ZA795239B - Heterocyclic compounds - Google Patents

Heterocyclic compounds

Info

Publication number
ZA795239B
ZA795239B ZA00795239A ZA795239A ZA795239B ZA 795239 B ZA795239 B ZA 795239B ZA 00795239 A ZA00795239 A ZA 00795239A ZA 795239 A ZA795239 A ZA 795239A ZA 795239 B ZA795239 B ZA 795239B
Authority
ZA
South Africa
Prior art keywords
heterocyclic compounds
heterocyclic
compounds
Prior art date
Application number
ZA00795239A
Other languages
English (en)
Inventor
C Webb
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ZA795239B publication Critical patent/ZA795239B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA00795239A 1978-10-12 1979-10-02 Heterocyclic compounds ZA795239B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7840279 1978-10-12

Publications (1)

Publication Number Publication Date
ZA795239B true ZA795239B (en) 1980-11-26

Family

ID=10500283

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00795239A ZA795239B (en) 1978-10-12 1979-10-02 Heterocyclic compounds

Country Status (18)

Country Link
US (1) US4252803A (cs)
JP (1) JPS5562063A (cs)
AU (1) AU531783B2 (cs)
BE (1) BE879381A (cs)
CA (1) CA1146550A (cs)
CH (1) CH646151A5 (cs)
DE (1) DE2940687A1 (cs)
DK (1) DK425579A (cs)
ES (2) ES484980A0 (cs)
FI (1) FI793071A7 (cs)
FR (1) FR2438651A1 (cs)
GB (1) GB2035310B (cs)
IE (1) IE49304B1 (cs)
IT (1) IT1142170B (cs)
NL (1) NL7907583A (cs)
NZ (1) NZ191802A (cs)
SE (1) SE448628B (cs)
ZA (1) ZA795239B (cs)

