MX9203034A - Pteridinas que evitan la resistencia primaria y secundaria en la quimioterapia y medicamentos que las contienen. - Google Patents

Pteridinas que evitan la resistencia primaria y secundaria en la quimioterapia y medicamentos que las contienen.

Info

Publication number
MX9203034A
MX9203034A MX9203034A MX9203034A MX9203034A MX 9203034 A MX9203034 A MX 9203034A MX 9203034 A MX9203034 A MX 9203034A MX 9203034 A MX9203034 A MX 9203034A MX 9203034 A MX9203034 A MX 9203034A
Authority
MX
Mexico
Prior art keywords
pteridines
group
chemotherapy
substituted
carbon atom
Prior art date
Application number
MX9203034A
Other languages
English (en)
Inventor
Armin Dr Heckel
Jorg Dr Lebsanft
Uwe Dr Bamberger
Avner Dr Ramu
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of MX9203034A publication Critical patent/MX9203034A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MX9203034A 1988-10-01 1992-06-19 Pteridinas que evitan la resistencia primaria y secundaria en la quimioterapia y medicamentos que las contienen. MX9203034A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3833393A DE3833393A1 (de) 1988-10-01 1988-10-01 Verwendung von pteridinen zur verhinderung der primaeren und sekundaeren resistenz bei der chemotherapie und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
MX9203034A true MX9203034A (es) 1992-07-01

Family

ID=6364156

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9203034A MX9203034A (es) 1988-10-01 1992-06-19 Pteridinas que evitan la resistencia primaria y secundaria en la quimioterapia y medicamentos que las contienen.

Country Status (19)

Country Link
EP (1) EP0362645B1 (es)
JP (1) JPH02256676A (es)
KR (1) KR910006289A (es)
AT (1) ATE106728T1 (es)
AU (1) AU620645B2 (es)
DD (1) DD299062A5 (es)
DE (2) DE3833393A1 (es)
DK (1) DK480489A (es)
ES (1) ES2056174T3 (es)
FI (1) FI92699C (es)
HU (1) HU205761B (es)
IL (1) IL91814A (es)
MX (1) MX9203034A (es)
NO (1) NO175979C (es)
NZ (1) NZ230833A (es)
PT (1) PT91836B (es)
SU (1) SU1720491A3 (es)
UA (1) UA8028A1 (es)
ZA (1) ZA897414B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7276506B2 (en) 1998-12-28 2007-10-02 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
ATE277929T1 (de) * 1998-12-28 2004-10-15 4 Aza Bioscience Nv Immunsuppressive wirkungen von pteridinderivaten
DE10202468A1 (de) * 2002-01-23 2004-09-30 Faustus Forschungs Cie. Translational Cancer Research Gmbh Pteridinderivate, Verfahren zu deren Herstellung und ihre Verwendung
DE602004008304T2 (de) * 2003-09-12 2008-05-08 4 Aza Ip Nv Pteridin-derivate zur behandlung von erkrankungen im zusammenhang mit tnf-alpha
PT1673092E (pt) * 2003-10-17 2007-11-23 4 Aza Ip Nv ''derivados de pteridina substituídos com heterociclos e sua utilização em terapia''
RU2447074C2 (ru) * 2005-05-12 2012-04-10 Тиботек Фармасьютикалз Лтд. Птеридины, полезные в качестве ингибиторов hcv, и способы получения птеридинов
US10144736B2 (en) 2006-07-20 2018-12-04 Gilead Sciences, Inc. Substituted pteridines useful for the treatment and prevention of viral infections
EP3097102B1 (en) 2015-03-04 2017-10-18 Gilead Sciences, Inc. Toll-like receptor modulating 4,6-diamino-pyrido[3,2-d]pyrimidine compounds
KR20160003575A (ko) 2015-11-09 2016-01-11 정민시 발전기용 동력전달장치
EP3507276B1 (en) 2016-09-02 2021-11-03 Gilead Sciences, Inc. Toll like receptor modulator compounds
US10640499B2 (en) 2016-09-02 2020-05-05 Gilead Sciences, Inc. Toll like receptor modulator compounds
TWI751516B (zh) 2019-04-17 2022-01-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TWI751517B (zh) 2019-04-17 2022-01-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202115056A (zh) 2019-06-28 2021-04-16 美商基利科學股份有限公司 類鐸受體調節劑化合物的製備方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3574206A (en) * 1965-04-15 1971-04-06 Boehringer Sohn Ingelheim 2,7-dimorpholino-4-amino-6-phenyl-pteridines
NL129630C (es) * 1966-10-14
DE1617336C2 (de) * 1966-11-25 1982-07-01 C.H. Boehringer Sohn, 6507 Ingelheim Arzneimittel gegen Angina pectoris
DE1795515A1 (de) * 1967-08-18 1972-03-30 Thomae Gmbh Dr K Verfahren zur Herstellung von neuen Pteridinen
DE1795516A1 (de) * 1967-12-15 1972-01-27 Thomae Gmbh Dr K 4-AEthanolisopropanolamino-2-(2'-methylmorpholino)-7-morpholino-6-phenyl-pteridin
DE1921308A1 (de) * 1969-04-25 1971-01-07 Boehringer Sohn Ingelheim Herzwirksame Zubereitungen
US4767761A (en) * 1987-11-04 1988-08-30 Dana-Farber Cancer Institute, Inc. Ornithine derivatives and their use as methotrexate-resistant cell inhibitors

Also Published As

Publication number Publication date
AU4174989A (en) 1990-04-05
FI894615A (fi) 1990-04-02
IL91814A (en) 1994-02-27
FI894615A0 (fi) 1989-09-29
DE3833393A1 (de) 1990-04-05
SU1720491A3 (ru) 1992-03-15
JPH02256676A (ja) 1990-10-17
FI92699C (fi) 1994-12-27
PT91836A (pt) 1990-04-30
NO893879D0 (no) 1989-09-29
EP0362645A3 (de) 1992-03-25
UA8028A1 (uk) 1995-12-26
DK480489D0 (da) 1989-09-29
AU620645B2 (en) 1992-02-20
KR910006289A (ko) 1991-04-29
NO893879L (no) 1990-04-02
HUT52504A (en) 1990-07-28
ZA897414B (en) 1991-06-26
HU205761B (en) 1992-06-29
DD299062A5 (de) 1992-03-26
EP0362645B1 (de) 1994-06-08
IL91814A0 (en) 1990-06-10
NO175979C (no) 1995-01-11
ES2056174T3 (es) 1994-10-01
FI92699B (fi) 1994-09-15
PT91836B (pt) 1995-07-18
EP0362645A2 (de) 1990-04-11
DE58907824D1 (de) 1994-07-14
NZ230833A (en) 1991-05-28
ATE106728T1 (de) 1994-06-15
DK480489A (da) 1990-04-02
NO175979B (no) 1994-10-03

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