11 2003-08-19 The United States Of America As Represented By The Secretary Of Agriculture Chemically synthesized sugar esters for the control of soft-bodied arthropods
US5498709A (en) * 1994-10-17 1996-03-12 Mcneil-Ppc, Inc. Production of sucralose without intermediate isolation of crystalline sucralose-6-ester
KR100405203B1 (ko) * 1996-05-23 2004-02-14 비앤티엔지니어링(주) 암거배수로관
ES2231964T3 (es) * 1997-02-13 2005-05-16 TATE & LYLE PUBLIC LIMITED COMPANY Purificacion cromatografica de sucrosa clorada.
RU2217435C2 (ru) * 1998-05-15 2003-11-27 Ростислав Георгиевич Жбанков Способ получения 4,1'6'-трихлор-4,1',6'-тридезоксигалактосахарозы
DE19924770A1 (de) * 1999-05-29 2000-12-21 Buna Sow Leuna Olefinverb Gmbh Verfahren zur Herstellung von Polyetherpolyolen aus Polysacchariden und deren Verwendung für die Herstellung von PUR-Schäumen
US6500973B2 (en) 2000-06-02 2002-12-31 Eastman Chemical Company Extractive solution crystallization of chemical compounds
DE60133011T2 (de) * 2000-08-25 2009-03-19 Eastman Chemical Co., Kingsport Verfahren zur herstellung von disaccharid und trisaccharid c6-c12 fettsäure-estern mit hohem alpha gehalt und materialien davon
US6667397B2 (en) * 2000-08-25 2003-12-23 Eastman Chemical Company Methods of preparing disaccharide and trisaccharide C6-C12 fatty acid esters with high alpha content and materials therefrom
JP4560637B2 (ja) 2000-11-17 2010-10-13 テート アンド ライル テクノロジー リミテッド 改良されたスクラロース組成物およびその結晶化の方法
US7049435B2 (en) 2002-03-08 2006-05-23 Tate & Lyle Public Limited Company Extractive methods for purifying sucralose
US6998480B2 (en) * 2002-03-08 2006-02-14 Tate & Lyle Public Limited Company Process for improving sucralose purity and yield
US20040170735A2 (en) * 2002-04-05 2004-09-02 Mcneil-Ppc, Inc. Methods and compositions for altering the sweetness delivery profile of sucralose
US6890581B2 (en) * 2002-04-05 2005-05-10 Tate & Lyle Public Limited Company Methods for buffer stabilized aqueous deacylation
US20040086605A1 (en) * 2002-10-30 2004-05-06 Sox Thomas E. Composition for delivering a high intensity sweetener
US6943248B2 (en) 2003-04-30 2005-09-13 Tate & Lyle Public Limited Company Crystalline form of sucralose, and method for producing it
CN1176094C (zh) * 2003-05-23 2004-11-17 广东省食品工业研究所 一种三氯蔗糖的合成方法
CA2558683A1 (fr) * 2004-03-05 2005-09-22 Sunil Srivastava Compositions edulcorantes puissantes a base de polyol
EP1735327B1 (fr) * 2004-03-19 2011-05-04 V.B. Medicare Pvt. Ltd. Procede ameliore pour la production de saccharose chlore
US20050214425A1 (en) * 2004-03-23 2005-09-29 Roma Vazirani Sugar substitute prepared with nutritive and high-intensity sweeteners
GB2437205B (en) * 2004-12-10 2010-03-17 Pharmed Medicare Pvt Ltd Control of ph by direct addition of carbonates and bicarbonates during concentration of organic solvent extracts of 6-acetyl-4,1',6'trichlorogalactosucrose
WO2006061855A2 (fr) * 2004-12-10 2006-06-15 Pharmed Medicare Private Limited Extraction selective a l'aide de sels de 6-acetyl-4, 1', 6' trichlorogalactosucrose et 4, 1', 6' trichlorogalactosucrose a partir d'un melange de reaction aqueux
CN101098972A (zh) * 2004-12-10 2008-01-02 法马德医疗保险私人有限公司 硅烷化硅胶色谱纯化6-乙酰基-4,1',6'三氯半乳蔗糖和4,1',6'三氯半乳蔗糖的改良方法
US20080004439A1 (en) * 2005-01-03 2008-01-03 Rakesh Ratnam Sucrose-6-Ester Chlorination by Co-Addition of Chlorination Reagent
US20060188629A1 (en) * 2005-01-21 2006-08-24 Greg Liesen Method for the purification of sucralose
CN101166748A (zh) * 2005-02-22 2008-04-23 法马德医疗保险私人有限公司 在生产氯化蔗糖、其前体和衍生物过程的不同步骤中的分子分离方法
US20060205936A1 (en) * 2005-03-14 2006-09-14 Sl Laboratories, Llc Chlorination of Sucrose-6-esters
US20060247180A1 (en) * 2005-04-29 2006-11-02 Bergey James L Purgative composition and uses thereof
