|
US4515810A
(en)
*
|
1983-10-06 |
1985-05-07 |
American Cyanamid Company |
Composition of matter
|
|
US5962490A
(en)
|
1987-09-25 |
1999-10-05 |
Texas Biotechnology Corporation |
Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
|
|
US5004651A
(en)
*
|
1989-01-24 |
1991-04-02 |
Abbott Laboratories |
Stabilizing system for solid dosage forms
|
|
AU645070B2
(en)
*
|
1990-04-10 |
1994-01-06 |
Nb International Technologies |
Use of short chain fatty acid containing lipids to maintain gastrointestinal integrity and function in patients DO NOT SEAL - SEE LETTER DATED 22.03.94
|
|
US6342610B2
(en)
|
1993-05-20 |
2002-01-29 |
Texas Biotechnology Corp. |
N-aryl thienyl-, furyl-, and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
|
|
IL131318A
(en)
|
1997-04-28 |
2004-08-31 |
Encysive Pharmaceuticals Inc |
Pharmaceutically acceptable salts of sulfonamides for treatment of endothelin-mediated disorders
|
|
US5783705A
(en)
|
1997-04-28 |
1998-07-21 |
Texas Biotechnology Corporation |
Process of preparing alkali metal salys of hydrophobic sulfonamides
|
|
US6362009B1
(en)
|
1997-11-21 |
2002-03-26 |
Merck & Co., Inc. |
Solid phase synthesis of heterocycles
|
|
US7169410B1
(en)
*
|
1998-05-19 |
2007-01-30 |
Sdg, Inc. |
Targeted liposomal drug delivery system
|
|
AU1624801A
(en)
|
1999-11-19 |
2001-05-30 |
Corvas International, Inc. |
Plasminogen activator inhibitor antagonists related applications
|
|
US6638977B1
(en)
|
1999-11-19 |
2003-10-28 |
Corvas International, Inc. |
Plasminogen activator inhibitor antagonists
|
|
US7897140B2
(en)
|
1999-12-23 |
2011-03-01 |
Health Research, Inc. |
Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
|
|
AUPR868201A0
(en)
*
|
2001-11-05 |
2001-11-29 |
Thorlock International Limited |
Q-factor switching method and apparatus for detecting nuclear quadrupole and nuclear magnetic resonance signals
|
|
JP5082033B2
(ja)
|
2001-12-21 |
2012-11-28 |
エグゼリクシス パテント カンパニー エルエルシー |
Lxrのモジュレーター
|
|
ES2367539T3
(es)
*
|
2001-12-21 |
2011-11-04 |
X-Ceptor Therapeutics, Inc. |
Moduladores heterocíclicos de receptores nucleares.
|
|
US7482366B2
(en)
|
2001-12-21 |
2009-01-27 |
X-Ceptor Therapeutics, Inc. |
Modulators of LXR
|
|
US20040001801A1
(en)
*
|
2002-05-23 |
2004-01-01 |
Corvas International, Inc. |
Conjugates activated by cell surface proteases and therapeutic uses thereof
|
|
CA2490692A1
(en)
|
2002-06-27 |
2004-01-08 |
Health Research, Inc. |
Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy
|
|
EP1606291A2
(en)
|
2002-07-02 |
2005-12-21 |
Health Research, Inc. |
Efficient synthesis of pyropheophorbide a and its dervatives
|
|
EP2163643B1
(en)
|
2003-03-05 |
2015-01-21 |
Halozyme, Inc. |
Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof
|
|
US20060104968A1
(en)
|
2003-03-05 |
2006-05-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
|
|
US20090123367A1
(en)
*
|
2003-03-05 |
2009-05-14 |
Delfmems |
Soluble Glycosaminoglycanases and Methods of Preparing and Using Soluble Glycosaminoglycanases
|
|
US7871607B2
(en)
|
2003-03-05 |
2011-01-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
|
|
CN102584813B
(zh)
*
|
2003-05-14 |
2016-07-06 |
Ngc药物公司 |
化合物及其在调节淀粉样蛋白β中的用途
|
|
US7652044B2
(en)
*
|
2003-06-03 |
2010-01-26 |
Novartis A.G. |
P-38 inhibitors
|
|
US7057100B2
(en)
*
|
2003-06-26 |
2006-06-06 |
The J.C. Robinson Seed Co. |
Inbred corn line W23129
|
|
EP1911754B1
(en)
|
2003-08-13 |
2013-10-09 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
|
US7420000B2
(en)
|
2003-09-10 |
2008-09-02 |
University Of Southern California |
Amino phosphonate and amino bis-phosphonate derivatives
|
|
US20050203184A1
(en)
*
|
2003-09-10 |
2005-09-15 |
Petasis Nicos A. |
Benzo lipoxin analogues
|
|
WO2005033093A1
(en)
|
2003-09-19 |
2005-04-14 |
Galileo Pharmaceuticals, Inc. |
7,8-bicycloalkyl-chroman derivatives
|
|
US20050148534A1
(en)
*
|
2003-09-22 |
2005-07-07 |
Castellino Angelo J. |
Small molecule compositions and methods for increasing drug efficiency using compositions thereof
|
|
WO2005090370A1
(en)
|
2004-02-05 |
2005-09-29 |
The Regents Of The University Of California |
Pharmacologically active agents containing esterified phosphonates and methods for use thereof
|
|
US8519158B2
(en)
*
|
2004-03-12 |
2013-08-27 |
Ligand Pharmaceuticals Incorporated |
Androgen receptor modulator compounds and methods
|
|
US7868033B2
(en)
|
2004-05-20 |
2011-01-11 |
Foldrx Pharmaceuticals, Inc. |
Compounds, compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding
|
|
WO2006009876A2
(en)
*
|
2004-06-17 |
2006-01-26 |
Cengent Therapeutics, Inc. |
Trisubstituted nitrogen modulators of tyrosine phosphatases
|
|
JP2008505916A
(ja)
*
|
2004-07-09 |
2008-02-28 |
メタバシス・セラピューティクス・インコーポレイテッド |
チロシンホスファターゼの酸素/窒素複素環阻害剤
|
|
AU2005271831A1
(en)
|
2004-07-12 |
2006-02-16 |
Idun Pharmaceuticals, Inc. |
Tetrapeptide analogs
|
|
US20060034978A1
(en)
*
|
2004-08-16 |
2006-02-16 |
Grain Processing Corporation |
Aerosol compositions, devices and methods
|
|
WO2006028970A1
(en)
|
2004-09-02 |
2006-03-16 |
Cengent Therapeutics, Inc. |
Derivatives of thiazole and thiadiazole inhibitors of tyrosine phosphatases
|
|
NZ588431A
(en)
|
2004-09-17 |
2012-02-24 |
Whitehead Biomedical Inst |
Using Benzimidazole or Indole compounds with a 1,2-diazole group to Inhibit Alpha-Synuclein Toxicity
|
|
ES2401285T3
(es)
*
|
2004-12-16 |
2013-04-18 |
The Regents Of The University Of California |
Fármacos con el pulmón como diana
|
|
JP2008524331A
(ja)
|
2004-12-21 |
2008-07-10 |
武田薬品工業株式会社 |
ジペプチジルペプチダーゼ阻害剤
|
|
WO2006130217A2
(en)
*
|
2005-04-01 |
2006-12-07 |
The Regents Of The University Of California |
Substituted phosphate esters of nucleoside phosphonates
|
|
US8222257B2
(en)
|
2005-04-01 |
2012-07-17 |
The Regents Of The University Of California |
Phosphono-pent-2-en-1-yl nucleosides and analogs
|
|
EP3081215B9
(en)
|
2005-05-23 |
2020-08-19 |
Natural Alternatives International, Inc. |
Compositions and methods for the sustained release of beta-alanine
|
|
EP1891067B1
(en)
*
|
2005-06-17 |
2016-01-13 |
Ligand Pharmaceuticals Incorporated |
Androgen receptor modulator compounds and methods
|
|
US20100098640A1
(en)
*
|
2005-06-20 |
2010-04-22 |
Cohen Seth M |
Multidentate Pyrone-Derived Chelators for Medicinal Imaging and Chelation
|
|
US20080058282A1
(en)
|
2005-08-30 |
2008-03-06 |
Fallon Joan M |
Use of lactulose in the treatment of autism
|
|
WO2008051197A2
(en)
*
|
2005-09-20 |
2008-05-02 |
Mayo Foundation For Medical Education And Research |
Small-molecule botulinum toxin inhibitors
|
|
US8119655B2
(en)
|
2005-10-07 |
2012-02-21 |
Takeda Pharmaceutical Company Limited |
Kinase inhibitors
|
|
US8138361B2
(en)
*
|
2005-12-28 |
2012-03-20 |
The Trustees Of The University Of Pennsylvania |
C-10 carbamates of taxanes
|
|
MX2008011844A
(es)
*
|
2006-03-13 |
2008-10-02 |
Encysive Pharmaceuticals Inc |
Formulaciones de sitaxsentano de sodio.
