DE2350036A1 - PROCESS FOR MANUFACTURING PRE-MOISTURIZED ANTISEPTIC TOWELS - Google Patents

Description

Our No. 18 905

LAWYERS

DR .. JUR. DUL-CHEM. WALTER BEIL A OkI 1973

OLD HOEPPEHER

DR. } W. Df? L-CHEM. H.-J. WOtFF

DK. JUR. HAHS CHR. AX

623FRAHKFURTAMMAIN-HOCHsI

abeionstkasse »

Pfizer Inc.

New York, N.Y., V.St.A.

Process for making pre-moistened antiseptic towels'

The invention relates to a method for producing pre-moistened antimicrobial towels for sanitary purposes, e.g. for hemorrhoids, for feminine hygiene, for First aid, for cleaning when changing diapers and similar uses. ■. .

Heretofore, packs of pre-moistened towels have been made by placing a stack of towels in a container and then soaking them with a liquid containing an antimicrobial agent. The container was then closed and completely sealed by welding. However, this method is subject to chromatographic effects, whereby the antimicrobial agent can concentrate in parts of the stack ₅ and is therefore not evenly distributed over the stack and the individual towels.

409821 / 1CZG

According to the invention, the pre-moistened antimicrobial Towels are made by a process in which one has a rapier or textile strip with a solution of the antimicrobial agent impregnated in a volatile solvent that allows the solvent to evaporate, the impregnated Strips of tear-off towels perforated in the transverse direction, the perforated strip is folded lengthways and crossways, placing the folded, perforated strip in a stack in a moisture-proof container, this Stack soaked with aqueous liquid, and the container containing the moist stack with a moisture provides impermeable lid closure. The impregnation is preferably carried out using the gravure printing process,

In this procedure, the antimicrobial agent becomes uniform distributed on all towels. This prevents the product from becoming unusable and makes it uniform Concentration of the antimicrobial agent created for the intended use.

The invention is illustrated by the drawings,

Fig. 1 shows a schematic partial view in section represent a device with which the impregnation stage according to the invention is carried out.

Figure 2 is a side view of part of the apparatus of Figure 1 with part shown in section .

As Fig. 1 shows, a paper or textile strip 2 to a printing roller ¹ I, which is in rolling contact with a roll 6, guided past. Roller 6 is preferably a finely engraved application roller suitable for gravure printing. Roller H and roller 6 are rotated by a non-visible drive source in the directions indicated by arrows = A part of roller 6 x ^ is immersed in an anti-microbial solution 3, which is located in container 10) and which is about · =

Excessive solution is wiped off by doctor blade 12. the The incised or notched surface of the roller 6 is thereby moistened or soaked with the antimicrobial solution and in contact with the material to be impregnated brought when it runs through the slot between roller 4 and roller 6. The speed at which the material t runs through the rollers is not critical and can be adjusted as desired.

Suitably roll ¹ J has a resilient surface, for example made of rubber, is brought into close contact with the antimicrobial solution on the surface of the roll 6 whereby the strip 2 of paper or other sheet material.

Suitably, roller 6 is a conventional pressure roller, for example with a diameter of about 23 cm and a width of about 1.37 m. From Fig Pattern 14 is engraved or etched (in a greatly enlarged view), for example a series of cells or depressions, each in the form of an inverted rectangular truncated pyramid, in which the antimicrobial solution is held. This pattern, and in particular the size and the volume of the individual cells, are decisive for the amount of solution that is transferred to the strip 2 when the impregnation solution is applied. Preferred patterns have about 79 - cm 87 cells to 1, wherein each cell has a depth up to about 0.003 cm, and in a solution containing about 25 wt -.% Of the antimicrobial agent, typically 0.015 of this agent mg to 1 cm of the to impregnating surface are transferred. At concentrations of 4 to 50 wt -.% Can successfully 0.031 mg of the agent

to be deposited to 1 cm.

The towels are made of paper or hemp fleece, for example substantial wet strength, e.g., Dexter paper, Grade X 2067 or N 2660, available from Dexter Corp., Windsor

409821/1026

-Z ₁ -

Locks, Connecticut, USA _S “Woven or nonwoven fabrics made of rayon, mylon, or cotton, alone or in combination, can also be used.

Preferred antimicrobial compounds are the quaternary ammonium compounds, e.g., benzalkonium chloride ("Zephirol"), an alkyl substituted dimethylbenzylammonium chloride with, each B - l8 carbon atoms per Alkyl substituent. Change known antimicrobials such as cetylpyridinium chloride, chlorhexidine, or propyl or Fethylparaben can be used in full or in part of benzalkonium chloride can be used. The maximum amount the antimicrobial agent is determined by the particular one being used Means and the intended use of the product. Quaternary ammonium compounds are commonly used a concentration of 0.015 to 0.031 mg per 1 cm of the towel material is used. If necessary, in this stage optionally also more extensive components such as local anesthetics, Vasoconstrictors, astringents, etc. are applied. The volatile solvent is usually water, a mixture of water with ethanol or a mixture of water with isopropanol that forms by spontaneous evaporation the air dries.

After drying, the treated towel material is perforated in the transverse direction and folded lengthways and transversely, e.g. with a conventional zigzag folding machine that can perform a shear-cut transverse perforation, where ties between the individual towels remain, and the lengthways a "wing fold" and across a zigzag palte can lay. The term "perforate" means here that the towel material strips with a line transverse slits, which are defined by remaining pasier bonds, or provided with a transverse row of holes will.

40982.1 / 102.6

SAD QFüQh

By folding in a zigzag shape, the towels can be packed in stacks. The stack -Be in moisture sundurchlassige container packed _s eg flat polystyrene boxes _S and with an aqueous liquid such as water, water / ethanol or water / isopropanol, which may optionally contain auxiliary such as Geruehstoffe or the like _s moistened "The containers are then filled with a moisture- is, for example, top closure provided _s a reusable even after opening of the cover ₉ is suitably enclosed with a foil-reinforced paper, .the welded to an outwardly projecting tab on the container.

409821/10 26

Claims (3)

Patent claims: 1. A process for the production of pre-moistened antiseptic towels _s characterized in that a paper or textile strip is impregnated with a solution of an antimicrobial agent in a volatile solvent j the solvent evaporates, the impregnated strip is perforated to tear off towel parts in the transverse direction, the perforated strip longitudinally and transversely _s folds the folded and perforated strips in stack form in a moisture impermeable container brings soaked this stack with an aqueous liquid and provides the wet stack containing container having a moisture-impermeable cover closure. 2. The method according to claim 1 _s, characterized in that the impregnation is carried out by the gravure printing process. 3. The method of claim 1, characterized in that _s is used as the antimicrobial agent is a quaternary ammonium compound such as benzalkonium chloride. H. The method according to claim 1, characterized in that hemp fleece is used as the textile strip. For: Pfizer Dr, H.J.Wolff Lawyer 409821/1 026