BE879381A - Nouveaux indoles, leur preparation et compositions les contenant - Google Patents

Nouveaux indoles, leur preparation et compositions les contenant

Info

Publication number
BE879381A
BE879381A BE0/197621A BE197621A BE879381A BE 879381 A BE879381 A BE 879381A BE 0/197621 A BE0/197621 A BE 0/197621A BE 197621 A BE197621 A BE 197621A BE 879381 A BE879381 A BE 879381A
Authority
BE
Belgium
Prior art keywords
preparation
compositions containing
new indoles
indoles
new
Prior art date
Application number
BE0/197621A
Other languages
English (en)
Inventor
C Webb
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of BE879381A publication Critical patent/BE879381A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BE0/197621A 1978-10-12 1979-10-12 Nouveaux indoles, leur preparation et compositions les contenant BE879381A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7840279 1978-10-12

Publications (1)

Publication Number Publication Date
BE879381A true BE879381A (fr) 1980-02-01

Family

ID=10500283

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/197621A BE879381A (fr) 1978-10-12 1979-10-12 Nouveaux indoles, leur preparation et compositions les contenant

Country Status (18)

Country Link
US (1) US4252803A (fr)
JP (1) JPS5562063A (fr)
AU (1) AU531783B2 (fr)
BE (1) BE879381A (fr)
CA (1) CA1146550A (fr)
CH (1) CH646151A5 (fr)
DE (1) DE2940687A1 (fr)
DK (1) DK425579A (fr)
ES (2) ES8100261A1 (fr)
FI (1) FI793071A (fr)
FR (1) FR2438651A1 (fr)
GB (1) GB2035310B (fr)
IE (1) IE49304B1 (fr)
IT (1) IT1142170B (fr)
NL (1) NL7907583A (fr)
NZ (1) NZ191802A (fr)
SE (1) SE448628B (fr)
ZA (1) ZA795239B (fr)

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997021703A1 (fr) * 1995-12-14 1997-06-19 Merck & Co., Inc. Antagonistes de l'hormone de liberaiton de la gonadotropine
WO1997021704A1 (fr) * 1995-12-14 1997-06-19 Merck & Co., Inc. Antagonistes de l'hormone de liberation de la gonadotropine
US5981550A (en) * 1997-06-05 1999-11-09 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US5985901A (en) * 1997-06-05 1999-11-16 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US5998432A (en) * 1998-04-02 1999-12-07 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6004984A (en) * 1997-06-05 1999-12-21 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6025366A (en) * 1998-04-02 2000-02-15 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6077847A (en) * 1998-04-02 2000-06-20 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6156772A (en) * 1997-06-05 2000-12-05 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6156767A (en) * 1997-06-05 2000-12-05 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6159975A (en) * 1998-02-11 2000-12-12 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6172080B1 (en) 1999-03-10 2001-01-09 Merck & Co., Inc. 6-azaindole compounds as antagonists of gonadotropin releasing hormone
US6180642B1 (en) 1999-03-10 2001-01-30 Merck & Co., Inc. 6-azaindole compounds as antagonists of Gonadotropin releasing hormone
US6228867B1 (en) 1998-04-02 2001-05-08 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6288078B1 (en) 1999-03-10 2001-09-11 Merck & Co., Inc. 6-azaindole compounds as antagonists of gonadotropin releasing hormone
US6620824B2 (en) 2001-04-11 2003-09-16 Merck & Co., Inc. Process for the synthesis of gonadotropin releasing hormone antagonists

