ZA897414B - Pteridines - Google Patents
PteridinesInfo
- Publication number
- ZA897414B ZA897414B ZA897414A ZA897414A ZA897414B ZA 897414 B ZA897414 B ZA 897414B ZA 897414 A ZA897414 A ZA 897414A ZA 897414 A ZA897414 A ZA 897414A ZA 897414 B ZA897414 B ZA 897414B
- Authority
- ZA
- South Africa
- Prior art keywords
- group
- pteridines
- substituted
- carbon atom
- excepting
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
- C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3833393A DE3833393A1 (de) | 1988-10-01 | 1988-10-01 | Verwendung von pteridinen zur verhinderung der primaeren und sekundaeren resistenz bei der chemotherapie und diese verbindungen enthaltende arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA897414B true ZA897414B (en) | 1991-06-26 |
Family
ID=6364156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA897414A ZA897414B (en) | 1988-10-01 | 1989-09-29 | Pteridines |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0362645B1 (fi) |
| JP (1) | JPH02256676A (fi) |
| KR (1) | KR910006289A (fi) |
| AT (1) | ATE106728T1 (fi) |
| AU (1) | AU620645B2 (fi) |
| DD (1) | DD299062A5 (fi) |
| DE (2) | DE3833393A1 (fi) |
| DK (1) | DK480489A (fi) |
| ES (1) | ES2056174T3 (fi) |
| FI (1) | FI92699C (fi) |
| HU (1) | HU205761B (fi) |
| IL (1) | IL91814A (fi) |
| MX (1) | MX9203034A (fi) |
| NO (1) | NO175979C (fi) |
| NZ (1) | NZ230833A (fi) |
| PT (1) | PT91836B (fi) |
| SU (1) | SU1720491A3 (fi) |
| UA (1) | UA8028A1 (fi) |
| ZA (1) | ZA897414B (fi) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69920757T2 (de) * | 1998-12-28 | 2005-12-15 | 4 AZA Bioscience N.V. | Immunosuppressive wirkungen von pteridinderivaten |
| US7276506B2 (en) | 1998-12-28 | 2007-10-02 | 4 Aza Bioscience Nv | Immunosuppressive effects of pteridine derivatives |
| DE10202468A1 (de) * | 2002-01-23 | 2004-09-30 | Faustus Forschungs Cie. Translational Cancer Research Gmbh | Pteridinderivate, Verfahren zu deren Herstellung und ihre Verwendung |
| PT1663244E (pt) * | 2003-09-12 | 2007-11-15 | 4 Aza Ip Nv | Derivados de ptiridina para o tratamento de doenças relacionadas com o tnf-alfa |
| EP1673092B1 (en) * | 2003-10-17 | 2007-08-15 | 4 Aza Ip Nv | Heterocycle-substituted pteridine derivatives and their use in therapy |
| RU2447074C2 (ru) * | 2005-05-12 | 2012-04-10 | Тиботек Фармасьютикалз Лтд. | Птеридины, полезные в качестве ингибиторов hcv, и способы получения птеридинов |
| US9259426B2 (en) | 2006-07-20 | 2016-02-16 | Gilead Sciences, Inc. | 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections |
| US10144736B2 (en) | 2006-07-20 | 2018-12-04 | Gilead Sciences, Inc. | Substituted pteridines useful for the treatment and prevention of viral infections |
| SI3321265T1 (sl) | 2015-03-04 | 2020-07-31 | Gilead Sciences, Inc. | Spojine 4,6-diamino-pirido(3,2-d)pirimidina in njihova uporaba kot modulatorji toličnih receptorjev |
| KR20160003575A (ko) | 2015-11-09 | 2016-01-11 | 정민시 | 발전기용 동력전달장치 |
| US10640499B2 (en) | 2016-09-02 | 2020-05-05 | Gilead Sciences, Inc. | Toll like receptor modulator compounds |
| MA46093A (fr) | 2016-09-02 | 2021-05-19 | Gilead Sciences Inc | Composés modulateurs du recepteur de type toll |
| TWI751516B (zh) | 2019-04-17 | 2022-01-01 | 美商基利科學股份有限公司 | 類鐸受體調節劑之固體形式 |
| TW202212339A (zh) | 2019-04-17 | 2022-04-01 | 美商基利科學股份有限公司 | 類鐸受體調節劑之固體形式 |