|
|
EP2013182B1
(en)
|
2006-03-13 |
2013-09-04 |
Kyorin Pharmaceutical Co., Ltd. |
Aminoquinolones as gsk-3 inhibitors
|
|
CN101404981A
(zh)
*
|
2006-03-13 |
2009-04-08 |
恩希赛弗制药公司 |
治疗舒张性心力衰竭的方法和组合物
|
|
CN101460161A
(zh)
*
|
2006-03-29 |
2009-06-17 |
弗尔德里克斯制药股份有限公司 |
α-突触核蛋白毒性的抑制
|
|
US20080026061A1
(en)
*
|
2006-06-22 |
2008-01-31 |
Reichwein John F |
Crystalline N-(4-chloro-3-methyl-5-isoxazolyl)-2-[2-methyl-4.5-(methylenedioxy)phenylacetyl]-thiophene-3-sulfonamide
|
|
TWI405771B
(zh)
|
2006-08-28 |
2013-08-21 |
Kyowa Hakko Kirin Co Ltd |
具拮抗性之人類light專一性人類單株抗體
|
|
PL2066662T3
(pl)
|
2006-09-21 |
2013-05-31 |
Kyorin Seiyaku Kk |
Inhibitory hydrolaz serynowych
|
|
EP2145878A3
(en)
|
2006-10-09 |
2010-02-24 |
Takeda Pharmaceutical Company Limited |
Aurora Kinase inhibitors
|
|
JP2010505961A
(ja)
|
2006-10-09 |
2010-02-25 |
タケダ サン ディエゴ インコーポレイテッド |
キナーゼ阻害剤
|
|
EP2617423A1
(en)
|
2006-10-19 |
2013-07-24 |
Genzyme Corporation |
Purine derivatives for the treatment of cystic diseases
|
|
CN101687788A
(zh)
|
2006-10-19 |
2010-03-31 |
奥斯拜客斯制药有限公司 |
取代的吲哚
|
|
WO2008055236A2
(en)
|
2006-10-31 |
2008-05-08 |
Takeda Pharmaceutical Company Limited |
Mapk/erk kinase inhibitors
|
|
US20100137421A1
(en)
*
|
2006-11-08 |
2010-06-03 |
Emmanuel Theodorakis |
Small molecule therapeutics, synthesis of analogues and derivatives and methods of use
|
|
CA2671766A1
(en)
*
|
2006-12-22 |
2008-07-03 |
Encysive Pharmaceuticals, Inc. |
Modulators of c3a receptor and methods of use thereof
|
|
PT2144604E
(pt)
*
|
2007-02-28 |
2011-10-19 |
Conatus Pharmaceuticals Inc |
Métodos para o tratamento da hepatite c viral crónica utilizando ro-113-0830
|
|
WO2008106167A1
(en)
*
|
2007-02-28 |
2008-09-04 |
Conatus Pharmaceuticals, Inc. |
Combination therapy comprising matrix metalloproteinase inhibitors and caspase inhibitors for the treatment of liver diseases
|
|
HRP20161581T1
(hr)
|
2007-03-15 |
2016-12-30 |
Auspex Pharmaceuticals, Inc. |
DEUTERIRANI d9-VENLAFAKSI
|
|
EP2170062A4
(en)
*
|
2007-07-12 |
2010-12-29 |
Tragara Pharmaceuticals Inc |
METHOD AND COMPOSITIONS FOR THE TREATMENT OF CANCER DISORDERS, TUMORS AND TUMOR-DISORDED DISEASES
|
|
MX2010002667A
(es)
*
|
2007-09-11 |
2010-04-01 |
Activx Biosciences Inc |
Cianoaminoquinolonas y tetrazoloaminoquinolonas como inhibidores de gsk-3.
|
|
CN101855229A
(zh)
|
2007-09-12 |
2010-10-06 |
埃迪威克斯生物科学公司 |
作为gsk-3抑制剂的螺环状氨基喹诺酮
|
|
WO2009042711A1
(en)
|
2007-09-25 |
2009-04-02 |
Takeda Pharmaceutical Company Limited |
Polo-like kinase inhibitors
|
|
US20090264421A1
(en)
*
|
2007-10-05 |
2009-10-22 |
Bible Keith C |
Methods and Compositions for Treating Cancer
|
|
PL2205244T3
(pl)
|
2007-11-08 |
2014-01-31 |
Ambit Biosciences Corp |
Sposoby podawania N-(5-tert-butylo-izoksazol-3-ilo)-N’-{4-[7-(2-morfolin-4-ylo-etoksy)-imidazo-[2,1-b]-[1,3]-benzotiazol-2-ilo]-fenylo} mocznika do leczenia chorób proliferacyjnych
|
|
AU2008327615B2
(en)
|
2007-11-21 |
2014-08-21 |
Pharmaxis Ltd. |
Haloallylamine inhibitors of SSAO/VAP-1 and uses therefor
|
|
CA2709677C
(en)
|
2007-12-21 |
2017-03-14 |
Lin Zhi |
Selective androgen receptor modulators (sarms) and uses thereof
|
|
US8658163B2
(en)
|
2008-03-13 |
2014-02-25 |
Curemark Llc |
Compositions and use thereof for treating symptoms of preeclampsia
|
|
KR101601997B1
(ko)
|
2008-03-17 |
2016-03-17 |
암비트 바이오사이언시즈 코포레이션 |
Raf 키나아제 조절제로서의 퀴나졸린 유도체 및 그의 사용방법
|
|
TW200946541A
(en)
*
|
2008-03-27 |
2009-11-16 |
Idenix Pharmaceuticals Inc |
Solid forms of an anti-HIV phosphoindole compound
|
|
US8084025B2
(en)
|
2008-04-18 |
2011-12-27 |
Curemark Llc |
Method for the treatment of the symptoms of drug and alcohol addiction
|
|
BRPI0912842A8
(pt)
*
|
2008-05-20 |
2019-01-29 |
Cerenis Therapeutics Holding |
composição farmacêutica, métodos para prevenir ou tratar o rubor induzido por niacina em um indivíduo, para reduzir pelo menos um sintoma de rubor relacionado com a terapia com niacina em um indivíduo, para diminuir os efeitos colaterais relacionados com a protaglandina em um indivíduo, para diminuir uma taxa de descontinuação do tratamento com niacina por um indivíduo, para aumentar a submissão do paciente ao tratamento com niacina, para tratar aterosclerose em um paciente, para tratar uma doença relacionada com um perfil de hdl baixo em um paciente, formulação do ácido nicotínico de dispensação modificada, uso da composição farmacêutica, e, microcápsula de aspirina
|
|
US20110178070A1
(en)
|
2008-06-24 |
2011-07-21 |
Takeda Pharmaceutical Company Limited |
PI3K/mTOR INHIBITORS
|
|
US11016104B2
(en)
|
2008-07-01 |
2021-05-25 |
Curemark, Llc |
Methods and compositions for the treatment of symptoms of neurological and mental health disorders
|
|
CA3050530A1
(en)
|
2009-01-06 |
2010-07-15 |
Galenagen, Llc |
Compositions and methods for the treatment or prevention of staphylococcus aureus infections and for the eradication or reduction of staphylococcus aureus on surfaces
|
|
GB2480773B
(en)
|
2009-01-06 |
2013-12-11 |
Curelon Llc |
Compositions for the treatment of diarrhea caused by virulent E. coli infections
|
|
WO2010088450A2
(en)
|
2009-01-30 |
2010-08-05 |
Celladon Corporation |
Methods for treating diseases associated with the modulation of serca
|
|
US8568793B2
(en)
|
2009-02-11 |
2013-10-29 |
Hope Medical Enterprises, Inc. |
Sodium nitrite-containing pharmaceutical compositions
|
|
EP2401267B1
(en)
|
2009-02-27 |
2014-01-15 |
Ambit Biosciences Corporation |
Jak kinase modulating quinazoline derivatives and their use in methods
|
|
WO2010101967A2
(en)
|
2009-03-04 |
2010-09-10 |
Idenix Pharmaceuticals, Inc. |
Phosphothiophene and phosphothiazole hcv polymerase inhibitors
|
|
WO2010105016A1
(en)
|
2009-03-11 |
2010-09-16 |
Ambit Biosciences Corp. |
Combination of an indazolylaminopyrrolotriazine and taxane for cancer treatment
|
|
AU2010228982B2
(en)
|
2009-03-23 |
2015-05-14 |
Ambit Biosciences Corporation |
Methods of treatment using combination therapy
|
|
WO2010110686A1