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU550010B2 (en) * 1980-08-12 1986-02-27 Glaxo Group Limited 5-tryptaminoacetamides, carbamates and ureas
BE889931A (fr) * 1980-08-12 1982-02-11 Glaxo Group Ltd Derives indoliques, leur preparation et leurs applications en tant que medicaments
AT381491B (de) * 1980-08-12 1986-10-27 Glaxo Group Ltd Verfahren zur herstellung von neuen indolverbindungen und ihren salzen
ES504693A0 (es) * 1980-08-12 1982-12-01 Glaxo Group Ltd Un procedimiento para la preparacion de un derivado del indol.
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
US4428962A (en) 1981-10-30 1984-01-31 Schering Corporation Indoles in treatment of peptic ulcers
GR79215B (fr) * 1982-06-07 1984-10-22 Glaxo Group Ltd
US4582848A (en) * 1982-06-10 1986-04-15 Sandoz, Inc. 2-substituted-3-indolamines and use thereof as anti-diabetics
US4803218A (en) * 1982-09-29 1989-02-07 Mcneilab, Inc. 3-aminoalkyl-1H-indole-5-urea and amide derivatives
US4622399A (en) * 1983-06-30 1986-11-11 American Home Products Corporation Bicyclo-heterocyclic nitrogen substituted aminoethanol derivatives
US4562200A (en) * 1983-06-30 1985-12-31 American Home Products Corporation 5(Indolyl) and 5(2,3-dihydroindolyl) substituted aminoethanols and their use as anti-hypertensives
US4521606A (en) * 1983-06-30 1985-06-04 American Home Products Corp. 5-Indolyl substituted aminoethanols
HU196752B (en) * 1983-12-06 1989-01-30 Glaxo Group Ltd Process for production of medical compositions containing indole-derivatives and these compounds
GB8332437D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
AU571922B2 (en) * 1984-01-26 1988-04-28 Schering Agrochemicals Limited Veterinary implants comprising melatonin and derivatives thereof
US5026869A (en) * 1984-02-06 1991-06-25 Eli Lilly And Company 6-substituted-4-dialkylaminotetrahydrobenz(c,d)indoles
GB8419575D0 (en) * 1984-08-01 1984-09-05 Glaxo Group Ltd Chemical compounds
GB8431426D0 (en) * 1984-12-13 1985-01-23 Glaxo Group Ltd Chemical compounds
DE3537289A1 (de) * 1985-10-19 1987-04-23 Hoechst Ag 2-(3-brompropyl)-5,5-dimethyl-1,3-dioxan, sowie verfahren zur herstellung desselben und des 2-(4-brombutyl)-5,5-dimethyl-1,3-dioxans
US4833153A (en) * 1985-11-08 1989-05-23 Glaxo Group Limited Indole derivatives
GB8530507D0 (en) * 1985-12-11 1986-01-22 Glaxo Group Plc Chemical compounds
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8600397D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8607824D0 (en) * 1986-03-27 1986-04-30 Glaxo Group Ltd Chemical compounds
AU601736B2 (en) * 1986-05-23 1990-09-20 Sanofi Sante Nutrition Animale Sa Coated veterinary implants
GB8614287D0 (en) * 1986-06-12 1986-07-16 Glaxo Group Ltd Chemical compounds
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8830312D0 (en) * 1988-12-28 1989-02-22 Lundbeck & Co As H Heterocyclic compounds
US5276045A (en) * 1989-06-16 1994-01-04 Rhone-Poulenc Sante Thioformamide derivative, process for its preparation, pharmaceutical composition thereof and treatment method
CA2042295A1 (fr) * 1990-05-15 1991-11-16 Jacques Chauveau Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant
RU2160736C2 (ru) * 1990-06-07 2000-12-20 Зенека Лимитед Производные индола и их физиологически приемлемые соли и сольваты, способы их получения, лекарственное средство для лечения или профилактики клинических состояний, для которых показан прием агониста "5-нт1-подобного" рецептора, и способ его получения
US5229409A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-tetrahydrobenz[cd]indoles
US5607951A (en) * 1990-10-15 1997-03-04 Pfizer Inc Indole derivatives
US5559246A (en) * 1990-10-15 1996-09-24 Pfizer Inc. Indole derivatives
US5559129A (en) * 1990-10-15 1996-09-24 Pfizer Inc Indole derivatives
US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
DE4101686A1 (de) * 1991-01-22 1992-07-23 Merck Patent Gmbh Indolderivate
CZ283018B6 (cs) * 1991-02-01 1997-12-17 Merck Sharp And Dohme Limited Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi
