PL2318035T3 - Sposoby i kompozycje do leczenia objawów zaburzeń neurologicznych i zaburzeń zdrowia psychicznego - Google Patents

Sposoby i kompozycje do leczenia objawów zaburzeń neurologicznych i zaburzeń zdrowia psychicznego

Info

Publication number
PL2318035T3
PL2318035T3 PL09774422T PL09774422T PL2318035T3 PL 2318035 T3 PL2318035 T3 PL 2318035T3 PL 09774422 T PL09774422 T PL 09774422T PL 09774422 T PL09774422 T PL 09774422T PL 2318035 T3 PL2318035 T3 PL 2318035T3
Authority
PL
Poland
Prior art keywords
neurological
symptoms
compositions
treatment
methods
Prior art date
Application number
PL09774422T
Other languages
English (en)
Inventor
Joan M Fallon
Original Assignee
Curemark Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curemark Llc filed Critical Curemark Llc
Publication of PL2318035T3 publication Critical patent/PL2318035T3/pl

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/465Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4826Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/488Aspartic endopeptidases (3.4.23), e.g. pepsin, chymosin, renin, cathepsin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/50Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/976Trypsin; Chymotrypsin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders
    • G01N2800/2821Alzheimer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/30Psychoses; Psychiatry
    • G01N2800/304Mood disorders, e.g. bipolar, depression
PL09774422T 2008-07-01 2009-07-01 Sposoby i kompozycje do leczenia objawów zaburzeń neurologicznych i zaburzeń zdrowia psychicznego PL2318035T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7746308P 2008-07-01 2008-07-01
EP09774422.1A EP2318035B1 (en) 2008-07-01 2009-07-01 Methods and compositions for the treatment of symptoms of neurological and mental health disorders
PCT/US2009/049374 WO2010002972A1 (en) 2008-07-01 2009-07-01 Methods and compositions for the treatment of symptoms of neurological and mental health disorders

Publications (1)

Publication Number Publication Date
PL2318035T3 true PL2318035T3 (pl) 2019-10-31

Family

ID=41466313

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09774422T PL2318035T3 (pl) 2008-07-01 2009-07-01 Sposoby i kompozycje do leczenia objawów zaburzeń neurologicznych i zaburzeń zdrowia psychicznego

Country Status (5)

Country Link
US (2) US11016104B2 (pl)
EP (1) EP2318035B1 (pl)
ES (1) ES2732453T3 (pl)
PL (1) PL2318035T3 (pl)
WO (1) WO2010002972A1 (pl)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6632429B1 (en) 1999-12-17 2003-10-14 Joan M. Fallon Methods for treating pervasive development disorders
US20070053895A1 (en) 2000-08-14 2007-03-08 Fallon Joan M Method of treating and diagnosing parkinsons disease and related dysautonomic disorders
US8030002B2 (en) 2000-11-16 2011-10-04 Curemark Llc Methods for diagnosing pervasive development disorders, dysautonomia and other neurological conditions
US20080058282A1 (en) 2005-08-30 2008-03-06 Fallon Joan M Use of lactulose in the treatment of autism
WO2008083513A1 (fr) 2006-12-13 2008-07-17 Beijing Gingko-Group Biological Technology Co., Ltd. Extrait de pellicule de soja noir et procédé de préparation et d'utilisation de cet extrait
US8658163B2 (en) 2008-03-13 2014-02-25 Curemark Llc Compositions and use thereof for treating symptoms of preeclampsia
US8084025B2 (en) 2008-04-18 2011-12-27 Curemark Llc Method for the treatment of the symptoms of drug and alcohol addiction
US9320780B2 (en) 2008-06-26 2016-04-26 Curemark Llc Methods and compositions for the treatment of symptoms of Williams Syndrome
PL2318035T3 (pl) 2008-07-01 2019-10-31 Curemark Llc Sposoby i kompozycje do leczenia objawów zaburzeń neurologicznych i zaburzeń zdrowia psychicznego
US10776453B2 (en) 2008-08-04 2020-09-15 Galenagen, Llc Systems and methods employing remote data gathering and monitoring for diagnosing, staging, and treatment of Parkinsons disease, movement and neurological disorders, and chronic pain
US20100092447A1 (en) 2008-10-03 2010-04-15 Fallon Joan M Methods and compositions for the treatment of symptoms of prion diseases
JP2012514604A (ja) 2009-01-06 2012-06-28 キュレロン リミテッド ライアビリティ カンパニー 大腸菌(E.coli)による経口感染の治療または予防のための組成物および方法
BRPI1007378A2 (pt) 2009-01-06 2020-08-18 Curemark Llc composições e métodos para o tratamento ou prevenção de infecções por staphylococcus aureus e para a erradicação ou redução de staphylococcus aureus sobre superfícies.