(en)
|
2009-03-27 |
2010-09-30 |
Pathway Therapeutics Limited |
Pyrimidinyl and 1,3,5 triazinyl benzimidazoles and their use in cancer therapy
|
|
US8669249B2
(en)
|
2009-03-27 |
2014-03-11 |
Takeda Pharmaceutical Company Limited |
Poly (ADP-ribose) polymerase (PARP) inhibitors
|
|
TW201038567A
(en)
|
2009-03-27 |
2010-11-01 |
Pathway Therapeutics Ltd |
Pyrimidinyl and 1,3,5-triazinyl benzimidazole sulfonamides and their use in cancer therapy
|
|
US9056050B2
(en)
|
2009-04-13 |
2015-06-16 |
Curemark Llc |
Enzyme delivery systems and methods of preparation and use
|
|
SG2014005110A
(en)
|
2009-04-22 |
2014-03-28 |
Axikin Pharmaceuticals Inc |
Arylsulfonamide ccr3 antagonists
|
|
JP2012524789A
(ja)
|
2009-04-22 |
2012-10-18 |
アクシキン ファーマシューティカルズ インコーポレーテッド |
2,5−二置換アリールスルホンアミドccr3アンタゴニスト
|
|
KR101687144B1
(ko)
|
2009-04-22 |
2016-12-15 |
액시킨 파마수티컬스 인코포레이티드 |
2,5-이치환된 아릴설폰아마이드 ccr3 길항제
|
|
SMT202000092T1
(it)
|
2009-05-14 |
2020-05-08 |
Ambit Biosciences Corp |
Formulazione essiccata a spruzzo o liofilizzata di ac220
|
|
AR080945A1
(es)
|
2009-07-07 |
2012-05-23 |
Pathway Therapeutics Inc |
Pirimidinil y 1,3,5-triazinil benzimidazoles y su uso en la terapia contra el cancer
|
|
CA2767168C
(en)
|
2009-07-08 |
2019-04-09 |
Hope Medical Enterprises, Inc. D.B.A. Hope Pharmaceuticals |
Sodium thiosulfate-containing pharmaceutical compositions
|
|
US8404728B2
(en)
|
2009-07-30 |
2013-03-26 |
Mayo Foundation For Medical Education And Research |
Small-molecule botulinum toxin inhibitors
|
|
WO2011014681A1
(en)
|
2009-07-30 |
2011-02-03 |
Takeda Pharmaceutical Company Limited |
Poly (ADP-Ribose) Polymerase (PARP) INHIBITORS
|
|
US9284307B2
(en)
|
2009-08-05 |
2016-03-15 |
Idenix Pharmaceuticals Llc |
Macrocyclic serine protease inhibitors
|
|
RU2012109545A
(ru)
|
2009-08-14 |
2013-09-20 |
Серенис Терапьютикс С.А. |
Использование лигандов ppar дельта для лечения или предотвращения воспалений или заболеваний, связанных с метаболизмом/выработкой энергии
|
|
WO2011041293A1
(en)
|
2009-09-30 |
2011-04-07 |
Takeda Pharmaceutical Company Limited |
Pyrazolo [1, 5-a] pyrimidine derivatives as apoptosis signal-regulating kinase 1 inhibitors
|
|
WO2011056566A2
(en)
|
2009-10-26 |
2011-05-12 |
Sunesis Pharmaceuticals, Inc. |
Compounds and methods for treatment of cancer
|
|
WO2011054087A1
(en)
*
|
2009-11-03 |
2011-05-12 |
Bernard Charles Sherman |
Stable pharmaceutical formulations comprising lubiprostone
|
|
WO2011056764A1
(en)
|
2009-11-05 |
2011-05-12 |
Ambit Biosciences Corp. |
Isotopically enriched or fluorinated imidazo[2,1-b][1,3]benzothiazoles
|
|
WO2011057214A2
(en)
|
2009-11-09 |
2011-05-12 |
Neurogenetic Pharmaceuticals, Inc. |
Gamma-secretase modulatory compounds, methods for identifying same, and uses therefor
|
|
WO2011069002A1
(en)
|
2009-12-02 |
2011-06-09 |
Alquest Therapeutics, Inc. |
Organoselenium compounds and uses thereof
|
|
CA2784748A1
(en)
|
2009-12-18 |
2011-06-23 |
Idenix Pharmaceuticals, Inc. |
5,5-fused arylene or heteroarylene hepatitis c virus inhibitors
|
|
SG181896A1
(en)
*
|
2009-12-23 |
2012-07-30 |
Map Pharmaceuticals Inc |
Novel ergoline analogs
|
|
EP2521721B1
(en)
*
|
2009-12-30 |
2014-10-01 |
Shanghai Fochon Pharmaceutical Co. Ltd |
3-(3-aminopiperidin-1-yl)-5-oxo-1,2,4-triazine derivates as dipeptidyl peptidase iv(dpp-iv) inhibitors
|
|
US8802695B2
(en)
|
2010-02-03 |
2014-08-12 |
Takeda Pharmaceutical Company Limited |
Apoptosis signal-regulating kinase 1 inhibitors
|
|
CA2791964A1
(en)
|
2010-03-02 |
2011-09-09 |
Axikin Pharmaceuticals, Inc. |
Isotopically enriched arylsulfonamide ccr3 antagonists
|
|
WO2011112689A2
(en)
|
2010-03-11 |
2011-09-15 |
Ambit Biosciences Corp. |
Saltz of an indazolylpyrrolotriazine
|
|
MX336559B
(es)
|
2010-03-17 |
2016-01-25 |
Axikin Pharmaceuticals Inc |
Antagonistas de ccr3 de arilsulfonamida.
|
|
JP5937060B2
(ja)
|
2010-04-07 |
2016-06-22 |
セルジーン コーポレイション |
呼吸器ウイルス感染症の治療方法
|
|
MX2012013879A
(es)
|
2010-06-01 |
2013-04-03 |
Biotheryx Inc |
Derivados de hidroxipiridona, composiciones farmceuticas de los mismos y su uso terapeutico para tratar enfermedades proliferativas.
|
|
AU2011261501B2
(en)
|
2010-06-01 |
2016-01-21 |
Biotheryx, Inc. |
Methods of treating hematologic malignancies using 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone
|
|
JP5855095B2
(ja)
|
2010-06-07 |
2016-02-09 |
ノボメディックス, エルエルシーNovomedix, Llc |
フラニル化合物およびその使用
|
|
JP6069661B2
(ja)
|
2010-06-24 |
2017-02-01 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
種々のアミロイドβペプチドアロフォームレベルの調節における組成物及びその使用
|
|
NZ605860A
(en)
|
2010-07-19 |
2015-04-24 |
Summa Health System |
Use of vitamin c, and chromium-free vitamin k or 2-methyl-1,4-naphthalendione, and compositions thereof for treating a polycystic disease
|
|
WO2012030924A1
(en)
|
2010-09-01 |
2012-03-08 |
Ambit Biosciences Corporation |
Azolopyridine and azolopyrimidine compounds and methods of use thereof
|
|
US8703943B2
(en)
|
2010-09-01 |
2014-04-22 |
Ambit Biosciences Corporation |
Optically active pyrazolylaminoquinazoline, and pharmaceutical compositions and methods of use thereof
|
|
US20130225614A1
(en)
|
2010-09-01 |
2013-08-29 |
Ambit Biosciences Corporation |
4-azolylaminoquinazoline derivatives and methods of use thereof
|
|
AU2011296024B2
(en)
|
2010-09-01 |
2015-05-28 |
Ambit Biosciences Corporation |
Quinazoline compounds and methods of use thereof
|
|
US20130317045A1
(en)
|
2010-09-01 |
2013-11-28 |
Ambit Biosciences Corporation |
Thienopyridine and thienopyrimidine compounds and methods of use thereof
|
|
US20120053176A1
(en)
|
2010-09-01 |
2012-03-01 |
Ambit Biosciences Corp. |
Adenosine a3 receptor modulating compounds and methods of use thereof
|
|
US20130296363A1
(en)
|
2010-09-01 |
2013-11-07 |
Ambit Biosciences Corporation |
Quinoline and isoquinoline derivatives for use as jak modulators
|
|
MX2013002383A
(es)
|
2010-09-01 |
2013-07-05 |
Ambit Biosciences Corp |
Sales bromhidrato de una pirazolilaminoquinazolina.