US5244912A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof
US5364856A (en) * 1991-03-28 1994-11-15 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
DK0619805T3 (da) * 1991-11-25 2000-06-05 Pfizer 5-(Hetero-eller carbocyclylamino)-indolderivater, deres fremstilling og anvendelse som 5-HT1-agonister
TW288010B (fr) * 1992-03-05 1996-10-11 Pfizer
US6380233B1 (en) 1992-04-07 2002-04-30 Pfizer Inc Indole derivatives as 5-HT1 agonists
RU2101283C1 (ru) 1992-04-07 1998-01-10 Пфайзер Инк. Производные индола или их фармацевтически приемлемые соли
ATE148465T1 (de) * 1992-04-10 1997-02-15 Pfizer Acylaminoindolderivate als 5-ht1 agonisten
GB9207930D0 (en) * 1992-04-10 1992-05-27 Pfizer Ltd Indoles
TW251284B (fr) * 1992-11-02 1995-07-11 Pfizer
GB9226566D0 (en) * 1992-12-21 1993-02-17 Smithkline Beecham Plc Compounds
JP2860603B2 (ja) * 1993-08-31 1999-02-24 ファイザー・インク． ５−アリールインドール誘導体
US5468768A (en) * 1994-01-06 1995-11-21 Bristol-Myers Squibb Company Antimigraine derivatives of indolylcycloalkanylamines
GB9417310D0 (en) * 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
EA000828B1 (ru) 1995-12-14 2000-04-24 Мерк Энд Ко., Инк. Антагонисты гонадотропин-высвобождающего фактора
US5849764A (en) * 1995-12-14 1998-12-15 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US5756507A (en) * 1995-12-14 1998-05-26 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6200957B1 (en) 1995-12-14 2001-03-13 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US5780437A (en) * 1995-12-14 1998-07-14 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
EP0875513A1 (fr) * 1997-04-14 1998-11-04 Eli Lilly And Company Composés hétéroaromatiques substitués agonistes du récepteur 5-HT1F
CA2292881A1 (fr) * 1997-06-05 1998-12-10 Merck & Co., Inc. Antagonistes de gonadoliberine
EP0994708A1 (fr) * 1997-06-05 2000-04-26 Merck & Co., Inc. Antagonistes de l'hormone de liberation de la gonadotrophine
US6017944A (en) * 1997-10-28 2000-01-25 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
WO1999021553A1 (fr) * 1997-10-28 1999-05-06 Merck & Co., Inc. Antagonistes de l'hormone de liberation de la gonadothrophine
US5994352A (en) * 1998-11-13 1999-11-30 Pfizer Inc. 5-arylindole derivatives
EP2335700A1 (fr) * 2001-07-25 2011-06-22 Boehringer Ingelheim (Canada) Ltd. Inhibiteurs de la polymerase du virus hepatitis C avec une structure heterobicylic
DK1537113T5 (da) 2002-06-21 2011-01-10 Suven Life Sciences Ltd Arylalkylindoler med serotoninreceptoraffinitet anvendelige som terapeutiske midler, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse
CA2490254C (fr) 2002-06-21 2011-11-01 Suven Life Sciences Limited Nouveaux indoles tetracycliques arylsulfonyle ayant une affinite du recepteur de la serotonine et utiles comme agents therapeutiques, leur procede de preparation et compositions pharmaceutiques les contenant
NZ572186A (en) 2002-11-28 2010-02-26 Suven Life Sciences Ltd N-arylsulfonyl-3-substituted indoles having serotonin receptor affinity, process for their preparation and pharmaceutical composition containing them
BRPI0315958B8 (pt) 2002-11-28 2021-05-25 Suven Life Sciences Ltd composto, composição farmacêutica, processo para a preparação de um composto, novos intermediários e uso do composto
CN1729174B (zh) * 2002-12-20 2015-10-21 西巴特殊化学品控股有限公司 胺的合成以及用于合成胺的中间体
US7223785B2 (en) * 2003-01-22 2007-05-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
US7098231B2 (en) * 2003-01-22 2006-08-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
ES2431314T3 (es) * 2004-02-20 2013-11-26 Boehringer Ingelheim International Gmbh Inhibidores de polimerasa vírica
CA2618682C (fr) * 2005-08-12 2011-06-21 Boehringer Ingelheim International Gmbh Inhibiteurs de polymerase virale
WO2011124704A1 (fr) * 2010-04-09 2011-10-13 Ratiopharm Gmbh Procédé de préparation d'un intermédiaire pour la silodosine
WO2022104475A1 (fr) * 2020-11-19 2022-05-27 Magicmed Industries Inc. Dérivés de psilocybine nitrilés et leurs procédés d'utilisation
WO2023076150A1 (fr) * 2021-10-29 2023-05-04 Psilera Inc. Composés d'indole modifiés