| TW202115056A (zh) | 2019-06-28 | 2021-04-16 | 美商基利科學股份有限公司 | 類鐸受體調節劑化合物的製備方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3574206A (en) * | 1965-04-15 | 1971-04-06 | Boehringer Sohn Ingelheim | 2,7-dimorpholino-4-amino-6-phenyl-pteridines |
| NL129630C (fi) * | 1966-10-14 | |||
| DE1617336C2 (de) * | 1966-11-25 | 1982-07-01 | C.H. Boehringer Sohn, 6507 Ingelheim | Arzneimittel gegen Angina pectoris |
| DE1795515A1 (de) * | 1967-08-18 | 1972-03-30 | Thomae Gmbh Dr K | Verfahren zur Herstellung von neuen Pteridinen |
| DE1795516A1 (de) * | 1967-12-15 | 1972-01-27 | Thomae Gmbh Dr K | 4-AEthanolisopropanolamino-2-(2'-methylmorpholino)-7-morpholino-6-phenyl-pteridin |
| DE1921308A1 (de) * | 1969-04-25 | 1971-01-07 | Boehringer Sohn Ingelheim | Herzwirksame Zubereitungen |
| US4767761A (en) * | 1987-11-04 | 1988-08-30 | Dana-Farber Cancer Institute, Inc. | Ornithine derivatives and their use as methotrexate-resistant cell inhibitors |
-
1988
- 1988-10-01 DE DE3833393A patent/DE3833393A1/de not_active Withdrawn
-
1989
- 1989-09-23 DE DE58907824T patent/DE58907824D1/de not_active Expired - Fee Related
- 1989-09-23 AT AT89117610T patent/ATE106728T1/de not_active IP Right Cessation
- 1989-09-23 ES ES89117610T patent/ES2056174T3/es not_active Expired - Lifetime
- 1989-09-23 EP EP89117610A patent/EP0362645B1/de not_active Expired - Lifetime
- 1989-09-26 AU AU41749/89A patent/AU620645B2/en not_active Ceased
- 1989-09-28 IL IL9181489A patent/IL91814A/en not_active IP Right Cessation
- 1989-09-28 PT PT91836A patent/PT91836B/pt not_active IP Right Cessation
- 1989-09-29 KR KR1019890014002A patent/KR910006289A/ko not_active Application Discontinuation
- 1989-09-29 SU SU894742036A patent/SU1720491A3/ru active
- 1989-09-29 ZA ZA897414A patent/ZA897414B/xx unknown
- 1989-09-29 NO NO893879A patent/NO175979C/no unknown
- 1989-09-29 HU HU895131A patent/HU205761B/hu not_active IP Right Cessation
- 1989-09-29 DK DK480489A patent/DK480489A/da not_active Application Discontinuation
- 1989-09-29 NZ NZ230833A patent/NZ230833A/en unknown
- 1989-09-29 DD DD89333128A patent/DD299062A5/de not_active IP Right Cessation
- 1989-09-29 FI FI894615A patent/FI92699C/fi not_active IP Right Cessation
- 1989-09-29 UA UA4742036A patent/UA8028A1/uk unknown
- 1989-09-29 JP JP1255126A patent/JPH02256676A/ja active Pending
-
1992
- 1992-06-19 MX MX9203034A patent/MX9203034A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH02256676A (ja) | 1990-10-17 |
| ATE106728T1 (de) | 1994-06-15 |
| FI92699C (fi) | 1994-12-27 |
| DE3833393A1 (de) | 1990-04-05 |
| EP0362645B1 (de) | 1994-06-08 |
| DE58907824D1 (de) | 1994-07-14 |
| NO893879L (no) | 1990-04-02 |
| AU4174989A (en) | 1990-04-05 |
| NO175979B (no) | 1994-10-03 |
| EP0362645A2 (de) | 1990-04-11 |
| FI92699B (fi) | 1994-09-15 |
| FI894615A0 (fi) | 1989-09-29 |
| IL91814A (en) | 1994-02-27 |
| IL91814A0 (en) | 1990-06-10 |
| EP0362645A3 (de) | 1992-03-25 |
| PT91836B (pt) | 1995-07-18 |
| AU620645B2 (en) | 1992-02-20 |
| HU205761B (en) | 1992-06-29 |
| DD299062A5 (de) | 1992-03-26 |
| HUT52504A (en) | 1990-07-28 |
| NZ230833A (en) | 1991-05-28 |
| DK480489A (da) | 1990-04-02 |
| FI894615A (fi) | 1990-04-02 |
| DK480489D0 (da) | 1989-09-29 |
| NO893879D0 (no) | 1989-09-29 |
| NO175979C (no) | 1995-01-11 |
| ES2056174T3 (es) | 1994-10-01 |
| MX9203034A (es) | 1992-07-01 |
| SU1720491A3 (ru) | 1992-03-15 |
| KR910006289A (ko) | 1991-04-29 |
| PT91836A (pt) | 1990-04-30 |
| UA8028A1 (uk) | 1995-12-26 |
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