IT1204306B - (-)-1beta-etil-1alfa-idrossimentil-1,2,3,4,6,7,12,12balfa-ottaidroindolo (2,3-a)chinolizina,procedimento per la sua preparazione e composizioni farmaceutiche che la contengono - Google Patents

(-)-1beta-etil-1alfa-idrossimentil-1,2,3,4,6,7,12,12balfa-ottaidroindolo (2,3-a)chinolizina,procedimento per la sua preparazione e composizioni farmaceutiche che la contengono

Info

Publication number
IT1204306B
IT1204306B IT20136/86A IT2013686A IT1204306B IT 1204306 B IT1204306 B IT 1204306B IT 20136/86 A IT20136/86 A IT 20136/86A IT 2013686 A IT2013686 A IT 2013686A IT 1204306 B IT1204306 B IT 1204306B
Authority
IT
Italy
Prior art keywords
hydroximentyl
12balpha
octahydroindol
1alpha
1beta
Prior art date
Application number
IT20136/86A
Other languages
English (en)
Other versions
IT8620136A0 (it
Inventor
Csaba Szantay
Lajos Szabo
Gyorgy Kalaus
Zsolt Szombathelyi
Egon Karpati
Bela Kiss
Katalin Cscmor
Istvan Laszlovsky
Erzsebet Lapis
Laszlo Szporny
Lilla Forgacs
Csaba Kuthi
Aniko Gere
Original Assignee
Richter Cedeon Vegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Cedeon Vegyeszeti Gyar filed Critical Richter Cedeon Vegyeszeti Gyar
Publication of IT8620136A0 publication Critical patent/IT8620136A0/it
Application granted granted Critical
Publication of IT1204306B publication Critical patent/IT1204306B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
IT20136/86A 1985-04-19 1986-04-18 (-)-1beta-etil-1alfa-idrossimentil-1,2,3,4,6,7,12,12balfa-ottaidroindolo (2,3-a)chinolizina,procedimento per la sua preparazione e composizioni farmaceutiche che la contengono IT1204306B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU851519A HU194221B (en) 1985-04-19 1985-04-19 Process for preparing novel octahydro-indolo/2,3-a/quinoline derivative and pharmaceutical comprising this compound

Publications (2)

Publication Number Publication Date
IT8620136A0 IT8620136A0 (it) 1986-04-18
IT1204306B true IT1204306B (it) 1989-03-01

Family

ID=10954847

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20136/86A IT1204306B (it) 1985-04-19 1986-04-18 (-)-1beta-etil-1alfa-idrossimentil-1,2,3,4,6,7,12,12balfa-ottaidroindolo (2,3-a)chinolizina,procedimento per la sua preparazione e composizioni farmaceutiche che la contengono

Country Status (35)

Country Link
US (1) US4806545A (it)
JP (1) JPH072637B2 (it)
CN (1) CN1023560C (it)
AR (1) AR240699A1 (it)
AT (1) AT390954B (it)
AU (1) AU591896B2 (it)
BE (1) BE904588A (it)
BG (1) BG60433B2 (it)
CA (1) CA1299574C (it)
CH (1) CH668262A5 (it)
CS (1) CS274276B2 (it)
DD (1) DD244556A5 (it)
DE (1) DE3613180C2 (it)
DK (1) DK159780C (it)
EG (1) EG18059A (it)
ES (1) ES8706152A1 (it)
FI (1) FI83870C (it)
FR (1) FR2580649B1 (it)
GB (1) GB2174701B (it)
GR (1) GR861027B (it)
HU (1) HU194221B (it)
IE (1) IE59199B1 (it)
IL (1) IL78538A (it)
IN (1) IN162810B (it)
IT (1) IT1204306B (it)
LU (1) LU86397A1 (it)
NL (1) NL8600976A (it)
NO (1) NO167143C (it)
NZ (1) NZ215879A (it)
PH (1) PH25316A (it)
PT (1) PT82424B (it)
SE (1) SE460196B (it)
SU (1) SU1438612A3 (it)
YU (1) YU44286B (it)
ZA (1) ZA862941B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU191454B (en) * 1984-10-05 1987-02-27 Richter Gedeon Vegyeszeti Gyar Rt.,Hu Process for producing amides of oktahydro-indolo/2,3-a/quinolyzin-1-yl-alkanecarboxylic acids and pharmaceutically acceptable acid additional salts thereof
HU194220B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof
HU195214B (en) * 1985-04-19 1988-04-28 Richter Gedeon Vegyeszet Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds
HU207070B (en) 1990-10-31 1993-03-01 Richter Gedeon Vegyeszet Process for producing 1beta-ethyl-1alpha-hydroxymethyl-1,2,3,4,6,712,12balpha-octahydroindolo(2,3-a) quinolizine
DE19821039A1 (de) * 1998-05-11 1999-11-18 Bayer Ag Verfahren zur Herstellung von (S,S)-Benzyl-2,8-diazabicyclo[4.3.0]nonan
AU2003216760A1 (en) * 2002-04-03 2003-10-13 Orion Corporation Polycyclic compounds as potent alpha2-adrenoceptor antagonists
AU2003235931A1 (en) * 2002-05-13 2003-11-11 Takata Seiyaku Co., Ltd. Vintoperol-containing medicinal composition for transdermal administration

