US3786615A - Process for preparing pre-moistened antimicrobial towels - Google Patents
Process for preparing pre-moistened antimicrobial towels Download PDFInfo
- Publication number
- US3786615A US3786615A US00305859A US3786615DA US3786615A US 3786615 A US3786615 A US 3786615A US 00305859 A US00305859 A US 00305859A US 3786615D A US3786615D A US 3786615DA US 3786615 A US3786615 A US 3786615A
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- United States
- Prior art keywords
- moistened
- sheet
- antimicrobial
- stack
- towels
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/00987—Apparatus or processes for manufacturing non-adhesive dressings or bandages
- A61F13/00991—Apparatus or processes for manufacturing non-adhesive dressings or bandages for treating webs, e.g. for moisturising, coating, impregnating or applying powder
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S206/00—Special receptacle or package
- Y10S206/812—Packaged towel
Definitions
- packages of premoistened towels were prepared by placing a stack of towels into a container, saturating the towels with a solution containing an antimicrobial agent, placing a cover on the container and heat sealing a top'on the container to completely seal the package.
- this method is subject to chromatographic effects whereby the antimicrobial agent may tend to concentrate in portions of the stack without being uniformly dispersed through the stack and the individual towels.
- pre-moistened antimicrobial towels can be made by a process which comprises the steps of coating paper or fabric sheet in strip form with a solution of antimicrobial agent in a volatile vehicle; permitting said vehicle to evaporate; transversely perforating said coated sheet into separable towel segments; longitudinally and transversely folding said perforated sheet; arranging said folded and perforated sheet in stack form in a moisture-impervious container; moistening said stack with aqueous liquid; and enclosing said moistened stack with a moisture-impervious cover seal on said container.
- Such a process produces a moistened towel in which the antimicrobial agent is uniformly dispersed on each towel, thereby protecting the product from spoilage andproviding a uniform concentration of antimicrobial agent for the intended use.
- FIG. 1 is a schematic view in section of an apparatus for carrying out the coating step of the invention.
- FIG. 2 is, a side elevation in partial section of a portion of the apparatus of FIG. 1.
- a strip of paper or fabric 2 is drawn past pressure roll 4 in rolling contact with cylinder 6.
- Cylinder 6 is preferably a precision engraved applicator suitable for gravure printing.
- Roll 4 and cylinder 6 are rotated in the directions indicated by the arrows by a drive source not shown.
- Cylinder 6 is partially immersed in antimicrobial solution 8 contained in reservoir 10, and excess solution is removed by doctor blade 12.
- the etched or incised surface of cylinder 6 is thereby moistened or saturated with the antimicrobial solution, and brought into contact with the material to be coated as it travels through the nip created by roll 4 and cylinder 6.
- the speed at which the material passes through the rollers is not critical and may be set at any predetermined speed desired.
- Roll 4 suitably has a resilient surface, e.g., of rubber, whereby strip 2 of paper or other sheet material is pressed into intimate contact with the antimicrobial solution carried by the surface of cylinder 6.
- Cylinder 6 is suitably a conventional gravure roll, e.g., having a diameter of about 9 inches and a width of about 54 inches.
- the surface of cylinder 6 is etched or engraved with a uniform pattern 14 (shown greatly magnified), e.g., a series of cells or wells, each in the form of an inverted truncated right rectangular pyramid to hold the antimicrobial solution.
- This pattern and in particular the size and spacing of the individual cells, determines the quantity of solution transferred to strip 2 in the coating application.
- Preferred patterns are those having about 200-220 cells per lineal inch, each cell having a depth of up to about 0.0012 inch, which, in conjunction with a 25 percent by weight solution of antimicrobial agent, will transfer on the order of 0.1 mg. of said agent per square inch of surface to be coated. Concentrations of 4 to 50 percent by weight will successfully deposit up to 0.2 mg. of agent per square inch.