|
|
WO2012030912A1
(en)
|
2010-09-01 |
2012-03-08 |
Ambit Biosciences Corporation |
7-cyclylquinazoline derivatives and methods of use thereof
|
|
US20130225615A1
(en)
|
2010-09-01 |
2013-08-29 |
Ambit Biosciences Corporation |
2-cycloquinazoline derivatives and methods of use thereof
|
|
US8859502B2
(en)
|
2010-09-13 |
2014-10-14 |
Celgene Corporation |
Therapy for MLL-rearranged leukemia
|
|
WO2012044641A1
(en)
|
2010-09-29 |
2012-04-05 |
Pathway Therapeutics Inc. |
1,3,5-triazinyl benzimidazole sulfonamides and their use in cancer therapy
|
|
CA2814011A1
(en)
|
2010-10-11 |
2012-04-19 |
Axikin Pharmaceuticals, Inc. |
Salts of arylsulfonamide ccr3 antagonists
|
|
WO2012080050A1
(en)
|
2010-12-14 |
2012-06-21 |
F. Hoffmann-La Roche Ag |
Solid forms of a phenoxybenzenesulfonyl compound
|
|
TW201309690A
(zh)
|
2011-02-10 |
2013-03-01 |
Idenix Pharmaceuticals Inc |
巨環絲胺酸蛋白酶抑制劑,其醫藥組合物及其於治療hcv感染之用途
|
|
WO2012135166A1
(en)
|
2011-03-28 |
2012-10-04 |
Pathway Therapeutics Inc. |
(fused ring arylamino and heterocyclylamino) pyrimidynyl and 1,3,5-triazinyl benzimidazoles, pharmaceutical compositions thereof, and their use in treating proliferative diseases
|
|
WO2012135175A1
(en)
|
2011-03-28 |
2012-10-04 |
Pathway Therapeutics Inc. |
(alpha-substituted cycloalkylamino and heterocyclylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, pharmaceutical compositions thereof, and their use in treating proliferative diseases
|
|
KR101940831B1
(ko)
|
2011-03-28 |
2019-01-21 |
메이 파마, 아이엔씨. |
(알파-치환된 아르알킬아미노 및 헤테로아릴알킬아미노)피리미딘일 및 1,3,5-트라이아진일 벤즈이미다졸, 이들을 함유하는 약학 조성물, 및 증식성 질병의 치료에 사용하기 위한 이들 화합물
|
|
US20120252721A1
(en)
|
2011-03-31 |
2012-10-04 |
Idenix Pharmaceuticals, Inc. |
Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
|
|
GB2503852B
(en)
|
2011-04-21 |
2018-12-12 |
Curemark Llc |
Compounds for the treatment of neuropsychiatric disorders
|
|
WO2012177962A1
(en)
|
2011-06-23 |
2012-12-27 |
Map Pharmaceuticals, Inc. |
Novel fluoroergoline analogs
|
|
WO2013022872A1
(en)
|
2011-08-10 |
2013-02-14 |
Celgene Corporation |
Gene methylation biomarkers and methods of use thereof
|
|
WO2013033656A1
(en)
|
2011-09-02 |
2013-03-07 |
Syndax Pharmaceuticals, Inc. |
Methods for the treatment of breast cancer
|
|
WO2013037482A1
(en)
|
2011-09-15 |
2013-03-21 |
Phenex Pharmaceuticals Ag |
Farnesoid x receptor agonists for cancer treatment and prevention
|
|
CA2849708A1
(en)
|
2011-09-23 |
2013-03-28 |
Celgene Corporation |
Romidepsin and 5 - azacitidine for use in treating lymphoma
|
|
EP2760456A1
(en)
|
2011-09-26 |
2014-08-06 |
Celgene Corporation |
Combination therapy for chemoresistant cancers
|
|
PH12014500965A1
(en)
|
2011-11-01 |
2014-06-30 |
Celgene Corp |
Methods for treating cancers using oral formulations of cytidine analogs
|
|
WO2013085902A1
(en)
|
2011-12-05 |
2013-06-13 |
The University Of Texas M.D. |
Combination therapy methods for treating an inflammatory breast cancer
|
|
AU2012355982A1
(en)
|
2011-12-19 |
2014-07-10 |
Map Pharmaceuticals, Inc. |
Novel iso-ergoline derivatives
|
|
WO2013095708A1
(en)
|
2011-12-21 |
2013-06-27 |
Map Pharmaceuticals, Inc. |
Novel neuromodulatory compounds
|
|
US9611253B2
(en)
|
2012-02-29 |
2017-04-04 |
Ambit Biosciences Corporation |
Solid forms comprising optically active pyrazolylaminoquinazoline, compositions thereof, and uses therewith
|
|
WO2013134047A2
(en)
|
2012-03-07 |
2013-09-12 |
The Mclean Hospital Corporation |
Aminoquinoline derivatives and uses thereof
|
|
JP6134376B2
(ja)
|
2012-03-16 |
2017-05-24 |
アクシキン ファーマシューティカルズ インコーポレーテッド |
3,5−ジアミノピラゾールキナーゼ阻害剤
|
|
WO2013148919A1
(en)
|
2012-03-30 |
2013-10-03 |
The Regents Of The University Of Colorado, A Body Corporate |
Treatment of multiple myeloma
|
|
PL2844637T3
(pl)
|
2012-05-02 |
2018-09-28 |
Boehringer Ingelheim International Gmbh |
Podstawione 3-haloalliloaminowe inhibitory ssao i ich zastosowania
|
|
US10350278B2
(en)
|
2012-05-30 |
2019-07-16 |
Curemark, Llc |
Methods of treating Celiac disease
|
|
WO2013187965A1
(en)
|
2012-06-14 |
2013-12-19 |
Mayo Foundation For Medical Education And Research |
Pyrazole derivatives as inhibitors of stat3
|
|
US9012640B2
(en)
|
2012-06-22 |
2015-04-21 |
Map Pharmaceuticals, Inc. |
Cabergoline derivatives
|
|
US8551535B1
(en)
|
2012-08-06 |
2013-10-08 |
Sarah McCann |
Homeopathic remedies and methods for enhancing weight loss
|
|
US9074186B2
(en)
|
2012-08-15 |
2015-07-07 |
Boston Medical Center Corporation |
Production of red blood cells and platelets from stem cells
|
|
JP2015527396A
(ja)
|
2012-09-07 |
2015-09-17 |
アクシキン ファーマシューティカルズ インコーポレーテッド |
同位体濃縮されたアリールスルホンアミドccr3アンタゴニスト
|
|
AU2013202506B2
(en)
|
2012-09-07 |
2015-06-18 |
Celgene Corporation |
Resistance biomarkers for hdac inhibitors
|
|
WO2014055647A1
(en)
|
2012-10-03 |
2014-04-10 |
Mei Pharma, Inc. |
(sulfinyl and sulfonyl benzimidazolyl) pyrimidines and triazines, pharmaceutical compositions thereof, and their use for treating proliferative diseases
|
|
CA2890177A1
(en)
|
2012-11-08 |
2014-05-15 |
Summa Health System |
Vitamin c, vitamin k, a polyphenol, and combinations thereof for wound healing
|
|
AU2013202507B9
(en)
|
2012-11-14 |
2015-08-13 |
Celgene Corporation |
Inhibition of drug resistant cancer cells
|
|
WO2014085633A1
(en)
|
2012-11-30 |
2014-06-05 |
Novomedix, Llc |
Substituted biaryl sulfonamides and the use thereof
|
|
BR112015014964A2
(pt)
|
2012-12-21 |
2017-07-11 |
Map Pharmaceuticals Inc |
novos derivados de metisergida
|
|
US9169214B2
(en)
|
2012-12-21 |
2015-10-27 |
The Board Of Trustees Of The Leland Stanford Junior University |
Compounds and compositions that bind and stabilize transthyretin and their use for inhibiting transthyretin amyloidosis and protein-protein interactions
|
|
AU2014205324A1
(en)
|
2013-01-11 |
2015-07-30 |
Mayo Foundation For Medical Education And Research |
Vitamins C and K for treating polycystic diseases
|
|
WO2014130908A1
(en)
|
2013-02-22 |
2014-08-28 |
University Of Southern California |
Methods for treatment of ophthalmic diseases and disorders
|
|
US9938263B2
(en)
|
2013-03-12 |
2018-04-10 |
The General Hospital Corporation |
Gamma-secretase modulators
|
|
NZ712479A
(en)
|
2013-03-15 |
2019-01-25 |
Univ Southern California |
Methods, compounds, and compositions for the treatment of angiotensin-related diseases
|
|
US9629860B2
(en)
|
2013-03-15 |
2017-04-25 |
The Regents Of The University Of California |
Acyclic nucleoside phosphonate diesters
|
|
WO2014160698A1
(en)
|
2013-03-26 |
2014-10-02 |
Celgene Corporation |
SOLID FORMS COMPRISING 4-AMINO-I-β-D-RIBOFURANOSYL-1,3,5-TRIAZIN-2(1H)-ONE AND A COFORMER, COMPOSITIONS AND METHODS OF USE THEREOF
|
|
CA2914369C
(en)
|
2013-06-06 |
2023-02-14 |
Igenica Biotherapeutics, Inc. |
Anti-c10orf54 antibodies and uses thereof
