ZA862941B - (-)-1beta-ethyl-1alpha-hydroxymethyl-1,2,3,4,6,7,12,12b alpha-octahydroindolo(2,3-a)quinolizine,process for its preparation and pharmaceutical compositions containing same - Google Patents

(-)-1beta-ethyl-1alpha-hydroxymethyl-1,2,3,4,6,7,12,12b alpha-octahydroindolo(2,3-a)quinolizine,process for its preparation and pharmaceutical compositions containing same

Info

Publication number
ZA862941B
ZA862941B ZA862941A ZA862941A ZA862941B ZA 862941 B ZA862941 B ZA 862941B ZA 862941 A ZA862941 A ZA 862941A ZA 862941 A ZA862941 A ZA 862941A ZA 862941 B ZA862941 B ZA 862941B
Authority
ZA
South Africa
Prior art keywords
octahydroindolo
1alpha
1beta
quinolizine
hydroxymethyl
Prior art date
Application number
ZA862941A
Other languages
English (en)
Inventor
Csaba Szantay
Lajos Szabo
Gyoergy Kalaus
Zsolt Szombathelyi
Egon Karpati
Bela Kiss
Katalin Csomor
Istvan Laszlovsky
Erzsebet Lapis
Laszlo Szporny
Lilla Forgacs
Csaba Kuthi
Aniko Gere
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of ZA862941B publication Critical patent/ZA862941B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
ZA862941A 1985-04-19 1986-04-18 (-)-1beta-ethyl-1alpha-hydroxymethyl-1,2,3,4,6,7,12,12b alpha-octahydroindolo(2,3-a)quinolizine,process for its preparation and pharmaceutical compositions containing same ZA862941B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU851519A HU194221B (en) 1985-04-19 1985-04-19 Process for preparing novel octahydro-indolo/2,3-a/quinoline derivative and pharmaceutical comprising this compound

Publications (1)

Publication Number Publication Date
ZA862941B true ZA862941B (en) 1986-12-30

Family

ID=10954847

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA862941A ZA862941B (en) 1985-04-19 1986-04-18 (-)-1beta-ethyl-1alpha-hydroxymethyl-1,2,3,4,6,7,12,12b alpha-octahydroindolo(2,3-a)quinolizine,process for its preparation and pharmaceutical compositions containing same

Country Status (35)

Country Link
US (1) US4806545A (hu)
JP (1) JPH072637B2 (hu)
CN (1) CN1023560C (hu)
AR (1) AR240699A1 (hu)
AT (1) AT390954B (hu)
AU (1) AU591896B2 (hu)
BE (1) BE904588A (hu)
BG (1) BG60433B2 (hu)
CA (1) CA1299574C (hu)
CH (1) CH668262A5 (hu)
CS (1) CS274276B2 (hu)
DD (1) DD244556A5 (hu)
DE (1) DE3613180C2 (hu)
DK (1) DK159780C (hu)
EG (1) EG18059A (hu)
ES (1) ES8706152A1 (hu)
FI (1) FI83870C (hu)
FR (1) FR2580649B1 (hu)
GB (1) GB2174701B (hu)
GR (1) GR861027B (hu)
HU (1) HU194221B (hu)
IE (1) IE59199B1 (hu)
IL (1) IL78538A (hu)
IN (1) IN162810B (hu)
IT (1) IT1204306B (hu)
LU (1) LU86397A1 (hu)
NL (1) NL8600976A (hu)
NO (1) NO167143C (hu)
NZ (1) NZ215879A (hu)
PH (1) PH25316A (hu)
PT (1) PT82424B (hu)
SE (1) SE460196B (hu)
SU (1) SU1438612A3 (hu)
YU (1) YU44286B (hu)
ZA (1) ZA862941B (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU191454B (en) * 1984-10-05 1987-02-27 Richter Gedeon Vegyeszeti Gyar Rt.,Hu Process for producing amides of oktahydro-indolo/2,3-a/quinolyzin-1-yl-alkanecarboxylic acids and pharmaceutically acceptable acid additional salts thereof
HU195214B (en) * 1985-04-19 1988-04-28 Richter Gedeon Vegyeszet Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds
HU194220B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof
HU207070B (en) * 1990-10-31 1993-03-01 Richter Gedeon Vegyeszet Process for producing 1beta-ethyl-1alpha-hydroxymethyl-1,2,3,4,6,712,12balpha-octahydroindolo(2,3-a) quinolizine
DE19821039A1 (de) * 1998-05-11 1999-11-18 Bayer Ag Verfahren zur Herstellung von (S,S)-Benzyl-2,8-diazabicyclo[4.3.0]nonan
HUP0500201A2 (hu) * 2002-04-03 2005-07-28 Orion Corp. Policiklusos vegyületek, mint potenciális alfa2-adrenoceptor antagonisták és ezeket tartalmazó gyógyszerkészítmények
AU2003235931A1 (en) * 2002-05-13 2003-11-11 Takata Seiyaku Co., Ltd. Vintoperol-containing medicinal composition for transdermal administration