- the towels are for example made from paper or nonwoven hemp material having a substantial wet strength such as Dexter paper, Grade X 2067 or N 2660, available from The Dexter Corp. of Windsor Locks, Connecticut. Woven or non-woven cloth made of rayon, nylon or cotton, alone or in combination, may also be used.
- Preferred antimicrobial compounds are the quaternary ammonium compounds, e.g., benzalkonium chloride, an alkyl-substituted dimethylbenzyl-ammonium chloride wherein the alkyl substituents each contain 8 to 18 carbon atoms.
- Other well-known antimicrobial agents such as cetyl pyridinium chloride, chlorhexidine, or propyl or methyl paraben, can be substituted wholly or partially for the benzalkonium chloride.
- the optimum amount of antimicrobial agent will vary with the particular agent being used and the end use of the product. However, in the case of quaternary ammonium compounds, a concentration of 0.1-0.2 mg. per square inch of the towelling is generally used.
- Optional ingredients such as local anesthetics, vasoconstrictors, astringents, etc., may also be applied at this step, if desired.
- the volatile vehicle is usually water, a waterethanol or a water-isopropanol mixture, which air dries by spontaneous evaportation.
- the treated towelling material is transversely perforated, and longitudinally and transversely folded, e.g., by means of a conventional zig-zag folding machine capable of producing a transverse shear-cut perforation leaving bonds between the individual sheets, longitudinally folding into a wing fold," and transversely folding into a zig-zag fold.
- zig-zag folding machine capable of producing a transverse shear-cut perforation leaving bonds between the individual sheets, longitudinally folding into a wing fold," and transversely folding into a zig-zag fold.
- the zig-zag folding affords the opportunity of packaging the towels in stack form.
- the stacks are placed in moisture-impervious containers, such as shallow polystyrene trays, and moistened with an aqueous liquid, which may for example be water, water-ethanol or water-isopropanol, optionally containing auxiliary agents, odorants or the like, if desired.
- the containers are then fitted with a moisture-impervious cover seal, e.g., a replaceable lid suitably trapped within a foilbacked paper cover sealed to an outwardly extending lip on the tray.
- a process for preparing pre-moistened antimicrobial towels which comprises the steps of coating paper or fabric sheet in strip form with a solution of antimicrobial agent in a volatile vehicle; permitting said vehicle to evaporate; transversely perforating said coated sheet into separable towel segments; longitudinally and transversely folding said perforated sheet; arranging said folded and perforated sheet in stack form in a moisture-impervious container; moistening said stack with aqueous liquid; and enclosing said moistened stack with a moisture-inpervious cover seal on said woven hemp.
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Manufacturing & Machinery (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Body Washing Hand Wipes And Brushes (AREA)
- Absorbent Articles And Supports Therefor (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Sanitary Thin Papers (AREA)
- Materials For Medical Uses (AREA)
Abstract
A process for the preparation of pre-moistened antimicrobial towels is disclosed.
Description
United States Patent [191 Bauer Jan. 22, 1974 PROCESS FOR PREPARING [5 6] References Cited 0 Ls 3,264,188 8/1966 Gresham 206/57 R X [75] Inventor: Stuart M. Bauer, Succasunna, NJ. 3,481,099 12/1969 Clancy 53/21 FC [73] Assignee: Pfizer Inc., New York, NY.
Primary Examiner-Travis S. McGehee Flledi 1972 Attorney, Agent, or Firm-Francis X. Murphy; Charles [21] APPL No; 305,859 J. Knuth; Allen J. Spiegel 52 us. Cl 53/21 FC, 53/21 FW, 53/36, [57] ABSTRACT 206/57 R A process for the preparation of pre-moistened anti- [51] Int. Cl B65b 63/04 microbial towels is disclosed. [58] Field of Search53/21 FC, 21 FW, 36; 206/57 R 6 Claims, 2 Drawing Figures PROCESS FOR PREPARING PRE-MOISTENED ANTIMICROBIAL TOWELS BACKGROUND OF THE INVENTION This invention relates to a novel process for preparing pre-moistened antimicrobial towels useful for sanitary purposes, e.g., in hemorrhoidal conditions, feminine hygiene, first aid, diaper change cleanups and similar uses.