|
|
EP2815749A1
(en)
|
2013-06-20 |
2014-12-24 |
IP Gesellschaft für Management mbH |
Solid form of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione having specified X-ray diffraction pattern
|
|
NZ631142A
(en)
|
2013-09-18 |
2016-03-31 |
Axikin Pharmaceuticals Inc |
Pharmaceutically acceptable salts of 3,5-diaminopyrazole kinase inhibitors
|
|
WO2015042375A1
(en)
|
2013-09-20 |
2015-03-26 |
Idenix Pharmaceuticals, Inc. |
Hepatitis c virus inhibitors
|
|
US9700549B2
(en)
|
2013-10-03 |
2017-07-11 |
David Wise |
Compositions and methods for treating pelvic pain and other conditions
|
|
US9714232B2
(en)
|
2013-12-20 |
2017-07-25 |
Sunshine Lake Pharma Co., Ltd. |
Substituted piperazine compounds and methods of use thereof
|
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
|
EP3114122A1
(en)
|
2014-03-05 |
2017-01-11 |
Idenix Pharmaceuticals LLC |
Solid forms of a flaviviridae virus inhibitor compound and salts thereof
|
|
KR20240064750A
(ko)
|
2014-03-20 |
2024-05-13 |
카펠라 테라퓨틱스, 인크. |
암 치료용의 erbb 티로신 키나제 억제제로서의 벤즈이미다졸 유도체
|
|
JP6568926B2
(ja)
|
2014-03-20 |
2019-08-28 |
カペラ セラピューティクス,インコーポレーテッド |
癌の治療のためのerbbチロシンキナーゼ阻害剤としてのベンゾイミダゾール誘導体
|
|
EP3122728A4
(en)
|
2014-03-28 |
2017-10-25 |
Calitor Sciences, LLC |
Substituted heteroaryl compounds and methods of use
|
|
EP3444011A1
(en)
|
2014-05-12 |
2019-02-20 |
Conatus Pharmaceuticals, Inc. |
Treatment of the complications of chronic liver disease with emricasan
|
|
WO2015195786A2
(en)
|
2014-06-17 |
2015-12-23 |
Celgene Corporation |
Methods for treating cancers using oral formulations of cytidine analogs
|
|
WO2015195634A1
(en)
|
2014-06-17 |
2015-12-23 |
Celgne Corporation |
Methods for treating epstein-barr virus (ebv) associated cancers using oral formulations of 5-azacytidine
|
|
WO2015195474A1
(en)
|
2014-06-18 |
2015-12-23 |
Biotheryx, Inc. |
Hydroxypyridone derivatives, pharmaceutical compositions thereof, and their therapeutic use for treating inflammatory, neurodegenerative, or immune-mediated diseases
|
|
US9499514B2
(en)
|
2014-07-11 |
2016-11-22 |
Celgene Corporation |
Antiproliferative compounds and methods of use thereof
|
|
JP6543342B2
(ja)
|
2014-08-14 |
2019-07-10 |
アルハマドシャー,マモウン,エム. |
血清半減期を延長するための、調節可能リンカーを介した薬学的活性剤とトランスサイレチンリガンドのコンジュゲーション
|
|
WO2016044281A1
(en)
|
2014-09-15 |
2016-03-24 |
The Regents Of The University Of California |
Nucleotide analogs
|
|
US20170354639A1
(en)
|
2014-10-24 |
2017-12-14 |
Biogen Ma Inc. |
Diterpenoid derivatives and methods of use thereof
|
|
MX381224B
(es)
|
2014-10-31 |
2025-03-12 |
Massachusetts Gen Hospital |
Potentes moduladores de gamma-secretasa.
|
|
KR102693806B1
(ko)
|
2014-12-11 |
2024-08-09 |
피에르 파브르 메디카먼트 |
항-c10orf54 항체들 및 그들의 용도들
|
|
MY191736A
(en)
|
2014-12-23 |
2022-07-13 |
Axikin Pharmaceuticals Inc |
3,5-diaminopyrazole kinase inhibitors
|
|
BR112017015487A2
(pt)
|
2015-01-20 |
2018-01-30 |
Xoc Pharmaceuticals Inc |
Composto; composição; método de tratamento e/ou prevenção de enxaqueca, als, doença de alzheimer, doença de parkinson, distúrbios extrapirimidais, depressão, náusea, êmese, síndrome das pernas inquietas, insônia, agressão, doença de huntington, doença cardiopulmonar, fibrogênese, hipertensão arterial pulmonar, ansiedade, dependências a drogas, distonia, parassonia ou hiperlactinemia em um indivíduo; métodos de agonização dos receptores d2, 5-ht1d, 5-ht1a e 5-ht2c, em um indivíduo; método de antagonização do receptor d3 em um indivíduo; métodos de agonização seletiva dos receptores 5 -ht1d, e 5-ht2c, método de fornecimento de atividade de antagonista funcional no receptor 5 -ht2b ou no receptor 5-ht7, ou em ambos, em um indivíduo; método de fornecimento de atividade de antagonista funcional nos receptores adrenérgicos em um indivíduo
|
|
CN107405346A
(zh)
|
2015-01-20 |
2017-11-28 |
Xoc制药股份有限公司 |
异麦角灵化合物及其用途
|
|
LT3265123T
(lt)
|
2015-03-03 |
2023-01-25 |
Kymab Limited |
Antikūnai, naudojimas ir būdai
|
|
IL307850A
(en)
|
2015-03-20 |
2023-12-01 |
Syndax Pharmaceuticals Inc |
A combination of a histone deacetylase inhibitor and an antibody against programmed cell death protein 1 for the treatment of cancer
|
|
EP3289104B1
(en)
|
2015-04-29 |
2020-11-04 |
New York University |
Method for treating high-grade gliomas
|
|
CN107921032B
(zh)
|
2015-06-23 |
2021-09-24 |
纽罗克里生物科学有限公司 |
用于治疗神经学疾病或病症的vmat2抑制剂
|
|
EP3277842B9
(en)
|
2015-08-17 |
2020-01-15 |
Kura Oncology, Inc. |
Methods of treating cancer patients with farnesyl transferase inhibitors
|
|
CA2994731C
(en)
|
2015-09-02 |
2023-09-26 |
Syndax Pharmaceuticals, Inc. |
Selection of patients for combination therapy
|
|
EP3347097B1
(en)
|
2015-09-11 |
2021-02-24 |
Sunshine Lake Pharma Co., Ltd. |
Substituted aminopyrimidine derivatives as modulators of the kinases jak, flt3 and aurora
|
|
EP3350191B9
(en)
|
2015-09-15 |
2021-12-22 |
The Regents of the University of California |
Nucleotide analogs
|
|
EP3353214B1
(en)
|
2015-09-25 |
2021-08-18 |
Universität Duisburg-Essen |
Agents inhibiting kallikrein-8 for use in the prevention or treatment of alzheimer's disease
|
|
JP7109360B2
(ja)
|
2015-10-30 |
2022-07-29 |
ニューロクライン バイオサイエンシーズ,インコーポレイテッド |
バルベナジン塩およびその多形体
|
|
WO2017079566A1
(en)
|
2015-11-05 |
2017-05-11 |
Conatus Pharmaceuticals, Inc. |
Caspase inhibitors for use in the treatment of liver cancer
|
|
US10112924B2
(en)
|
2015-12-02 |
2018-10-30 |
Astraea Therapeutics, Inc. |
Piperdinyl nociceptin receptor compounds
|
|
CN108883103A
(zh)
|
2015-12-02 |
2018-11-23 |
阿斯特来亚治疗有限责任公司 |
哌啶基痛敏肽受体化合物
|
|
CA3009169A1
(en)
|
2015-12-23 |
2017-06-29 |
Neurocrine Biosciences, Inc. |
Synthetic methods for preparation of (s)-(2r,3r,11br)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1h-pyrido[2,1-a]isoquinolin-2-yl 2-amino-3-methylbutanoate di(4-methylbenzenesulfonate)
|
|
KR20180101418A
(ko)
|
2015-12-31 |
2018-09-12 |
코나터스 파마슈티칼스, 인크. |
간 질환의 치료에서의 카스파제 억제제의 사용 방법
|
|
EP3808346B1
(en)
|
2016-01-08 |
2023-07-19 |
Celgene Corporation |
Antiproliferative compounds for use in the treatment of leukemia
|
|
US10960013B2
(en)
|
2016-03-04 |
2021-03-30 |
East Carolina University |
J-series prostaglandin-ethanolamides as novel therapeutics for skin and/or oral disorders
|
|
JP2019513151A
(ja)
|
2016-03-08 |
2019-05-23 |
ロス ガトス ファーマスーティカルズ, インク.Los Gatos Pharmaceuticals, Inc. |
カンプトテシン誘導体及びその使用
|
|
JP2019510085A
(ja)
|
2016-03-08 |
2019-04-11 |
ロス ガトス ファーマスーティカルズ, インク.Los Gatos Pharmaceuticals, Inc. |
癌治療のためのナノ粒子ならびに方法および化合物
|
|
CN108884019A
(zh)
|
2016-04-11 |
2018-11-23 |
克雷西奥生物科技有限公司 |
氘代氯胺酮衍生物
|
|
US10047077B2
(en)
|
2016-04-13 |
2018-08-14 |
Skyline Antiinfectives, Inc. |
Deuterated O-sulfated beta-lactam hydroxamic acids and deuterated N-sulfated beta-lactams
|
|
US20190119758A1
(en)
|
2016-04-22 |