WO2007026377A2 (fr) * 2005-05-04 2007-03-08 Pharmed Medicare Private Limited Synthese d'un reactif de vilsmeier-haack a partir de carbonate de di(trichloromethyle) pour reaction de chloration
JP2008542199A (ja) * 2005-05-04 2008-11-27 ファームド メディケア プライヴェート リミテッド 五塩化リンとｄｍｆからの副生成物としてのオキシ塩化リンの生成及びビルスマイヤー・ハック試薬への変換による塩素化反応のためのその使用
GB2441917A (en) * 2005-06-01 2008-03-19 Pharmed Medicare Pvt Ltd Method for purification of chlorinated sucrose derivatives by solvent extraction
US20060276639A1 (en) * 2005-06-01 2006-12-07 Healthy Brands, Llc Conversion of sucralose-6-ester to sucralose
WO2007057920A2 (fr) * 2005-09-22 2007-05-24 Pharmed Medicare Pvt. Ltd. Nouveau procede de fabrication de 6-o-acyle chlorosucrose a partir d’une masse reactionnelle chloree anhydre
US20070100139A1 (en) * 2005-10-31 2007-05-03 Healthy Brands, Llc Methods for chlorinating sucrose-6-ester
US7741477B2 (en) * 2006-01-10 2010-06-22 Alembic Limited Process for purification of sucralose
WO2007099557A2 (fr) * 2006-02-28 2007-09-07 V. B. Medicare Pvt. Ltd. Nouveau réactif de chloration et nouveau procédé de chloration de sucres utilisant du chlorure de thionyle
CN100418976C (zh) * 2006-04-03 2008-09-17 广州科宏食品添加物有限公司 一种三氯蔗糖的制备方法
CN100402541C (zh) * 2006-06-15 2008-07-16 浙江工业大学 一种三氯蔗糖-6-乙酯的合成方法
CN101092438A (zh) * 2006-06-22 2007-12-26 南京莱因医药科技有限公司 6－o－苯甲酰三氯半乳型蔗糖四乙酯的制备方法
BRPI0621844A2 (pt) * 2006-07-06 2013-03-19 Alembic Ltd processo aperfeiÇoado para a preparaÇço de sucralose de alta pureza
CN100420697C (zh) * 2006-08-30 2008-09-24 河北苏科瑞科技有限公司 一种制备蔗糖-6-有机酸酯的方法
US20080103295A1 (en) * 2006-10-25 2008-05-01 David Losan Ho Process for the preparation of sucrose-6-ester by esterification in the presence of solid superacid catalyst
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US20080227971A1 (en) * 2007-01-19 2008-09-18 Leinhos Duane A Deacylation of sucralose-6-acylates
CN101260127B (zh) * 2007-03-06 2011-04-20 盐城捷康三氯蔗糖制造有限公司 由三氯蔗糖-6-乙酯脱乙酰基合成三氯蔗糖的方法
US20080300401A1 (en) * 2007-06-04 2008-12-04 Polymed Therapeutics, Inc. Novel chlorination process for preparing sucralose
US20080300392A1 (en) * 2007-06-04 2008-12-04 Polymed Therapeutics, Inc. Novel chlorination process for preparing sucralose
AR070082A1 (es) * 2008-01-04 2010-03-10 Tate & Lyle Technology Ltd Metodo para la produccion de sucralosa
US7932380B2 (en) * 2008-03-06 2011-04-26 Wanhe International (Group) Co. Ltd. Process for the preparation of sucralose
US8557976B2 (en) * 2008-03-13 2013-10-15 Tate & Lyle Technology Limited Microbial consortia and methods for their use
EP2254677A1 (fr) * 2008-03-20 2010-12-01 Tate & Lyle Technology Limited Élimination d acides de solvants amide tertiaire
US8436157B2 (en) * 2008-03-26 2013-05-07 Tate & Lyle Technology Limited Method for the production of sucralose
AR071134A1 (es) * 2008-04-03 2010-05-26 Tate & Lyle Technology Ltd Cristalizacion de sucralosa a partir de chorros que contienen sucralosa
US20090259036A1 (en) * 2008-04-03 2009-10-15 Tate & Lyle Technology Limited Extraction of less polar impurities from sucralose containing aqueous feed streams
US8497367B2 (en) * 2008-04-03 2013-07-30 Tate & Lyle Technology Limited Sucralose purification process
US20090299055A1 (en) * 2008-04-03 2009-12-03 Tate & Lyle Technology Limited Purification of Sucralose Containing Feed Streams for Sucralose Crystallization
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US20100022765A1 (en) * 2008-07-23 2010-01-28 David Losan Ho Methods for extracting and purifying sucralose intermediate
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GB2469157B (en) 2009-03-30 2011-07-06 John Kerr Process for removing dimethylamine during sucralose production
GB2469158B (en) * 2009-03-31 2011-09-28 Peter J Seaberg Base-assisted formation of tin-sucrose adducts