Previously, packages of premoistened towels were prepared by placing a stack of towels into a container, saturating the towels with a solution containing an antimicrobial agent, placing a cover on the container and heat sealing a top'on the container to completely seal the package. However, this method is subject to chromatographic effects whereby the antimicrobial agent may tend to concentrate in portions of the stack without being uniformly dispersed through the stack and the individual towels.
SUMMARY OF THE INVENTION It has now been found that pre-moistened antimicrobial towels can be made by a process which comprises the steps of coating paper or fabric sheet in strip form with a solution of antimicrobial agent in a volatile vehicle; permitting said vehicle to evaporate; transversely perforating said coated sheet into separable towel segments; longitudinally and transversely folding said perforated sheet; arranging said folded and perforated sheet in stack form in a moisture-impervious container; moistening said stack with aqueous liquid; and enclosing said moistened stack with a moisture-impervious cover seal on said container.
Such a process produces a moistened towel in which the antimicrobial agent is uniformly dispersed on each towel, thereby protecting the product from spoilage andproviding a uniform concentration of antimicrobial agent for the intended use.
BRIEF DESCRIPTION OF THE DRAWING The invention will be better understood by reference to the appended drawings, wherein FIG. 1 is a schematic view in section of an apparatus for carrying out the coating step of the invention, and
FIG. 2 is, a side elevation in partial section of a portion of the apparatus of FIG. 1.
DETAILED DESCRIPTION OF THE INVENTION As shown in FIG. I, a strip of paper or fabric 2 is drawn past pressure roll 4 in rolling contact with cylinder 6. Cylinder 6 is preferably a precision engraved applicator suitable for gravure printing. Roll 4 and cylinder 6 are rotated in the directions indicated by the arrows by a drive source not shown. Cylinder 6 is partially immersed in antimicrobial solution 8 contained in reservoir 10, and excess solution is removed by doctor blade 12. The etched or incised surface of cylinder 6 is thereby moistened or saturated with the antimicrobial solution, and brought into contact with the material to be coated as it travels through the nip created by roll 4 and cylinder 6. The speed at which the material passes through the rollers is not critical and may be set at any predetermined speed desired.
The towels are for example made from paper or nonwoven hemp material having a substantial wet strength such as Dexter paper, Grade X 2067 or N 2660, available from The Dexter Corp. of Windsor Locks, Connecticut. Woven or non-woven cloth made of rayon, nylon or cotton, alone or in combination, may also be used.
Preferred antimicrobial compounds are the quaternary ammonium compounds, e.g., benzalkonium chloride, an alkyl-substituted dimethylbenzyl-ammonium chloride wherein the alkyl substituents each contain 8 to 18 carbon atoms. Other well-known antimicrobial agents, such as cetyl pyridinium chloride, chlorhexidine, or propyl or methyl paraben, can be substituted wholly or partially for the benzalkonium chloride. The optimum amount of antimicrobial agent will vary with the particular agent being used and the end use of the product. However, in the case of quaternary ammonium compounds, a concentration of 0.1-0.2 mg. per square inch of the towelling is generally used. Optional ingredients, such as local anesthetics, vasoconstrictors, astringents, etc., may also be applied at this step, if desired. The volatile vehicle is usually water, a waterethanol or a water-isopropanol mixture, which air dries by spontaneous evaportation.
After drying, the treated towelling material is transversely perforated, and longitudinally and transversely folded, e.g., by means of a conventional zig-zag folding machine capable of producing a transverse shear-cut perforation leaving bonds between the individual sheets, longitudinally folding into a wing fold," and transversely folding into a zig-zag fold. Thus, the expression perforating as employed herein and in the appended claims is to be understood to include the introduction into the strip material of a line of transverse slits defined by residual fiber bonds, or alternatively the introduction of a transverse row of holes.