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3182071A (en) * 1961-06-27 1965-05-04 Warner Lambert Pharmaceutical Acylated indole derivatives
NL7316677A (fr) * 1972-12-21 1974-06-25
DE2314489A1 (de) * 1973-03-23 1974-10-03 Thomae Gmbh Dr K (+)-3-(2-dimethylamino-1-propyl)-2methyl-3-phenyl-3h-indol, dessen saeureadditionssalze und verfahren zu deren herstellung
US3997539A (en) * 1974-05-31 1976-12-14 American Hoechst Corporation 3-(4-Acylaminopiperazin-1-yl alkyl)indoles, precursors and processes for the preparation thereof

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997021704A1 (fr) * 1995-12-14 1997-06-19 Merck & Co., Inc. Antagonistes de l'hormone de liberation de la gonadotropine
WO1997021703A1 (fr) * 1995-12-14 1997-06-19 Merck & Co., Inc. Antagonistes de l'hormone de liberaiton de la gonadotropine
EA000829B1 (ru) * 1995-12-14 2000-04-24 Мерк Энд Ко., Инк. Антагонисты гонадотропин-высвобождающего фактора
US6156772A (en) * 1997-06-05 2000-12-05 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US5981550A (en) * 1997-06-05 1999-11-09 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US5985901A (en) * 1997-06-05 1999-11-16 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6004984A (en) * 1997-06-05 1999-12-21 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6156767A (en) * 1997-06-05 2000-12-05 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6077858A (en) * 1997-06-05 2000-06-20 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6159975A (en) * 1998-02-11 2000-12-12 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6077847A (en) * 1998-04-02 2000-06-20 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6025366A (en) * 1998-04-02 2000-02-15 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US5998432A (en) * 1998-04-02 1999-12-07 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6228867B1 (en) 1998-04-02 2001-05-08 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6172080B1 (en) 1999-03-10 2001-01-09 Merck & Co., Inc. 6-azaindole compounds as antagonists of gonadotropin releasing hormone
US6180642B1 (en) 1999-03-10 2001-01-30 Merck & Co., Inc. 6-azaindole compounds as antagonists of Gonadotropin releasing hormone
US6288078B1 (en) 1999-03-10 2001-09-11 Merck & Co., Inc. 6-azaindole compounds as antagonists of gonadotropin releasing hormone
US6620824B2 (en) 2001-04-11 2003-09-16 Merck & Co., Inc. Process for the synthesis of gonadotropin releasing hormone antagonists

