ZA9010392B - Method for the modification of the expression characteristics of an endogenous gene of given cell line or microorganism - Google Patents

Method for the modification of the expression characteristics of an endogenous gene of given cell line or microorganism

Info

Publication number
ZA9010392B
ZA9010392B ZA9010392A ZA9010392A ZA9010392B ZA 9010392 B ZA9010392 B ZA 9010392B ZA 9010392 A ZA9010392 A ZA 9010392A ZA 9010392 A ZA9010392 A ZA 9010392A ZA 9010392 B ZA9010392 B ZA 9010392B
Authority
ZA
South Africa
Prior art keywords
microorganism
modification
cell line
endogenous gene
given cell
Prior art date
Application number
ZA9010392A
Other languages
English (en)
Inventor
Scott C Chappel
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23806064&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA9010392(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of ZA9010392B publication Critical patent/ZA9010392B/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
ZA9010392A 1989-12-22 1990-12-27 Method for the modification of the expression characteristics of an endogenous gene of given cell line or microorganism ZA9010392B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45478389A 1989-12-22 1989-12-22

Publications (1)

Publication Number Publication Date
ZA9010392B true ZA9010392B (en) 1992-01-29

Family

ID=23806064

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9010392A ZA9010392B (en) 1989-12-22 1990-12-27 Method for the modification of the expression characteristics of an endogenous gene of given cell line or microorganism

Country Status (26)

Country Link
EP (5) EP1484412A3 (lv)
JP (3) JP3501286B2 (lv)
KR (1) KR0176693B1 (lv)
AR (1) AR245776A1 (lv)
AT (2) ATE156189T1 (lv)
AU (1) AU645294B2 (lv)
BG (1) BG60624B1 (lv)
BR (1) BR9007937A (lv)
CA (1) CA2071989C (lv)
DE (3) DE69031172T2 (lv)
DK (2) DK0505500T3 (lv)
ES (2) ES2151463T5 (lv)
FI (1) FI107391B (lv)
GR (1) GR3025057T3 (lv)
HK (2) HK1000547A1 (lv)
HU (1) HU217212B (lv)
IL (4) IL96765A0 (lv)
LT (1) LT3998B (lv)
LV (1) LV10655B (lv)
NO (1) NO311896B1 (lv)
OA (1) OA09594A (lv)
RO (1) RO109864B1 (lv)
RU (1) RU2128227C1 (lv)
UA (1) UA42675C2 (lv)
WO (1) WO1991009955A1 (lv)
ZA (1) ZA9010392B (lv)

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