The zig-zag folding affords the opportunity of packaging the towels in stack form. The stacks are placed in moisture-impervious containers, such as shallow polystyrene trays, and moistened with an aqueous liquid, which may for example be water, water-ethanol or water-isopropanol, optionally containing auxiliary agents, odorants or the like, if desired. The containers are then fitted with a moisture-impervious cover seal, e.g., a replaceable lid suitably trapped within a foilbacked paper cover sealed to an outwardly extending lip on the tray.
What is claimed is:
1. A process for preparing pre-moistened antimicrobial towels which comprises the steps of coating paper or fabric sheet in strip form with a solution of antimicrobial agent in a volatile vehicle; permitting said vehicle to evaporate; transversely perforating said coated sheet into separable towel segments; longitudinally and transversely folding said perforated sheet; arranging said folded and perforated sheet in stack form in a moisture-impervious container; moistening said stack with aqueous liquid; and enclosing said moistened stack with a moisture-inpervious cover seal on said woven hemp.
Claims (6)
1. A process for preparing pre-moistened antimicrobial towels which comprises the steps of coating paper or fabric sheet in strip form with a solution of antimicrobial agent in a volatile vehicle; permitting said vehicle to evaporate; transversely perforating said coated sheet into separable towel segments; longitudinally and transversely folding said perforated sheet; arranging said folded and perforated sheet in stack form in a moisture-impervious container; moistening said stack with aqueous liquid; and enclosing said moistened stack with a moistureinpervious cover seal on said container.
2. The process of claim 1 wherein said coating is effected by gravure printing.
3. The process of claim 1 wherein said antimicrobial agent is a quaternary ammonium compound.
4. The process Of claim 3 wherein said quaternary ammonium compound is benzalkonium chloride.
5. The process of claim 1 wherein said sheet is paper.
6. The process of claim 1 wherein said sheet is non-woven hemp.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30585972A | 1972-11-13 | 1972-11-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
US3786615A true US3786615A (en) | 1974-01-22 |
Family
ID=23182674
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US00305859A Expired - Lifetime US3786615A (en) | 1972-11-13 | 1972-11-13 | Process for preparing pre-moistened antimicrobial towels |
Country Status (5)
Country | Link |
---|---|
US (1) | US3786615A (en) |
JP (1) | JPS4977753A (en) |
CA (1) | CA1003329A (en) |
DE (1) | DE2350036A1 (en) |
GB (1) | GB1416944A (en) |
Cited By (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3895474A (en) * | 1972-11-13 | 1975-07-22 | Pfizer | Process for preparing pre-moistened antimicrobial towels |
US4625026A (en) * | 1982-12-30 | 1986-11-25 | Biomeasure, Inc. | 2-amino-4-oxo-tricyclicpyrimidines having antiviral activities against herpes simplex virus type II infections |
US4627936A (en) * | 1984-10-05 | 1986-12-09 | Gould Paper Corp. | Towel premoistened with antistatic solution for cleaning cathode-ray tubes and the like |
US4788060A (en) * | 1986-10-27 | 1988-11-29 | Abbott Laboratories | Multiple electrolyte douche and wipe composition |
US4814335A (en) * | 1982-12-30 | 1989-03-21 | Biomeasure, Incorporated | Antiviral compounds |