2019-04-25 |
Kura Oncology, Inc. |
Methods of selecting cancer patients for treatment with farnesyltransferase inhibitors
|
|
EP4190357A1
(en)
|
2016-05-13 |
2023-06-07 |
Institut Pasteur |
Inhibition of beta-2 nicotinic acetylcholine receptors to treat alzheimer's disease pathology
|
|
TWI753910B
(zh)
|
2016-05-16 |
2022-02-01 |
美商拜歐斯瑞克斯公司 |
吡啶硫酮、其醫藥組合物及其治療增生性、炎性、神經退化性或免疫介導疾病之治療用途
|
|
WO2018013689A1
(en)
|
2016-07-13 |
2018-01-18 |
Celgene Corporation |
Solid dispersions and solid forms comprising 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione, method of preparation and use thereof
|
|
WO2018013693A1
(en)
|
2016-07-13 |
2018-01-18 |
Celgene Corporation |
Solid dispersions and cocrystals comprising 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione compositions and methods of use thereof
|
|
US10919904B2
(en)
|
2016-08-17 |
2021-02-16 |
North Carolina State University |
Northern-southern route to synthesis of bacteriochlorins
|
|
US20190201409A1
(en)
|
2016-09-19 |
2019-07-04 |
Mei Pharma, Inc. |
Combination therapy
|
|
EP3534947A1
(en)
|
2016-11-03 |
2019-09-11 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses & methods
|
|
PT3534885T
(pt)
|
2016-11-03 |
2021-04-13 |
Kura Oncology Inc |
Inibidores de farnesiltransferase para usar em métodos de tratamento do cancro
|
|
CN110167542A
(zh)
|
2016-11-09 |
2019-08-23 |
诺沃梅迪科斯有限公司 |
1,1-二甲双胍的亚硝酸盐、药物组合物和使用方法
|
|
WO2018089692A1
(en)
|
2016-11-09 |
2018-05-17 |
Phloronol, Inc. |
Eckol derivatives, methods of synthesis and uses thereof
|
|
WO2018102252A1
(en)
|
2016-11-30 |
2018-06-07 |
North Carolina State University |
Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds
|
|
US10799503B2
(en)
|
2016-12-01 |
2020-10-13 |
Ignyta, Inc. |
Methods for the treatment of cancer
|
|
JP2020500875A
(ja)
|
2016-12-02 |
2020-01-16 |
ニューロクライン バイオサイエンシーズ,インコーポレイテッド |
統合失調症または統合失調感情障害を処置するためのバルベナジンの使用
|
|
EA201991782A1
(ru)
|
2017-01-27 |
2021-09-23 |
Нейрокрин Байосайенсиз, Инк. |
Способы введения некоторых vmat2-ингибиторов
|
|
JP7159174B2
(ja)
|
2017-02-02 |
2022-10-24 |
マックマスター、ユニバーシティー |
抗菌剤用増強剤としての重炭酸塩
|
|
MX2021015220A
(es)
|
2017-02-17 |
2022-12-01 |
Eidos Therapeutics Inc |
Procesos para preparar ácido 3-(3-(3,5-dimetil-1h-pirazol-4-il)pro poxi)-4- 5-fluorobenzoico (ag-10), sus compuestos intermedios, y sales del mismo.
|
|
EP3542800B1
(en)
|
2017-02-21 |
2022-06-01 |
Kura Oncology, Inc. |
Methods of treating cancer with farnesyltransferase inhibitors
|
|
US9956215B1
(en)
|
2017-02-21 |
2018-05-01 |
Kura Oncology, Inc. |
Methods of treating cancer with farnesyltransferase inhibitors
|
|
WO2018164996A1
(en)
|
2017-03-06 |
2018-09-13 |
Neurocrine Biosciences, Inc. |
Dosing regimen for valbenazine
|
|
BR112019020464A2
(pt)
|
2017-03-30 |
2020-04-28 |
Xw Laboratories Inc. |
compostos derivados de heteroarila bicíclica, composição farmacêutica compreendendo os ditos compostos, adesivo transdérmico compreendendo a dita composição e uso terapêutico dos compostos e composição
|
|
EP3609528A4
(en)
|
2017-04-10 |
2020-12-23 |
Curemark, LLC |
COMPOSITIONS FOR THE TREATMENT OF ADDICTION
|
|
JP6963164B2
(ja)
|
2017-04-24 |
2021-11-05 |
チンワー ユニバーシティー |
アポトーシス誘導及び抗感染治療における自己誘導物質関連経路の応用
|
|
WO2018200605A1
(en)
|
2017-04-26 |
2018-11-01 |
Neurocrine Biosciences, Inc. |
Use of valbenazine for treating levodopa-induced dyskinesia
|
|
JOP20190219A1
(ar)
|
2017-05-09 |
2019-09-22 |
Cardix Therapeutics LLC |
تركيبات صيدلانية وطرق لعلاج أمراض القلب والأوعية الدموية
|
|
US10085999B1
(en)
|
2017-05-10 |
2018-10-02 |
Arixa Pharmaceuticals, Inc. |
Beta-lactamase inhibitors and uses thereof
|
|
WO2018223065A1
(en)
|
2017-06-01 |
2018-12-06 |
Xoc Pharmaceuticals, Inc. |
Ergoline derivatives for use in medicine
|
|
WO2019002228A1
(en)
|
2017-06-26 |
2019-01-03 |
Institut Pasteur |
TREATMENTS TO REMOVE HIV RESERVOIRS AND REDUCE VIRAL LOAD
|
|
US10806730B2
(en)
|
2017-08-07 |
2020-10-20 |
Kura Oncology, Inc. |
Methods of treating cancer with farnesyltransferase inhibitors
|
|
TW201919628A
(zh)
|
2017-08-07 |
2019-06-01 |
美商庫拉腫瘤技術股份有限公司 |
以法尼基轉移酶(farnesyltransferase)抑制劑治療癌症之方法
|
|
JP7069295B2
(ja)
|
2017-08-17 |
2022-05-17 |
エックスダブリューファルマ リミテッド |
活性酸素種スカベンジャー誘導体の調製および使用
|
|
EP4265257A1
(en)
|
2017-09-01 |
2023-10-25 |
East Carolina University |
Combination of a j-series prostaglandin-ethanolamide and a checkpoint inhibitor for use in treating cancer
|
|
ES2909718T3
(es)
|
2017-09-04 |
2022-05-10 |
Xwpharma Ltd |
Preparación y uso de un barredor de especies reactivas de oxígeno
|
|
CN111372567B
(zh)
|
2017-09-21 |
2024-03-15 |
纽罗克里生物科学有限公司 |
高剂量的缬苯那嗪制剂和与其相关的组合物、方法和试剂盒
|
|
KR20200084864A
(ko)
|
2017-10-04 |
2020-07-13 |
더 리젠츠 오브 더 유니버시티 오브 캘리포니아 |
면역조절성 올리고사카라이드
|
|
WO2019074492A1
(en)
|
2017-10-10 |
2019-04-18 |
Obrien Christopher F |
METHODS OF ADMINISTRATION OF CERTAIN VMAT2 INHIBITORS
|
|
KR20250070134A
(ko)
|
2017-10-10 |
2025-05-20 |
뉴로크린 바이오사이언시즈 인코퍼레이티드 |
특정 vmat2 억제제의 투여 방법
|
|
US20190216751A1
(en)
|
2017-11-15 |
2019-07-18 |
California State University Northridge |
Compositions and Methods for the Treatment and Prevention of Cancer
|
|
WO2019099311A1
(en)
|
2017-11-19 |
2019-05-23 |
Sunshine Lake Pharma Co., Ltd. |
Substituted heteroaryl compounds and methods of use
|
|
WO2019113269A1
(en)
|
2017-12-08 |
2019-06-13 |
Kura Oncology, Inc. |
Methods of treating cancer patients with farnesyltransferase inhibitors
|
|
JP7167168B2
(ja)
|
2018-01-10 |
2022-11-08 |
エックスダブリューファルマ リミテッド |
ケタミンのプロドラッグ、組成物及びそれらの使用
|
|
US11701334B2
(en)
|
2018-01-10 |
2023-07-18 |
Cura Therapeutics, Llc |
Pharmaceutical compositions comprising phenylsulfonamides, and their therapeutic applications
|
|
WO2019139871A1
(en)
|
2018-01-10 |
2019-07-18 |
Cura Therapeutics Llc |
Pharmaceutical compositions comprising dicarboxylic acids and their therapeutic applications
|
|
EP3749666A1
(en)
|
2018-02-08 |
2020-12-16 |
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. |
Heteroaryl compounds, pharmaceutical compositions thereof, and their therapeutic use
|
|
UA130053C2
(uk)
|
2018-03-23 |
2025-10-29 |
Ейдос Терапьютікс, Інк. |
Спосіб лікування транстиретинового амілоїдозу із застосуванням ag10
|
|
EP4438124A3
(en)
|
2018-04-27 |
2024-12-18 |
Spruce Biosciences, Inc. |
Methods for treating testicular and ovarian adrenal rest tumors
|
|
WO2019217484A1
(en)
|
2018-05-07 |
2019-11-14 |
Syndax Pharmaceuticals, Inc. |
Selection of patients for combination therapy
|
|
WO2019232724A1
(en)
|
2018-06-06 |
2019-12-12 |
Xw Laboratories, Inc. |
Compounds as nuclear transport modulators and uses thereof
|
|
MX2020013004A
(es)
|
2018-06-14 |
2021-02-17 |
Neurocrine Biosciences Inc |
Compuestos inhibidores del transportador de monoamina 2 (vmat2), composiciones, y metodos relacionados con los mismos.