US9056050B2 (en) 2009-04-13 2015-06-16 Curemark Llc Enzyme delivery systems and methods of preparation and use
US9511125B2 (en) 2009-10-21 2016-12-06 Curemark Llc Methods and compositions for the treatment of influenza
EP2701733B1 (en) * 2011-04-21 2019-04-03 Curemark, LLC Compounds for the treatment of neuropsychiatric disorders
US20120303481A1 (en) * 2011-05-25 2012-11-29 Louisn Jai Felix System and Method for Dynamic Object Mapping
US9109177B2 (en) 2011-12-12 2015-08-18 Ensyn Renewables, Inc. Systems and methods for renewable fuel
US20130224172A1 (en) 2012-01-03 2013-08-29 Curemark, Llc Methods of treating behavioral symptoms of neurological and mental disorders
US20130304151A1 (en) * 2012-05-14 2013-11-14 Autonomic Technologies, Inc. Stimulation method for treatment of medical conditions
US10350278B2 (en) 2012-05-30 2019-07-16 Curemark, Llc Methods of treating Celiac disease
US9550780B2 (en) 2012-09-18 2017-01-24 Auspex Pharmaceuticals, Inc. Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2
IN2015DN01662A (pl) 2012-09-18 2015-07-03 Auspex Pharmaceuticals Inc
CN104797248B (zh) 2012-09-19 2017-10-31 格雷斯珀公司 用于改善脑功能的组合物
WO2015077521A1 (en) * 2013-11-22 2015-05-28 Auspex Pharmaceuticals, Inc. Benzoquinoline inhibitors of vesicular monoamine transporter 2
US20160303110A1 (en) * 2013-11-22 2016-10-20 Auspex Pharmaceuticals, Inc. Methods of treating abnormal muscular activity
BR112016012747B1 (pt) 2013-12-03 2022-07-12 Auspex Pharmaceuticals, Inc Processo de preparação de uma mistura racêmica de (rr,ss)-d6-tetrabenazina
HRP20221106T1 (hr) 2015-03-06 2022-11-25 Auspex Pharmaceuticals, Inc. Postupci liječenja abnormalnih nevoljnih poremećaja pokreta
WO2022040022A1 (en) * 2020-08-18 2022-02-24 St. Jude Children's Research Hospital, Inc. Use of amylase or maltose to treat or prevent neurodegeneration
US11541009B2 (en) 2020-09-10 2023-01-03 Curemark, Llc Methods of prophylaxis of coronavirus infection and treatment of coronaviruses
WO2023200281A1 (ko) * 2022-04-15 2023-10-19 재단법인대구경북과학기술원 알츠하이머병 또는 경도 인지장애 진단을 위한 비응집성 용해조성물 및 이를 이용한 진단 방법

Family Cites Families (282)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE491927A (pl) 1948-10-30
US3002883A (en) 1959-07-29 1961-10-03 Dow Chemical Co Disinfectant compositions
US3020310A (en) * 1960-08-12 1962-02-06 Union Carbide Corp Process for the production of tertiary cyanoethylated amines
GB928654A (en) 1960-10-25 1963-06-12 Philips Nv Improvements in or relating to the production of pancreatin
US3322626A (en) 1963-06-13 1967-05-30 Pannett Products Inc Medicinal composition for treating acne and method of using same
FR3071M (fr) 1963-10-18 1965-01-18 Centre Nat Rech Scient Nouvelles protéases pancréatiques, utilisables notamment en gastro-entérologie.
DE1517787A1 (de) 1965-12-06 1970-01-29 Takeda Chemical Industries Ltd Enzympraeparat und Verfahren zu seiner Herstellung
DE1617417A1 (de) 1966-12-08 1971-03-25 Ciba Geigy Pharmazeutisches Praeparat
US3536809A (en) 1969-02-17 1970-10-27 Alza Corp Medication method
US3598123A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3710795A (en) 1970-09-29 1973-01-16 Alza Corp Drug-delivery device with stretched, rate-controlling membrane
US4044126A (en) 1972-04-20 1977-08-23 Allen & Hanburys Limited Steroidal aerosol compositions and process for the preparation thereof
GB1429184A (en) 1972-04-20 1976-03-24 Allen & Hanburys Ltd Physically anti-inflammatory steroids for use in aerosols
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3786615A (en) 1972-11-13 1974-01-22 Pfizer Process for preparing pre-moistened antimicrobial towels
USRE28819E (en) 1972-12-08 1976-05-18 Syntex (U.S.A.) Inc. Dialkylated glycol compositions and medicament preparations containing same
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US3860708A (en) 1973-11-15 1975-01-14 Philips Corp Method of delivering the intestines of human beings from bariumsulphate after barium meal examination
US3940478A (en) 1974-04-29 1976-02-24 Sutures, Inc. Proteolytic enzymes as adjuncts to antibiotic prophylaxis of contaminated wounds
GB1509866A (en) 1975-06-10 1978-05-04 Johnson & Johnson Enteric coated digestive enzyme compositions
US4008719A (en) 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
US4086257A (en) 1976-10-12 1978-04-25 Sears Barry D Phosphatidyl quaternary ammonium compounds
US4199322A (en) 1978-08-17 1980-04-22 The United States Of America As Represented By The Secretary Of Agriculture Antibacterial textile finishes utilizing zinc acetate and hydrogen peroxide
US4241046A (en) 1978-11-30 1980-12-23 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
DE2923279B1 (de) 1979-06-08 1980-11-20 Kali Chemie Pharma Gmbh Verfahren zur Herstellung von Pankreatin-Pellets
US4410545A (en) 1981-02-13 1983-10-18 Syntex (U.S.A.) Inc. Carbonate diester solutions of PGE-type compounds
US4328245A (en) 1981-02-13 1982-05-04 Syntex (U.S.A.) Inc. Carbonate diester solutions of PGE-type compounds
US4432975A (en) 1981-04-13 1984-02-21 Icn Pharmaceuticals, Inc. Process for introducing vitamin B-12 into the bloodstream
US4358603A (en) 1981-04-16 1982-11-09 Syntex (U.S.A.) Inc. Acetal stabilized prostaglandin compositions
US5250418A (en) 1981-10-06 1993-10-05 Boehringer Mannheim Gmbh Process and reagent for determining the activity of chymotrypsin and trypsin in feces
US4395454A (en) 1981-10-09 1983-07-26 Burlington Industries, Inc. Absorbent microbiocidal fabric and product
US4409239A (en) 1982-01-21 1983-10-11 Syntex (U.S.A.) Inc. Propylene glycol diester solutions of PGE-type compounds
DE3377506D1 (en) 1982-12-30 1988-09-01 Nordmark Arzneimittel Gmbh Process for obtaining pancreatin
EP0133438A1 (en) 1983-01-21 1985-02-27 Advanced Drug Technology Corporation Enzyme ointment
US4447412A (en) 1983-02-01 1984-05-08 Bilton Gerald L Enzyme-containing digestive aid compostions
US4456544A (en) 1983-08-05 1984-06-26 Vsesojuzny Nauchno-Issledovatelsky Biotecknichesky Institut Enzyme-containing detergent composition for presterilization treatment of medical instruments and equipment
US6309669B1 (en) 1984-03-16 2001-10-30 The United States Of America As Represented By The Secretary Of The Army Therapeutic treatment and prevention of infections with a bioactive materials encapsulated within a biodegradable-biocompatible polymeric matrix
IE58110B1 (en) 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
DE3650184T2 (de) 1985-12-03 1995-05-11 T Cell Sciences Inc Zellenfreier t-zellenantigenrezeptor und klinische verwendung.
