ZA892674B - Amides of cyclomethylen-1,2-dicarboxylic acids having therapeutical activity,processes for their preparation and pharmaceutical compositions containing them - Google Patents
Amides of cyclomethylen-1,2-dicarboxylic acids having therapeutical activity,processes for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- ZA892674B ZA892674B ZA892674A ZA892674A ZA892674B ZA 892674 B ZA892674 B ZA 892674B ZA 892674 A ZA892674 A ZA 892674A ZA 892674 A ZA892674 A ZA 892674A ZA 892674 B ZA892674 B ZA 892674B
- Authority
- ZA
- South Africa
- Prior art keywords
- cyclomethylen
- amides
- preparation
- processes
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/61—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Eyeglasses (AREA)
- Polyamides (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8820172A IT1224627B (it) | 1988-04-12 | 1988-04-12 | Ammidi di acidi ciclometilen_1,2_dicarbossilici adattivita' terapeutica, procedimenti per la loro preparazione e composizioni farmaceutiche che le contengono. |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA892674B true ZA892674B (en) | 1989-12-27 |
Family
ID=11164400
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA892674A ZA892674B (en) | 1988-04-12 | 1989-04-12 | Amides of cyclomethylen-1,2-dicarboxylic acids having therapeutical activity,processes for their preparation and pharmaceutical compositions containing them |
Country Status (28)
Country | Link |
---|---|
US (1) | US5095137A (de) |
EP (1) | EP0337348B1 (de) |
JP (1) | JPH026452A (de) |
KR (1) | KR900016097A (de) |
CN (1) | CN1037344A (de) |
AT (1) | ATE101126T1 (de) |
AU (1) | AU611796B2 (de) |
BG (1) | BG60556B1 (de) |
CA (1) | CA1314903C (de) |
DD (1) | DD294014A5 (de) |
DE (1) | DE68912811T2 (de) |
DK (1) | DK173689A (de) |
ES (1) | ES2061759T3 (de) |
FI (1) | FI891712A (de) |
HU (1) | HU206194B (de) |
IL (1) | IL89895A0 (de) |
IN (2) | IN169836B (de) |
IT (1) | IT1224627B (de) |
MX (1) | MX15635A (de) |
NO (1) | NO177851C (de) |
NZ (1) | NZ228688A (de) |
PL (1) | PL159413B1 (de) |
PT (1) | PT90254B (de) |
RO (1) | RO104347B1 (de) |
RU (2) | RU2004538C1 (de) |
UA (1) | UA15920A (de) |
YU (1) | YU73889A (de) |
ZA (1) | ZA892674B (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1252708B (it) * | 1991-12-23 | 1995-06-26 | Guidotti & C Spa Labor | Sali stabili dell'acido (+)-(1r,2s)-2((n-(2-idrossilammino-2-ossoetil)-n-metilammino)carbonil)cicloesan-1-carbossilico,ad attivita' ace inibitrice, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono. |
US5977160A (en) * | 1992-04-10 | 1999-11-02 | Brigham And Women's Hospital, Inc. | Methods for reducing risk of repeat myocardial infarction and increasing survival in heart attack victims |
IT1264860B1 (it) * | 1993-06-21 | 1996-10-17 | Guidotti & C Spa Labor | Derivati di acidi cis- e trans-2(((2-(isdrossiammino)-2-ossoetil)- alchilammino)carbonil)cicloesancarbossilici |
US5639746A (en) * | 1994-12-29 | 1997-06-17 | The Procter & Gamble Company | Hydroxamic acid-containing inhibitors of matrix metalloproteases |
US6028213A (en) | 1998-04-16 | 2000-02-22 | Eastman Chemical Company | Optically active cis-1,3-cyclohexanedicarboxylic acid monoesters with high enantiomeric purity and process for their preparation |
AU2007279092B2 (en) * | 2006-07-24 | 2012-12-13 | Ucb Pharma S.A. | Substituted aniline derivatives |
US20100168243A1 (en) * | 2007-06-20 | 2010-07-01 | Baldwin John J | Renin Inhibitors |
WO2008156816A2 (en) | 2007-06-20 | 2008-12-24 | Vitae Pharmaceuticals, Inc. | Renin inhibitors |
AU2009204427B2 (en) | 2008-01-08 | 2013-10-03 | Lantheus Medical Imaging, Inc. | N-alkoxyamide conjugates as imaging agents |
JP5676600B2 (ja) | 2009-07-08 | 2015-02-25 | ランセウス メディカル イメージング, インコーポレイテッド | 造影剤としてのn−アルコキシアミド抱合体 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4077998A (en) * | 1975-10-28 | 1978-03-07 | Morton-Norwich Products, Inc. | Phthaloyl amino acid hydroxamic acids |
US4687841A (en) * | 1985-10-18 | 1987-08-18 | Monsanto Company | Peptide hydroxamic acid derivatives |
-
1988
- 1988-04-12 IT IT8820172A patent/IT1224627B/it active
-
1989
- 1989-04-10 DE DE68912811T patent/DE68912811T2/de not_active Expired - Fee Related
- 1989-04-10 IL IL89895A patent/IL89895A0/xx not_active IP Right Cessation
- 1989-04-10 ES ES89106304T patent/ES2061759T3/es not_active Expired - Lifetime
- 1989-04-10 EP EP89106304A patent/EP0337348B1/de not_active Expired - Lifetime
- 1989-04-10 AT AT89106304T patent/ATE101126T1/de not_active IP Right Cessation
- 1989-04-11 HU HU891735A patent/HU206194B/hu not_active IP Right Cessation
- 1989-04-11 UA UA4614855A patent/UA15920A/uk unknown
- 1989-04-11 CA CA000596331A patent/CA1314903C/en not_active Expired - Fee Related
- 1989-04-11 NZ NZ228688A patent/NZ228688A/en unknown
- 1989-04-11 PT PT90254A patent/PT90254B/pt not_active IP Right Cessation
- 1989-04-11 NO NO891484A patent/NO177851C/no unknown
- 1989-04-11 FI FI891712A patent/FI891712A/fi not_active Application Discontinuation
- 1989-04-11 RU SU894613962A patent/RU2004538C1/ru active
- 1989-04-11 DK DK173689A patent/DK173689A/da not_active IP Right Cessation
- 1989-04-12 ZA ZA892674A patent/ZA892674B/xx unknown
- 1989-04-12 IN IN283/CAL/89A patent/IN169836B/en unknown
- 1989-04-12 JP JP1092774A patent/JPH026452A/ja active Pending
- 1989-04-12 CN CN89102213A patent/CN1037344A/zh active Pending
- 1989-04-12 DD DD89327552A patent/DD294014A5/de not_active IP Right Cessation
- 1989-04-12 RO RO139231A patent/RO104347B1/ro unknown
- 1989-04-12 PL PL1989278804A patent/PL159413B1/pl unknown
- 1989-04-12 MX MX1563589A patent/MX15635A/es unknown
- 1989-04-12 YU YU00738/89A patent/YU73889A/xx unknown
- 1989-04-12 BG BG88028A patent/BG60556B1/bg unknown
- 1989-04-12 KR KR1019890004818A patent/KR900016097A/ko not_active Application Discontinuation
- 1989-04-12 AU AU32655/89A patent/AU611796B2/en not_active Ceased
- 1989-08-28 RU SU894614855A patent/RU1838294C/ru active
-
1990
- 1990-10-09 US US07/595,639 patent/US5095137A/en not_active Expired - Fee Related
- 1990-11-29 IN IN1000/CAL/90A patent/IN172059B/en unknown
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