IT7950537A0 - Composti eterociclici dotati di attivita' farmacologica e procedimento per la loro preparazione - Google Patents

Composti eterociclici dotati di attivita' farmacologica e procedimento per la loro preparazione

Info

Publication number
IT7950537A0
IT7950537A0 IT7950537A IT5053779A IT7950537A0 IT 7950537 A0 IT7950537 A0 IT 7950537A0 IT 7950537 A IT7950537 A IT 7950537A IT 5053779 A IT5053779 A IT 5053779A IT 7950537 A0 IT7950537 A0 IT 7950537A0
Authority
IT
Italy
Prior art keywords
procedure
preparation
pharmacological activity
heterociclic compounds
compounds equipped
Prior art date
Application number
IT7950537A
Other languages
English (en)
Other versions
IT1142170B (it
Inventor
Colin Frederick Webb
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of IT7950537A0 publication Critical patent/IT7950537A0/it
Application granted granted Critical
Publication of IT1142170B publication Critical patent/IT1142170B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
IT50537/79A 1978-10-12 1979-10-11 Composti eterosiclici dotati di attivita' farmacologica e procedimento per la loro preparazione IT1142170B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7840279 1978-10-12

Publications (2)

Publication Number Publication Date
IT7950537A0 true IT7950537A0 (it) 1979-10-11
IT1142170B IT1142170B (it) 1986-10-08

Family

ID=10500283

Family Applications (1)

Application Number Title Priority Date Filing Date
IT50537/79A IT1142170B (it) 1978-10-12 1979-10-11 Composti eterosiclici dotati di attivita' farmacologica e procedimento per la loro preparazione

Country Status (18)

Country Link
US (1) US4252803A (it)
JP (1) JPS5562063A (it)
AU (1) AU531783B2 (it)
BE (1) BE879381A (it)
CA (1) CA1146550A (it)
CH (1) CH646151A5 (it)
DE (1) DE2940687A1 (it)
DK (1) DK425579A (it)
ES (2) ES8100261A1 (it)
FI (1) FI793071A (it)
FR (1) FR2438651A1 (it)
GB (1) GB2035310B (it)
IE (1) IE49304B1 (it)
IT (1) IT1142170B (it)
NL (1) NL7907583A (it)
NZ (1) NZ191802A (it)
SE (1) SE448628B (it)
ZA (1) ZA795239B (it)

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BE889931A (fr) * 1980-08-12 1982-02-11 Glaxo Group Ltd Derives indoliques, leur preparation et leurs applications en tant que medicaments
AT381491B (de) * 1980-08-12 1986-10-27 Glaxo Group Ltd Verfahren zur herstellung von neuen indolverbindungen und ihren salzen
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
US4428962A (en) 1981-10-30 1984-01-31 Schering Corporation Indoles in treatment of peptic ulcers
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US4622399A (en) * 1983-06-30 1986-11-11 American Home Products Corporation Bicyclo-heterocyclic nitrogen substituted aminoethanol derivatives
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GB8332437D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
HU196752B (en) * 1983-12-06 1989-01-30 Glaxo Group Ltd Process for production of medical compositions containing indole-derivatives and these compounds
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DE3537289A1 (de) * 1985-10-19 1987-04-23 Hoechst Ag 2-(3-brompropyl)-5,5-dimethyl-1,3-dioxan, sowie verfahren zur herstellung desselben und des 2-(4-brombutyl)-5,5-dimethyl-1,3-dioxans
DE3678805D1 (de) * 1985-11-08 1991-05-23 Glaxo Group Ltd Indolderivate.
GB8530507D0 (en) * 1985-12-11 1986-01-22 Glaxo Group Plc Chemical compounds
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8600397D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8607824D0 (en) * 1986-03-27 1986-04-30 Glaxo Group Ltd Chemical compounds
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US5364856A (en) * 1991-03-28 1994-11-15 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
US5639752A (en) * 1991-11-25 1997-06-17 Pfizer Inc Indole derivatives
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US6380233B1 (en) 1992-04-07 2002-04-30 Pfizer Inc Indole derivatives as 5-HT1 agonists
US5747501A (en) 1992-04-07 1998-05-05 Pfizer, Inc. Indole derivatives
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WO1993021180A1 (en) * 1992-04-10 1993-10-28 Pfizer Inc. Acylaminoindole derivatives as 5-ht1 agonists
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GB9226566D0 (en) * 1992-12-21 1993-02-17 Smithkline Beecham Plc Compounds
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US5468768A (en) * 1994-01-06 1995-11-21 Bristol-Myers Squibb Company Antimigraine derivatives of indolylcycloalkanylamines
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US5780437A (en) * 1995-12-14 1998-07-14 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
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CZ183198A3 (cs) 1995-12-14 1998-10-14 Merck And Co., Inc. Nepeptidové deriváty, antagonizující hormon, uvolňující gonadotropin a farmaceutický prostředek
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US5985901A (en) * 1997-06-05 1999-11-16 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6156767A (en) * 1997-06-05 2000-12-05 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6004984A (en) * 1997-06-05 1999-12-21 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US5981550A (en) * 1997-06-05 1999-11-09 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
JP2002502428A (ja) * 1997-06-05 2002-01-22 メルク エンド カンパニー インコーポレーテッド ゴナドトロピン放出ホルモンの拮抗薬
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US6017944A (en) * 1997-10-28 2000-01-25 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
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US3182071A (en) * 1961-06-27 1965-05-04 Warner Lambert Pharmaceutical Acylated indole derivatives
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DE2314489A1 (de) * 1973-03-23 1974-10-03 Thomae Gmbh Dr K (+)-3-(2-dimethylamino-1-propyl)-2methyl-3-phenyl-3h-indol, dessen saeureadditionssalze und verfahren zu deren herstellung
US3997539A (en) * 1974-05-31 1976-12-14 American Hoechst Corporation 3-(4-Acylaminopiperazin-1-yl alkyl)indoles, precursors and processes for the preparation thereof

Also Published As

Publication number Publication date
ES492114A0 (es) 1981-07-16
US4252803A (en) 1981-02-24
DK425579A (da) 1980-04-13
JPS5562063A (en) 1980-05-10
IT1142170B (it) 1986-10-08
ES8106142A1 (es) 1981-07-16
ZA795239B (en) 1980-11-26
SE448628B (sv) 1987-03-09
FR2438651B1 (it) 1983-03-04
AU531783B2 (en) 1983-09-08
IE49304B1 (en) 1985-09-18
CH646151A5 (de) 1984-11-15
DE2940687A1 (de) 1980-04-30
GB2035310B (en) 1982-12-22
SE7908443L (sv) 1980-04-13
DE2940687C2 (it) 1991-08-01
FI793071A (fi) 1980-04-13
BE879381A (fr) 1980-02-01
AU5165779A (en) 1980-04-17
FR2438651A1 (fr) 1980-05-09
ES484980A0 (es) 1980-11-01
GB2035310A (en) 1980-06-18
ES8100261A1 (es) 1980-11-01
IE791945L (en) 1980-04-12
JPS6358817B2 (it) 1988-11-17
NZ191802A (en) 1983-02-15
CA1146550A (en) 1983-05-17
NL7907583A (nl) 1980-04-15

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