US5023108A (en) 1986-01-13 1991-06-11 Research Corporation Aqueous dispersions of waxes and lipids for pharmaceutical coating
JPS62230714A (ja) 1986-03-31 1987-10-09 Snow Brand Milk Prod Co Ltd 腸溶性カプセル
US4826679A (en) 1986-05-23 1989-05-02 Universite De Montreal Composition and methods for alleviating cystic fibrosis
US4710384A (en) 1986-07-28 1987-12-01 Avner Rotman Sustained release tablets made from microcapsules
DE3738599A1 (de) 1987-11-13 1989-05-24 Raps & Co Gewuerzwerk Eingekapselte trockenhefe in teilchenform, verfahren zu deren herstellung und verwendung derselben
JP2624860B2 (ja) 1988-03-14 1997-06-25 ノボ‐ノルディスク アクティーゼルスカブ 安定化粒状組成物
US5073543A (en) 1988-07-21 1991-12-17 G. D. Searle & Co. Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
CN1039706A (zh) 1988-08-04 1990-02-21 黄族和 人造发菜的制作方法
GB8821049D0 (en) 1988-09-08 1988-10-05 Health Lab Service Board Method & composition for treatment & prevention of viral infections
IT1229203B (it) 1989-03-22 1991-07-25 Bioresearch Spa Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
GB8923788D0 (en) 1989-10-23 1989-12-13 Unilever Plc Enzymatic detergent compositions and their use
US5120548A (en) 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
PH30058A (en) 1989-11-24 1996-11-08 Biochemie Gmbh Pancreation preparations
CA2037178A1 (en) 1990-02-28 1991-08-29 Albert Walter Brzeczko Deprenyl/l-dopa/carbidopa pharmaceutical composition
US5618710A (en) 1990-08-03 1997-04-08 Vertex Pharmaceuticals, Inc. Crosslinked enzyme crystals
NO920067L (no) 1991-01-14 1992-07-15 Ajinomoto Kk Foradditiv for droevtyggere
JP3219765B2 (ja) 1991-04-30 2001-10-15 ザ、プロクター、エンド、ギャンブル、カンパニー タンパク分解酵素を阻害するためのホウ酸系物質−ポリオール複合体を有するビルダー入り液体洗剤
EP0511456A1 (en) 1991-04-30 1992-11-04 The Procter & Gamble Company Liquid detergents with aromatic borate ester to inhibit proteolytic enzyme
US5607863A (en) 1991-05-29 1997-03-04 Smithkline Diagnostics, Inc. Barrier-controlled assay device
US5190775A (en) 1991-05-29 1993-03-02 Balchem Corporation Encapsulated bioactive substances
JPH04364119A (ja) 1991-06-11 1992-12-16 Tsumura & Co 浴剤組成物
IL99628A (en) 1991-10-02 2004-07-25 Yissum Res Dev Co Processes for the preparation of cyclic peptides, and pharmaceutical compositions containing them
WO1993010755A1 (en) 1991-11-25 1993-06-10 Richardson-Vicks, Inc. Compositions for regulating skin wrinkles and/or skin atrophy
US7242988B1 (en) 1991-12-23 2007-07-10 Linda Irene Hoffberg Adaptive pattern recognition based controller apparatus and method and human-factored interface therefore
US5580578A (en) 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US6010715A (en) 1992-04-01 2000-01-04 Bertek, Inc. Transdermal patch incorporating a polymer film incorporated with an active agent
GB9207280D0 (en) 1992-04-02 1992-05-13 Unilever Plc Skin care method and composition
US6024975A (en) 1992-04-08 2000-02-15 Americare International Diagnostics, Inc. Method of transdermally administering high molecular weight drugs with a polymer skin enhancer
AU683215B2 (en) 1992-06-12 1997-11-06 Albert Einstein College Of Medicine Of Yeshiva University Prevention and treatment of peripheral neuropathy
US5260074A (en) 1992-06-22 1993-11-09 Digestive Care Inc. Compositions of digestive enzymes and salts of bile acids and process for preparation thereof
US5460812A (en) 1992-06-22 1995-10-24 Digestive Care Inc. Compositions of digestive enzymes and salts of bile acids and process for preparation thereof
DE4227385A1 (de) 1992-08-19 1994-02-24 Kali Chemie Pharma Gmbh Pankreatinmikropellets
GB9218363D0 (en) 1992-08-28 1992-10-14 Black & Decker Inc Pivoting power tool with table
US5591767A (en) 1993-01-25 1997-01-07 Pharmetrix Corporation Liquid reservoir transdermal patch for the administration of ketorolac
DE4305460C2 (de) 1993-02-23 1997-09-04 Albert Dr Scheller Pharmazeutische oder kosmetische, Enzyme enthaltende Zubereitung, Verfahren zu deren Herstellung und deren Verwendung
JPH06339343A (ja) 1993-04-08 1994-12-13 Ajinomoto Co Inc 反すう動物用飼料添加物
TW310277B (en) 1993-05-21 1997-07-11 Pou Lin Fu Gin Pharm Co The method of preparing enteric-coated pancreatin granules and its dosage forms
DE4332985A1 (de) 1993-09-28 1995-03-30 Konrad Peter Maria Dr Sommer Arzneimittel zur Behandlung der Dysfunktion des exokrinen Pankreas
GB9403250D0 (en) 1994-02-21 1994-04-13 Univ Mcgill Therapeutic use of myelin-associated glycoprotein (mag)
GB9405304D0 (en) 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
US20080311554A1 (en) 1994-05-06 2008-12-18 Slotman Gus J Methods for monitoring patients with severe sepsis and septic shock and for selecting treatments for these patients
IT1270594B (it) 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
US5476661A (en) 1994-10-21 1995-12-19 Elizabeth Arden Co., Division Of Conopco, Inc. Compositions for topical application to skin, hair and nails
US5527678A (en) 1994-10-21 1996-06-18 Vanderbilt University CagB and CagC genes of helicobacter pylori and related compositions
AUPN033894A0 (en) 1994-12-29 1995-01-27 Rowe, J.B. Prevention of adverse behaviour in humans and animals