US4817790A (en) * | 1986-04-22 | 1989-04-04 | Amir Porat | Towelette |
US5091102A (en) * | 1988-11-15 | 1992-02-25 | Nordico, Inc. | Method of making a dry antimicrobial fabric |
US5094770A (en) * | 1988-11-15 | 1992-03-10 | Nordico, Inc. | Method of preparing a substantially dry cleaning wipe |
US5527255A (en) * | 1994-10-17 | 1996-06-18 | Mansfield; Peter W. | Apparatus and method for preparing disposable towels |
US5697577A (en) * | 1996-02-27 | 1997-12-16 | Ogden; Terry P. | Premoistened toilet paper dispenser |
US6207596B1 (en) * | 1998-11-09 | 2001-03-27 | The Procter & Gamble Company | Disposable premoistened wipe containing an antimicrobial protease inhibitor |
US20030031898A1 (en) * | 2001-08-03 | 2003-02-13 | Capps Charles L. | Antifungal gypsum board |
US20030157856A1 (en) * | 2002-01-14 | 2003-08-21 | Schroeder Gary L. | Moist wipe and method of making same |
US6641826B2 (en) | 2000-06-26 | 2003-11-04 | Playtex Products, Inc. | Wipe with improved cleansing |
US20040071758A1 (en) * | 1998-12-01 | 2004-04-15 | The Procter & Gamble Company | Tissue paper product, and process for making the product |
US6737068B2 (en) | 2001-10-01 | 2004-05-18 | Playtex Products, Inc. | Wipe formulation |
US20040116031A1 (en) * | 2002-11-12 | 2004-06-17 | Brennan Jonathan Paul | Process and apparatus for preparing a molded, textured, spunlaced, nonwoven web |
US20070238383A1 (en) * | 2006-04-06 | 2007-10-11 | The Procter & Gamble Company | One-dimensional continuous molded element |
US20080118540A1 (en) * | 2006-11-22 | 2008-05-22 | Cmi Enterprises, Inc. | System and method for using nanoparticles for antimicrobial activity |
USRE40495E1 (en) * | 2001-09-19 | 2008-09-09 | Commun-I-Tec, Ltd. | Substrate treated with a binder comprising positive ions |
US20100065445A1 (en) * | 2008-09-18 | 2010-03-18 | Huckleberry Toys | Pre-Packaged, Customized, Woven, Wet Towel |
US20110038909A1 (en) * | 2006-11-22 | 2011-02-17 | Heirloom Holdings | System and Method for Using Nanoparticles for Antimicrobial Activity |
EP2947100A1 (en) | 2009-01-06 | 2015-11-25 | Curelon LLC | Oral compositions for the treatment or the prevention of infections by E. Coli |
US20160021888A1 (en) * | 2014-04-28 | 2016-01-28 | American Sterilizer Company | Wipe for killing spores |
EP3064217A1 (en) | 2009-01-06 | 2016-09-07 | Curelon LLC | Compositions comprising protease, amylase and lipase for use in the treatment of staphylococcus aureus infections |
US10463754B2 (en) | 2014-04-28 | 2019-11-05 | American Sterilizer Company | Process for decontaminating or sterilizing an article |
US10750749B2 (en) | 2014-04-28 | 2020-08-25 | American Sterilizer Company | Process and composition for killing spores |
US10940187B2 (en) | 2011-04-21 | 2021-03-09 | Curemark, Llc | Method of treatment of schizophreniform disorder |
US11016104B2 (en) | 2008-07-01 | 2021-05-25 | Curemark, Llc | Methods and compositions for the treatment of symptoms of neurological and mental health disorders |
US11033563B2 (en) | 2005-08-30 | 2021-06-15 | Curemark, Llc | Use of lactulose in the treatment of autism |
US11045527B2 (en) | 2008-03-13 | 2021-06-29 | Curemark, Llc | Method of diagnosing preeclampsia or pregnancy-induced hypertension |
US11235038B2 (en) | 2008-04-18 | 2022-02-01 | Curemark, Llc | Pharmaceutical preparation for the treatment of the symptoms of addiction and method of diagnosing same |
US11305930B2 (en) * | 2014-10-30 | 2022-04-19 | Veltek Associates, Inc. | Wipe container |