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DE3131728A1 (de) * 1980-08-12 1982-03-11 Glaxo Group Ltd., London Indolverbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
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US4428962A (en) 1981-10-30 1984-01-31 Schering Corporation Indoles in treatment of peptic ulcers
IT1170387B (it) * 1982-06-07 1987-06-03 Glaxo Group Ltd Composti eterociclici, procedimento per prepararli e composizioni farmaceutiche che li contengono
US4582848A (en) * 1982-06-10 1986-04-15 Sandoz, Inc. 2-substituted-3-indolamines and use thereof as anti-diabetics
US4803218A (en) * 1982-09-29 1989-02-07 Mcneilab, Inc. 3-aminoalkyl-1H-indole-5-urea and amide derivatives
US4622399A (en) * 1983-06-30 1986-11-11 American Home Products Corporation Bicyclo-heterocyclic nitrogen substituted aminoethanol derivatives
US4521606A (en) * 1983-06-30 1985-06-04 American Home Products Corp. 5-Indolyl substituted aminoethanols
US4562200A (en) * 1983-06-30 1985-12-31 American Home Products Corporation 5(Indolyl) and 5(2,3-dihydroindolyl) substituted aminoethanols and their use as anti-hypertensives
GB8332435D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
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GB8419575D0 (en) * 1984-08-01 1984-09-05 Glaxo Group Ltd Chemical compounds
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DE3537289A1 (de) * 1985-10-19 1987-04-23 Hoechst Ag 2-(3-brompropyl)-5,5-dimethyl-1,3-dioxan, sowie verfahren zur herstellung desselben und des 2-(4-brombutyl)-5,5-dimethyl-1,3-dioxans
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GB8530507D0 (en) * 1985-12-11 1986-01-22 Glaxo Group Plc Chemical compounds
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8600397D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8607824D0 (en) * 1986-03-27 1986-04-30 Glaxo Group Ltd Chemical compounds
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GB8614287D0 (en) * 1986-06-12 1986-07-16 Glaxo Group Ltd Chemical compounds
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US5276045A (en) * 1989-06-16 1994-01-04 Rhone-Poulenc Sante Thioformamide derivative, process for its preparation, pharmaceutical composition thereof and treatment method
CA2042295A1 (fr) * 1990-05-15 1991-11-16 Jacques Chauveau Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant
CA2282890C (en) * 1990-06-07 2001-07-31 The Wellcome Foundation Limited Therapeutic heterocyclic compounds
US5229409A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-tetrahydrobenz[cd]indoles
US5559246A (en) * 1990-10-15 1996-09-24 Pfizer Inc. Indole derivatives
US5607951A (en) * 1990-10-15 1997-03-04 Pfizer Inc Indole derivatives
US5559129A (en) * 1990-10-15 1996-09-24 Pfizer Inc Indole derivatives
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
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US5364856A (en) * 1991-03-28 1994-11-15 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
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US6380233B1 (en) 1992-04-07 2002-04-30 Pfizer Inc Indole derivatives as 5-HT1 agonists
CZ281763B6 (cs) 1992-04-07 1997-01-15 Pfizer Inc. Indolové deriváty představující 5-HT1 agonisty, způsob jejich přípravy, farmaceutické prostředky obsahující tyto látky, jejich použití a meziprodukty postupu přípravy
GB9207930D0 (en) * 1992-04-10 1992-05-27 Pfizer Ltd Indoles
DE69307875T2 (de) * 1992-04-10 1997-05-22 Pfizer Acylaminoindolderivate als 5-ht1 agonisten
TW251284B (cs) * 1992-11-02 1995-07-11 Pfizer
GB9226566D0 (en) * 1992-12-21 1993-02-17 Smithkline Beecham Plc Compounds
WO1995006636A1 (en) * 1993-08-31 1995-03-09 Pfizer Inc. 5-arylindole derivatives
US5468768A (en) * 1994-01-06 1995-11-21 Bristol-Myers Squibb Company Antimigraine derivatives of indolylcycloalkanylamines
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US5780437A (en) * 1995-12-14 1998-07-14 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
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US3182071A (en) * 1961-06-27 1965-05-04 Warner Lambert Pharmaceutical Acylated indole derivatives
NL7316677A (cs) * 1972-12-21 1974-06-25
DE2314489A1 (de) * 1973-03-23 1974-10-03 Thomae Gmbh Dr K (+)-3-(2-dimethylamino-1-propyl)-2methyl-3-phenyl-3h-indol, dessen saeureadditionssalze und verfahren zu deren herstellung
US3997539A (en) * 1974-05-31 1976-12-14 American Hoechst Corporation 3-(4-Acylaminopiperazin-1-yl alkyl)indoles, precursors and processes for the preparation thereof

Also Published As

Publication number Publication date
DE2940687A1 (de) 1980-04-30
AU531783B2 (en) 1983-09-08
ES8106142A1 (es) 1981-07-16
ES8100261A1 (es) 1980-11-01
GB2035310A (en) 1980-06-18
DK425579A (da) 1980-04-13
SE7908443L (sv) 1980-04-13
US4252803A (en) 1981-02-24
FR2438651A1 (fr) 1980-05-09
DE2940687C2 (cs) 1991-08-01
IT1142170B (it) 1986-10-08
CA1146550A (en) 1983-05-17
JPS5562063A (en) 1980-05-10
NL7907583A (nl) 1980-04-15
CH646151A5 (de) 1984-11-15
IE791945L (en) 1980-04-12
ES484980A0 (es) 1980-11-01
IT7950537A0 (it) 1979-10-11
FR2438651B1 (cs) 1983-03-04
AU5165779A (en) 1980-04-17
JPS6358817B2 (cs) 1988-11-17
GB2035310B (en) 1982-12-22
NZ191802A (en) 1983-02-15
BE879381A (fr) 1980-02-01
SE448628B (sv) 1987-03-09
ES492114A0 (es) 1981-07-16
IE49304B1 (en) 1985-09-18
FI793071A7 (fi) 1981-01-01

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