US5585115A (en) 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
US5983134A (en) 1995-04-23 1999-11-09 Electromagnetic Bracing Systems Inc. Electrophoretic cuff apparatus drug delivery system
US6861053B1 (en) 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
US6562629B1 (en) 1999-08-11 2003-05-13 Cedars-Sinai Medical Center Method of diagnosing irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth by detecting the presence of anti-saccharomyces cerivisiae antibodies (asca) in human serum
US6558708B1 (en) 1995-05-17 2003-05-06 Cedars-Sinai Medical Center Methods for manipulating upper gastrointestinal transit, blood flow, and satiety, and for treating visceral hyperalgesia
CA2220451A1 (en) 1995-05-17 1996-11-21 Cedars-Sinai Medical Center Methods and compositions for improving digestion and absorption in the small intestine
US7048906B2 (en) 1995-05-17 2006-05-23 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
US5686255A (en) 1995-05-24 1997-11-11 Deth; Richard C. Compositions and methods for diagnosing schizophrenia
US5686311A (en) 1995-06-23 1997-11-11 The Children's Mercy Hospital Diagnosis of autism and treatment therefor
AU6682796A (en) 1995-07-21 1997-02-18 New York University Type ii phospholipase a2 and its use in killing gram-positive bacteria
US6167301A (en) 1995-08-29 2000-12-26 Flower; Ronald J. Iontophoretic drug delivery device having high-efficiency DC-to-DC energy conversion circuit
US6699885B2 (en) 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US6852487B1 (en) 1996-02-09 2005-02-08 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
AU2091297A (en) 1996-03-06 1997-09-22 Novo Nordisk A/S A method of killing or inhibiting microbial cells
US5958875A (en) 1996-03-29 1999-09-28 The Regents Of The University Of California Synthetic peptides derivatives with nerve growth factor-like neurotrophic activity
US5750104A (en) 1996-05-29 1998-05-12 Digestive Care Inc. High buffer-containing enteric coating digestive enzyme bile acid compositions and method of treating digestive disorders therewith
US5952178A (en) 1996-08-14 1999-09-14 Exact Laboratories Methods for disease diagnosis from stool samples
US5985317A (en) 1996-09-06 1999-11-16 Theratech, Inc. Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents
GB2318511A (en) 1996-10-23 1998-04-29 Eurand Int Process for the preparation of a pharmaceutical composition for rapid suspension in water
US5860932A (en) 1996-10-24 1999-01-19 Colin Corporation Blood pressure monitor
CA2190418A1 (en) 1996-11-15 1998-05-15 Zhi-Cheng Xiao Neuron and neural tumor growth regulatory system, antibodies thereto and uses thereof
US6100080A (en) 1996-12-18 2000-08-08 Novo Nordisk A/S Method for enzymatic treatment of biofilm
WO1998032336A2 (en) 1997-01-22 1998-07-30 Kerry Ingredients (Uk) Limited Enzyme-based bread improvers
US5860957A (en) 1997-02-07 1999-01-19 Sarcos, Inc. Multipathway electronically-controlled drug delivery system
CA2198317C (en) 1997-02-24 2003-01-07 Mouhsine El Abboudi Method for preparing pancreatin which contains low amounts of residual organic solvent and product thereof
CN1604111A (zh) 1997-03-13 2005-04-06 第一咨询公司 疾病处理系统
US5858758A (en) 1997-05-07 1999-01-12 Incyte Pharmaceuticals, Inc. Human serine protease precursor
US6197746B1 (en) 1998-05-19 2001-03-06 Repligen Corporation Method of using secretin for treating autism
JP2002501616A (ja) 1997-05-19 2002-01-15 リプリゲン コーポレーション 自閉的症候群を鑑別診断および治療する際の助けとするための方法
US6482839B1 (en) 1997-06-02 2002-11-19 Cellegy Pharmaceuticals, Inc. Pyridine-thiols for treatment of a follicular dermatosis
GB2347742B (en) 1997-06-05 2001-11-07 Royal Free Hosp School Med Pharmaceutical composition for RBD
US6534259B1 (en) 1997-06-05 2003-03-18 Andrew Wakefield Regressive behavioral disorder diagnosis
US20010006644A1 (en) 1997-07-31 2001-07-05 David J. Bova Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night
US5948433A (en) 1997-08-21 1999-09-07 Bertek, Inc. Transdermal patch
KR20010031170A (ko) 1997-10-16 2001-04-16 주 데광 신규의 강력한 화장용 또는 약학 조성물
JP4395200B2 (ja) 1997-10-28 2010-01-06 バンドー化学株式会社 皮膚貼付薬シート及びそのための基材シートの製造方法
KR19990072826A (ko) 1998-02-26 1999-09-27 우재영 판크레아틴장용코팅과립의제조방법
EP1405570A1 (en) 1998-03-04 2004-04-07 Ajinomoto Co., Inc. Process for producing ruminant feed additive composition
US20010024660A1 (en) 1999-09-29 2001-09-27 Ismat Ullah Enteric coated pharmaceutical composition and method of manufacturing
US6020314A (en) 1998-08-11 2000-02-01 Milkhaus Laboratory, Inc. Methods for treatment of neurological disorders
ATE429813T1 (de) 1998-10-09 2009-05-15 Gen Mills Inc Verkapselung empfindlicher flüssiger komponenten in eine matrix zur gewinnung diskreter lagerbeständiger partikel
US6149585A (en) 1998-10-28 2000-11-21 Sage Health Management Solutions, Inc. Diagnostic enhancement method and apparatus
US6168569B1 (en) 1998-12-22 2001-01-02 Mcewen James Allen Apparatus and method for relating pain and activity of a patient
US6753306B2 (en) 1998-12-23 2004-06-22 Joseph J. Simpson Germicidal and disinfectant composition
US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