US11364287B2 (en) | 2012-05-30 | 2022-06-21 | Curemark, Llc | Methods of treating celiac disease |
US11419821B2 (en) | 2009-04-13 | 2022-08-23 | Curemark, Llc | Enzyme delivery systems and methods of preparation and use |
US11541009B2 (en) | 2020-09-10 | 2023-01-03 | Curemark, Llc | Methods of prophylaxis of coronavirus infection and treatment of coronaviruses |
US11662279B2 (en) | 2016-08-15 | 2023-05-30 | Veltek Associates, Inc. | Portable air sampler |
US12006338B2 (en) | 2019-10-18 | 2024-06-11 | Topikos Scientific, Inc. | Antimicrobial organosilanes |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5290362A (en) * | 1976-01-24 | 1977-07-29 | Shiroki Kk | Wet towel |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3264188A (en) * | 1963-01-16 | 1966-08-02 | Kimberly Clark Co | Sanitary impregnated skin wiper |
US3481099A (en) * | 1968-09-09 | 1969-12-02 | Colgate Palmolive Co | Packaging apparatus and method |
-
1972
- 1972-11-13 US US00305859A patent/US3786615A/en not_active Expired - Lifetime
-
1973
- 1973-09-21 GB GB4450873A patent/GB1416944A/en not_active Expired
- 1973-09-26 CA CA181,949A patent/CA1003329A/en not_active Expired
- 1973-10-05 DE DE19732350036 patent/DE2350036A1/en active Pending
- 1973-10-09 JP JP11293673A patent/JPS4977753A/ja active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3264188A (en) * | 1963-01-16 | 1966-08-02 | Kimberly Clark Co | Sanitary impregnated skin wiper |
US3481099A (en) * | 1968-09-09 | 1969-12-02 | Colgate Palmolive Co | Packaging apparatus and method |
Cited By (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3895474A (en) * | 1972-11-13 | 1975-07-22 | Pfizer | Process for preparing pre-moistened antimicrobial towels |
US4625026A (en) * | 1982-12-30 | 1986-11-25 | Biomeasure, Inc. | 2-amino-4-oxo-tricyclicpyrimidines having antiviral activities against herpes simplex virus type II infections |
US4814335A (en) * | 1982-12-30 | 1989-03-21 | Biomeasure, Incorporated | Antiviral compounds |
US4627936A (en) * | 1984-10-05 | 1986-12-09 | Gould Paper Corp. | Towel premoistened with antistatic solution for cleaning cathode-ray tubes and the like |
US4817790A (en) * | 1986-04-22 | 1989-04-04 | Amir Porat | Towelette |
US4788060A (en) * | 1986-10-27 | 1988-11-29 | Abbott Laboratories | Multiple electrolyte douche and wipe composition |
US5091102A (en) * | 1988-11-15 | 1992-02-25 | Nordico, Inc. | Method of making a dry antimicrobial fabric |
US5094770A (en) * | 1988-11-15 | 1992-03-10 | Nordico, Inc. | Method of preparing a substantially dry cleaning wipe |
US5527255A (en) * | 1994-10-17 | 1996-06-18 | Mansfield; Peter W. | Apparatus and method for preparing disposable towels |
US5697577A (en) * | 1996-02-27 | 1997-12-16 | Ogden; Terry P. | Premoistened toilet paper dispenser |
US6207596B1 (en) * | 1998-11-09 | 2001-03-27 | The Procter & Gamble Company | Disposable premoistened wipe containing an antimicrobial protease inhibitor |
US20040071758A1 (en) * | 1998-12-01 | 2004-04-15 | The Procter & Gamble Company | Tissue paper product, and process for making the product |
US6641826B2 (en) | 2000-06-26 | 2003-11-04 | Playtex Products, Inc. | Wipe with improved cleansing |
US20030031898A1 (en) * | 2001-08-03 | 2003-02-13 | Capps Charles L. | Antifungal gypsum board |
US6680127B2 (en) * | 2001-08-03 | 2004-01-20 | Temple-Inland Forest Products, Corporation | Antifungal gypsum board |
USRE40495E1 (en) * | 2001-09-19 | 2008-09-09 | Commun-I-Tec, Ltd. | Substrate treated with a binder comprising positive ions |