|
|
WO2020006341A1
(en)
|
2018-06-29 |
2020-01-02 |
Conatus Pharmaceuticals, Inc. |
(s)-3-(2-(4-(benzyl)-3-oxopiperazin-1-yl)acetamido)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid derivatives and related compounds as caspase inhibitors for treating cardiovascular diseases
|
|
MX2021000786A
(es)
|
2018-07-20 |
2021-06-15 |
Pf Medicament |
Receptor para supresor de ig del dominio v de activación de células t (vista).
|
|
WO2020019247A1
(en)
|
2018-07-26 |
2020-01-30 |
Xw Laboratories, Inc. |
Compounds as neurokinin-1 receptor antagonists and uses thereof
|
|
WO2020024060A1
(en)
|
2018-08-01 |
2020-02-06 |
Mcmaster University |
Methods for inhibiting microbe growth
|
|
IL320987A
(en)
|
2018-08-15 |
2025-07-01 |
Neurocrine Biosciences Inc |
Methods for the administration of certain vmat2 inhibitors
|
|
CN112804998A
(zh)
|
2018-08-17 |
2021-05-14 |
文涵治疗有限公司 |
Ag10的制剂
|
|
ES2947089T3
(es)
|
2018-09-30 |
2023-08-01 |
Xwpharma Ltd |
Compuestos como antagonistas del receptor histamínico 3 neuronal y usos de los mismos
|
|
CA3117968A1
(en)
|
2018-11-01 |
2020-05-07 |
Kura Oncology, Inc. |
Methods of treating cancer with farnesyltransferase inhibitors
|
|
WO2020132071A1
(en)
|
2018-12-19 |
2020-06-25 |
Shy Therapeutics. Llc |
Compounds that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and f1brotic disease
|
|
WO2020128033A1
(en)
|
2018-12-20 |
2020-06-25 |
Institut Pasteur |
Cellular metabolism of hiv-1 reservoir seeding in cd4+ t cells
|
|
KR20210106513A
(ko)
|
2018-12-21 |
2021-08-30 |
쿠라 온콜로지, 인크. |
편평 세포 암종을 위한 요법
|
|
TWI839461B
(zh)
|
2019-02-06 |
2024-04-21 |
美商戴斯阿爾法股份有限公司 |
Il-17a調節物及其用途
|
|
US20220142983A1
(en)
|
2019-03-01 |
2022-05-12 |
Kura Oncology, Inc. |
Methods of treating cancer with farnesyltransferase inhibitors
|
|
US11597703B2
(en)
|
2019-03-07 |
2023-03-07 |
Histogen, Inc. |
Caspase inhibitors and methods of use thereof
|
|
US20220143006A1
(en)
|
2019-03-15 |
2022-05-12 |
Kura Oncology, Inc. |
Methods of treating cancer with farnesyltransferase inhibitors
|
|
JP7641232B2
(ja)
|
2019-03-29 |
2025-03-06 |
クラ オンコロジー, インコーポレイテッド |
ファルネシルトランスフェラーゼ阻害剤による扁平上皮癌の治療方法
|
|
US20220168296A1
(en)
|
2019-04-01 |
2022-06-02 |
Kura Oncology, Inc. |
Methods of treating cancer with farnesyltransferase inhibitors
|
|
MX2021012690A
(es)
|
2019-04-19 |
2022-01-31 |
Ligand Pharm Inc |
Formas cristalinas y metodos para producir formas cristalinas de un compuesto.
|
|
US20220305001A1
(en)
|
2019-05-02 |
2022-09-29 |
Kura Oncology, Inc. |
Methods of treating acute myeloid leukemia with farnesyltransferase inhibitors
|
|
ES3036313T3
(en)
|
2019-05-20 |
2025-09-17 |
Nirvana Sciences Inc |
Narrow emission dyes, compositions comprising same, and methods for making and using same
|
|
WO2020236818A1
(en)
|
2019-05-20 |
2020-11-26 |
Nirvana Sciences Inc. |
Narrow emission dyes, compositions comprising same, and methods for making and using same
|
|
WO2020247345A1
(en)
|
2019-06-03 |
2020-12-10 |
Biotheryx, Inc. |
Non-hygroscopic crystalline salts of a pyrazole compound, and pharmaceutical compositions and use thereof
|
|
WO2021007474A1
(en)
|
2019-07-11 |
2021-01-14 |
Cura Therapeutics, Llc |
Phenyl compounds and pharmaceutical compositions thereof, and their therapeutic applications
|
|
US20220274922A1
(en)
|
2019-07-11 |
2022-09-01 |
Cura Therapeutics, Llc |
Sulfone compounds and pharmaceutical compositions thereof, and their therapeutic applications
|
|
CN118903087A
(zh)
|
2019-07-26 |
2024-11-08 |
埃斯佩尔维塔治疗股份有限公司 |
可用于预防或治疗疾病的官能化的长链烃一元和二元羧酸
|
|
US10940141B1
(en)
|
2019-08-23 |
2021-03-09 |
Neurocrine Biosciences, Inc. |
Methods for the administration of certain VMAT2 inhibitors
|
|
JP7566889B2
(ja)
|
2019-09-16 |
2024-10-15 |
ダイス・アルファ・インコーポレイテッド |
Il-17aモジュレーターおよびその使用
|
|
WO2021059023A1
(en)
|
2019-09-26 |
2021-04-01 |
Abionyx Pharma Sa |
Compounds useful for treating liver diseases
|
|
ES2981468T3
(es)
|
2019-10-11 |
2024-10-09 |
Waterstone Pharmaceuticals Wuhan Co Ltd |
WS-635 para su uso en el tratamiento de la disfunción cognitiva postoperatoria
|
|
CN114901280B
(zh)
|
2019-11-05 |
2025-05-27 |
德米拉公司 |
MrgprX2拮抗剂及其用途
|
|
US20230002336A1
(en)
|
2019-11-05 |
2023-01-05 |
Dermira, Inc. |
MrgprX2 Antagonists and Uses Thereof
|
|
JP7712922B2
(ja)
|
2019-11-05 |
2025-07-24 |
デルミラ インコーポレイテッド |
炎症性障害を治療するためのMrgprX2アンタゴニスト
|
|
TW202136238A
(zh)
|
2020-01-06 |
2021-10-01 |
大陸商廣東東陽光藥業有限公司 |
RORγt抑制劑及其製備方法和用途
|
|
TW202136237A
(zh)
|
2020-01-06 |
2021-10-01 |
大陸商廣東東陽光藥業有限公司 |
RORγt抑制劑及其製備方法和用途
|
|
US11529331B2
(en)
|
2020-05-29 |
2022-12-20 |
Boulder Bioscience Llc |
Methods for improved endovascular thrombectomy using 3,3′-diindolylmethane
|
|
US20230227466A1
(en)
|
2020-06-18 |
2023-07-20 |
Shy Therapeutics, Llc |
Substituted thienopyrimidines that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease
|
|
WO2021262992A1
(en)
|
2020-06-24 |
2021-12-30 |
Neurobo Pharmaceuticals, Inc. |
Gemcabene for treatment of cytokine storms and viral-induced inflammation
|
|
US20230312551A1
(en)
|
2020-06-30 |
2023-10-05 |
Sunshine Lake Pharma Co., Ltd. |
Salt of 2-(substituted pyrimidinyl) thiazole carboxamide compound, and composition and use thereof
|
|
US12024521B2
(en)
|
2020-06-30 |
2024-07-02 |
Prosetta Biosciences, Inc. |