PL199180B1 (pl) 1999-03-17 2008-08-29 Solvay Pharm Gmbh Zastosowanie fizjologicznie dopuszczalnych mieszanin enzymów
US7945451B2 (en) 1999-04-16 2011-05-17 Cardiocom, Llc Remote monitoring system for ambulatory patients
US6210950B1 (en) 1999-05-25 2001-04-03 University Of Medicine And Dentistry Of New Jersey Methods for diagnosing, preventing, and treating developmental disorders due to a combination of genetic and environmental factors
US6153236A (en) 1999-06-03 2000-11-28 Balchem Corporation Low melt encapsulation with high laurate canola oil
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
EP1202743B1 (en) 1999-06-18 2004-10-06 Jon Bragi Bjarnason Pharmaceutical and cosmetic compositions comprising cod serine proteases and their pharmaceutical and cosmetic use
US7395216B2 (en) 1999-06-23 2008-07-01 Visicu, Inc. Using predictive models to continuously update a treatment plan for a patient in a health care location
WO2001012059A1 (en) 1999-08-13 2001-02-22 Synaptec, L.L.C. Method and apparatus of enhancing learning capacity
IL131508A (en) 1999-08-19 2006-12-10 David Cohen Micronexulatory formulations and controlled dispersion of isoflavins from rich masses of sesame and other plants
US6187309B1 (en) 1999-09-14 2001-02-13 Milkaus Laboratory, Inc. Method for treatment of symptoms of central nervous system disorders
US6447772B1 (en) 1999-10-01 2002-09-10 Klaire Laboratories, Inc. Compositions and methods relating to reduction of symptoms of autism
CN1382259A (zh) 1999-10-12 2002-11-27 康奈科斯优化研究和发展有限公司 检测粪便中抗酸微生物的改进方法
US6727073B1 (en) 1999-11-19 2004-04-27 Binax, Inc. Method for detecting enteric disease
US20020103675A1 (en) 1999-11-29 2002-08-01 John Vanelli Apparatus and method for providing consolidated medical information
US6632429B1 (en) 1999-12-17 2003-10-14 Joan M. Fallon Methods for treating pervasive development disorders
US6534063B1 (en) 1999-12-17 2003-03-18 Joan M. Fallon Methods for treating pervasive development disorders
US6251478B1 (en) 1999-12-22 2001-06-26 Balchem Corporation Sensitive substance encapsulation
US6564104B2 (en) 1999-12-24 2003-05-13 Medtronic, Inc. Dynamic bandwidth monitor and adjuster for remote communications with a medical device
US6980958B1 (en) 2000-01-11 2005-12-27 Zycare, Inc. Apparatus and methods for monitoring and modifying anticoagulation therapy of remotely located patients
US6527713B2 (en) 2000-02-14 2003-03-04 First Opinion Corporation Automated diagnostic system and method including alternative symptoms
US6261613B1 (en) 2000-02-15 2001-07-17 General Mills, Inc. Refrigerated and shelf-stable bakery dough products
US6312741B1 (en) 2000-02-22 2001-11-06 Balchem Corporation Encapsulated food acids for preservation of baked goods
US6261595B1 (en) 2000-02-29 2001-07-17 Zars, Inc. Transdermal drug patch with attached pocket for controlled heating device
US7379885B1 (en) 2000-03-10 2008-05-27 David S. Zakim System and method for obtaining, processing and evaluating patient information for diagnosing disease and selecting treatment
CA2342121C (fr) 2000-03-29 2010-05-25 Roquette Freres Mannitol pulverulent et son procede de preparation
US6399101B1 (en) 2000-03-30 2002-06-04 Mova Pharmaceutical Corp. Stable thyroid hormone preparations and method of making same
AUPQ679100A0 (en) 2000-04-07 2000-05-11 Novapharm Research (Australia) Pty Ltd Process and composition for cleaning medical instruments
US6399114B2 (en) 2000-05-26 2002-06-04 C & D Foreman, Inc. Nutritional system for nervous system disorders
US6783757B2 (en) 2000-06-01 2004-08-31 Kirkman Group, Inc. Composition and method for increasing exorphin catabolism to treat autism
US20040062757A1 (en) 2001-06-05 2004-04-01 Finegold Sydney M. Method of testing gastrointestinal diseases associated with species of genus clostridium
AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
AU2001284865A1 (en) 2000-08-14 2002-02-25 Joan M. Fallon Methods for diagnosing and treating dysautonomia and other dysautonomic conditions
US20070053895A1 (en) 2000-08-14 2007-03-08 Fallon Joan M Method of treating and diagnosing parkinsons disease and related dysautonomic disorders
US20020094367A1 (en) 2000-09-08 2002-07-18 Novozymes A/S Dough composition
WO2002019828A1 (en) 2000-09-08 2002-03-14 Novozymes A/S A dough composition comprising a lipid-encapsulated enzyme
IT1319655B1 (it) 2000-11-15 2003-10-23 Eurand Int Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione.
US8030002B2 (en) 2000-11-16 2011-10-04 Curemark Llc Methods for diagnosing pervasive development disorders, dysautonomia and other neurological conditions
US20020119914A1 (en) 2000-12-26 2002-08-29 Deguang Zhu New uses of insulin and pancreatin
US6548556B2 (en) 2000-12-27 2003-04-15 Healthpoint, Ltd. Stable enzymatic wound debrider
GB2370839A (en) 2001-01-06 2002-07-10 Benedikt Timmerman Immunogenic complex useful for disease control
CN1150032C (zh) 2001-01-15 2004-05-19 孙芳梅 治疗小儿腹泻浓缩颗粒及其制备工艺
AR032392A1 (es) 2001-01-19 2003-11-05 Solvay Pharm Gmbh Mezcla de enzimas, preparado farmaceutico y utilizacion de dicho preparado.