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU170495B (it) * 1974-05-07 1977-06-28
GB1499546A (en) * 1974-05-07 1978-02-01 Richter Gedeon Vegyeszet Indolo-quinolizidine derivatives and a process for the preparation thereof
HU194220B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof
HU195214B (en) * 1985-04-19 1988-04-28 Richter Gedeon Vegyeszet Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds

Also Published As

Publication number Publication date
ZA862941B (en) 1986-12-30
DD244556A5 (de) 1987-04-08
HUT40433A (en) 1986-12-28
IN162810B (it) 1988-07-09
NO167143B (no) 1991-07-01
DE3613180C2 (de) 1995-10-19
IT8620136A0 (it) 1986-04-18
FR2580649A1 (fr) 1986-10-24
AT390954B (de) 1990-07-25
YU62486A (en) 1988-06-30
NL8600976A (nl) 1986-11-17
GB2174701A (en) 1986-11-12
JPS61249986A (ja) 1986-11-07
CH668262A5 (de) 1988-12-15
BE904588A (fr) 1986-10-14
DE3613180A1 (de) 1986-10-23
SE8601799D0 (sv) 1986-04-18
AU5638386A (en) 1986-10-23
FR2580649B1 (fr) 1991-03-29
ATA102986A (de) 1990-01-15
CS286386A2 (en) 1990-09-12
GR861027B (en) 1986-08-12
JPH072637B2 (ja) 1995-01-18
GB8609533D0 (en) 1986-05-21
CN86102479A (zh) 1986-10-22
CA1299574C (en) 1992-04-28
IL78538A0 (en) 1986-08-31
DK159780C (da) 1991-04-22
DK159780B (da) 1990-12-03
DK179786D0 (da) 1986-04-18
IL78538A (en) 1989-10-31
LU86397A1 (it) 1986-09-02
BG60433B2 (bg) 1995-03-31
GB2174701B (en) 1989-02-15
CS274276B2 (en) 1991-04-11
ES8706152A1 (es) 1987-06-01
YU44286B (en) 1990-04-30
EG18059A (en) 1991-06-30
AR240699A1 (es) 1990-09-28
US4806545A (en) 1989-02-21
CN1023560C (zh) 1994-01-19
HU194221B (en) 1988-01-28
NO167143C (no) 1991-10-09
IE861033L (en) 1986-10-19
FI83870B (fi) 1991-05-31
FI861641A (fi) 1986-10-20
AU591896B2 (en) 1989-12-21
SE8601799L (sv) 1986-10-20
PT82424B (pt) 1988-03-03
DK179786A (da) 1986-10-20
ES554143A0 (es) 1987-06-01
SU1438612A3 (ru) 1988-11-15
IE59199B1 (en) 1994-01-26
NZ215879A (en) 1989-04-26
FI83870C (fi) 1991-09-10
SE460196B (sv) 1989-09-18
PH25316A (en) 1991-04-30
FI861641A0 (fi) 1986-04-18
PT82424A (en) 1986-05-01
NO861539L (no) 1986-10-20

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Legal Events

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970424