Also Published As

Publication number Publication date
IT1142170B (it) 1986-10-08
SE448628B (sv) 1987-03-09
JPS5562063A (en) 1980-05-10
NL7907583A (nl) 1980-04-15
AU531783B2 (en) 1983-09-08
ES8106142A1 (es) 1981-07-16
NZ191802A (en) 1983-02-15
DE2940687A1 (de) 1980-04-30
IE791945L (en) 1980-04-12
FR2438651A1 (fr) 1980-05-09
DE2940687C2 (fr) 1991-08-01
ES492114A0 (es) 1981-07-16
IT7950537A0 (it) 1979-10-11
AU5165779A (en) 1980-04-17
US4252803A (en) 1981-02-24
ES484980A0 (es) 1980-11-01
GB2035310B (en) 1982-12-22
FI793071A (fi) 1980-04-13
DK425579A (da) 1980-04-13
FR2438651B1 (fr) 1983-03-04
SE7908443L (sv) 1980-04-13
CA1146550A (fr) 1983-05-17
JPS6358817B2 (fr) 1988-11-17
IE49304B1 (en) 1985-09-18
GB2035310A (en) 1980-06-18
ZA795239B (en) 1980-11-26
CH646151A5 (de) 1984-11-15
ES8100261A1 (es) 1980-11-01

Similar Documents

Publication Publication Date Title
BE879381A (fr) Nouveaux indoles, leur preparation et compositions les contenant
BE835325A (fr) Nouveaux composes heterocycliques, leur preparation et compositions qui les contiennent
BE771493A (fr) Nouveaux derives de l'isoindoline, leur preparation et les compositionsqui les contiennent
FR2347365A1 (fr) Trans-hexahydro-pyrido-indoles, leur preparation et compositions pharmaceutiques les contenant
BE838194A (fr) Nouveaux derives de l'oxadiazolinone, leur preparation et les compositions qui les contiennent
BE864862A (fr) Nouveaux benzylidene camphres, leur procede de preparation et compositions cosmetiques les contenant
LU78895A1 (fr) Nouveaux derives de l'isoquinoleine,leur preparation et les compositions qui les contiennent
BE856628A (fr) Nouveaux metaaminophenols et compositions tinctoriales les contenant
LU81182A1 (fr) Nouveaux derives de l'isoquinoleine,leur preparation et les compositions pharmaceutiques qui les contiennent
FR2340310A1 (fr) Hydrazinophtalazines substituees, leur preparation et compositions pharmaceutiques les contenant
FR2521142B1 (fr) Nouveaux derives n-methanesulfonique de la demethyl-3-o istamycine b, leur preparation et compositions therapeutiques en contenant
BE869485A (fr) Nouveaux derives de la doxorubicine, leur preparation et les compositions qui les contiennent
PT65574A (fr) Nouveaux derives de l'oxadiazine-1,2,4 one-5,leur preparation et les compositions les contenant
PT64976A (fr) Nouveaux composes heterocycliques,leur preparation et les compositions qui les contiennent
BE863083A (fr) Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent
BE867129A (fr) Nouveaux derives de l'hydroxy-4 thiazolidinethione-2, leur preparation et les compositions qui les contiennent
BE888963A (fr) Compositions cardiotoniques contenant des aminophenylpyridines, nouvelles aminophenylpyridines et leur preparation
BE835324A (fr) Nouveaux derives de l'oxathiinno (1,4) (2, 3, -c) pyrrole, leur preparation et les compositions qui les contiennent
LU80497A1 (fr) Nouveaux derives de l'isoquinoleine,leur preparation et les compositions qui les contiennent
BE840428A (fr) Nouveaux composes heterocycliques, leur preparation et les compositions qui les contiennent
FR2324305A2 (fr) Nouveaux derives de l'isoindoline, leur preparation et les compositions qui les contiennent
FR2309554A1 (fr) Nouveaux carbamates de benzodioxolyle, leur procede de preparation et composition insecticide les contenant
BE839401A (fr) Nouveaux derives phosphores, leur preparation et les compositions qui les contiennent
BE875797A (fr) NOUVEAUX DERIVES DE L'ISOQUINOLEINE, LEUR PREPARATION ET LES COMPOSITIONS àPHARMACEUTIQUES QUI LES CONTIENNENT
PT70438A (fr) Nouveaux derives de la perhydrothiazine-1,3 leur preparation et les medicaments qui les contiennent

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: GLAXO GROUP LTD

Effective date: 19911031