US7588757B2 (en) 2001-03-14 2009-09-15 Genzyme Corporation Methods of treating Parkinson's disease using recombinant adeno-associated virus virions
US7107996B2 (en) 2001-04-10 2006-09-19 Ganz Robert A Apparatus and method for treating atherosclerotic vascular disease through light sterilization
US7034134B2 (en) 2001-04-26 2006-04-25 Bristol-Myers Squibb Company Polynucleotide encoding a novel metalloprotease highly expressed in the testis, MMP-29
US7101573B2 (en) 2001-09-28 2006-09-05 Mcneil-Pcc, Inc. Simethicone solid oral dosage form
US7232670B2 (en) 2001-09-28 2007-06-19 St. Jude Children's Research Hospital Targeting proteins to cells expressing mannose receptors via expression in insect cells
US7630911B2 (en) 2001-10-24 2009-12-08 Qtc Management, Inc. Method of automated processing of medical data for insurance and disability determinations
WO2003051345A2 (de) 2001-12-14 2003-06-26 Solvay Pharmaceuticals Gmbh Verwendung von verdauungsenzymgemischen zur behandlung pathologischer bakterieller überwucherung des dünndarms von säugetieren und menschen
US6797291B2 (en) 2002-01-09 2004-09-28 Balchem Corporation Stable hygroscopic compositions and methods for stabilizing hygroscopic ingredients
US6616954B1 (en) 2002-03-14 2003-09-09 Balchem Corporation Solvent released encapsulated yeast
US7226771B2 (en) 2002-04-19 2007-06-05 Diversa Corporation Phospholipases, nucleic acids encoding them and methods for making and using them
EP2266525B1 (en) 2002-05-03 2012-07-11 Martek Biosciences Corporation High quality lipids and methods for producing by enzymatic liberation from biomass
US20040005304A1 (en) 2002-07-08 2004-01-08 Mak Wood, Inc. Novel compositions and methods for treating neurological disorders and associated gastrointestinal conditions
MXPA05001520A (es) 2002-07-08 2005-05-05 Joe S Wilkins Jr Formulaciones antibacteriales.
EP1578935A2 (en) 2002-10-10 2005-09-28 Diversa Corporation Proteases, nucleic acids encoding them and methods for making and using them
EP1413202A1 (en) 2002-10-22 2004-04-28 CSM Nederland B.V. Lipid-encapsulated functional bakery ingredients
US20050079594A1 (en) 2002-10-31 2005-04-14 Karine Marion Method of removing a biofilm
US6835397B2 (en) 2002-12-23 2004-12-28 Balchem Corporation Controlled release encapsulated bioactive substances
US8946151B2 (en) 2003-02-24 2015-02-03 Northern Bristol N.H.S. Trust Frenchay Hospital Method of treating Parkinson's disease in humans by convection-enhanced infusion of glial cell-line derived neurotrophic factor to the putamen
WO2004093883A2 (en) 2003-04-23 2004-11-04 Ferring B.V. Sachet for a pharmaceutical composition
US7780595B2 (en) 2003-05-15 2010-08-24 Clinical Decision Support, Llc Panel diagnostic method and system
EP1633400A2 (en) 2003-05-16 2006-03-15 Pfizer Products Inc. Therapeutic combinations of atypical antipsychotics with gaba modulators, anticonvulsants or benzodiazapines
CN100487098C (zh) 2003-06-05 2009-05-13 柯积发 纳米除菌无磷洗衣粉
EP1653974B1 (en) 2003-06-19 2010-01-06 BODOR, Nicholas S. Enhancement of activity and/or duration of action of soft anti-inflammatory steroids for topical or other local application
US7289761B2 (en) 2003-06-23 2007-10-30 Cardiac Pacemakers, Inc. Systems, devices, and methods for selectively preventing data transfer from a medical device
US7354569B2 (en) 2003-07-11 2008-04-08 Colgate-Palmolive Company Chewable antiplaque confectionery dental composition
JP4891766B2 (ja) 2003-07-29 2012-03-07 ゾルファイ ファーマスーティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング パンクレアチン及び比較可能な組成物のための分析法
US7785584B2 (en) 2003-08-13 2010-08-31 Healthpoint, Ltd. Ointment wound spray
US8524225B2 (en) 2003-09-23 2013-09-03 Dsm Ip Assets B.V. Use of proline specific endoproteases to hydrolyse peptides and proteins
US7381698B2 (en) 2003-12-12 2008-06-03 Chirhoclin, Inc. Methods for treatment of acute pancreatitis
US20050187130A1 (en) 2004-02-23 2005-08-25 Brooker Alan T. Granular laundry detergent composition comprising an anionic detersive surfactant, and low levels of, or no, zeolite builders and phosphate builders
ES2314646T3 (es) 2004-03-22 2009-03-16 Solvay Pharmaceuticals Gmbh Composiciones farmaceuticas por via de productos que contienen lipasa , en particular de pancreatina, que contienen tensioactivos.
US20050232894A1 (en) 2004-04-20 2005-10-20 Weiner Gregory M Antimicrobial skin treatment composition and methods for producing and using an antimicrobial skin treatment composition
ATE473010T1 (de) 2004-05-24 2010-07-15 Novozymes As Enzyme für pharmazeutische anwendung
ITTO20040390A1 (it) 2004-06-10 2004-09-10 Roeder 1956 Farmaceutici S P A Composizione, in particolare per uso farmaceutico, ad azione antiossidante, antinfiammatoria ed immunostimolante.