US6737068B2 (en) | 2001-10-01 | 2004-05-18 | Playtex Products, Inc. | Wipe formulation |
US20030157856A1 (en) * | 2002-01-14 | 2003-08-21 | Schroeder Gary L. | Moist wipe and method of making same |
US20060193990A1 (en) * | 2002-01-14 | 2006-08-31 | Fort James Corporation | Moist Wipe and Method of Making Same |
US20080254081A1 (en) * | 2002-01-14 | 2008-10-16 | Georgia-Pacific Consumer Products Lp | Moist Wipe and Method of Making Same |
US7530150B2 (en) | 2002-11-12 | 2009-05-12 | The Procter & Gamble Company | Process and apparatus for preparing a molded, textured, spunlaced, nonwoven web |
US20070273069A1 (en) * | 2002-11-12 | 2007-11-29 | Brennan Johnathan P | Process and apparatus for preparing a molded, textured, spunlaced, nonwoven web |
US20040116031A1 (en) * | 2002-11-12 | 2004-06-17 | Brennan Jonathan Paul | Process and apparatus for preparing a molded, textured, spunlaced, nonwoven web |
US11033563B2 (en) | 2005-08-30 | 2021-06-15 | Curemark, Llc | Use of lactulose in the treatment of autism |
US20070238383A1 (en) * | 2006-04-06 | 2007-10-11 | The Procter & Gamble Company | One-dimensional continuous molded element |
US7771648B2 (en) | 2006-04-06 | 2010-08-10 | The Procter & Gamble Company | One-dimensional continuous molded element |
US20100227139A1 (en) * | 2006-04-06 | 2010-09-09 | Astrid Annette Sheehan | One-Dimensional Continuous Molded Element |
US8389105B2 (en) | 2006-04-06 | 2013-03-05 | The Procter & Gamble Company | One-dimensional continuous molded element |
US20080118540A1 (en) * | 2006-11-22 | 2008-05-22 | Cmi Enterprises, Inc. | System and method for using nanoparticles for antimicrobial activity |
US20110038909A1 (en) * | 2006-11-22 | 2011-02-17 | Heirloom Holdings | System and Method for Using Nanoparticles for Antimicrobial Activity |
US11045527B2 (en) | 2008-03-13 | 2021-06-29 | Curemark, Llc | Method of diagnosing preeclampsia or pregnancy-induced hypertension |
US11235038B2 (en) | 2008-04-18 | 2022-02-01 | Curemark, Llc | Pharmaceutical preparation for the treatment of the symptoms of addiction and method of diagnosing same |
US11016104B2 (en) | 2008-07-01 | 2021-05-25 | Curemark, Llc | Methods and compositions for the treatment of symptoms of neurological and mental health disorders |
US20100065445A1 (en) * | 2008-09-18 | 2010-03-18 | Huckleberry Toys | Pre-Packaged, Customized, Woven, Wet Towel |
EP2947100A1 (en) | 2009-01-06 | 2015-11-25 | Curelon LLC | Oral compositions for the treatment or the prevention of infections by E. Coli |
EP3351264A1 (en) | 2009-01-06 | 2018-07-25 | Galenagen, LLC | Composition comprising protease, amylase and lipase |
EP3064217A1 (en) | 2009-01-06 | 2016-09-07 | Curelon LLC | Compositions comprising protease, amylase and lipase for use in the treatment of staphylococcus aureus infections |
US11357835B2 (en) | 2009-01-06 | 2022-06-14 | Galenagen, Llc | Compositions and methods for the treatment or the prevention of E. coli infections and for the eradication or reduction of E. coli surfaces |
US11419821B2 (en) | 2009-04-13 | 2022-08-23 | Curemark, Llc | Enzyme delivery systems and methods of preparation and use |
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Also Published As
Publication number | Publication date |
---|---|
DE2350036A1 (en) | 1974-05-22 |
CA1003329A (en) | 1977-01-11 |
JPS4977753A (en) | 1974-07-26 |
GB1416944A (en) | 1975-12-10 |
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