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU170495B (hu) * 1974-05-07 1977-06-28
GB1499546A (en) * 1974-05-07 1978-02-01 Richter Gedeon Vegyeszet Indolo-quinolizidine derivatives and a process for the preparation thereof
HU195214B (en) * 1985-04-19 1988-04-28 Richter Gedeon Vegyeszet Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds
HU194220B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof

Also Published As

Publication number Publication date
DK159780B (da) 1990-12-03
NZ215879A (en) 1989-04-26
PT82424B (pt) 1988-03-03
EG18059A (en) 1991-06-30
JPH072637B2 (ja) 1995-01-18
FI83870B (fi) 1991-05-31
AT390954B (de) 1990-07-25
GB2174701B (en) 1989-02-15
CN1023560C (zh) 1994-01-19
BE904588A (fr) 1986-10-14
CH668262A5 (de) 1988-12-15
CS286386A2 (en) 1990-09-12
DK179786A (da) 1986-10-20
AU5638386A (en) 1986-10-23
FI861641A (fi) 1986-10-20
DK159780C (da) 1991-04-22
HUT40433A (en) 1986-12-28
BG60433B2 (bg) 1995-03-31
SE8601799D0 (sv) 1986-04-18
DD244556A5 (de) 1987-04-08
GB2174701A (en) 1986-11-12
FR2580649B1 (fr) 1991-03-29
CN86102479A (zh) 1986-10-22
FI861641A0 (fi) 1986-04-18
LU86397A1 (hu) 1986-09-02
IL78538A (en) 1989-10-31
YU44286B (en) 1990-04-30
YU62486A (en) 1988-06-30
IE861033L (en) 1986-10-19
SE8601799L (sv) 1986-10-20
DK179786D0 (da) 1986-04-18
CS274276B2 (en) 1991-04-11
IT1204306B (it) 1989-03-01
JPS61249986A (ja) 1986-11-07
AR240699A1 (es) 1990-09-28
GB8609533D0 (en) 1986-05-21
IT8620136A0 (it) 1986-04-18
DE3613180A1 (de) 1986-10-23
NO167143B (no) 1991-07-01
DE3613180C2 (de) 1995-10-19
ES8706152A1 (es) 1987-06-01
PT82424A (en) 1986-05-01
NL8600976A (nl) 1986-11-17
FR2580649A1 (fr) 1986-10-24
AU591896B2 (en) 1989-12-21
IN162810B (hu) 1988-07-09
US4806545A (en) 1989-02-21
IL78538A0 (en) 1986-08-31
SE460196B (sv) 1989-09-18
HU194221B (en) 1988-01-28
NO861539L (no) 1986-10-20
PH25316A (en) 1991-04-30
ES554143A0 (es) 1987-06-01
FI83870C (fi) 1991-09-10
SU1438612A3 (ru) 1988-11-15
GR861027B (en) 1986-08-12
IE59199B1 (en) 1994-01-26
NO167143C (no) 1991-10-09
ATA102986A (de) 1990-01-15
CA1299574C (en) 1992-04-28

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