WO2006009764A1 (en) 2004-06-17 2006-01-26 Amano Enzyme Usa., Ltd. Controlled release formulations of enzymes, microorganisms, and antibodies with mucoadhesive polymers
EP1786510A4 (en) 2004-07-15 2009-12-02 Northstar Neuroscience Inc SYSTEMS AND METHOD FOR INCREASING OR INFLUENCING THE EFFICIENCY OR EFFECTIVENESS OF NEURAL STIMULATION
WO2006031554A2 (en) 2004-09-10 2006-03-23 Novozymes North America, Inc. Methods for preventing, removing, reducing, or disrupting biofilm
US20060198838A1 (en) 2004-09-28 2006-09-07 Fallon Joan M Combination enzyme for cystic fibrosis
LT2198880T (lt) * 2004-10-14 2017-02-27 Eli Lilly And Co. Kompozicijos, turinčios lipazės, proteazės ir amilazės, skirtos kasos nepakankamumo gydymui
CN101039667A (zh) 2004-10-15 2007-09-19 辉瑞大药厂 双相性精神障碍和相关症状的治疗
US20060115467A1 (en) 2004-12-01 2006-06-01 Pangborn Jon B Compositions and methods for the treatment of autism
US20070250119A1 (en) 2005-01-11 2007-10-25 Wicab, Inc. Systems and methods for altering brain and body functions and for treating conditions and diseases of the same
US8187209B1 (en) 2005-03-17 2012-05-29 Great Lakes Neurotechnologies Inc Movement disorder monitoring system and method
EP1861009B1 (en) 2005-03-17 2019-05-22 Robert E. Coifman Apparatus and method for intelligent electronic peak flow meters
US20060294108A1 (en) 2005-04-14 2006-12-28 Adelson Alex M System for and method of managing schedule compliance and bidirectionally communicating in real time between a user and a manager
US20070092501A1 (en) 2005-04-26 2007-04-26 Prothera, Inc. Compositions and methods relating to reduction of symptoms of autism
US20060258599A1 (en) 2005-04-27 2006-11-16 Melanie Childers Methods and composition for the treatment of cystic fibrosis and related illnesses
EP1890700A2 (en) 2005-05-31 2008-02-27 Orexigen Therapeutics, Inc. Methods and compositions for managing psychotic disorders
WO2007002572A2 (en) 2005-06-24 2007-01-04 N-Zymeceuticals, Inc. Nattokinase for reducing whole blood viscosity
EP1913138B1 (en) 2005-07-29 2016-08-24 Abbott Laboratories GmbH Processes for the manufacture of pancreatin powder with low virus content
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
JP5284092B2 (ja) 2005-08-15 2013-09-11 アボット ラボラトリーズ ゲゼルシャフト ミット ベシュレンクテル ハフツング 腸溶コーティングに適したパンクレアチンマイクロペレットコア
US20080058282A1 (en) 2005-08-30 2008-03-06 Fallon Joan M Use of lactulose in the treatment of autism
US20070116695A1 (en) 2005-09-21 2007-05-24 Fallon Joan M Pharmaceutical preparations for attention deficit disorder, attention deficit hyperactivity disorder and other associated disorders
US20100196344A1 (en) 2005-10-14 2010-08-05 Cystic Fibrosis Foundation Therapeutics, Inc. Compositions and methods for treating pancreatic insufficiency
US20070203426A1 (en) 2005-10-20 2007-08-30 Kover Arthur J Method and apparatus for obtaining real time emotional response data over a communications network
US8071089B2 (en) 2005-11-01 2011-12-06 Bio-Cat, Inc. Composition with a fungal (yeast) lipase and method for treating lipid malabsorption in cystic fibrosis as well as people suffering from pancreatic lipase insufficiency
US8728521B2 (en) 2005-12-27 2014-05-20 Hemant N. Joshi Physically/molecularly distributed and/or chemically bound medicaments in empty, hard capsule shells
US8197808B2 (en) 2005-12-27 2012-06-12 Ramot At Tel-Aviv University Ltd. Stable enzymatic preparations and methods of use thereof
BRPI0707440A2 (pt) 2006-02-02 2011-05-03 Dsm Ip Assets Bv produto alimentìcio compreendendo uma protease especìfica de prolina, sua preparação e seu uso para a degradação de peptìdeos de glúten alergêncios ou tóxicos
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
EP2032612A1 (en) 2006-06-23 2009-03-11 Basell Poliolefine Italia S.r.l. Magnesium chloroalkolate-based catalyst precursors
US20080019956A1 (en) 2006-07-24 2008-01-24 Manoj Kumar Enzymatic prevention and control of biofilm
WO2008021987A2 (en) 2006-08-10 2008-02-21 Jon Barron Proteolytic enzyme formulations
WO2008028193A2 (en) 2006-09-01 2008-03-06 Pharmion Corporation Colon-targeted oral formulations of cytidine analogs
DE102006053071A1 (de) 2006-11-10 2008-05-15 Ab Enzymes Gmbh Protein-enthaltender Stoff mit erhöhter Temperaturstabilität
US8066986B2 (en) 2007-02-01 2011-11-29 Master Supplements, Inc. Formulations including digestive enzymes and polysorbate surfactants that enhance the colonization of administered probiotics microoganisms
US20080199448A1 (en) 2007-02-16 2008-08-21 Ross Mairi R Enzyme composition for improving food digestion
AU2008218595B2 (en) 2007-02-20 2012-05-24 Allergan Therapeutics LLC Stable digestive enzyme compositions
US20090117180A1 (en) 2007-02-20 2009-05-07 Giovanni Ortenzi Stable digestive enzyme compositions
US20090018407A1 (en) 2007-03-30 2009-01-15 Searete Llc, A Limited Corporation Of The State Of Delaware Computational user-health testing
AU2008239737A1 (en) 2007-04-13 2008-10-23 Beth Israel Deaconess Medical Center, Inc. Novel nutritional food products for improved digestion and intestinal absorption
JP2008283895A (ja) 2007-05-16 2008-11-27 Osaka City Univ 下痢原性大腸菌検出方法