GB2471348B (en) * 2009-06-22 2011-12-14 Tate & Lyle Technology Ltd A method for producing sucralose-6-acylate
GB2474311B (en) 2009-10-12 2012-10-17 Tate & Lyle Technology Ltd Low temperature, single solvent process for the production of sucrose-6-ester
GB2474310B (en) 2009-10-12 2012-02-29 Tate & Lyle Technology Ltd Process for the production of sucrose-6-ester
US9120876B2 (en) * 2010-08-25 2015-09-01 Ramamohan Rao Davuluri Process for preparation of Sugammadex
CA2817630C (fr) 2010-11-23 2019-09-03 Lexington Pharmaceuticals Laboratories, Llc Chloration de glucides a basse temperature
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JP5679447B2 (ja) * 2011-06-20 2015-03-04 第一工業製薬株式会社 ショ糖ベンゾエート組成物の製造方法
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CN102964396B (zh) * 2012-10-26 2015-11-18 溧阳维信生物科技有限公司 一种三氯蔗糖-6-乙酯重结晶的方法
JP6109531B2 (ja) * 2012-11-02 2017-04-05 第一工業製薬株式会社 溶媒の除去方法
CN103145772A (zh) * 2013-03-26 2013-06-12 山东金城柯瑞化学有限公司 三氯蔗糖的制备方法
GB2539112B (en) 2013-12-16 2020-11-04 Tate & Lyle Tech Ltd Chlorination of sucrose-6-esters
GB2544217B (en) * 2014-08-08 2020-03-25 Tate & Lyle Tech Ltd Chlorination of sucrose-6-esters
CN104387427A (zh) * 2014-10-30 2015-03-04 安徽金禾实业股份有限公司 一种三氯蔗糖的生产方法
GB2536480B (en) 2015-03-17 2019-09-04 Tate & Lyle Tech Ltd DMF Distillation
CN105131050B (zh) * 2015-07-22 2018-07-31 青岛科技大学 一种氯化剂的制备方法及其制备三氯蔗糖的方法
CN105859802B (zh) * 2016-05-14 2019-02-12 广西科技大学 一种三氯蔗糖的结晶和纯化方法
GB2551591B (en) 2016-06-23 2019-08-07 Tate & Lyle Tech Ltd Liquid-liquid extraction of DMF
WO2022067621A1 (fr) 2020-09-30 2022-04-07 安徽金禾实业股份有限公司 Procédé de purification de sucralose
CN113699196A (zh) * 2021-08-17 2021-11-26 安徽金禾实业股份有限公司 一种蔗糖-6-乙酸酯的无水酶法催化合成方法

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EP0010410B1 (fr) * 1978-10-18 1982-03-03 TATE & LYLE PATENT HOLDINGS LIMITED Méthode de préparation de 2-chloro-2-déoxy saccharides et quelques 2-chloro-2-déoxy saccharides
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US4345933A (en) * 1980-01-28 1982-08-24 Velsicol Chemical Corporation Sucrose ester of 2-methoxy-3,6-dichlorobenzoic acid
EP0043649B1 (fr) * 1980-07-08 1984-09-12 TATE & LYLE PUBLIC LIMITED COMPANY Procédé pour la préparation de 4,1',6'-trichloro-4,1',6'-tridésoxygalactosucrose (TGS)
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GB8316790D0 (en) * 1983-06-21 1983-07-27 Tate & Lyle Plc Chemical process
GB8622345D0 (en) * 1986-09-17 1986-10-22 Tate & Lyle Plc Sucrose derivatives

Also Published As

Publication number Publication date
NO903190L (no) 1991-01-21
US4980463A (en) 1990-12-25
NO175532B (no) 1994-07-18
YU47948B (sh) 1996-07-24
PH26799A (en) 1992-10-13
RU1836377C (ru) 1993-08-23
TR28705A (tr) 1997-01-27
IL94994A0 (en) 1991-06-10
MX164442B (es) 1992-08-13
NO175532C (no) 1994-10-26
DE69024868D1 (de) 1996-02-29
AU625908B2 (en) 1992-07-16
CA2021632C (fr) 2000-09-12
KR910002885A (ko) 1991-02-26
IE69961B1 (en) 1996-10-16
PE21591A1 (es) 1991-07-22
EP0409549A3 (en) 1992-08-26
KR0144344B1 (ko) 1998-07-01
YU141190A (sh) 1992-07-20
FI903603A0 (fi) 1990-07-17
NO903190D0 (no) 1990-07-17
NZ234468A (en) 1992-01-29
IE902603A1 (en) 1991-02-27
DK0409549T3 (da) 1996-02-12
FI95802C (fi) 1996-03-25
AR247401A1 (es) 1994-12-29
JP3183506B2 (ja) 2001-07-09
CA2021632A1 (fr) 1991-01-19
AU5906990A (en) 1991-01-24
ES2088973T3 (es) 1996-10-01
GR1002037B (en) 1995-10-31
EP0409549A2 (fr) 1991-01-23
TW219939B (fr) 1994-02-01
PT94719B (pt) 1997-04-30
PT94719A (pt) 1991-03-20
DE69024868T2 (de) 1996-07-11
GR900100537A (el) 1991-12-10
IL94994A (en) 1994-06-24
JPH03218388A (ja) 1991-09-25
EP0409549B1 (fr) 1996-01-17
FI95802B (fi) 1995-12-15
ATE133175T1 (de) 1996-02-15

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