Isoquinoline derivatives, methods of synthesis and uses thereof
|
|
US20240317681A1
(en)
|
2020-07-07 |
2024-09-26 |
Sunshine Lake Pharma Co., Ltd. |
Pyrrolidine amide derivative salt and use thereof
|
|
US11541009B2
(en)
|
2020-09-10 |
2023-01-03 |
Curemark, Llc |
Methods of prophylaxis of coronavirus infection and treatment of coronaviruses
|
|
US20240025863A1
(en)
|
2020-09-16 |
2024-01-25 |
Biotheryx, Inc. |
Sos1 protein degraders, pharmaceutical compositions thereof, and their therapeutic applications
|
|
WO2022087335A1
(en)
|
2020-10-23 |
2022-04-28 |
Biotheryx, Inc. |
Kras protein degraders, pharmaceutical compositions thereof, and their therapeutic applications
|
|
AU2021402911A1
(en)
|
2020-12-14 |
2023-07-06 |
Biotheryx, Inc. |
Pde4 degraders, pharmaceutical compositions, and therapeutic applications
|
|
CA3199509A1
(en)
|
2020-12-16 |
2023-06-23 |
Gopal Krishna |
Dosing of fedratinib
|
|
US20240124483A1
(en)
|
2021-01-27 |
2024-04-18 |
Shy Therapeutics, Llc |
Methods for the Treatment of Fibrotic Disease
|
|
US20240309015A1
(en)
|
2021-01-27 |
2024-09-19 |
Shy Therapeutics, Llc |
Methods for the Treatment of Fibrotic Disease
|
|
WO2022189856A1
(en)
|
2021-03-08 |
2022-09-15 |
Abionyx Pharma Sa |
Compounds useful for treating liver diseases
|
|
JP2024510196A
(ja)
|
2021-03-10 |
2024-03-06 |
ダイス・モレキュールズ・エスブイ・インコーポレイテッド |
アルファvベータ6およびアルファvベータ1インテグリン阻害剤およびその使用
|
|
EP4326721A1
(en)
|
2021-04-22 |
2024-02-28 |
Protego Biopharma, Inc. |
Spirocyclic imidazolidinones and imidazolidinediones for treatment of light chain amyloidosis
|
|
WO2022251533A1
(en)
|
2021-05-27 |
2022-12-01 |
Protego Biopharma, Inc. |
Heteroaryl diamide ire1/xbp1s activators
|
|
WO2022266249A1
(en)
|
2021-06-16 |
2022-12-22 |
Biotheryx, Inc. |
Kras protein degraders, pharmaceutical compositions thereof, and their therapeutic applications
|
|
WO2022266248A1
(en)
|
2021-06-16 |
2022-12-22 |
Biotheryx, Inc. |
Sos1 protein degraders, pharmaceutical compositions thereof, and their therapeutic applications
|
|
US20240358722A1
(en)
|
2021-09-14 |
2024-10-31 |
Impact Biomedicines, Inc. |
Methods of administering fedratinib
|
|
JP2024539134A
(ja)
|
2021-10-22 |
2024-10-28 |
プロセッタ バイオサイエンシズ, インク. |
新規な宿主標的汎呼吸器抗ウイルス小分子治療薬
|
|
CN119504706A
(zh)
|
2021-11-30 |
2025-02-25 |
库拉肿瘤学公司 |
具有法尼基转移酶抑制活性的大环化合物
|
|
US11932665B2
(en)
|
2022-01-03 |
2024-03-19 |
Lilac Therapeutics, Inc. |
Cyclic thiol prodrugs
|
|
JP2025501308A
(ja)
|
2022-01-03 |
2025-01-17 |
ライラック セラピューティクス, インク. |
非環式チオールプロドラッグ
|
|
CN118922189A
(zh)
|
2022-03-02 |
2024-11-08 |
线粒体能量有限公司 |
衍生自烟酸和核糖的新型前药
|
|
GB2619907A
(en)
|
2022-04-01 |
2023-12-27 |
Kanna Health Ltd |
Novel crystalline salt forms of mesembrine
|
|
AU2023252917A1
(en)
|
2022-04-14 |
2024-11-28 |
Bristol-Myers Squibb Company |
Novel gspt1 compounds and methods of use of the novel compounds
|
|
IL316794A
(en)
|
2022-05-10 |
2025-01-01 |
Biotheryx Inc |
CDK protease inhibitors, pharmaceuticals and therapeutic applications
|
|
AU2023310177A1
(en)
|
2022-07-21 |
2025-03-06 |
Antiva Biosciences, Inc. |
Compositions and dosage forms for treatment of hpv infection and hpv-induced neoplasia
|
|
CA3267079A1
(en)
|
2022-09-09 |
2024-03-14 |
Innovo Therapeutics, Inc. |
CK1α AND DOUBLE CK1α/GSPT1 DEGRADATION COMPOUNDS
|
|
WO2024073473A1
(en)
|
2022-09-30 |
2024-04-04 |
Boulder Bioscience Llc |
Compositions comprising 3,3'-diindolylmethane for treating non-hemorrhagic closed head injury
|
|
EP4608839A1
(en)
|
2022-10-26 |
2025-09-03 |
Protego Biopharma, Inc. |
Spirocycle containing bicyclic heteroaryl compounds
|
|
EP4608834A1
(en)
|
2022-10-26 |
2025-09-03 |
Protego Biopharma, Inc. |
Spirocycle containing pyridine compounds
|
|
WO2024092037A1
(en)
|
2022-10-26 |
2024-05-02 |
Protego Biopharma, Inc. |
Spirocycle containing pyridone compounds
|
|
EP4626864A1
(en)
|
2022-11-30 |
2025-10-08 |
Protego Biopharma, Inc. |
Linear heteroaryl diamide ire1/xbp1s activators
|
|
EP4626865A1
(en)
|
2022-11-30 |
2025-10-08 |
Protego Biopharma, Inc. |
Cyclic pyrazole diamide ire1/xbp1s activators
|
|
WO2025063888A1
(en)
|
2023-09-19 |
2025-03-27 |
Kancure Pte. Ltd. |
Survivin-targeted compounds
|
|
WO2025072489A2
(en)
|
2023-09-27 |
2025-04-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Analogues of n-lactoyl-phenylalanine, methods of synthesis, and methods of use
|
|
US20250122182A1
(en)
|
2023-09-27 |
2025-04-17 |
Isosterix, Inc. |
MYST Inhibitors
|
|
WO2025085416A1
(en)
|
2023-10-16 |
2025-04-24 |
Bristol-Myers Squibb Company |
Gspt1 compounds and methods of use of the compounds
|
|
GB2636969A
(en)
|
2023-11-24 |
2025-07-09 |
Ontrack Therapeutics Ltd |
Novel crystalline salt forms
|
|
WO2025147691A1
(en)
|
2024-01-04 |
2025-07-10 |
Innovo Therapeutics, Inc. |
Compositions and methods for degrading aryl hydrocarbon receptor nuclear translocator protein
|
|
WO2025179161A1
(en)
|
2024-02-21 |
2025-08-28 |
Innovo Therapeutics, Inc. |
Protein degrading compounds
|
|
WO2025201633A1
(en)
|
2024-03-26 |
2025-10-02 |
Chen Gefei |
An agent for reducing amyloid formation
|
|
WO2025231261A1
(en)
|
2024-05-01 |
2025-11-06 |
Protego Biopharma, Inc. |
Bicyclic and heterocyclic amide compounds
|
|
WO2025255341A1
(en)
|
2024-06-05 |
2025-12-11 |
Protego Biopharma, Inc. |
Tetrahydrofuranyl ire1/xbp1s activators
|