US20090004285A1 (en) 2007-06-29 2009-01-01 Liangping Yu Stable non-disintegrating dosage forms and method of making same
US20110065628A1 (en) 2007-08-27 2011-03-17 University Of Virginia Patent Foundation Medication Combinations for the Treatment of Alcoholism and Drug Addiction
US20090063402A1 (en) 2007-08-31 2009-03-05 Abbott Diabetes Care, Inc. Method and System for Providing Medication Level Determination
US20090110674A1 (en) * 2007-10-24 2009-04-30 Loizou Nicos C Health supplement
RU2356244C1 (ru) 2007-11-12 2009-05-27 Федеральное государственное учреждение "Томский научно-исследовательский институт курортологии и физиотерапии Федерального агентства по здравоохранению и социальному развитию" (ФГУ "ТНИИКиФ Росздрава") Способ комплексного лечения детей с целиакией на санаторно-курортном этапе
US20090171696A1 (en) 2008-01-02 2009-07-02 David Joseph Allard System and method for patient portal with clinical decision intelligence
US10087493B2 (en) 2008-03-07 2018-10-02 Aptalis Pharma Canada Ulc Method for detecting infectious parvovirus in pharmaceutical preparations
US8658163B2 (en) 2008-03-13 2014-02-25 Curemark Llc Compositions and use thereof for treating symptoms of preeclampsia
US8976007B2 (en) 2008-08-09 2015-03-10 Brian M. Dugan Systems and methods for providing biofeedback information to a cellular telephone and for using such information
US8084025B2 (en) 2008-04-18 2011-12-27 Curemark Llc Method for the treatment of the symptoms of drug and alcohol addiction
CA2728789A1 (en) 2008-06-24 2009-12-30 Micropharma Limited Nitric oxide compositions and devices and methods for cosmesis
US9320780B2 (en) 2008-06-26 2016-04-26 Curemark Llc Methods and compositions for the treatment of symptoms of Williams Syndrome
US20090324730A1 (en) 2008-06-26 2009-12-31 Fallon Joan M Methods and compositions for the treatment of symptoms of complex regional pain syndrome
PL2318035T3 (pl) 2008-07-01 2019-10-31 Curemark Llc Sposoby i kompozycje do leczenia objawów zaburzeń neurologicznych i zaburzeń zdrowia psychicznego
US10776453B2 (en) 2008-08-04 2020-09-15 Galenagen, Llc Systems and methods employing remote data gathering and monitoring for diagnosing, staging, and treatment of Parkinsons disease, movement and neurological disorders, and chronic pain
EP2328609A1 (en) 2008-08-26 2011-06-08 Cystic Fibrosis Foundation Therapeutics, Inc. Rapidly disintegrating tablets comprising lipase, amylase, and protease
US20100092447A1 (en) 2008-10-03 2010-04-15 Fallon Joan M Methods and compositions for the treatment of symptoms of prion diseases
PL2295086T3 (pl) 2008-11-03 2012-09-28 Nordmark Arzneimittel Gmbh & Co Kg Sposób zmniejszania skażenia pankreatyny wirusami i drobnoustrojami
JP2012514604A (ja) 2009-01-06 2012-06-28 キュレロン リミテッド ライアビリティ カンパニー 大腸菌(E.coli)による経口感染の治療または予防のための組成物および方法
BRPI1007378A2 (pt) 2009-01-06 2020-08-18 Curemark Llc composições e métodos para o tratamento ou prevenção de infecções por staphylococcus aureus e para a erradicação ou redução de staphylococcus aureus sobre superfícies.
WO2010096814A1 (en) 2009-02-23 2010-08-26 Eurand, Inc. Controlled-release compositions comprising a proton pump inhibitor
US9056050B2 (en) 2009-04-13 2015-06-16 Curemark Llc Enzyme delivery systems and methods of preparation and use
WO2011000924A1 (en) 2009-07-03 2011-01-06 Abbott Products Gmbh Spray-dried amylase, pharmaceutical preparations comprising the same and use
EP2295039B2 (de) 2009-08-28 2022-10-26 Nordmark Pharma GmbH Verfahren zur Herstellung von Pankreatin-Pellets, insbesondere Pankreatin-Mikropellets, und hiernach hergestellte Pankreatin-Pellets
US20110081320A1 (en) 2009-10-06 2011-04-07 Nubiome, Inc. Treatment/Cure of Autoimmune Disease
US9511125B2 (en) 2009-10-21 2016-12-06 Curemark Llc Methods and compositions for the treatment of influenza
US20110112005A1 (en) 2009-11-12 2011-05-12 Alan Thomas Brooker Laundry Detergent Composition
RU2583926C2 (ru) 2010-01-15 2016-05-10 ИНСЕРМ (Энститю Насьеналь де ла Санте э де ла Решерш Медикаль) Соединения для лечения аутизма
EP2531521B1 (en) 2010-02-02 2017-09-06 Amano Enzyme USA., Ltd. Use of proteases for gluten intolerance
WO2011114225A1 (en) 2010-03-19 2011-09-22 Axcan Pharma Inc. Beta-propiolactone for inactivation of viruses in pharmaceutical pancreatic enzyme preparations
PT2621476E (pt) 2010-10-01 2014-10-16 Aptalis Pharma Ltd Formulações de pancrelipase de baixa potência com revestimento entérico
CA2815044A1 (en) 2010-11-19 2012-05-24 Curemark Llc Preparation and use of combination enzyme and gastrointestinal modulator delivery systems
EP2701733B1 (en) 2011-04-21 2019-04-03 Curemark, LLC Compounds for the treatment of neuropsychiatric disorders
US20130224172A1 (en) 2012-01-03 2013-08-29 Curemark, Llc Methods of treating behavioral symptoms of neurological and mental disorders
CN107261126A (zh) 2012-02-02 2017-10-20 加尔纳根有限责任公司 酶组合物及其用于创伤愈合的用途
US10350278B2 (en) 2012-05-30 2019-07-16 Curemark, Llc Methods of treating Celiac disease
WO2018191233A1 (en) 2017-04-10 2018-10-18 Curemark, Llc Compositions for treating addiction

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